Works by Stiles, Linsey

Results: 29

Age‐induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge.

Published in:

Aging Cell, 2020, v. 19, n. 11, p. 1, doi. 10.1111/acel.13166

By:

Moore, Timothy M.;
Zhou, Zhenqi;
Strumwasser, Alexander R.;
Cohn, Whitaker;
Lin, Amanda J.;
Cory, Kevin;
Whitney, Kate;
Ho, Theodore;
Ho, Timothy;
Lee, Joseph L.;
Rucker, Daniel H.;
Hoang, Austin N.;
Widjaja, Kevin;
Abrishami, Aaron D.;
Charugundla, Sarada;
Stiles, Linsey;
Whitelegge, Julian P.;
Turcotte, Lorraine P.;
Wanagat, Jonathan;
Hevener, Andrea L.

Publication type:

Article

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy.

Published in:

EMBO Journal, 2008, v. 27, n. 2, p. 433, doi. 10.1038/sj.emboj.7601963

By:

Twig, Gilad;
Elorza, Alvaro;
Molina, Anthony J. A.;
Mohamed, Hibo;
Wikstrom, Jakob D.;
Walzer, Gil;
Stiles, Linsey;
Haigh, Sarah E.;
Katz, Steve;
Las, Guy;
Alroy, Joseph;
Min Wu;
Py, Bénédicte F.;
Junying Yuan;
Deeney, Jude T.;
Corkey, Barbara E.;
Shirihai, Orian S.

Publication type:

Article

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers.

Published in:

Cancer & Metabolism, 2018, v. 6, n. 1, p. N.PAG, doi. 10.1186/s40170-018-0181-8

By:

Xu, Shili;
Catapang, Arthur;
Braas, Daniel;
Stiles, Linsey;
Doh, Hanna M.;
Lee, Jason T.;
Graeber, Thomas G.;
Damoiseaux, Robert;
Shirihai, Orian;
Herschman, Harvey R.

Publication type:

Article

Levocarnitine does not impair chemotherapy cytotoxicity against acute lymphoblastic leukemia.

Published in:

Leukemia & Lymphoma, 2020, v. 61, n. 2, p. 420, doi. 10.1080/10428194.2019.1666379

By:

Sea, Jessica L.;
Orgel, Etan;
Chen, Ting;
Paszkiewicz, Rebecca L.;
Krall, Abigail S.;
Oberley, Matthew J.;
Stiles, Linsey;
Mittelman, Steven D.

Publication type:

Article

Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA.

Published in:

EMBO Journal, 2023, v. 42, n. 11, p. 1, doi. 10.15252/embj.2022111901

By:

Ngo, Jennifer;
Choi, Dong Wook;
Stanley, Illana A;
Stiles, Linsey;
Molina, Anthony J A;
Chen, Pei‐Hsuan;
Lako, Ana;
Sung, Isabelle Chiao Han;
Goswami, Rishov;
Kim, Min‐young;
Miller, Nathanael;
Baghdasarian, Siyouneh;
Kim‐Vasquez, Doyeon;
Jones, Anthony E;
Roach, Brett;
Gutierrez, Vincent;
Erion, Karel;
Divakaruni, Ajit S;
Liesa, Marc;
Danial, Nika N

Publication type:

Article

Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies.

Published in:

EMBO Journal, 2023, v. 42, n. 10, p. 1, doi. 10.15252/embj.2022111699

By:

Acin‐Perez, Rebeca;
Benincá, Cristiane;
Fernandez del Rio, Lucia;
Shu, Cynthia;
Baghdasarian, Siyouneh;
Zanette, Vanessa;
Gerle, Christoph;
Jiko, Chimari;
Khairallah, Ramzi;
Khan, Shaharyar;
Rincon Fernandez Pacheco, David;
Shabane, Byourak;
Erion, Karel;
Masand, Ruchi;
Dugar, Sundeep;
Ghenoiu, Cristina;
Schreiner, George;
Stiles, Linsey;
Liesa, Marc;
Shirihai, Orian S

Publication type:

Article

A novel approach to measure mitochondrial respiration in frozen biological samples.

