Works matching AU Steeghs, Neeltje

Results: 97

Phase I Study of Sorafenib Combined with Gemcitabine and Carboplatin in Patients with Advanced Solid Tumors.

Published in:

Oncology & Therapy, 2025, v. 13, n. 2, p. 465, doi. 10.1007/s40487-025-00340-8

By:

Voogd, Daphne W. M.;
Lucassen, Merel J. J.;
van der Noll, Ruud;
Zielhuis, Sybrand W. J.;
Boss, David;
Beijnen, Jos H.;
Rosing, Hilde;
Tibben, Matthijs;
Huitema, Alwin D. R.;
Schellens, Jan H. M.;
Steeghs, Neeltje

Publication type:

Article

Correction to: Therapeutic drug monitoring of oral targeted antineoplastic drugs.

Published in:

2021

By:

Mueller-Schoell, Anna;
Groenland, Stefanie L.;
Scherf-Clavel, Oliver;
van Dyk, Madelé;
Huisinga, Wilhelm;
Michelet, Robin;
Jaehde, Ulrich;
Steeghs, Neeltje;
Huitema, Alwin D. R.;
Kloft, Charlotte

Publication type:

Correction Notice

Therapeutic drug monitoring of oral targeted antineoplastic drugs.

Published in:

European Journal of Clinical Pharmacology, 2021, v. 77, n. 4, p. 441, doi. 10.1007/s00228-020-03014-8

By:

Mueller-Schoell, Anna;
Groenland, Stefanie L.;
Scherf-Clavel, Oliver;
van Dyk, Madelé;
Huisinga, Wilhelm;
Michelet, Robin;
Jaehde, Ulrich;
Steeghs, Neeltje;
Huitema, Alwin D.R.;
Kloft, Charlotte

Publication type:

Article

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

Published in:

European Journal of Clinical Pharmacology, 2020, v. 76, n. 8, p. 1075, doi. 10.1007/s00228-020-02888-y

By:

Roosendaal, Jeroen;
Groenland, Stefanie L.;
Rosing, Hilde;
Lucas, Luc;
Venekamp, Nikkie;
Nuijen, Bastiaan;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Steeghs, Neeltje

Publication type:

Article

Individualized dosing of oral targeted therapies in oncology is crucial in the era of precision medicine.

Published in:

European Journal of Clinical Pharmacology, 2019, v. 75, n. 9, p. 1309, doi. 10.1007/s00228-019-02704-2

By:

Groenland, Stefanie L.;
Mathijssen, Ron H. J.;
Beijnen, Jos H.;
Huitema, Alwin D. R.;
Steeghs, Neeltje

Publication type:

Article

Improved Efficacy of First-Line Imatinib in Advanced Gastrointestinal Stromal Tumors (GIST): The Dutch GIST Registry Data.

Published in:

Targeted Oncology, 2023, v. 18, n. 3, p. 415, doi. 10.1007/s11523-023-00960-y

By:

Mohammadi, Mahmoud;
IJzerman, Nikki S.;
Hollander, Dide den;
Bleckman, Roos F.;
Oosten, Astrid W.;
Desar, Ingrid M. E.;
Reyners, An K. L.;
Steeghs, Neeltje;
Gelderblom, Hans

Publication type:

Article

Dutch Gastrointestinal Stromal Tumor (GIST) Registry Data Comparing Sunitinib with Imatinib Dose Escalation in Second-Line Advanced Non-KIT Exon 9 Mutated GIST Patients.

Published in:

Targeted Oncology, 2022, v. 17, n. 6, p. 627, doi. 10.1007/s11523-022-00926-6

By:

Mohammadi, Mahmoud;
Jansen-Werkhoven, Thekla M.;
Ijzerman, Nikki S.;
den Hollander, Dide;
Bleckman, Roos F.;
Oosten, Astrid W.;
Desar, Ingrid M. E.;
Reyners, An K. L.;
Steeghs, Neeltje;
Gelderblom, Hans

Publication type:

Article

Randomized, Open-Label, Crossover Studies Evaluating the Effect of Food and Liquid Formulation on the Pharmacokinetics of the Novel Focal Adhesion Kinase (FAK) Inhibitor BI 853520.

Published in:

2019

By:

Verheijen, Remy B.;
van der Biessen, Diane A. J.;
Hotte, Sebastien J.;
Siu, Lillian L.;
Spreafico, Anna;
de Jonge, Maja J. A.;
Pronk, Linda C.;
De Vos, Filip Y. F. L.;
Schnell, David;
Hirte, Hal W.;
Steeghs, Neeltje;
Lolkema, Martijn P.

Publication type:

journal article

Phase I Study of BI 853520, an Inhibitor of Focal Adhesion Kinase, in Patients with Advanced or Metastatic Nonhematologic Malignancies.

