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Using a smartwatch and smartphone to assess early Parkinson's disease in the WATCH-PD study over 12 months.
- Published in:
- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00721-2
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- Publication type:
- Article
Patient-centered development of clinical outcome assessments in early Parkinson disease: key priorities and advances.
- Published in:
- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00716-z
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- Publication type:
- Article
Advancing precision medicine therapeutics for Parkinson's utilizing a shared quantitative systems pharmacology model and framework.
- Published in:
- Frontiers in Systems Biology, 2024, p. 1, doi. 10.3389/fsysb.2024.1351555
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- Publication type:
- Article
Digital technologies: Innovations that transform the face of drug development.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 8, p. 1323, doi. 10.1111/cts.13533
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- Publication type:
- Article
Empowering drug development: Leveraging insights from imaging technologies to enable the advancement of digital health technologies.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 3, p. 383, doi. 10.1111/cts.13461
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- Publication type:
- Article
Application of longitudinal item response theory models to modeling Parkinson's disease progression.
- Published in:
- CPT: Pharmacometrics & Systems Pharmacology, 2022, v. 11, n. 10, p. 1382, doi. 10.1002/psp4.12853
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- Publication type:
- Article
Identifying and characterising sources of variability in digital outcome measures in Parkinson's disease.
- Published in:
- NPJ Digital Medicine, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s41746-022-00643-4
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- Publication type:
- Article
Can Innovative Trial Designs in Orphan Diseases Drive Advancement of Treatments for Common Neurological Diseases?
- Published in:
- Clinical Pharmacology & Therapeutics, 2022, v. 111, n. 4, p. 799, doi. 10.1002/cpt.2528
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- Publication type:
- Article
Metadata Framework to Support Deployment of Digital Health Technologies in Clinical Trials in Parkinson's Disease.
- Published in:
- Sensors (14248220), 2022, v. 22, n. 6, p. 2136, doi. 10.3390/s22062136
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- Publication type:
- Article
Standardized Data Structures in Rare Diseases: CDISC User Guides for Duchenne Muscular Dystrophy and Huntington's Disease.
- Published in:
- CTS: Clinical & Translational Science, 2021, v. 14, n. 1, p. 214, doi. 10.1111/cts.12845
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- Publication type:
- Article
Challenges in Alzheimer's Disease Drug Discovery and Development: The Role of Modeling, Simulation, and Open Data.
- Published in:
- Clinical Pharmacology & Therapeutics, 2020, v. 107, n. 4, p. 796, doi. 10.1002/cpt.1782
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- Publication type:
- Article
Molecular Neuroimaging of the Dopamine Transporter as a Patient Enrichment Biomarker for Clinical Trials for Early Parkinson's Disease.
- Published in:
- CTS: Clinical & Translational Science, 2019, v. 12, n. 3, p. 240, doi. 10.1111/cts.12619
- By:
- Publication type:
- Article
New Frontiers in Parkinson's Disease: From Genetics to the Clinic.
- Published in:
- Journal of Neuroscience, 2018, v. 38, n. 44, p. 9375, doi. 10.1523/JNEUROSCI.1666-18.2018
- By:
- Publication type:
- Article
Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis.
- Published in:
- CTS: Clinical & Translational Science, 2018, v. 11, n. 1, p. 63, doi. 10.1111/cts.12492
- By:
- Publication type:
- Article
Big data to smart data in Alzheimer's disease: The brain health modeling initiative to foster actionable knowledge.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 9, p. 1014, doi. 10.1016/j.jalz.2016.04.008
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- Publication type:
- Article
Big data to smart data in Alzheimer's disease: Real-world examples of advanced modeling and simulation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 9, p. 1022, doi. 10.1016/j.jalz.2016.05.005
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- Publication type:
- Article
Development of a unified clinical trial database for Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 10, p. 1212, doi. 10.1016/j.jalz.2014.11.005
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- Publication type:
- Article
Quantifying the placebo effect through modeling and simulation.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P210, doi. 10.1016/j.jalz.2015.07.218
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- Publication type:
- Article
The path to regulatory qualification of cerebrospinal fluid biomarkers as enrichment tools in clinical trials of patients with early Alzheimer’s disease: For the coalition against major diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P296, doi. 10.1016/j.jalz.2015.07.406
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- Publication type:
- Article
The path to regulatory qualification of low baseline hippocampal volume as a prognostic biomarker in clinical trials of patients with early Alzheimer’s disease: For the coalition against major diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P404, doi. 10.1016/j.jalz.2015.06.354
- By:
- Publication type:
- Article
Modeling and simulation for medical product development and evaluation: highlights from the FDA-C-Path-ISOP 2013 workshop.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2014, v. 41, n. 6, p. 545, doi. 10.1007/s10928-014-9390-0
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- Publication type:
- Article
The Predictive Safety Testing Consortium and the Coalition Against Major Diseases.
