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Pharmacodynamics and Cancer: Practical Aspects of Dose Intensity for Pharmacists.
- Published in:
- Journal of Pharmacy Practice, 1991, v. 4, n. 1, p. 11, doi. 10.1177/089719009100400103
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- Publication type:
- Article
Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice.
- Published in:
- Pharmaceutical Research, 2023, v. 40, n. 11, p. 2555, doi. 10.1007/s11095-023-03554-5
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- Publication type:
- Article
Corrigendum: Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss.
- Published in:
- Nature Genetics, 2015, v. 47, n. 4, p. 423, doi. 10.1038/ng0415-423
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- Publication type:
- Article
Common variants in ACYP2 influence susceptibility to cisplatin-induced hearing loss.
- Published in:
- Nature Genetics, 2015, v. 47, n. 3, p. 263, doi. 10.1038/ng.3217
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- Publication type:
- Article
Pharmacokinetic Modeling of an Induction Regimen for In Vivo Combined Testing of Novel Drugs against Pediatric Acute Lymphoblastic Leukemia Xenografts.
- Published in:
- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033894
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- Publication type:
- Article
Relation of systemic exposure to unbound etoposide and hematologic toxicity.
- Published in:
- Clinical Pharmacology & Therapeutics, 1991, v. 50, n. 4, p. 385, doi. 10.1038/clpt.1991.155
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- Publication type:
- Article
Coadministration of naproxen and low-dose methotrexate in patients with rheumatoid arthritis.
- Published in:
- Clinical Pharmacology & Therapeutics, 1990, v. 47, n. 4, p. 540, doi. 10.1038/clpt.1990.69
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- Publication type:
- Article
Altered protein binding of etoposide in patients with cancer.
- Published in:
- Clinical Pharmacology & Therapeutics, 1989, v. 45, n. 1, p. 49, doi. 10.1038/clpt.1989.8
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- Publication type:
- Article
Schedule-dependent Efficacy of Camptothecins in Models of Human Cancer<sup>a</sup>.
- Published in:
- Annals of the New York Academy of Sciences, 1996, v. 803, n. 1, p. 188, doi. 10.1111/j.1749-6632.1996.tb26388.x
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- Publication type:
- Article
Relationship between topotecan systemic exposure and tumor response in human neuroblastoma xenografts.
- Published in:
- 1998
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- Publication type:
- journal article
Entinostat as a combinatorial therapeutic for rhabdomyosarcoma.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66545-5
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- Publication type:
- Article
Pharmacokinetic basis for dosing high‐dose methotrexate in infants and young children with malignant brain tumours.
- Published in:
- British Journal of Clinical Pharmacology, 2020, v. 86, n. 2, p. 362, doi. 10.1111/bcp.14160
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- Publication type:
- Article
Disposition of high-dose methotrexate in an obese cancer patient.
- Published in:
- 1991
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- Publication type:
- journal article
Development and Validation of a Sensitive and Specific LC-MS/MS Method for IWR-1-Endo, a Wnt Signaling Inhibitor: Application to a Cerebral Microdialysis Study.
- Published in:
- Molecules, 2022, v. 27, n. 17, p. 5448, doi. 10.3390/molecules27175448
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- Publication type:
- Article
Phase II evaluation of sunitinib in the treatment of recurrent or refractory high-grade glioma or ependymoma in children: a children's Oncology Group Study ACNS1021.
- Published in:
- Cancer Medicine, 2016, v. 5, n. 7, p. 1416, doi. 10.1002/cam4.713
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- Publication type:
- Article
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.
- Published in:
- Neuro-Oncology, 2021, v. 23, n. 10, p. 1777, doi. 10.1093/neuonc/noab047
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- Publication type:
- Article
LGG-02. A PHASE II PROSPECTIVE TRIAL OF SELUMETINIB IN CHILDREN WITH RECURRENT/PROGRESSIVE PEDIATRIC LOW-GRADE GLIOMA (PLGG) WITH A FOCUS UPON OPTIC PATHWAY/HYPOTHALAMIC TUMORS AND VISUAL ACUITY OUTCOMES: A PEDIATRIC BRAIN TUMOR CONSORTIUM (PBTC) STUDY, PBTC-029B
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii98, doi. 10.1093/neuonc/noz036.145
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- Publication type:
- Article
A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.
- Published in:
- Neuro-Oncology, 2017, v. 19, n. 8, p. 1135, doi. 10.1093/neuonc/now282
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- Publication type:
- Article
Phase I study of 5-fluorouracil in children and young adults with recurrent ependymoma.
- Published in:
- Neuro-Oncology, 2015, v. 17, n. 12, p. 1620, doi. 10.1093/neuonc/nov181
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- Publication type:
- Article
Evaluation of amifostine for protection against cisplatin-induced serious hearing loss in children treated for average-risk or high-risk medulloblastoma.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. 6, p. 848, doi. 10.1093/neuonc/not241
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- Publication type:
- Article
Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: A report from the Children's Oncology Group.
- Published in:
- Neuro-Oncology, 2013, v. 15, n. 10, p. 1438, doi. 10.1093/neuonc/not058
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- Publication type:
- Article
A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: A report from the Pediatric Brain Tumor Consortium.
- Published in:
- Neuro-Oncology, 2011, v. 13, n. 3, p. 290, doi. 10.1093/neuonc/noq199
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- Publication type:
- Article
Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with medulloblastoma.
- Published in:
- Neuro-Oncology, 2006, v. 8, n. 2, p. 89, doi. 10.1215/15228517-2005-004
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- Publication type:
- Article
Review of microdialysis in brain tumors, from concept to application: First Annual Carolyn Frye-Halloran Symposium.