Published in:

EMBO Journal, 2020, v. 39, n. 13, p. 1, doi. 10.15252/embj.2019104073

By:

Acin‐Perez, Rebeca;
Benador, Ilan Y;
Petcherski, Anton;
Veliova, Michaela;
Benavides, Gloria A;
Lagarrigue, Sylviane;
Caudal, Arianne;
Vergnes, Laurent;
Murphy, Anne N;
Karamanlidis, Georgios;
Tian, Rong;
Reue, Karen;
Wanagat, Jonathan;
Sacks, Harold;
Amati, Francesca;
Darley‐Usmar, Victor M;
Liesa, Marc;
Divakaruni, Ajit S;
Stiles, Linsey;
Shirihai, Orian S

Publication type:

Article

Calculation of ATP production rates using the Seahorse XF Analyzer.

Published in:

EMBO Reports, 2023, v. 24, n. 10, p. 1, doi. 10.15252/embr.202256380

By:

Desousa, Brandon R;
Kim, Kristen KO;
Jones, Anthony E;
Ball, Andréa B;
Hsieh, Wei Y;
Swain, Pamela;
Morrow, Danielle H;
Brownstein, Alexandra J;
Ferrick, David A;
Shirihai, Orian S;
Neilson, Andrew;
Nathanson, David A;
Rogers, George W;
Dranka, Brian P;
Murphy, Anne N;
Affourtit, Charles;
Bensinger, Steven J;
Stiles, Linsey;
Romero, Natalia;
Divakaruni, Ajit S

Publication type:

Article

Blocking mitochondrial pyruvate import in brown adipocytes induces energy wasting via lipid cycling.

Published in:

EMBO Reports, 2020, v. 21, n. 12, p. 1, doi. 10.15252/embr.201949634

By:

Veliova, Michaela;
Ferreira, Caroline M;
Benador, Ilan Y;
Jones, Anthony E;
Mahdaviani, Kiana;
Brownstein, Alexandra J;
Desousa, Brandon R;
Acín‐Pérez, Rebeca;
Petcherski, Anton;
Assali, Essam A;
Stiles, Linsey;
Divakaruni, Ajit S;
Prentki, Marc;
Corkey, Barbara E;
Liesa, Marc;
Oliveira, Marcus F;
Shirihai, Orian S

Publication type:

Article

Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.

Published in:

EMBO Reports, 2017, v. 18, n. 7, p. 1123, doi. 10.15252/embr.201643827

By:

Mahdaviani, Kiana;
Benador, Ilan Y;
Su, Shi;
Gharakhanian, Raffi A;
Stiles, Linsey;
Trudeau, Kyle M;
Cardamone, Maria;
Enríquez‐Zarralanga, Violeta;
Ritou, Eleni;
Aprahamian, Tamar;
Oliveira, Marcus F;
Corkey, Barbara E;
Perissi, Valentina;
Liesa, Marc;
Shirihai, Orian S

Publication type:

Article

Pro-inflammatory macrophage activation does not require inhibition of oxidative phosphorylation.

Published in:

EMBO Reports, 2025, v. 26, n. 4, p. 982, doi. 10.1038/s44319-024-00351-y

By:

Ball, Andréa B;
Jones, Anthony E;
Nguyễn, Kaitlyn B;
Rios, Amy;
Marx, Nico;
Hsieh, Wei Yuan;
Yang, Krista;
Desousa, Brandon R;
Kim, Kristen K O;
Veliova, Michaela;
del Mundo, Zena Marie;
Shirihai, Orian S;
Benincá, Cristiane;
Stiles, Linsey;
Bensinger, Steven J;
Divakaruni, Ajit S

Publication type:

Article

Effect of voluntary exercise upon the metabolic syndrome and gut microbiome composition in mice.

Published in:

Physiological Reports, 2021, v. 9, n. 21, p. 1, doi. 10.14814/phy2.15068

By:

Moore, Timothy M.;
Terrazas, Anthony;
Strumwasser, Alexander R.;
Lin, Amanda J.;
Zhu, Xiaopeng;
Anand, Akshay T. S.;
Nguyen, Christina Q.;
Stiles, Linsey;
Norheim, Frode;
Lang, Jennifer M.;
Hui, Simon T.;
Turcotte, Lorraine P.;
Zhou, Zhenqi

Publication type:

Article

Sex differences in the neuronal transcriptome and synaptic mitochondrial function in the cerebral cortex of a multiple sclerosis model.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1268411

By:

Noriko Itoh;
Yuichiro Itoh;
Stiles, Linsey;
Voskuhl, Rhonda

Publication type:

Article

Mitochondrial Proton Leak Regulated by Cyclophilin D Elevates Insulin Secretion in Islets at Nonstimulatory Glucose Levels.

