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Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
Published in:
2007
By:
- Salvati, Erica;
- Leonetti, Carlo;
- Rizzo, Angela;
- Scarsella, Marco;
- Mottolese, Marcella;
- Galati, Rossella;
- Sperduti, Isabella;
- Stevens, Malcolm F. G.;
- d'Incalci, Maurizio;
- Blasco, Maria;
- Chiorino, Giovanna;
- Bauwens, Serge;
- Horard, Béatrice;
- Gilson, Eric;
- Stoppacciaro, Antonella;
- Zupi, Gabriella;
- Biroccio, Annamaria;
- Horard, Béatrice
Publication type:
journal article
RHPS4 G-Quadruplex Ligand Induces Anti-Proliferative Effects in Brain Tumor Cells.
Published in:
PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0086187
By:
- Lagah, Sunil;
- Tan, I-Li;
- Radhakrishnan, Priya;
- Hirst, Robert A.;
- Ward, Jennifer H.;
- O’Callaghan, Chris;
- Smith, Stuart J.;
- Stevens, Malcolm F. G.;
- Grundy, Richard G.;
- Rahman, Ruman
Publication type:
Article
On and off-target effects of telomere uncapping G-quadruplex selective ligands based on pentacyclic acridinium salts.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2013, v. 32, n. 1, p. 1, doi. 10.1186/1756-9966-32-68
By:
- Sara Iachettini;
- Stevens, Malcolm F. G.;
- Frigerio, Mark;
- Hummersone, Marc G.;
- Hutchinson, Ian;
- Garner, Thomas P.;
- Searle, Mark S.;
- Wilson, David W.;
- Manoj Munde;
- Rupesh Nanjunda;
- D'Angelo, Carmen;
- Zizza, Pasquale;
- Rizzo, Angela;
- Cingolani, Chiara;
- De Cicco, Federica;
- Porru, Manuela;
- D'Incalci, Maurizio;
- Leonetti, Carlo;
- Biroccio, Annamaria;
- Salvati, Erica
Publication type:
Article
The antitumour activity of 2‐(4‐amino‐3‐methylphenyl)‐5‐fluorobenzothiazole in human gastric cancer models is mediated by AhR signalling.
Published in:
Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 2, p. 1750, doi. 10.1111/jcmm.14869
By:
- Wang, Yuling;
- Liu, Ying;
- Tang, Tao;
- Luo, Ying;
- Stevens, Malcolm F. G.;
- Cheng, Xi;
- Yang, Yan;
- Shi, Dongfang;
- Zhang, Jihong;
- Bradshaw, Tracey D.
Publication type:
Article
Temozolomide analog PMX 465 downregulates MGMT expression in HCT116 colorectal carcinoma cells.
Published in:
Journal of Cellular Biochemistry, 2018, v. 119, n. 7, p. 5350, doi. 10.1002/jcb.26674
By:
- Yang, Zhikuan;
- Wei, Danping;
- Liu, Feifei;
- Liu, Jing;
- Wu, Xiaoming;
- Stevens, Malcolm F. G.;
- Bradshaw, Tracey D.;
- Luo, Ying;
- Zhang, Jihong
Publication type:
Article
C8-Substituted Imidazotetrazine Analogs Overcome Temozolomide Resistance by Inducing DNA Adducts and DNA Damage.
Published in:
Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00485
By:
- Yang, Zhikuan;
- Wei, Danping;
- Dai, Xiaoli;
- Stevens, Malcolm F. G.;
- Bradshaw, Tracey D.;
- Luo, Ying;
- Zhang, Jihong
Publication type:
Article
Recognition and Stabilization of Quadruplex DNA by a Potent New Telomerase Inhibitor: NMR Studies of the 2:1 Complex of a Pentacyclic Methylacridinium Cation with d(TTAGGGT).
Published in:
Angewandte Chemie International Edition, 2001, v. 40, n. 24, p. 4749, doi. 10.1002/1521-3773(20011217)40:24<4749::AID-ANIE4749>3.0.CO;2-I
By:
- Gavathiotis, Evripidis;
- Heald, Robert A.;
- Stevens, Malcolm F. G.;
- Searle, Mark S.
Publication type:
Article
Acquired Resistance to Temozolomide in Glioma Cell Lines: Molecular Mechanisms and Potential Translational Applications.
Published in:
Oncology, 2010, v. 78, n. 2, p. 103, doi. 10.1159/000306139
By:
- Jihong Zhang;
- Stevens, Malcolm F. G.;
- Laughton, Charles A.;
- Madhusudan, Srinivasan;
- Bradshaw, Tracey D.
Publication type:
Article
Modulation of the acidity of the 8-carboxamide group in the temozolomide family of antitumor imidazo[5,1-d][1,2,3,5]tetrazines.
Published in:
ARKIVOC: Online Journal of Organic Chemistry, 2020, v. 2020, p. 36, doi. 10.24820/ark.5550190.p011.182
By:
- Summers, Helen S.;
- Foreiter, Magdalena B.;
- Lewis, William;
- Moody, Christopher J.;
- Bradshaw, Tracey D.;
- Stevens, Malcolm F. G.
Publication type:
Article

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