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Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors.
Published in:
Oncogene, 2008, v. 27, n. 29, p. 4086, doi. 10.1038/onc.2008.49
By:
- Steelman, L. S.;
- Navolanic, P. M.;
- Sokolosky, M. L.;
- Taylor, J. R.;
- Lehmann, B. D.;
- Chappell, W. H.;
- Abrams, S. L.;
- Wong, E. W. T.;
- Stadelman, K. M.;
- Terrian, D. M.;
- Leslie, N. R.;
- Martelli, A. M.;
- Stivala, F.;
- Libra, M.;
- Franklin, R. A.;
- McCubrey, J. A.
Publication type:
Article
Direct radiocarbon dating of megalithic paints from north-west Iberia.
Published in:
Antiquity, 2005, v. 79, n. 304, p. 379, doi. 10.1017/S0003598X00114164
By:
- Steelman, K. L.;
- Ramírez, F. Carrera;
- Valcarce, R. Fábregas;
- Guilderson, T.;
- Rowe, M. W.
Publication type:
Article
Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells.
Published in:
2001
By:
- McCubrey, J A;
- Blalock, W L;
- Saleh, O;
- Pearce, M;
- Burrows, C;
- Steelman, L S;
- Lee, J T;
- Franklin, R A;
- Oberhaus, S M;
- Moye, P W;
- Doshi, P D;
- McKearn, J P
Publication type:
journal article
Oncogene-dependent engraftment of human myeloid leukemia cells in immunosuppressed mice.
Published in:
2001
By:
- Kiser, M;
- McCubrey, J A;
- Steelman, L S;
- Shelton, J G;
- Ramage, J;
- Alexander, R L;
- Kucera, G L;
- Pettenati, M;
- Willingham, M C;
- Miller, M S;
- Frankel, A E
Publication type:
journal article
Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells.
Published in:
2001
By:
- Blalock, W L;
- Pearce, M;
- Chang, F;
- Lee, J T;
- Pohnert, S C;
- Burrows, C;
- Steelman, L S;
- Franklin, R A;
- McMahon, M;
- McCubrey, J A
Publication type:
journal article
Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells.
Published in:
2000
By:
- Weinstein-Oppenheimer, C;
- Steelman, L S;
- Algate, P A;
- Blalock, W L;
- Burrows, C;
- Hoyle, P E;
- Lee, J T;
- Moye, P W;
- Shelton, J G;
- Franklin, R;
- McCubrey, J A
Publication type:
journal article
Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.
Published in:
2000
By:
- Moye, P W;
- Blalock, W L;
- Hoyle, P E;
- Chang, F;
- Franklin, R A;
- Weinstein-Oppenheimer, C;
- Pearce, M;
- Steelman, L;
- McMahon, M;
- McCubrey, J A
Publication type:
journal article
Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.
Published in:
2000
By:
- Blalock, W L;
- Moye, P W;
- Chang, F;
- Pearce, M;
- Steelman, L S;
- McMahon, M;
- McCubrey, J A
Publication type:
journal article
Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism.
Published in:
2000
By:
- Hoyle, P E;
- Moye, P W;
- Steelman, L S;
- Blalock, W L;
- Franklin, R A;
- Pearce, M;
- Cherwinski, H;
- Bosch, E;
- McMahon, M;
- McCubrey, J A
Publication type:
journal article
Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs.
Published in:
1999
By:
- Blalock, W L;
- Weinstein-Oppenheimer, C;
- Chang, F;
- Hoyle, P E;
- Wang, X-Y;
- Algate, P A;
- Franklin, R A;
- Oberhaus, S M;
- Steelman, L S;
- McCubrey, J A
Publication type:
journal article
Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells.
Published in:
1998
By:
- McCubrey, J A;
- Steelman, L S;
- Hoyle, P E;
- Blalock, W L;
- Weinstein-Oppenheimer, C;
- Franklin, R A;
- Cherwinski, H;
- Bosch, E;
- McMahon, M
Publication type:
journal article
Steric hindrance effects on bimolecular coupling rate constants of carbon-centered radicals.