Published in:

2020

By:

Taddeo, Evan P.;
Alsabeeh, Nour;
Baghdasarian, Siyouneh;
Wikstrom, Jakob D.;
Ritou, Eleni;
Sereda, Samuel;
Erion, Karel;
Jin Li;
Stiles, Linsey;
Abdulla, Muhamad;
Swanson, Zachary;
Wilhelm, Joshua J.;
Bellin, Melena D.;
Kibbey, Richard G.;
Liesa, Marc;
Shirihai, Orian S.;
Li, Jin

Publication type:

journal article

Dapagliflozin prevents abdominal visceral and subcutaneous adipose tissue dysfunction in the insulin‐resistant canine model.

Published in:

Obesity (19307381), 2023, v. 31, n. 7, p. 1798, doi. 10.1002/oby.23771

By:

Kabir, Morvarid;
Bergman, Richard N.;
Porter, Jay;
Stefanovski, Darko;
Paszkiewicz, Rebecca L.;
Piccinini, Francesca;
Woolcott, Orison O.;
Yang, HsiuChiung;
Gopaul, V. Sashi;
Stiles, Linsey;
Kolka, Cathryn M.

Publication type:

Article

ABCB10 exports mitochondrial biliverdin, driving metabolic maladaptation in obesity.

Published in:

Science Translational Medicine, 2021, v. 13, n. 594, p. 1, doi. 10.1126/scitranslmed.abd1869

By:

Shum, Michael;
Shintre, Chitra A.;
Althoff, Thorsten;
Gutierrez, Vincent;
Segawa, Mayuko;
Saxberg, Alexandra D.;
Martinez, Melissa;
Adamson, Roslin;
Young, Margaret R.;
Faust, Belinda;
Gharakhanian, Raffi;
Su, Shi;
Chella Krishnan, Karthickeyan;
Mahdaviani, Kiana;
Veliova, Michaela;
Wolf, Dane M.;
Ngo, Jennifer;
Nocito, Laura;
Stiles, Linsey;
Abramson, Jeff

Publication type:

Article

Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives.

Published in:

Life (2075-1729), 2021, v. 11, n. 9, p. 949, doi. 10.3390/life11090949

By:

Acin-Perez, Rebeca;
Benincá, Cristiane;
Shabane, Byourak;
Shirihai, Orian S.;
Stiles, Linsey

Publication type:

Article

Mitochondrial Dysfunction Is an Early Consequence of Partial or Complete Dystrophin Loss in mdx Mice.

Published in:

Frontiers in Physiology, 2020, v. 11, p. 1, doi. 10.3389/fphys.2020.00690

By:

Moore, Timothy M.;
Lin, Amanda J.;
Strumwasser, Alexander R.;
Cory, Kevin;
Whitney, Kate;
Ho, Theodore;
Ho, Timothy;
Lee, Joseph L.;
Rucker, Daniel H.;
Nguyen, Christina Q.;
Yackly, Aidan;
Mahata, Sushil K.;
Wanagat, Jonathan;
Stiles, Linsey;
Turcotte, Lorraine P.;
Crosbie, Rachelle H.;
Zhou, Zhenqi

Publication type:

Article

A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0033023

By:

Wikstrom, Jakob D.;
Sereda, Samuel B.;
Stiles, Linsey;
Elorza, Alvaro;
Allister, Emma M.;
Neilson, Andy;
Ferrick, David A.;
Wheeler, Michael B.;
Shirihai, Orian S.

Publication type:

Article

P2‐001: MITOCHONDRIAL ENERGY FROM OMEGA‐3 FOR AMYLOID‐BETA PHAGOCYTOSIS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P571, doi. 10.1016/j.jalz.2019.06.4960

By:

Fiala, Milan;
Pellegrini, Matteo A.;
Stiles, Linsey

Publication type:

Article

Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines.

