Works by Stepanov, Irina

Results: 54

How people think about the chemicals in cigarette smoke: a systematic review.

Published in:

Journal of Behavioral Medicine, 2017, v. 40, n. 4, p. 553, doi. 10.1007/s10865-017-9823-5

By:

Morgan, Jennifer;
Byron, M.;
Baig, Sabeeh;
Stepanov, Irina;
Brewer, Noel

Publication type:

Article

A response from Morgan, Byron, Baig, Stepanov and Brewer.

Published in:

2017

By:

Morgan, Jennifer;
Byron, M.;
Baig, Sabeeh;
Stepanov, Irina;
Brewer, Noel

Publication type:

Letter

Self-reported Tobacco use does not correlate with carcinogen exposure in smokers with head and neck cancer.

Published in:

Laryngoscope, 2015, v. 125, n. 8, p. 1844, doi. 10.1002/lary.25290

By:

Khariwala, Samir S.;
Carmella, Steven G.;
Stepanov, Irina;
Bandyopadhyay, Dipankar;
Nelson, Heather H.;
Yueh, Bevan;
Hatsukami, Dorothy K.;
Hecht, Stephen S.

Publication type:

Article

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients.

Published in:

Carcinogenesis, 2019, v. 40, n. 11, p. 1387, doi. 10.1093/carcin/bgz053

By:

Ma, Bin;
Villalta, Peter W;
Hochalter, J Bradley;
Stepanov, Irina;
Hecht, Stephen S

Publication type:

Article

Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Published in:

Carcinogenesis, 2018, v. 39, n. 2, p. 232, doi. 10.1093/carcin/bgx135

By:

Bin Ma;
Zarth, Adam T.;
Carlson, Erik S.;
Villalta, Peter W.;
Upadhyaya, Pramod;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

(S)-N′-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats.

Published in:

Carcinogenesis, 2013, v. 34, n. 9, p. 2178, doi. 10.1093/carcin/bgt162

By:

Balbo, Silvia;
James-Yi, Sandra;
Johnson, Charles S.;
O’Sullivan, Michael G.;
Stepanov, Irina;
Wang, Mingyao;
Bandyopadhyay, Dipankar;
Kassie, Fekadu;
Carmella, Steven;
Upadhyaya, Pramod;
Hecht, Stephen S.

Publication type:

Article

Alaska Native smokers and smokeless tobacco users with slower CYP2A6 activity have lower tobacco consumption, lower tobacco-specific nitrosamine exposure and lower tobacco-specific nitrosamine bioactivation.

Published in:

Carcinogenesis, 2013, v. 34, n. 1, p. 93, doi. 10.1093/carcin/bgs306

By:

Zhu, Andy Z.X.;
Binnington, Matthew J.;
Renner, Caroline C.;
Lanier, Anne P.;
Hatsukami, Dorothy K.;
Stepanov, Irina;
Watson, Clifford H.;
Sosnoff, Connie S.;
Benowitz, Neal L.;
Tyndale, Rachel F.

Publication type:

Article

Urinary levels of the tobacco-specific carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.

Published in:

Carcinogenesis, 2011, v. 32, n. 9, p. 1366, doi. 10.1093/carcin/bgr125

By:

Yuan, Jian-Min;
Knezevich, Aleksandar D.;
Wang, Renwei;
Gao, Yu-Tang;
Hecht, Stephen S.;
Stepanov, Irina

Publication type:

Article

Harm Perceptions of Tobacco/Nicotine Products and Child Exposure: Differences between Non-Users, Cigarette-Exclusive, and Electronic Cigarette-Exclusive Users.

Published in:

Tobacco Use Insights, 2021, p. 1, doi. 10.1177/1179173X21998362

By:

Tackett, Alayna P;
Wallace, Samantha W;
Smith, Caitlin E;
Turner, Elise;
Fedele, David A;
Stepanov, Irina;
Lechner, William V;
Hale, Jessica J;
Wagener, Theodore L

Publication type:

Article

Harm Perceptions of Tobacco/Nicotine Products and Child Exposure: Differences between Non-Users, Cigarette-Exclusive, and Electronic Cigarette-Exclusive Users.

Published in:

Tobacco Use Insights, 2021, p. 1, doi. 10.1177/1179173X21998362

By:

Tackett, Alayna P;
Wallace, Samantha W;
Smith, Caitlin E;
Turner, Elise;
Fedele, David A;
Stepanov, Irina;
Lechner, William V;
Hale, Jessica J;
Wagener, Theodore L

Publication type:

Article

Genome-wide association study of urinary cadmium levels in current smokers from the multiethnic cohort study.

