Works by Stringham, Heather

Results: 28

The Role of Environmental Heterogeneity in Meta-Analysis of Gene-Environment Interactions With Quantitative Traits.

Published in:

Genetic Epidemiology, 2014, v. 38, n. 5, p. 416, doi. 10.1002/gepi.21810

By:

Li, Shi;
Mukherjee, Bhramar;
Taylor, Jeremy M. G.;
Rice, Kenneth M.;
Wen, Xiaoquan;
Rice, John D.;
Stringham, Heather M.;
Boehnke, Michael

Publication type:

Article

Lod scores for gene mapping in the presence of marker map uncertainty.

Published in:

Genetic Epidemiology, 2001, v. 21, n. 1, p. 31, doi. 10.1002/gepi.1016

By:

Stringham, Heather M.;
Boehnke, Michael

Publication type:

Article

Assessing the potential causal effects of 1099 plasma metabolites on 2099 binary disease endpoints.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58129-2

By:

Yin, Xianyong;
Li, Jack;
Bose, Debraj;
Okamoto, Jeffrey;
Kwon, Annie;
Jackson, Anne U.;
Fernandes Silva, Lilian;
Oravilahti, Anniina;
Chu, Xiaomeng;
Stringham, Heather M.;
Liu, Lei;
Peng, Ruyi;
Xia, Zhijie;
Ripatti, Samuli;
Daly, Mark;
Palotie, Aarno;
Scott, Laura J.;
Burant, Charles F.;
Fauman, Eric B.;
Wen, Xiaoquan

Publication type:

Article

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29143-5

By:

Yin, Xianyong;
Chan, Lap Sum;
Bose, Debraj;
Jackson, Anne U.;
VandeHaar, Peter;
Locke, Adam E.;
Fuchsberger, Christian;
Stringham, Heather M.;
Welch, Ryan;
Yu, Ketian;
Fernandes Silva, Lilian;
Service, Susan K.;
Zhang, Daiwei;
Hector, Emily C.;
Young, Erica;
Ganel, Liron;
Das, Indraniel;
Abel, Haley;
Erdos, Michael R.;
Bonnycastle, Lori L.

Publication type:

Article

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Published in:

Nature Genetics, 2010, v. 42, n. 11, p. 937, doi. 10.1038/ng.686

By:

Speliotes, Elizabeth K.;
Willer, Cristen J.;
Berndt, Sonja I.;
Monda, Keri L.;
Thorleifsson, Gudmar;
Jackson, Anne U.;
Allen, Hana Lango;
Lindgren, Cecilia M.;
Luan, Jian'an;
Mägi, Reedik;
Randall, Joshua C.;
Vedantam, Sailaja;
Winkler, Thomas W.;
Lu Qi;
Workalemahu, Tsegaselassie;
Heid, Iris M.;
Steinthorsdottir, Valgerdur;
Stringham, Heather M.;
Weedon, Michael N.;
Wheeler, Eleanor

Publication type:

Article

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.

Published in:

Nature Genetics, 2010, v. 42, n. 2, p. 142, doi. 10.1038/ng.521

By:

Saxena, Richa;
Hivert, Marie-France;
Langenberg, Claudia;
Tanaka, Toshiko;
Pankow, James S.;
Vollenweider, Peter;
Lyssenko, Valeriya;
Bouatia-Naji, Nabila;
Dupuis, Josée;
Jackson, Anne U.;
Linda Kao, W. H.;
Man Li;
Glazer, Nicole L.;
Manning, Alisa K.;
Jian'an Luan;
Stringham, Heather M.;
Prokopenko, Inga;
Johnson, Toby;
Grarup, Niels;
Boesgaard, Trine W.

Publication type:

Article

Common variants in the GDF5-UQCC region are associated with variation in human height.

Published in:

Nature Genetics, 2008, v. 40, n. 2, p. 198, doi. 10.1038/ng.74

By:

Sanna, Serena;
Jackson, Anne U.;
Nagaraja, Ramaiah;
Willer, Cristen J.;
Wei-Min Chen;
Bonnycastle, Lori L.;
Haiqing Shen;
Timpson, Nicholas;
Lettre, Guillaume;
Usala, Gianluca;
Chines, Peter S.;
Stringham, Heather M.;
Scott, Laura J.;
Dei, Mariano;
Lai, Sandra;
Albai, Giuseppe;
Crisponi, Laura;
Naitza, Silvia;
Doheny, Kimberly F.;
Pugh, Elizabeth W.

Publication type:

Article

Newly identified loci that influence lipid concentrations and risk of coronary artery disease.