Published in:
Journal of Physical Organic Chemistry, 2000, v. 13, n. 11, p. 735, doi. 10.1002/1099-1395(200011)13:11<735::AID-POC310>3.0.CO;2-Z
By:
- Gostowski, Rudy C.;
- Bailey, Terry;
- Bonner, Sabrinia D.;
- Emrich, Erin E.;
- Steelman, Stephanie L.
Publication type:
Article
Effects of a Self-Management with Peer Training Intervention on Academic Engagement for High School Students with Autism Spectrum Disorder.
Published in:
Journal of Behavioral Education, 2019, v. 28, n. 4, p. 456, doi. 10.1007/s10864-018-09317-2
By:
- Roberts, Garrett J.;
- Mize, Min;
- Reutebuch, Colleen K.;
- Falcomata, Terry;
- Capin, Philip;
- Steelman, Briana L.
Publication type:
Article
A Study of the Effects of a New Anti-Androgen on the Hyperplastic Dog Prostate.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1973, v. 143, n. 3, p. 647, doi. 10.3181/00379727-143-37384
By:
- Brooks, J. R.;
- Busch, R. D.;
- Patanelli, D. J.;
- Steelman, S. L.
Publication type:
Article
The Effect of a New Anti-androgen on Canine Prostatic Acid Phosphatase.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1973, v. 142, n. 4, p. 1063, doi. 10.3181/00379727-142-37177
By:
- Brooks, J. R.;
- Busch, R. D.;
- Lopez-Ramos, B.;
- Holt, W. R.;
- Steelman, S. L.;
- Patanelli, D. J.
Publication type:
Article
The Effect of the Implantation of Spirometra mansonoides Spargana in the Growing Rat.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1971, v. 138, n. 2, p. 610, doi. 10.3181/00379727-138-35952
By:
- Glitzer, Monroe S.;
- Steelman, Sanford L.
Publication type:
Article
Uterotropic and Anti-Implantation Activities of Certain Resorcylic Acid Lactone Derivatives.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1971, v. 137, n. 1, p. 101, doi. 10.3181/00379727-137-35521
By:
- Brooks, J. R.;
- Steelman, S. L.;
- Patanelli, D. J.
Publication type:
Article
Growth Hormone-Like Activity in Hypophysectomized Rats Implanted with Spirometra Mansonoides Spargana.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1970, v. 133, n. 1, p. 269, doi. 10.3181/00379727-133-34453
By:
- Steelman, Sanford L.;
- Morgan, Evan R.;
- Cuccaro, Anthony J.;
- Glitzer, Monroe S.
Publication type:
Article
A Phase I dose-escalation study of the VEGFR inhibitor tivozanib hydrochloride with weekly paclitaxel in metastatic breast cancer.
Published in:
Breast Cancer Research & Treatment, 2013, v. 140, n. 2, p. 331, doi. 10.1007/s10549-013-2632-9
By:
- Mayer, Erica;
- Scheulen, M.;
- Beckman, J.;
- Richly, H.;
- Duarte, A.;
- Cotreau, M.;
- Strahs, A.;
- Agarwal, S.;
- Steelman, L.;
- Winer, E.;
- Dickler, M.
Publication type:
Article
Separate but Faithful: The Christian Right's Radical Struggle to Transform Law and Legal Culture. By Amanda Hollis-Brusky and Joshua C. Wilson.
Published in:
Journal of Church & State, 2021, v. 63, n. 4, p. 751, doi. 10.1093/jcs/csab068
By:
- Steelman, Austin L
Publication type:
Article
PL3.1 A phase 1, open-label, perioperative study of ivosidenib (AG-120) and vorasidenib (AG-881) in recurrent, IDH1-mutant, low-grade glioma: results from cohort 1.
