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Evaluating the Comparative Effectiveness of Two Diets in Pediatric Inflammatory Bowel Disease: A Study Protocol for a Series of N-of-1 Trials.
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- Healthcare (2227-9032), 2019, v. 7, n. 4, p. 129, doi. 10.3390/healthcare7040129
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- Article
Arabidopsis 56–Amino Acid Serine Palmitoyltransferase-Interacting Proteins Stimulate Sphingolipid Synthesis, Are Essential, and Affect Mycotoxin Sensitivity.
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- Plant Cell, 2013, v. 25, n. 11, p. 4627, doi. 10.1105/tpc.113.116145
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- Article
Steady-state pharmacokinetics of indinavir in cerebrospinal fluid and plasma among adults with human immunodeficiency virus type 1 infection<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2000, v. 68, n. 4, p. 367, doi. 10.1067/mcp.2000.109391
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- Article
Within these hyperporous walls: An examination of a rebundled online learning model of higher education.
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- Australasian Journal of Educational Technology, 2020, v. 36, n. 5, p. 85, doi. 10.14742/ajet.6061
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- Article
The Uthando Project: Dolls for the Children of KwaZulu-Natal.
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- Zero to Three, 2018, v. 38, n. 4, p. 79
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- Article
Legal Performance Good and Bad.
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- Law, Culture & the Humanities, 2008, v. 4, n. 2, p. 179, doi. 10.1177/1743872108091473
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- Article
Replens prevents preterm birth by decreasing type I interferon strengthening the cervical epithelial barrier.
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- American Journal of Reproductive Immunology, 2020, v. 83, n. 1, p. N.PAG, doi. 10.1111/aji.13192
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- Article
Effects of Omeprazole on Plasma Levels of Raltegravir.
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- Clinical Infectious Diseases, 2009, v. 48, n. 4, p. 489, doi. 10.1086/596503
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- Article
Atazanavir Modestly Increases Plasma Levels of Raltegravir in Healthy Subjects.
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- Clinical Infectious Diseases, 2008, v. 47, n. 1, p. 137, doi. 10.1086/588794
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- Article
Reactive oxygen species as signals that modulate plant stress responses and programmed cell death.
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- BioEssays, 2006, v. 28, n. 11, p. 1091, doi. 10.1002/bies.20493
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- Article
Activity of the Arabidopsis RD29A and RD29B promoter elements in soybean under water stress.
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- Planta: An International Journal of Plant Biology, 2013, v. 237, n. 1, p. 55, doi. 10.1007/s00425-012-1740-9
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- Article
Characterization of abiotic stress-responsive Arabidopsis thaliana RD29A and RD29B genes and evaluation of transgenes.
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- Planta: An International Journal of Plant Biology, 2011, v. 234, n. 1, p. 97, doi. 10.1007/s00425-011-1387-y
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- Article
A "Bridge over 'Chaos'": "De Jure Belli," "Paradise Lost," Terror, Sovereignty, Globalism, and the Modern Law of Nations.
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- 2005
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- Publication type:
- Literary Criticism
P3‐040: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE‐RESPONSE RESULTS FROM APECS, A PHASE 3 TRIAL IN PRODROMAL ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P941, doi. 10.1016/j.jalz.2019.06.3066
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- Article
P2‐002: AN INTEGRATED MECHANISTIC AMYLOID PATHWAY MODEL INFORMED BY CLINICAL BIOMARKER DATA FROM VERUBECESTAT AND OTHER BACE INHIBITORS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P571, doi. 10.1016/j.jalz.2019.06.1224
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- Publication type:
- Article
P1‐044: VERUBECESTAT DISEASE PROGRESSION MODELING FROM APECS, A PHASE 3 TRIAL IN PRODROMAL ALZHEIMER'S DISEASE: NO DOSE‐ AND EXPOSURE‐DEPENDENCY IN CLINICAL ENDPOINTS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P249, doi. 10.1016/j.jalz.2019.06.069
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- Publication type:
- Article