Published in:

Nature Genetics, 2008, v. 40, n. 2, p. 161, doi. 10.1038/ng.76

By:

Willer, Cristen J.;
Sanna, Serena;
Jackson, Anne U.;
Scuteri, Angelo;
Bonnycastle, Lori L.;
Clarke, Robert;
Heath, Simon C.;
Timpson, Nicholas J.;
Najjar, Samer S.;
Stringham, Heather M.;
Strait, James;
Duren, William L.;
Maschio, Andrea;
Busonero, Fabio;
Mulas, Antonella;
Albai, Giuseppe;
Swift, Amy J.;
Morken, Mario A.;
Narisu, Narisu;
Bennett, Derrick

Publication type:

Article

Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.

Published in:

2008

By:

Wei-Min Chen;
Erdos, Michael R.;
Jackson, Anne U.;
Saxena, Richa;
Sanna, Serena;
Silver, Kristi D.;
Timpson, Nicholas J.;
Hansen, Torben;
Orrù, Marco;
Piras, Maria Grazia;
Bonnycastle, Lori L.;
Willer, Cristen J.;
Lyssenko, Valeriya;
Haiqing Shen;
Kuusisto, Johanna;
Ebrahim, Shah;
Sestu, Natascia;
Duren, William L.;
Spada, Maria Cristina;
Stringham, Heather M.

Publication type:

journal article

Subset-Based Analysis Using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes.

Published in:

Human Heredity, 2019, v. 83, n. 6, p. 283, doi. 10.1159/000496867

By:

Yu, Youfei;
Xia, Lu;
Lee, Seunggeun;
Zhou, Xiang;
Stringham, Heather M.;
Boehnke, Michael;
Mukherjee, Bhramar

Publication type:

Article

Subset-Based Analysis Using Gene-Environment Interactions for Discovery of Genetic Associations across Multiple Studies or Phenotypes.

Published in:

Human Heredity, 2018, v. 83, n. 6, p. 283, doi. 10.1159/000496867

By:

Yu, Youfei;
Xia, Lu;
Lee, Seunggeun;
Zhou, Xiang;
Stringham, Heather M.;
Boehnke, Michael;
Mukherjee, Bhramar

Publication type:

Article

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion.

Published in:

Nature Genetics, 2013, v. 45, n. 2, p. 197, doi. 10.1038/ng.2507

By:

Huyghe, Jeroen R;
Jackson, Anne U;
Fogarty, Marie P;
Buchkovich, Martin L;
Stan?áková, Alena;
Stringham, Heather M;
Sim, Xueling;
Yang, Lingyao;
Fuchsberger, Christian;
Cederberg, Henna;
Chines, Peter S;
Teslovich, Tanya M;
Romm, Jane M;
Ling, Hua;
McMullen, Ivy;
Ingersoll, Roxann;
Pugh, Elizabeth W;
Doheny, Kimberly F;
Neale, Benjamin M;
Daly, Mark J

Publication type:

Article

Meta-analysis of gene-environment interaction exploiting gene-environment independence across multiple case-control studies.

Published in:

2017

By:

Estes, Jason P.;
Rice, John D.;
Li, Shi;
Stringham, Heather M.;
Boehnke, Michael;
Mukherjee, Bhramar

Publication type:

journal article

The genetic regulatory signature of type 2 diabetes in human skeletal muscle.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11764, doi. 10.1038/ncomms11764

By:

Scott, Laura J.;
Erdos, Michael R.;
Huyghe, Jeroen R.;
Welch, Ryan P.;
Beck, Andrew T.;
Wolford, Brooke N.;
Chines, Peter S.;
Didion, John P.;
Narisu, Narisu;
Stringham, Heather M.;
Taylor, D. Leland;
Jackson, Anne U.;
Vadlamudi, Swarooparani;
Bonnycastle, Lori L.;
Kinnunen, Leena;
Saramies, Jouko;
Sundvall, Jouko;
Albanus, Ricardo D'Oliveira;
Kiseleva, Anna;
Hensley, John

Publication type:

Article

A Partial Loss-of-Function Variant in Is Associated With Reduced Insulin-Mediated Glucose Uptake in Multiple Insulin-Sensitive Tissues: A Genotype-Based Callback Positron Emission Tomography Study.

Published in:

2018

By:

Latva-Rasku, Aino;
Honka, Miikka-Juhani;
Stancáková, Alena;
Koistinen, Heikki A.;
Kuusisto, Johanna;
Li Guan;
Manning, Alisa K.;
Stringham, Heather;
Gloyn, Anna L.;
Lindgren, Cecilia M.;
Collins, Francis S.;
Mohlke, Karen L.;
Scott, Laura J.;
Karjalainen, Tomi;
Nummenmaa, Lauri;
Boehnke, Michael;
Nuutila, Pirjo;
Laakso, Markku;
Stančáková, Alena;
Guan, Li

Publication type:

journal article

Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity.