Published in:
Neuro-Oncology, 2019, v. 21, p. iii2, doi. 10.1093/neuonc/noz126.004
By:
- Mellinghoff, I K;
- Wen, P Y;
- Taylor, J W;
- Maher, E A;
- Arrillaga-Romany, I;
- Peters, K B;
- Le, K;
- Tai, F;
- Steelman, L;
- Cloughesy, T F
Publication type:
Article
N-Amidino-3,5-diamino-6-chloropyrazine-carboxamide : an Active Diuretic in the Carboxamide Series.
Published in:
Nature, 1966, v. 212, n. 5058, p. 191, doi. 10.1038/212191a0
By:
- GLITZER, M. S.;
- STEELMAN, S. L.
Publication type:
Article
Preparation of Rat Growth Hormone.
Published in:
Nature, 1964, v. 201, n. 4921, p. 821, doi. 10.1038/201821a0
By:
- REISFELD, R. A.;
- MUCCILLI, A. S.;
- WILLIAMS, D. E.;
- STEELMAN, S. L.
Publication type:
Article
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
Published in:
2014
By:
- McCubrey, J A;
- Steelman, L S;
- Bertrand, F E;
- Davis, N M;
- Abrams, S L;
- Montalto, G;
- D'Assoro, A B;
- Libra, M;
- Nicoletti, F;
- Maestro, R;
- Basecke, J;
- Cocco, L;
- Cervello, M;
- Martelli, A M
Publication type:
journal article
Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention.
Published in:
Leukemia (08876924), 2014, v. 28, n. 1, p. 15, doi. 10.1038/leu.2013.184
By:
- McCubrey, J A;
- Steelman, L S;
- Bertrand, F E;
- Davis, N M;
- Abrams, S L;
- Montalto, G;
- D'Assoro, A B;
- Libra, M;
- Nicoletti, F;
- Maestro, R;
- Basecke, J;
- Cocco, L;
- Cervello, M;
- Martelli, A M
Publication type:
Article
Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy.
Published in:
2011
By:
- Steelman, L. S.;
- Franklin, R. A.;
- Abrams, S. L.;
- Chappell, W.;
- Kempf, C. R.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, P.;
- Ruvolo, V.;
- Evangelisti, C.;
- Martelli, A. M.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
Published in:
2011
By:
- Martelli, A. M.;
- Evangelisti, C.;
- Chappell, W.;
- Abrams, S. L.;
- Bäsecke, J.;
- Stivala, F.;
- Donia, M.;
- Fagone, P.;
- Nicoletti, F.;
- Libra, M.;
- Ruvolo, V.;
- Ruvolo, P.;
- Kempf, C. R.;
- Steelman, L. S.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy.
Published in:
2009
By:
- Misaghian, N;
- Ligresti, G;
- Steelman, L S;
- Bertrand, F E;
- Bäsecke, J;
- Libra, M;
- Nicoletti, F;
- Stivala, F;
- Milella, M;
- Tafuri, A;
- Cervello, M;
- Martelli, A M;
- McCubrey, J A;
- Bäsecke, J
Publication type:
journal article
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.
Published in:
2008
By:
- McCubrey, J. A.;
- Abrams, S. L.;
- Ligresti, G.;
- Misaghian, N.;
- Wong, E. W. T.;
- Steelman, L. S.;
- Bäsecke, J.;
- Troppmair, J.;
- Libra, M.;
- Nicoletti, F.;
- Molton, S.;
- McMahon, M.;
- Evangelisti, C.;
- Martelli, A. M.;
- Bäsecke, J
Publication type:
journal article
Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia.
Published in:
2008
By:
- Steelman, L. S.;
- Abrams, S. L.;
- Whelan, J.;
- Bertrand, F. E.;
- Ludwig, D. E.;
- Bäsecke, J.;
- Libra, M.;
- Stivala, F.;
- Milella, M.;
- Tafuri, A.;
- Lunghi, P.;
- Bonati, A.;
- Martelli, A. M.;
- McCubrey, J. A.;
- Bäsecke, J
Publication type:
journal article
Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy.