Published in:

Human Molecular Genetics, 2025, v. 34, n. 7, p. 611, doi. 10.1093/hmg/ddae202

By:

Sullivan, Shannon M;
Murphy, Sharon E;
Stram, Daniel O;
Wilkens, Lynne R;
Haiman, Christopher A;
Marchand, Loïc Le;
Stepanov, Irina;
Park, S Lani

Publication type:

Article

Tobacco-specific nitrosamines in smokeless tobacco products marketed in India.

Published in:

International Journal of Cancer, 2005, v. 116, n. 1, p. 16, doi. 10.1002/ijc.20966

By:

Stepanov, Irina;
Hecht, Stephen S.;
Ramakrishnan, Sreevidya;
Gupta, Prakash C.

Publication type:

Article

"Cold turkey" or pharmacotherapy: Examination of tobacco cessation methods tried among smokers prior to developing head and neck cancer.

Published in:

Head & Neck, 2019, v. 41, n. 7, p. 2332, doi. 10.1002/hed.25708

By:

Khariwala, Samir S.;
Rubin, Nathan;
Stepanov, Irina;
Nollen, Nicole;
Ahluwalia, Jasjit S.;
Nelson, Heather H.;
Hatsukami, Dorothy K.

Publication type:

Article

Elevated levels of 1-hydroxypyrene and N′-nitrosonornicotine in smokers with head and neck cancer: A matched control study.

Published in:

Head & Neck, 2013, v. 35, n. 8, p. 1096, doi. 10.1002/hed.23085

By:

Khariwala, Samir S.;
Carmella, Steven G.;
Stepanov, Irina;
Fernandes, Patricia;
Lassig, Amy Anne;
Yueh, Bevan;
Hatsukami, Dorothy;
Hecht, Stephen S.

Publication type:

Article

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers.

Published in:

NPJ Precision Oncology, 2018, v. 2, n. 1, p. N.PAG, doi. 10.1038/s41698-018-0057-y

By:

Murphy, Sharon E.;
Park, Sungshim Lani;
Balbo, Silvia;
Haiman, Christopher A.;
Hatsukami, Dorothy K.;
Patel, Yesha;
Peterson, Lisa A.;
Stepanov, Irina;
Stram, Daniel O.;
Tretyakova, Natalia;
Hecht, Stephen S.;
Le Marchand, Loïc

Publication type:

Article

Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation.

Published in:

Addiction, 2010, v. 105, n. 2, p. 343, doi. 10.1111/j.1360-0443.2009.02780.x

By:

Hatsukami, Dorothy K.;
Kotlyar, Michael;
Hertsgaard, Louise A.;
Zhang, Yan;
Carmella, Steven G.;
Jensen, Joni A.;
Allen, Sharon S.;
Shields, Peter G.;
Murphy, Sharon E.;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

Elevated Urinary 1‐HOP, NNN, and NNAL in Smokers with Head and Neck Squamous Cell Carcinoma.

Published in:

2011

By:

Khariwala, Samir;
Hatsukami, Dorothy;
Stepanov, Irina;
Hecht, Stephen;
Fernandes, Patricia;
Lassig, Amy Anne D.;
Yueh, Bevan

Publication type:

Abstract

The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is significantly higher in passive than in active smokers.

Published in:

Biomarkers, 2011, v. 16, n. 6, p. 491, doi. 10.3109/1354750X.2011.598565

By:

Vogel, Rachel I.;
Carmella, Steven G.;
Stepanov, Irina;
Hatsukami, Dorothy K.;
Hecht, Stephen S.

Publication type:

Article

Measuring the impact of manganese exposure on children's neurodevelopment: advances and research gaps in biomarker-based approaches.

Published in:

2016

By:

Coetzee, Donna J.;
McGovern, Patricia M.;
Rao, Raghavendra;
Harnack, Lisa J.;
Georgieff, Michael K.;
Stepanov, Irina

Publication type:

journal article

5. Biomarkers of exposure, effect and susceptibility for assessing electronic nicotine delivery devices and heated tobacco products, and their possible prioritization.

Published in:

WHO Technical Report Series, 2023, n. 1047, p. 87

By:

Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

Toxicants in heated tobacco products, exposure, health effects and claims of reduced risk.

Published in:

WHO Technical Report Series, 2021, n. 1029, p. 7

By:

Stepanov, Irina;
Mattioli, Federica;
Davoli, Enrico

Publication type:

Article

Tobacco carcinogen research to aid understanding of cancer risk and influence policy.

