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Improving enzyme functional annotation by integrating in vitro and in silico approaches: The example of histidinol phosphate phosphatases.
- Published in:
- Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 2, p. 1, doi. 10.1002/pro.4899
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- Publication type:
- Article
Experimental and computational analysis of the ancestry of an evolutionary young enzyme from histidine biosynthesis.
- Published in:
- Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 1, p. 1, doi. 10.1002/pro.4536
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- Publication type:
- Article
Molecular basis for the allosteric activation mechanism of the heterodimeric imidazole glycerol phosphate synthase complex.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22968-6
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- Publication type:
- Article
Towards Photochromic Azobenzene‐Based Inhibitors for Tryptophan Synthase.
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- Chemistry - A European Journal, 2021, v. 27, n. 7, p. 2439, doi. 10.1002/chem.202004061
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- Publication type:
- Article
Generation of a Stand‐Alone Tryptophan Synthase α‐Subunit by Mimicking an Evolutionary Blueprint.
- Published in:
- ChemBioChem, 2019, v. 20, n. 21, p. 2747, doi. 10.1002/cbic.201900323
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- Publication type:
- Article
Light-Regulation of Tryptophan Synthase by Combining Protein Design and Enzymology.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 20, p. 5106, doi. 10.3390/ijms20205106
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- Publication type:
- Article
Prediction of quaternary structure by analysis of hot spot residues in protein‐protein interfaces: the case of anthranilate phosphoribosyltransferases.
- Published in:
- Proteins, 2019, v. 87, n. 10, p. 815, doi. 10.1002/prot.25744
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- Publication type:
- Article
Mapping key amino acid residues for the epimerase efficiency and stereospecificity of the sex pheromone biosynthetic short-chain dehydrogenases/reductases of Nasonia.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37200-7
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- Publication type:
- Article
Artificial Light Regulation of an Allosteric Bienzyme Complex by a Photosensitive Ligand.
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- ChemBioChem, 2018, v. 19, n. 16, p. 1750, doi. 10.1002/cbic.201800219
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- Publication type:
- Article
Rosetta:MSF: a modular framework for multi-state computational protein design.
- Published in:
- 2017
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- Publication type:
- Product Review
Combining ancestral sequence reconstruction with protein design to identify an interface hotspot in a key metabolic enzyme complex.
- Published in:
- Proteins, 2017, v. 85, n. 2, p. 312, doi. 10.1002/prot.25225
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- Publication type:
- Article
Highlight issue: protein design.
- Published in:
- Biological Chemistry, 2017, v. 398, n. 1, p. 1, doi. 10.1515/hsz-2016-0322
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- Publication type:
- Article
Epimerisation of chiral hydroxylactones by short-chain dehydrogenases/reductases accounts for sex pheromone evolution in Nasonia.
- Published in:
- Scientific Reports, 2016, p. 34697, doi. 10.1038/srep34697
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- Publication type:
- Article
Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation.
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- PLoS Genetics, 2016, v. 12, n. 1, p. 1, doi. 10.1371/journal.pgen.1005836
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- Publication type:
- Article
Ancestral protein reconstruction: techniques and applications.
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- Biological Chemistry, 2016, v. 397, n. 1, p. 1, doi. 10.1515/hsz-2015-0158
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- Publication type:
- Article
Umwandlung einer Anthranilatsynthase in eine Isochorismatsynthase: Implikationen für die Evolution von Chorismat-umsetzenden Enzymen.
- Published in:
- Angewandte Chemie, 2015, v. 127, n. 38, p. 11423, doi. 10.1002/ange.201505063
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- Publication type:
- Article
Conversion of Anthranilate Synthase into Isochorismate Synthase: Implications for the Evolution of Chorismate-Utilizing Enzymes.
- Published in:
- Angewandte Chemie International Edition, 2015, v. 54, n. 38, p. 11270, doi. 10.1002/anie.201505063
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- Publication type:
- Article
Improving thermal and detergent stability of Bacillus stearothermophilus neopullulanase by rational enzyme design.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2015, v. 28, p. 147, doi. 10.1093/protein/gzv001
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- Publication type:
- Article
Improving thermal and detergent stability of Bacillus stearothermophilus neopullulanase by rational enzyme design.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2015, v. 28, n. 6, p. 147, doi. 10.1093/protein/gzv001
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- Publication type:
- Article
A comprehensive analysis of the geranylgeranylglyceryl phosphate synthase enzyme family identifies novel members and reveals mechanisms of substrate specificity and quaternary structure organization.
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- Molecular Microbiology, 2014, v. 92, n. 4, p. 885, doi. 10.1111/mmi.12596
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- Publication type:
- Article
Nutzung natürlicher Proteinsymmetrie zum Design lichtschaltbarer Enzyminhibitoren.
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- Angewandte Chemie, 2014, v. 126, n. 2, p. 606, doi. 10.1002/ange.201307207
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- Publication type:
- Article
Exploiting Protein Symmetry To Design Light-Controllable Enzyme Inhibitors.
- Published in:
- Angewandte Chemie International Edition, 2014, v. 53, n. 2, p. 595, doi. 10.1002/anie.201307207
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- Publication type:
- Article
Activation of a Chimeric Rpb5/RpoH Subunit Using Library Selection.
- Published in:
- PLoS ONE, 2014, v. 9, n. 1, p. 1, doi. 10.1371/journal.pone.0087485
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- Publication type:
- Article
Establishing catalytic activity on an artificial (βα)<sub>8</sub>-barrel protein designed from identical half-barrels.