- Published in:
- Neuro-Oncology, 2004, v. 6, n. 1, p. 65, doi. 10.1215/S1152851703000103
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- Publication type:
- Article
Phase II Study of Topotecan in Combination With Dexamethasone, Asparaginase, and Vincristine in Pediatric Patients With Acute Lymphoblastic Leukemia in First Relapse.
- Published in:
- Cancer (0008543X), 2008, v. 112, n. 9, p. 1983, doi. 10.1002/cncr.23395
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- Publication type:
- Article
Effect of intrapatient dosage escalation of irinotecan on its pharmacokinetics in pediatric patients who have high-grade gliomas and receive enzyme-inducing anticonvulsant therapy.
- Published in:
- 2003
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- Publication type:
- journal article
Effect of intrapatient dosage escalation of irinotecan on its pharmacokinetics in pediatric patients who have high-grade gliomas and receive enzyme-inducing anticonvulsant therapy.
- Published in:
- Cancer (0008543X), 2003, v. 97, p. 2374
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- Publication type:
- Article
Fusion Oncoproteins in Childhood Cancers: Potential Role in Targeted Therapy.
- Published in:
- Journal of Pediatric Pharmacology & Therapeutics, 2021, v. 26, n. 6, p. 541, doi. 10.5863/1551-6776-26.6.541
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- Publication type:
- Article
Developing Therapy for Every Kid With Cancer – Summary of a Scientific Session at the 2023 ASCPT Meeting.
- Published in:
- Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 2, p. 185, doi. 10.1002/cpt.3101
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- Publication type:
- Article
The RACE to Develop New Targeted Therapies for Children With CNS Tumors.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 434, doi. 10.1002/cpt.1937
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- Publication type:
- Article
Development of Molecularly Targeted Therapies to Treat Pediatric Malignancies.
- Published in:
- Clinical Pharmacology & Therapeutics, 2017, v. 102, n. 5, p. 752, doi. 10.1002/cpt.785
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- Publication type:
- Article
CNS Penetration of Cyclophosphamide and Metabolites in Mice Bearing Group 3 Medulloblastoma and Non-Tumor Bearing Mice.
- Published in:
- Journal of Pharmacy & Pharmaceutical Sciences, 2019, v. 22, p. 612
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- Publication type:
- Article
An LC/ESI–MS/MS method to quantify the PI3K inhibitor GDC‐0084 in human plasma and cerebrospinal fluid: Validation and clinical application.
- Published in:
- Biomedical Chromatography, 2020, v. 34, n. 1, p. N.PAG, doi. 10.1002/bmc.4697
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- Publication type:
- Article
Determination of dopamine, serotonin, and their metabolites in pediatric cerebrospinal fluid by isocratic high performance liquid chromatography coupled with electrochemical detection.
- Published in:
- Biomedical Chromatography, 2010, v. 24, n. 6, p. 626, doi. 10.1002/bmc.1338
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- Publication type:
- Article
Application of a highly specific and sensitive fluorescent HPLC method for topotecan lactone in whole blood.
- Published in:
- Biomedical Chromatography, 2009, v. 23, n. 7, p. 707, doi. 10.1002/bmc.1173
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- Publication type:
- Article
Population pharmacokinetics of crenolanib in children and young adults with brain tumors.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 4, p. 459, doi. 10.1007/s00280-022-04412-8
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- Publication type:
- Article
Population pharmacokinetic analysis of crizotinib in children with progressive/recurrent high-grade and diffuse intrinsic pontine gliomas.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Correction to: Pharmacokinetics and safety of erlotinib and its metabolite OSI-420 in infants and children with primary brain tumors.
- Published in:
- 2020
- By:
- Publication type:
- corrected article
Pharmacokinetics and safety of erlotinib and its metabolite OSI-420 in infants and children with primary brain tumors.
- Published in:
- 2019
- By:
- Publication type:
- journal article
CNS penetration of the CDK4/6 inhibitor ribociclib in non-tumor bearing mice and mice bearing pediatric brain tumors.
- Published in:
- 2019
- By:
- Publication type:
- journal article
A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its application for dose specification.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Response to: comment on "Delayed methotrexate excretion in infants and young children with primary central nervous system tumors and postoperative fluid collections".
- Published in:
- 2015
- By:
- Publication type:
- commentary
In vitro evaluation of the effects of gefitinib on the modulation of cytotoxic activity of selected anticancer agents in a panel of human ovarian cancer cell lines.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 1, p. 51, doi. 10.1007/s00280-007-0572-y
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- Publication type:
- Article
Development and validation of limited sampling models for topotecan lactone pharmacokinetic studies in children.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 4, p. 475, doi. 10.1007/s00280-005-0062-z
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- Publication type:
- Article
Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Interferon-gamma pharmacokinetics and pharmacodynamics in patients with colorectal cancer.
- Published in:
- Cancer Chemotherapy & Pharmacology, 2004, v. 53, n. 3, p. 253
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- Publication type:
- Article
Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors.
- Published in:
- 2003
- By:
- Publication type:
- journal article
Model‐based evaluation of image‐guided fractionated whole‐brain radiation therapy in pediatric diffuse intrinsic pontine glioma xenografts.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 6, p. 599, doi. 10.1002/psp4.12627
- By:
- Publication type:
- Article
Pharmacokinetic Properties of Anticancer Agents for the Treatment of Central Nervous System Tumors: Update of the Literature.
- Published in:
- 2016
- By:
- Publication type:
- journal article