Published in:

Laryngoscope Investigative Otolaryngology, 2018, v. 3, n. 5, p. 372, doi. 10.1002/lio2.204

By:

Singhavi, Hitesh;
Ahluwalia, Jasjit S.;
Stepanov, Irina;
Gupta, Prakash C.;
Gota, Vikram;
Chaturvedi, Pankaj;
Khariwala, Samir S.

Publication type:

Article

Simultaneous analysis of urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, N′-nitrosonornicotine, and cotinine by liquid chromatography-tandem mass-spectrometry.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-99259-z

By:

Nikam, Sampada S.;
Gurjar, Murari;
Singhavi, Hitesh;
Patil, Anand;
Singh, Arjun;
Villalta, Peter;
Chaturvedi, Pankaj;
Khariwala, Samir S.;
Gota, Vikram;
Stepanov, Irina

Publication type:

Article

Estimating the Causal Effect of Filter Ventilation Levels in Cigarettes on Past 30-Day Smoking.

Published in:

Nicotine & Tobacco Research, 2025, v. 27, n. 2, p. 192, doi. 10.1093/ntr/ntae191

By:

Eaton, Anne A;
Hatsukami, Dorothy K;
Stepanov, Irina;
Shields, Peter G;
Carroll, Dana Mowls

Publication type:

Article

Can the Public Be Educated About Constituents in Smokeless Tobacco? A Three-Wave Randomized Controlled Trial.

Published in:

2021

By:

Loken, Barbara;
Borgida, Eugene;
Wang, Tzushuo;
Madzelan, Molly K;
Williams, Allison L;
Hatsukami, Dorothy;
Stepanov, Irina

Publication type:

journal article

Relationships Between Race, Gender, and Spot Urine Levels of Biomarkers of Tobacco Exposure Vary Based on How Creatinine Is Handled in Analyses.

Published in:

2020

By:

Carroll, Dana M;
Cigan, Shannon;
Ikuemonisan, Joshua;
Hammonds, Taylor;
Stepanov, Irina;
Helen, Gideon St.;
Benowitz, Neal;
Hatsukami, Dorothy K;
St Helen, Gideon

Publication type:

journal article

Cigarette Smokers Versus Cousers of Cannabis and Cigarettes: Exposure to Toxicants.

Published in:

2020

By:

Meier, Ellen;
Vandrey, Ryan;
Rubin, Nathan;
Pacek, Lauren R;
Jensen, Joni A;
Donny, Eric C;
Hecht, Stephen S;
Carmella, Steven G;
Murphy, Sharon E;
Luo, Xianghua;
Stepanov, Irina;
Ikuemonisan, Joshua;
Severson, Herb;
Al'absi, Mustafa;
Hatsukami, Dorothy K

Publication type:

journal article

A Randomized Clinical Trial of Snus Examining the Effect of Complete Versus Partial Cigarette Substitution on Smoking-Related Behaviors, and Biomarkers of Exposure.

Published in:

2020

By:

Meier, Ellen;
Lindgren, Bruce R;
Anderson, Amanda;
Reisinger, Sarah A;
Norton, Kaila J;
Jensen, Joni;
Strayer, Lori;
Dick, Laura;
Tang, Mei-Kuen;
Chen, Menglan;
Carmella, Steven G;
Hecht, Stephen S;
Murphy, Sharon E;
Yang, Jing;
Stepanov, Irina;
O'Connor, Richard J;
Shields, Peter G;
Hatsukami, Dorothy K

Publication type:

journal article

Consortium on Methods Evaluating Tobacco: Research Tools to Inform US Food and Drug Administration Regulation of Snus.

Published in:

2018

By:

Berman, Micah L;
Bickel, Warren K;
Harris, Andrew C;
LeSage, Mark G;
O'Connor, Richard J;
Stepanov, Irina;
Shields, Peter G;
Hatsukami, Dorothy K

Publication type:

journal article

Effective Message Elements for Disclosures About Chemicals in Cigarette Smoke.

Published in:

2018

By:

Kelley, Dannielle E;
Boynton, Marcella H;
Noar, Seth M;
Morgan, Jennifer C;
Mendel, Jennifer R;
Ribisl, Kurt M;
Stepanov, Irina;
Nylander-French, Leena A;
Brewer, Noel T

Publication type:

journal article

Assessing Constituent Levels in Smokeless Tobacco Products: A New Approach to Engaging and Educating the Public.