Published in:
Leukemia (08876924), 2008, v. 22, n. 4, p. 708, doi. 10.1038/leu.2008.27
By:
- McCubrey, J. A.;
- Steelman, L. S.;
- Abrams, S. L.;
- Bertrand, F. E.;
- Ludwig, D. E.;
- Bäsecke, J.;
- Libra, M.;
- Stivala, F.;
- Milella, M.;
- Tafuri, A.;
- Lunghi, P.;
- Bonati, A.;
- Martelli, A. M.
Publication type:
Article
Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells.
Published in:
Leukemia (08876924), 2006, v. 20, n. 7, p. 1254, doi. 10.1038/sj.leu.2404217
By:
- Bertrand, F E;
- Steelman, L S;
- Chappell, W H;
- Abrams, S L;
- Shelton, J G;
- White, E R;
- Ludwig, D L;
- McCubrey, J A
Publication type:
Article
Regulation and targeting of antiapoptotic XIAP in acute myeloid leukemia.
Published in:
Leukemia (08876924), 2003, v. 17, n. 11, p. 2081, doi. 10.1038/sj.leu.2403113
By:
- Carter, B. Z.;
- Milella, M.;
- Tsao, T.;
- McQueen, T.;
- Schober, W. D.;
- Hu, W.;
- Dean, N. M.;
- Steelman, L.;
- McCubrey, J. A.;
- Andreeff, M.
Publication type:
Article
Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.
Published in:
Leukemia (08876924), 2003, v. 17, n. 7, p. 1263, doi. 10.1038/sj.leu.2402945
By:
- Chang, F;
- Steelman, L S;
- Lee, J T;
- Shelton, J G;
- Navolanic, P M;
- Blalock, W L;
- Franklin, R A;
- McCubrey, J A
Publication type:
Article
Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
Published in:
2003
By:
- Blalock, W L;
- Navolanic, P M;
- Steelman, L S;
- Shelton, J G;
- Moye, P W;
- Lee, J T;
- Franklin, R A;
- Mirza, A;
- McMahon, M;
- White, M K;
- McCubrey, J A
Publication type:
journal article
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.
Published in:
Leukemia (08876924), 2003, v. 17, n. 3, p. 590, doi. 10.1038/sj.leu.2402824
By:
- Chang, F;
- Lee, J T;
- Navolanic, P M;
- Steelman, L S;
- Shelton, J G;
- Blalock, W L;
- Franklin, R A;
- McCubrey, J A
Publication type:
Article
Portable X‐Ray Fluorescence Spectroscopy of Pictographs: A Case Study From the Lower Pecos Canyonlands, Texas.
Published in:
Archaeometry, 2014, v. 56, p. 168, doi. 10.1111/arcm.12060
By:
- Koenig, C. W.;
- Castañeda, A. M.;
- Boyd, C. E.;
- Rowe, M. W.;
- Steelman, K. L.
Publication type:
Article
Cova Eirós: An Integrated Approach to Dating the Earliest Known Cave Art in NW Iberia.
Published in:
Radiocarbon, 2017, v. 59, n. 1, p. 151, doi. 10.1017/RDC.2017.4
By:
- Steelman, Karen L;
- de Lombera-Hermida, Arturo;
- Viñas-Vallverdú, Ramón;
- Rodríguez-Álvarez, Xosé Pedro;
- Carrera-Ramírez, Fernando;
- Rubio-Mora, Albert;
- Fábregas-Valcarce, Ramon
Publication type:
Article
Purification of Growth Hormone-Releasing Factor from Beef Hypothalamus.∗.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1966, v. 122, n. 3, p. 821, doi. 10.3181/00379727-122-31260
By:
- Schally, Andrew V.;
- Kuroshima, Akihiro;
- Ishida, Yuichi;
- Arimura, Akira;
- Saito, Takashige;
- Bowers, Cyril Y.;
- Steelman, Sanford L.