P3‐031: THE CRITICAL PATH FOR ALZHEIMER'S DISEASE: HIPPOCAMPAL VOLUME AS AN ENRICHMENT BIOMARKER IN TRIALS OF PATIENTS WITH MILD COGNITIVE IMPAIRMENT.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1076, doi. 10.1016/j.jalz.2018.06.1386
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- Publication type:
- Article
P1‐038: VERUBECESTAT PHARMACOKINETIC AND EXPOSURE‐RESPONSE RESULTS FROM EPOCH: A PHASE 3 TRIAL IN MILD‐TO‐MODERATE ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P281, doi. 10.1016/j.jalz.2018.06.039
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- Publication type:
- Article
ACUTE ADMINISTRATION OF A BACE INHIBITOR IN HEALTHY HUMANS RESULTS IN A SIGNIFICANT REDUCTION OF Aβ OLIGOMERS IN CEREBROSPINAL FLUID.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P574, doi. 10.1016/j.jalz.2017.07.192
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- Publication type:
- Article
SYSTEMS PHARMACOLOGY ANALYSIS OF THE Aβ OLIGOMER RESPONSE FOLLOWING BACE1 INHIBITION: EVIDENCE FOR SECOND-ORDER Aβ42 OLIGOMERIZATION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P281, doi. 10.1016/j.jalz.2017.06.175
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- Publication type:
- Article
RESILIENCE MECHANISM OF THE AMYLOID PRECURSOR PROTEIN (APP) PATHWAY REVEALED BY SYSTEMS PHARMACOLOGY MODELING FOLLOWING β- AND GAMMA-SECRETASE INHIBITION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P630, doi. 10.1016/j.jalz.2017.06.715
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- Publication type:
- Article
THE COALITION AGAINST MAJOR DISEASES: TOWARD U.S. FDA QUALIFICATION OF HIPPOCAMPAL VOLUME AS A BIOMARKER FOR ENRICHMENT IN CLINICAL TRIALS FOR PRE-DEMENTIA STAGES OF ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1259, doi. 10.1016/j.jalz.2017.06.1878
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- Publication type:
- Article
IS THE PERIPHERAL SINK HYPOTHESIS PHYSIOLOGICALLY FEASIBLE? EVIDENCE FROM MODEL-BASED ASSESSMENT OF THE AMYLOID PATHWAY.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P443, doi. 10.1016/j.jalz.2016.06.855
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- Publication type:
- Article
EVIDENCE FROM MODEL-BASED ASSESSMENTS OF COMPOUNDS TESTED IN COMPLETED CLINICAL TRIALS INDICATES THAT THE AMYLOID HYPOTHESIS HAS NOT BEEN ADEQUATELY TESTED.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P609, doi. 10.1016/j.jalz.2016.06.1209
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- Publication type:
- Article
Abeta oligomers as a pharmacodynamic biomarker of secretase therapy in Alzheimer's disease?
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P325, doi. 10.1016/j.jalz.2015.07.469
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- Publication type:
- Article
Development and application of a mathematical model of modulation of cerebrospinal fluid Aβ40 after treatment with gamma- and beta-secretase inhibitors
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- 2012
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- Publication type:
- Abstract
An integrated mechanistic model to interrelate CSF Aβ40, Aβ42, sAPPβ and sAPPα response to β- and γ-secretase inhibitors in rhesus monkey
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- 2012
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- Publication type:
- Abstract
Population pharmacokinetic modeling of the novel BACE inhibitor MK-8931 following single and multiple dose administration in healthy subjects
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- 2012
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- Publication type:
- Abstract
O4-03-02: The gamma secretase inhibitor MK-0752 acutely and significantly reduces CSF Abeta40 concentrations in humans
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- 2006
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- Publication type:
- Abstract
O4-03-02: The gamma secretase inhibitor MK-0752 acutely and significantly reduces CSF Abeta40 concentrations in humans
- Published in:
- 2006
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- Publication type:
- Abstract
A Plant DJ-1 Homolog Is Essential for Arabidopsis thaliana Chloroplast Development.
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- PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0023731
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- Publication type:
- Article
Block of Granulocyte-Macrophage Colony-Stimulating Factor Prevents Inflammation-Induced Preterm Birth in a Mouse Model for Parturition.
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- Reproductive Sciences, 2019, v. 26, n. 4, p. 551, doi. 10.1177/1933719118804420
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- Publication type:
- Article
Maternal genetic diseases: potential concerns for mother and baby.
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- Human Genetics, 2020, v. 139, n. 9, p. 1173, doi. 10.1007/s00439-019-02086-6
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- Article
Reviews.