Published in:

2015

By:

Borgida, Eugene;
Loken, Barbara;
Williams, Allison L.;
Vitriol, Joseph;
Stepanov, Irina;
Hatsukami, Dorothy

Publication type:

journal article

Monitoring Tobacco-Specific N-Nitrosamines and Nicotine in Novel Smokeless Tobacco Products: Findings From Round II of the New Product Watch.

Published in:

Nicotine & Tobacco Research, 2014, v. 16, n. 8, p. 1070, doi. 10.1093/ntr/ntu026

By:

Stepanov, Irina;
Biener, Lois;
Yershova, Katrina;
Nyman, Amy L.;
Bliss, Robin;
Parascandola, Mark;
Hatsukami, Dorothy K.

Publication type:

Article

Levels of (S)-N′-Nitrosonornicotine in U.S. Tobacco Products.

Published in:

Nicotine & Tobacco Research, 2013, v. 15, n. 7, p. 1305, doi. 10.1093/ntr/nts249

By:

Stepanov, Irina;
Yershova, Katrina;
Carmella, Steven;
Upadhyaya, Pramod;
Hecht, Stephen S.

Publication type:

Article

Nornicotine Nitrosation in Saliva and Its Relation to Endogenous Synthesis of N′-Nitrosonornicotine in Humans.

Published in:

Nicotine & Tobacco Research, 2013, v. 15, n. 2, p. 591, doi. 10.1093/ntr/nts172

By:

Knezevich, Aleksandar;
Muzic, John;
Hatsukami, Dorothy K.;
Hecht, Stephen S.;
Stepanov, Irina

Publication type:

Article

Increased Pouch Sizes and Resulting Changes in the Amounts of Nicotine and Tobacco-Specific N-Nitrosamines in Single Pouches of Camel Snus and Marlboro Snus.

Published in:

Nicotine & Tobacco Research, 2012, v. 14, n. 10, p. 1241, doi. 10.1093/ntr/ntr292

By:

Stepanov, Irina;
Jensen, Joni;
Biener, Lois;
Bliss, Robin L.;
Hecht, Stephen S.;
Hatsukami, Dorothy K.

Publication type:

Article

Monitoring Tobacco-Specific N-Nitrosamines and Nicotine in Novel Marlboro and Camel Smokeless Tobacco Products: Findings From Round 1 of the New Product Watch.

Published in:

Nicotine & Tobacco Research, 2012, v. 14, n. 3, p. 274, doi. 10.1093/ntr/ntr209

By:

Stepanov, Irina;
Biener, Lois;
Knezevich, Aleksandar;
Nyman, Amy L.;
Bliss, Robin;
Jensen, Joni;
Hecht, Stephen S.;
Hatsukami, Dorothy K.

Publication type:

Article

Cigarette Smoke Extract, but Not Electronic Cigarette Aerosol Extract, Inhibits Monoamine Oxidase in vitro and Produces Greater Acute Aversive/Anhedonic Effects Than Nicotine Alone on Intracranial Self-Stimulation in Rats.

Published in:

Frontiers in Neuroscience, 2022, p. 1, doi. 10.3389/fnins.2022.868088

By:

Harris, Andrew C.;
Muelken, Peter;
Alcheva, Aleksandra;
Stepanov, Irina;
LeSage, Mark G.

Publication type:

Article

Toenail manganese as a potential biomarker for in utero and early childhood exposure studies.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-35112-0

By:

Cigan, Shannon S.;
McGovern, Patricia M.;
Choudhary, Kriti;
Miller, Neely C.;
Georgieff, Michael;
Rao, Raghavendra;
Stepanov, Irina

Publication type:

Article

Effects of Drying Methods on the Phytochemical Contents, Antioxidant Properties, and Anti-Diabetic Activity of Nasturtium officinale R.Br. (Betong Watercress) from Southern Thailand.

Published in:

Life (2075-1729), 2024, v. 14, n. 9, p. 1204, doi. 10.3390/life14091204

By:

Kijkuokool, Praporn;
Stepanov, Irina;
Ounjaijean, Sakaewan;
Koonyosying, Pimpisid;
Rerkasem, Kittipan;
Chuljerm, Hataichanok;
Parklak, Wason;
Kulprachakarn, Kanokwan

Publication type:

Article

Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats.

Published in:

Psychopharmacology, 2012, v. 220, n. 3, p. 565, doi. 10.1007/s00213-011-2514-y

By:

Harris, Andrew;
Stepanov, Irina;
Pentel, Paul;
LeSage, Mark

Publication type:

Article

Genome-wide mapping of 8-oxo-7,8-dihydro-2′-deoxyguanosine reveals accumulation of oxidatively-generated damage at DNA replication origins within transcribed long genes of mammalian cells.