- Published in:
- Nature Reviews Drug Discovery, 2014, v. 13, n. 11, p. 793, doi. 10.1038/nrd4440
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- Publication type:
- Article
The predictive safety testing consortium and the coalition against major diseases.
- Published in:
- 2014
- By:
- Publication type:
- journal article
Consortia driven approach to addressing clinical meaningfulness in early ad.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2014, v. 10, p. P137, doi. 10.1016/j.jalz.2014.04.082
- By:
- Publication type:
- Article
Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action.
- Published in:
- Molecular Autism, 2013, v. 4, n. 1, p. 2, doi. 10.1186/2040-2392-4-45
- By:
- Publication type:
- Article
Global standardization measurement of cerebral spinal fluid for Alzheimer's disease: An update from the Alzheimer's Association Global Biomarkers Consortium
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. 2, p. 137, doi. 10.1016/j.jalz.2012.11.003
- By:
- Publication type:
- Article
Combining patient-level and summary-level data for Alzheimer's disease modeling and simulation: a beta regression meta-analysis.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2012, v. 39, n. 5, p. 479, doi. 10.1007/s10928-012-9263-3
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- Publication type:
- Article
Advancement of a drug-disease trial model for Alzheimer's disease through a regulatory science path: The CAMD experience
- Published in:
- 2012
- By:
- Publication type:
- Abstract
Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis.
- Published in:
- Molecular Autism, 2011, v. 2, n. 1, p. 1, doi. 10.1186/2040-2392-2-7
- By:
- Publication type:
- Article
Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF-04447943
- Published in:
- 2010
- By:
- Publication type:
- Abstract
The effect of 5-lipoxygenase inhibition on Aβ and inflammation in models of Alzheimer-like pathology
- Published in:
- 2010
- By:
- Publication type:
- Abstract
[<sup>3</sup>H]DAA1106 binding to hippocampal peripheral benzodiazepine receptors in kainic acid-treated Tg2576 and C57BL6 mice
- Published in:
- 2009
- By:
- Publication type:
- Abstract
PDE9A-mediated regulation of cGMP: Developing a biomarker for a novel therapy for Alzheimer's disease
- Published in:
- 2009
- By:
- Publication type:
- Abstract
P1-063: Early-onset noradrenergic loss in Tg2576 mice: Selective vulnerability of hippocampus vs. frontal cortex
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P2-084: Application of object-based image analysis and virtual microscopy to quantify Alzheimer's disease neuropathology
- Published in:
- 2008
- By:
- Publication type:
- Abstract
Killing pain, not neurons.
- Published in:
- 2005
- By:
- Publication type:
- Letter
Cytosolic phospholipase A<sub>2</sub> is induced in reactive glia following different forms of neurodegeneration.
- Published in:
- Glia, 1999, v. 27, n. 2, p. 110, doi. 10.1002/(SICI)1098-1136(199908)27:2<110::AID-GLIA2>3.0.CO;2-C
- By:
- Publication type:
- Article
Transient Global Forebrain Ischemia Induces a Prolonged Expression of the Caspase-3 mRNA in Rat Hippocampal CA1 Pyramidal Neurons.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 1998, v. 18, n. 3, p. 248, doi. 10.1097/00004647-199803000-00003
- By:
- Publication type:
- Article
Increase in Insulin-like Growth Factor II Receptor within Ischemic Neurons Following Focal Cerebral Infarction.
- Published in:
- Journal of Cerebral Blood Flow & Metabolism, 1995, v. 15, n. 6, p. 1022, doi. 10.1038/jcbfm.1995.128
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- Publication type:
- Article
Book reviews.
- Published in:
- 1993
- By:
- Publication type:
- Book Review
Torpedo monoclonal antibodies react with components of the human peripheral nervous system.
- Published in:
- Muscle & Nerve, 1988, v. 11, n. 1, p. 10, doi. 10.1002/mus.880110105
- By:
- Publication type:
- Article
Pseudomembranous colitis associated with antibiotic therapy -- an emerging entity.
- Published in:
- Canadian Medical Association Journal, 1974, v. 111, n. 10, p. 1110
- By:
- Publication type:
- Article