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- Modern Law Review, 1999, v. 62, n. 3, p. 151, doi. 10.1111/1468-2230.t01-1-00198
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- Article
Population Pharmacokinetic Analysis of the Cathepsin K Inhibitor Odanacatib: Insights Into Intrinsic and Extrinsic Factor Effects on Exposure in Postmenopausal and Elderly Women.
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- Journal of Clinical Pharmacology, 2020, v. 60, n. 8, p. 1107, doi. 10.1002/jcph.1606
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- Article
A phase 1 pooled PK/PD analysis of bone resorption biomarkers for odanacatib, a Cathepsin K inhibitor.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 5, p. 473, doi. 10.1007/s10928-020-09699-9
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- Publication type:
- Article
Time dependent pharmacokinetics of pembrolizumab in patients with solid tumor and its correlation with best overall response.
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- Journal of Pharmacokinetics & Pharmacodynamics, 2017, v. 44, n. 5, p. 403, doi. 10.1007/s10928-017-9528-y
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- Publication type:
- Article
Pharmacokinetic-pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects.
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- British Journal of Clinical Pharmacology, 2013, v. 76, n. 6, p. 917, doi. 10.1111/bcp.12131
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- Publication type:
- Article
Odanacatib, a selective cathepsin K inhibitor to treat osteoporosis: safety, tolerability, pharmacokinetics and pharmacodynamics - results from single oral dose studies in healthy volunteers.
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- British Journal of Clinical Pharmacology, 2013, v. 75, n. 5, p. 1240, doi. 10.1111/j.1365-2125.2012.04471.x
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- Publication type:
- Article
Effect of raltegravir on estradiol and norgestimate plasma pharmacokinetics following oral contraceptive administration in healthy women.
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- British Journal of Clinical Pharmacology, 2011, v. 71, n. 4, p. 616, doi. 10.1111/j.1365-2125.2010.03885.x
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- Publication type:
- Article
An Investigation of Instability in Dried Blood Spot Samples for Pharmacokinetic Sampling in Phase 3 Trials of Verubecestat.
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- AAPS Journal, 2022, v. 24, n. 3, p. 1, doi. 10.1208/s12248-022-00683-4
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- Publication type:
- Article
A Model-Based Approach to Bridging Plasma and Dried Blood Spot Concentration Data for Phase 3 Verubecestat Trials.
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- AAPS Journal, 2022, v. 24, n. 3, p. 1, doi. 10.1208/s12248-022-00682-5
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- Publication type:
- Article
An Integrated Strategy for Implementation of Dried Blood Spots in Clinical Development Programs.
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- AAPS Journal, 2016, v. 18, n. 2, p. 519, doi. 10.1208/s12248-015-9860-3
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- Publication type:
- Article
A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design.
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- AAPS Journal, 2014, v. 16, n. 6, p. 1259, doi. 10.1208/s12248-014-9648-x
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- Publication type:
- Article
Simultaneous Pharmacokinetic Model for Rolofylline and both M1-trans and M1-cis Metabolites.
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- AAPS Journal, 2013, v. 15, n. 2, p. 498, doi. 10.1208/s12248-012-9443-5
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- Publication type:
- Article
Development of a Population Pharmacokinetic Model for Taranabant, a Cannibinoid-1 Receptor Inverse Agonist.
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- AAPS Journal, 2010, v. 12, n. 4, p. 537, doi. 10.1208/s12248-010-9212-2
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- Publication type:
- Article
Model-Based Decision Making in Early Clinical Development: Minimizing the Impact of a Blood Pressure Adverse Event.
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- AAPS Journal, 2009, v. 11, n. 1, p. 99, doi. 10.1208/s12248-009-9083-6
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- Publication type:
- Article
Molnupiravir: Mechanism of action, clinical, and translational science.
- Published in:
- CTS: Clinical & Translational Science, 2024, v. 17, n. 2, p. 1, doi. 10.1111/cts.13732
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- Publication type:
- Article
Is the vaginal or buccal route more effective when administering prostaglandins for cervical ripening at term?
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- OBG Management, 2019, v. 31, n. 7, p. 47
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- Publication type:
- Article
Comparison of Self-reported and Measured Pre-pregnancy Weight: Implications for Gestational Weight Gain Counseling.
- Published in:
- Maternal & Child Health Journal, 2017, v. 21, n. 7, p. 1469, doi. 10.1007/s10995-017-2266-3
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- Publication type:
- Article