- Published in:
- FEBS Letters, 2013, v. 587, n. 17, p. 2798, doi. 10.1016/j.febslet.2013.06.022
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- Publication type:
- Article
A sugar isomerization reaction established on various (βα)8-barrel scaffolds is based on substrate-assisted catalysis†.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 11, p. 751, doi. 10.1093/protein/gzs080
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- Publication type:
- Article
Corrigendum: Dimerization Determines Substrate Specificity of a Bacterial Prenyltransferase.
- Published in:
- ChemBioChem, 2012, v. 13, n. 12, p. 1710, doi. 10.1002/cbic.201200473
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- Publication type:
- Article
Random mutagenesis suggests that sequence errors are not a major cause of variation in the activity of individual molecules of β-galactosidase.
- Published in:
- Biochemistry & Cell Biology, 2012, v. 90, n. 4, p. 540, doi. 10.1139/o2012-006
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- Publication type:
- Article
Dimerization Determines Substrate Specificity of a Bacterial Prenyltransferase.
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- ChemBioChem, 2012, v. 13, n. 9, p. 1297, doi. 10.1002/cbic.201200127
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- Publication type:
- Article
Directed evolution of (βα)8-barrel enzymes: establishing phosphoribosylanthranilate isomerisation activity on the scaffold of the tryptophan synthase α-subunit.
- Published in:
- PEDS: Protein Engineering, Design & Selection, 2012, v. 25, n. 6, p. 285, doi. 10.1093/protein/gzs015
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- Publication type:
- Article
Aufklärung der Funktion eines Enzyms mit der Fähigkeit zur Synthese eines Archaea-typischen Lipids in Bacteria.
- Published in:
- Angewandte Chemie, 2011, v. 123, n. 35, p. 8338, doi. 10.1002/ange.201101832
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- Publication type:
- Article
Functional Assignment of an Enzyme that Catalyzes the Synthesis of an Archaea-Type Ether Lipid in Bacteria.
- Published in:
- Angewandte Chemie International Edition, 2011, v. 50, n. 35, p. 8188, doi. 10.1002/anie.201101832
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- Publication type:
- Article
Editorial: Directed Evolution: A Powerful Approach to Optimising and Understanding Enzymes.
- Published in:
- ChemBioChem, 2011, v. 12, n. 10, p. 1439, doi. 10.1002/cbic.201100285
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- Publication type:
- Article
Related (βα).
- Published in:
- ChemBioChem, 2011, v. 12, n. 10, p. 1487, doi. 10.1002/cbic.201100082
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- Publication type:
- Article
A Fast and Precise Approach for Computational Saturation Mutagenesis and its Experimental Validation by Using an Artificial (βα).
- Published in:
- ChemBioChem, 2011, v. 12, n. 10, p. 1544, doi. 10.1002/cbic.201100051
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- Publication type:
- Article
Stabilization of a Metabolic Enzyme by Library Selection in Thermus thermophilus.
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- ChemBioChem, 2011, v. 12, n. 10, p. 1581, doi. 10.1002/cbic.201000770
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- Publication type:
- Article
The interaction of ammonia and xenon with the imidazole glycerol phosphate synthase from Thermotoga maritima as detected by NMR spectroscopy.
- Published in:
- Protein Science: A Publication of the Protein Society, 2010, v. 19, n. 9, p. 1774, doi. 10.1002/pro.463
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- Publication type:
- Article
Hyperthermostable acetyl xylan esterase.
- Published in:
- Microbial Biotechnology, 2010, v. 3, n. 1, p. 84, doi. 10.1111/j.1751-7915.2009.00150.x
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- Publication type:
- Article
TransCent: Computational enzyme design by transferring active sites and considering constraints relevant for catalysis.
- Published in:
- BMC Bioinformatics, 2009, v. 10, p. 1, doi. 10.1186/1471-2105-10-54
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- Publication type:
- Article
A Robust Protein Host for Anchoring Chelating Ligands and Organocatalysts.
- Published in:
- ChemBioChem, 2008, v. 9, n. 4, p. 552, doi. 10.1002/cbic.200700413
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- Publication type:
- Article
Regulation of the hetero-octameric ATP phosphoribosyl transferase complex fromThermotoga maritimaby a tRNA synthetase-like subunit.
- Published in:
- Molecular Microbiology, 2005, v. 55, n. 3, p. 675, doi. 10.1111/j.1365-2958.2004.04422.x
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- Publication type:
- Article
Characterisation of a thermoalkali-stable cyclodextrin glycosyltransferase from the anaerobic thermoalkaliphilic bacteriumAnaerobranca gottschalkii.
- Published in:
- Archives of Microbiology, 2004, v. 182, n. 2/3, p. 226, doi. 10.1007/s00203-004-0717-x
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- Publication type:
- Article
Protein Design at the Crossroads of Biotechnology, Chemistry, Theory, and Evolution.
- Published in:
- 2003
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- Publication type:
- Other
Book Review: Directed Molecular Evolution of Proteins or How to Improve Enzymes for Biocatalysis. Edited by Susanne Brakmann and Kai Johnsson.
- Published in:
- ChemBioChem, 2003, v. 4, n. 1, p. 119, doi. 10.1002/cbic.200390005
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- Publication type:
- Article
A common evolutionary origin of two elementary enzyme folds
- Published in:
- FEBS Letters, 2002, v. 510, n. 3, p. 133, doi. 10.1016/S0014-5793(01)03232-X
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- Publication type:
- Article
Dissection of a (βα)<sub>8</sub>-barrel enzyme into two folded halves.
- Published in:
- Nature Structural Biology, 2001, v. 8, n. 1, p. 32
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- Publication type:
- Article