Published in:

Cells (2073-4409), 2025, v. 14, n. 2, p. 137, doi. 10.3390/cells14020137

By:

Pohl, Katherine A.;
Zhang, Xiangmei;
Ji, Johnny Jeonghyun;
Stiles, Linsey;
Sadun, Alfredo A.;
Yang, Xian-Jie

Publication type:

Article

Skin Corticotropin-Releasing Hormone Receptor Expression in Psoriasis.

Published in:

2007

By:

Tagen, Michael;
Stiles, Linsey;
Kalogeromitros, Demetrios;
Gregoriou, Stamatios;
Kempuraj, Duraisamy;
Makris, Michael;
Donelan, Jill;
Vasiadi, Magdalini;
Staurianeas, Nikolaos G.;
Theoharides, Theoharis C.

Publication type:

Letter

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors.

Published in:

Toxicological Sciences, 2017, v. 155, n. 1, p. 61, doi. 10.1093/toxsci/kfw193

By:

Woodhead, Jeffrey L.;
Brock, William J.;
Roth, Sharin E.;
Shoaf, Susan E.;
Brouwer, Kim L. R.;
Church, Rachel;
Grammatopoulos, Tom N.;
Stiles, Linsey;
Siler, Scott Q.;
Howell, Brett A.;
Mosedale, Merrie;
Watkins, Paul B.;
Shoda, Lisl K. M.

Publication type:

Article

TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice.

Published in:

Brain Sciences (2076-3425), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/brainsci12070900

By:

Desai, Mina;
Stiles, Linsey;
Torsoni, Adriana S.;
Torsoni, Marcio A.;
Shirihai, Orian S.;
Ross, Michael G.

Publication type:

Article

Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24232-3

By:

Li, Jiwen;
Pan, Lin;
Pembroke, William G.;
Rexach, Jessica E.;
Godoy, Marlesa I.;
Condro, Michael C.;
Alvarado, Alvaro G.;
Harteni, Mineli;
Chen, Yen-Wei;
Stiles, Linsey;
Chen, Angela Y.;
Wanner, Ina B.;
Yang, Xia;
Goldman, Steven A.;
Geschwind, Daniel H.;
Kornblum, Harley I.;
Zhang, Ye

Publication type:

Article

Sex‐Specific Genetic Regulation of Adipose Mitochondria and Their Relationship to Metabolic Syndrome.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.05287

By:

Chella Krishnan, Karthickeyan;
Vergnes, Laurent;
Acín‐Pérez, Rebeca;
Stiles, Linsey;
Ma, Lijiang;
Reue, Karen;
Björkegren, Johan;
Laakso, Markku;
Lusis, Aldons

Publication type:

Article

Omega‐3 fatty acids increase OXPHOS energy for immune therapy of Alzheimer disease patients.

Published in:

FASEB Journal, 2020, v. 34, n. 8, p. 9982, doi. 10.1096/fj.202000669RR

By:

Lau, Yik Chai Charles;
Ding, Jessica Aliyah;
Simental, Aracely;
Mirzoyan, Hayk;
Lee, William;
Diamante, Graciel;
Cely, Ingrid;
Tran, Michelle;
Morselli, Marco;
Dang, Johnny;
Kaczor‐Urbanowicz, Karolina Elżbieta;
Sayre, James;
Stiles, Linsey;
Yang, Xia;
Pellegrini, Matteo;
Fiala, Milan

Publication type:

Article

Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

Published in:

2009

By:

Molina AJ;
Wikstrom JD;
Stiles L;
Las G;
Mohamed H;
Elorza A;
Walzer G;
Twig G;
Katz S;
Corkey BE;
Shirihai OS;
Molina, Anthony J A;
Wikstrom, Jakob D;
Stiles, Linsey;
Las, Guy;
Mohamed, Hibo;
Elorza, Alvaro;
Walzer, Gil;
Twig, Gilad;
Katz, Steve

Publication type:

journal article

Mitochondrial Networking Protects β-Cells From Nutrient-Induced Apoptosis.

Published in:

Diabetes, 2009, v. 58, n. 10, p. 2303, doi. 10.2337/db07-1781

By:

Molina, Anthony J. A.;
Wikstrom, Jakob D.;
Stiles, Linsey;
Las, Guy;
Mohamed, Hibo;
Elorza, Alvaro;
Walzer, Gil;
Twig, Gilad;
Katz, Steve;
Corkey, Barbara E.;
Shirihaix, Orian S.

Publication type:

Article