Published in:

Diabetes, 2014, v. 63, n. 6, p. 2158, doi. 10.2337/db13-0949

By:

Dimas, Antigone S.;
Lagou, Vasiliki;
Barker, Adam;
Knowles, Joshua W.;
Mägi, Reedik;
Hivert, Marie-France;
Benazzo, Andrea;
Rybin, Denis;
Jackson, Anne U.;
Stringham, Heather M.;
Ci Song;
Fischer-Rosinsky, Antje;
Boesgaard, Trine Welløv;
Grarup, Niels;
Abbasi, Fahim A.;
Assimes, Themistocles L.;
Ke Hao;
Xia Yang;
Lecoeur, Cécile;
Barroso, Inês

Publication type:

Article

No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels.

Published in:

Diabetes, 2012, v. 61, n. 5, p. 1291, doi. 10.2337/db11-0973

By:

Scott, Robert A.;
Chu, Audrey Y.;
Grarup, Niels;
Manning, Alisa K.;
Hivert, Marie-France;
Shungin, Dmitry;
Tönjes, Anke;
Yesupriya, Ajay;
Barnes, Daniel;
Bouatia-Naji, Nabila;
Glazer, Nicole L.;
Jackson, Anne U.;
Kutalik, Zoltán;
Lagou, Vasiliki;
Marek, Diana;
Rasmussen-Torvik, Laura J.;
Stringham, Heather M.;
Tanaka, Toshiko;
Aadahl, Mette;
Arking, Dan E.

Publication type:

Article

Additive Effects of Genetic Variation in GCK and G6PC2 on Insulin Secretion and Fasting Glucose.

Published in:

Diabetes, 2009, v. 58, n. 12, p. 2946, doi. 10.2337/db09-0228

By:

Xia Li;
Yu-Hsiang Shu;
Xiang, Anny H.;
Trigo, Enrique;
Kuusisto, Johanna;
Hartiala, Jaana;
Swift, Amy J.;
Kawakubo, Miwa;
Stringham, Heather M.;
Bonnycastle, Lori L.;
Lawrence, Jean M.;
Laakso, Markku;
Allayee, Hooman;
Buchanan, Thomas A.;
Watanabe, Richard M.

Publication type:

Article

Screening of 134 Single Nucleotide Polymorphisms (SNPs) Previously Associated With Type 2 Diabetes Replicates Association With 12 SNPs in Nine Genes.

Published in:

Diabetes, 2007, v. 56, n. 1, p. 256, doi. 10.2337/db06-0461

By:

Willer, Cristen J.;
Bonnycastle, Lori L.;
Conneely, Karen N.;
Duren, William L.;
Jackson, Anne U.;
Scott, Laura J.;
Narisu, Narisu;
Chines, Peter S.;
Skol, Andrew;
Stringham, Heather M.;
Petrie, John;
Erdos, Michael R.;
Swift, Amy J.;
Enloe, Sareena T.;
Sprau, Andrew G.;
Smith, Eboni;
Tong, Maurine;
Doheny, Kimberly F.;
Pugh, Elizabeth W.;
Watanabe, Richard M.

Publication type:

Article

Association of Transcription Factor 7-Like 2 (TCF7L2) Variants With Type 2 Diabetes in a Finnish Sample.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2649, doi. 10.2337/db06-0341

By:

Scott, Laura J.;
Bonnycastle, Lori L.;
Willer, Cristen J.;
Sprau, Andrew G.;
Jackson, Anne U.;
Narisu, Narisu;
Duren, William L.;
Chines, Peter S.;
Stringham, Heather M.;
Erdos, Michael R.;
Valle, Timo T.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Mohlke, Karen L.;
Collins, Francis S.;
Boehnke, Michael

Publication type:

Article

Common Variants in Maturity-Onset Diabetes of the Young Genes Contribute to Risk of Type 2 Diabetes in Finns.

Published in:

Diabetes, 2006, v. 55, n. 9, p. 2534, doi. 10.2337/db06-0178

By:

Bonnycastle, Lori L.;
Willer, Cristen J.;
Conneely, Karen N.;
Jackson, Anne U.;
Burrill, Cecily P.;
Watanabe, Richard M.;
Chines, Peter S.;
Narisu, Narisu;
Scott, Laura J.;
Enloe, Sareena T.;
Swift, Amy J.;
Duren, William L.;
Stringham, Heather M.;
Erdos, Michael R.;
Riebow, Nancy L.;
Buchanan, Thomas A.;
Valle, Timo T.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Mohlke, Karen L.

Publication type:

Article

A large set of Finnish affected sibling pair families with type 2 diabetes suggests susceptibility loci on chromosomes 6, 11, and 14.