Publication type:
Article
N-Amidino-3-Amino-6-Chloropyrazinecarboxamide.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1965, v. 120, n. 2, p. 364, doi. 10.3181/00379727-120-30538
By:
- Glitzer, M. S.;
- Steelman, S. L.
Publication type:
Article
Effect of Hypothalamic Extracts on Release of Growth Hormone in vitro∗.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1965, v. 119, n. 1, p. 208, doi. 10.3181/00379727-119-30138
By:
- Schally, Andrew V.;
- Steelman, Sanford L.;
- Bowers, Cyril Y.
Publication type:
Article
An Improved in vitro Method for Determination of Serum “Insulin-Like” Activity.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1960, v. 105, n. 3, p. 595, doi. 10.3181/00379727-105-26189
By:
- Steelman, Sanford L.;
- Oslapas, Raymond;
- Busch, Robert D.
Publication type:
Article
Adrenocorticotropic Activity of Alpha Melanocyte Stimulating Hormone (α-MSH).∗.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1959, v. 101, n. 4, p. 600, doi. 10.3181/00379727-101-25031
By:
- Steelman, Sanford L.;
- Guillemin, Roger
Publication type:
Article
Purification of Human Pituitary Follicle Stimulating (FSH) and Luteinizing (LH) Hormones.∗.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1959, v. 101, n. 3, p. 452, doi. 10.3181/00379727-101-24976
By:
- Steelman, Sanford L.;
- Segaloff, Albert;
- Andersen, Richard N.
Publication type:
Article
Occurrence of Melanocyte Stimulating Hormone (MSH) in a Transplantable Pituitary Tumor.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1956, v. 92, n. 2, p. 392, doi. 10.3181/00379727-92-22488
By:
- Steelman, Sanford L.;
- Kelly, Thomas L.;
- Norgello, Haralds;
- Weber, G. F.
Publication type:
Article
Fractionation of the Swine Follicle Stimulating Hormone.
Published in:
Proceedings of the Society for Experimental Biology & Medicine, 1953, v. 82, n. 4, p. 645, doi. 10.3181/00379727-82-20205
By:
- Steelman, Sanford L.;
- Lamont, William A.;
- Dittman, William A.;
- Hawrylewicz, Ervin J.
Publication type:
Article
GROWTH HORMONE-RELEASING FACTOR (GRF): PHYSIOLOGICAL AND BIOCHEMICAL STUDIES WITH GRF PREPARATIONS OF BOVINE AND PORCINE ORIGIN<sup>*</sup>.
Published in:
Annals of the New York Academy of Sciences, 1968, v. 148, n. 2, p. 372, doi. 10.1111/j.1749-6632.1968.tb20364.x
By:
- Schally, A. V.;
- Müller., E. E.;
- Arimura, A.;
- Saito, T.;
- Sawano, S.;
- Bowers, C. Y.;
- Steelman, S. L.
Publication type:
Article
Purification of Human Growth Hormone on 'Sephadex G-200'.
Published in:
Nature, 1963, v. 197, n. 4873, p. 1206, doi. 10.1038/1971206a0
By:
- REISFELD, RALPH A.;
- HALLOWS, BARBARA G.;
- WILLIAMS, DONALD E.;
- BRINK, NORMAN G.;
- STEELMAN, SANFORD L.
Publication type:
Article
Before the Religious Right: Liberal Protestants, Human Rights, and the Polarization of the United States: Liberal Protestants, Human Rights, and the Polarization of the United States.
Published in:
American Religion (2643-9255), 2023, v. 4, n. 2, p. 151, doi. 10.2979/amr.2023.a896089
By:
- Steelman, Austin L.
Publication type:
Article
How do mothers' childrearing histories, stress and parenting affect children's behavioural outcomes?
Published in:
2002
By:
- Assel MA;
- Landry SH;
- Swank PR;
- Steelman L;
- Miller-Loncar C;
- Smith KE
Publication type:
Journal Article

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