Published in:

Nucleic Acids Research, 2019, v. 47, n. 1, p. 221, doi. 10.1093/nar/gky1152

By:

Amente, Stefano;
Di Palo, Giacomo;
Scala, Giovanni;
Castrignanò, Tiziana;
Gorini, Francesca;
Cocozza, Sergio;
Moresano, Angela;
Pucci, Piero;
Ma, Bin;
Stepanov, Irina;
Lania, Luigi;
Pelicci, Pier Giuseppe;
Dellino, Gaetano Ivan;
Majello, Barbara

Publication type:

Article

Patterns of Tobacco Cessation Attempts and Symptoms Experienced Among Smokers With Head and Neck Squamous Cell Carcinoma.

Published in:

2018

By:

Khariwala, Samir S.;
Hatsukami, Dorothy K.;
Stepanov, Irina;
Rubin, Nathan;
Nelson, Heather H.

Publication type:

journal article

Tobacco-specific N-nitrosamines and polycyclic aromatic hydrocarbons in cigarettes smoked by the participants of the Shanghai Cohort Study.

Published in:

International Journal of Cancer, 2016, v. 139, n. 6, p. 1261, doi. 10.1002/ijc.30178

By:

Yershova, Katrina;
Yuan, Jian‐Min;
Wang, Renwei;
Valentin, Liza;
Watson, Clifford;
Gao, Yu‐Tang;
Hecht, Stephen S.;
Stepanov, Irina

Publication type:

Article

Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai cohort study: Remarkable coherence with rat tumor sites.

Published in:

International Journal of Cancer, 2014, v. 134, n. 10, p. 2278, doi. 10.1002/ijc.28575

By:

Stepanov, Irina;
Sebero, Erin;
Wang, Renwei;
Gao, Yu‐Tang;
Hecht, Stephen S.;
Yuan, Jian‐Min

Publication type:

Article

Cigarette Relighting: A Series of Pilot Studies Investigating a Common Yet Understudied Smoking Behavior.

Published in:

International Journal of Environmental Research & Public Health, 2021, v. 18, n. 12, p. 6494, doi. 10.3390/ijerph18126494

By:

Heckman, Carolyn J.;
Wackowski, Olivia A.;
Mukherjee, Rohit;
Hatsukami, Dorothy K.;
Stepanov, Irina;
Delnevo, Cristine D.;
Steinberg, Michael B.

Publication type:

Article

Ethnic Differences of Urinary Cadmium in Cigarette Smokers from the Multiethnic Cohort Study.

Published in:

International Journal of Environmental Research & Public Health, 2021, v. 18, n. 5, p. 2669, doi. 10.3390/ijerph18052669

By:

Cigan, Shannon S.;
Murphy, Sharon E.;
Alexander, Bruce H.;
Stram, Daniel O.;
Hatsukami, Dorothy K.;
Le Marchand, Loic;
Park, Sungshim L.;
Stepanov, Irina;
Merianos, Ashley L.;
Mahabee-Gittens, E. Melinda

Publication type:

Article

Pyridylhydroxybutyl and pyridyloxobutyl DNA phosphate adduct formation in rats treated chronically with enantiomers of the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

Published in:

Mutagenesis, 2017, v. 32, n. 6, p. 561, doi. 10.1093/mutage/gex031

By:

Bin Ma;
Zarth, Adam T.;
Carlson, Erik S.;
Villalta, Peter W.;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

Recent Studies on DNA Adducts Resulting from Human Exposure to Tobacco Smoke.

Published in:

Toxics, 2019, v. 7, n. 1, p. 16, doi. 10.3390/toxics7010016

By:

Ma, Bin;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

Evidence for endogenous formation of N'-nitrosonornicotine in some long-term nicotine patch users.

Published in:

2009

By:

Stepanov I;
Carmella SG;
Han S;
Pinto A;
Strasser AA;
Lerman C;
Hecht SS;
Stepanov, Irina;
Carmella, Steven G;
Han, Shaomei;
Pinto, Angela;
Strasser, Andrew A;
Lerman, Caryn;
Hecht, Stephen S

Publication type:

journal article

Evidence for endogenous formation of N′-nitrosonornicotine in some long-term nicotine patch users.

Published in:

Nicotine & Tobacco Research, 2009, v. 11, n. 1, p. 99, doi. 10.1093/ntr/ntn004

By:

Stepanov, Irina;
Carmella, Steven G.;
Han, Shaomei;
Pinto, Angela;
Strasser, Andrew A.;
Lerman, Caryn;
Hecht, Stephen S.

Publication type:

Article