Published in:

2004

By:

Silander, Kaisa;
Scott, Laura J.;
Valle, Timo T.;
Mohlke, Karen L.;
Stringham, Heather M.;
Wiles, Kerry R.;
Duren, William L.;
Doheny, Kimberly F.;
Pugh, Elizabeth W.;
Chines, Peter;
Narisu, Narisu;
White, Peggy P.;
Fingerlin, Tasha E.;
Jackson, Anne U.;
Li, Chun;
Ghosh, Soumitra;
Magnuson, Victoria L.;
Colby, Kimberly;
Erdos, Michael R.;
Hill, Jason E.

Publication type:

journal article

Variation in three single nucleotide polymorphisms in the calpain-10 gene not associated with type 2 diabetes in a large Finnish cohort.

Published in:

2002

By:

Fingerlin, Tasha E.;
Erdos, Michael R.;
Watanabe, Richard M.;
Wiles, Kerry R.;
Stringham, Heather M.;
Mohlke, Karen L.;
Silander, Kaisa;
Valle, Timo T.;
Buchanan, Thomas A.;
Tuomilehto, Jaakko;
Bergman, Richard N.;
Boehnke, Michael;
Collins, Francis S.

Publication type:

journal article

Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.

Published in:

PLoS Genetics, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.pgen.1009019

By:

Spracklen, Cassandra N.;
Iyengar, Apoorva K.;
Vadlamudi, Swarooparani;
Raulerson, Chelsea K.;
Jackson, Anne U.;
Brotman, Sarah M.;
Wu, Ying;
Cannon, Maren E.;
Davis, James P.;
Crain, Aaron T.;
Currin, Kevin W.;
Perrin, Hannah J.;
Narisu, Narisu;
Stringham, Heather M.;
Fuchsberger, Christian;
Locke, Adam E.;
Welch, Ryan P.;
Kuusisto, Johanna K.;
Pajukanta, Päivi;
Scott, Laura J.

Publication type:

Article

Cell-Type Composition Affects Adipose Gene Expression Associations With Cardiometabolic Traits.

Published in:

Diabetes, 2023, v. 72, n. 11, p. 1707, doi. 10.2337/db23-0365

By:

Brotman, Sarah M.;
Oravilahti, Anniina;
Rosen, Jonathan D.;
Alvarez, Marcus;
Heinonen, Sini;
van der Kolk, Birgitta W.;
Fernandes Silva, Lilian;
Perrin, Hannah J.;
Vadlamudi, Swarooparani;
Pylant, Cortney;
Deochand, Sonia;
Basta, Patricia V.;
Valone, Jordan M.;
Narain, Morgan N.;
Stringham, Heather M.;
Boehnke, Michael;
Kuusisto, Johanna;
Love, Michael I.;
Pietiläinen, Kirsi H.;
Pajukanta, Päivi

Publication type:

Article

Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Published in:

PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007079

By:

Davis, James P.;
Huyghe, Jeroen R.;
Locke, Adam E.;
Jackson, Anne U.;
Sim, Xueling;
Stringham, Heather M.;
Teslovich, Tanya M.;
Welch, Ryan P.;
Fuchsberger, Christian;
Narisu, Narisu;
Chines, Peter S.;
Kangas, Antti J.;
Soininen, Pasi;
Ala-Korpela, Mika;
Kuusisto, Johanna;
Collins, Francis S.;
Laakso, Markku;
Boehnke, Michael;
Mohlke, Karen L.

Publication type:

Article

Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 24, p. 4161, doi. 10.1093/hmg/ddz263

By:

Wu, Ying;
Broadaway, K Alaine;
Raulerson, Chelsea K;
Scott, Laura J;
Pan, Calvin;
Ko, Arthur;
He, Aiqing;
Tilford, Charles;
Fuchsberger, Christian;
Locke, Adam E;
Stringham, Heather M;
Jackson, Anne U;
Narisu, Narisu;
Kuusisto, Johanna;
Pajukanta, Päivi;
Collins, Francis S;
Boehnke, Michael;
Laakso, Markku;
Lusis, Aldons J;
Civelek, Mete

Publication type:

Article

Identification of seven novel loci associated with amino acid levels using single-variant and gene-based tests in 8545 Finnish men from the METSIM study.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 9, p. 1664, doi. 10.1093/hmg/ddy067

By:

Teslovich, Tanya M.;
Kim, Daniel Seung;
Xianyong Yin;
Stančcáková, Alena;
Jackson, Anne U.;
Wielscher, Matthias;
Naj, Adam;
Perry, John R. B.;
Huyghe, Jeroen R.;
Stringham, Heather M.;
Davis, James P.;
Raulerson, Chelsea K.;
Welch, Ryan P.;
Fuchsberger, Christian;
Locke, Adam E.;
Xueling Sim;
Chines, Peter S.;
Narisu, Narisu;
Kangas, Antti J.;
Soininen, Pasi

Publication type:

Article