Published in:

2019

By:

de Jonge, Maja J. A.;
Steeghs, Neeltje;
Lolkema, Martijn P.;
Hotte, Sebastien J.;
Hirte, Hal W.;
van der Biessen, Diane A. J.;
Abdul Razak, Albiruni R.;
De Vos, Filip Y. F. L.;
Verheijen, Remy B.;
Schnell, David;
Pronk, Linda C.;
Jansen, Monique;
Siu, Lillian L.

Publication type:

journal article

Referral patterns of GIST patients: data from a nationwide study.

Published in:

Acta Oncologica, 2024, v. 63, n. 1, p. 28, doi. 10.2340/1651-226X.2024.23722

By:

Roets, Evelyne;
Ijzerman, Nikki S.;
Ho, Vincent K. Y.;
Desar, Ingrid M. E.;
Reyners, Anna K. L.;
Gelderblom, Hans;
Grünhagen, Dirk J.;
van Etten, Boudewijn;
van Houdt, Winan J.;
van der Graaf, Winette T. A.;
Steeghs, Neeltje

Publication type:

Article

The association of having a monitoring or blunting coping style with psychological distress, health-related quality of life and satisfaction with healthcare in gastrointestinal stromal tumour (GIST) patients.

Published in:

Acta Oncologica, 2023, v. 62, n. 12, p. 1616, doi. 10.1080/0284186X.2023.2269302

By:

van de Wal, Deborah;
van Doorn, Britt;
den Hollander, Dide;
Desar, Ingrid M. E.;
Gelderblom, Hans;
Oosten, Astrid W.;
Reyners, Anna K. L.;
Steeghs, Neeltje;
van der Graaf, Winette T. A.;
Husson, Olga

Publication type:

Article

A phase II study on the neo-adjuvant combination of pazopanib and radiotherapy in patients with high-risk, localized soft tissue sarcoma.

Published in:

Acta Oncologica, 2021, v. 60, n. 12, p. 1557, doi. 10.1080/0284186X.2021.1971294

By:

van Meekeren, Milan;
Bovee, Judith V. M. G.;
van Coevorden, Frits;
van Houdt, Winan;
Schrage, Yvonne;
Koenen, Anne Miek;
Miah, Aisha B.;
Zaidi, Shane;
Hayes, Andrew J.;
Thway, Khin;
Krol, Stijn;
Fiocco, Marta;
Gelderblom, Hans;
Steeghs, Neeltje;
Haas, Rick L.

Publication type:

Article

A phase I study on the combination of neoadjuvant radiotherapy plus pazopanib in patients with locally advanced soft tissue sarcoma of the extremities.

Published in:

Acta Oncologica, 2015, v. 54, n. 8, p. 1195, doi. 10.3109/0284186X.2015.1037404

By:

Haas, Rick L. M.;
Gelderblom, Hans;
Sleijfer, Stefan;
van Boven, Hester H.;
Scholten, Astrid;
Dewit, Luc;
Borst, Gerben;
van der Hage, Jos;
Kerst, J. Martijn;
Nout, Remi A.;
Hartgrink, Henk H.;
de Pree, Ilse;
Verhoef, Cornelis;
Steeghs, Neeltje;
van Coevorden, Frits

Publication type:

Article

Sample Bias in Web-Based Patient-Generated Health Data of Dutch Patients With Gastrointestinal Stromal Tumor:Survey Study.

Published in:

JMIR Formative Research, 2022, v. 6, n. 12, p. 1, doi. 10.2196/36755

By:

Dirkson, Anne;
Hollander, Dide den;
Verberne, Suzan;
Desar, Ingrid;
Husson, Olga;
van der Graaf, Winette T. A.;
Oosten, Astrid;
Reyners, Anna K. L.;
Steeghs, Neeltje;
van Loon, Wouter;
van Oortmerssen, Gerard;
Gelderblom, Hans;
Kraaij, Wessel

Publication type:

Article

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

Published in:

Sarcoma, 2019, p. 1, doi. 10.1155/2019/3234205

By:

Verboom, Michiel C.;
Gelderblom, Hans;
Kerst, J. Martijn;
Steeghs, Neeltje;
Reyners, Anna K. L.;
Sleijfer, Stefan;
van der Graaf, Winette T. A.;
van den Hout, Wilbert B.

Publication type:

Article

Outcome of Nonsurgical Management of Extra-Abdominal, Trunk, and Abdominal Wall Desmoid-Type Fibromatosis: A Population-Based Study in the Netherlands.

Published in:

Sarcoma, 2018, p. 1, doi. 10.1155/2018/5982575

By:

van Broekhoven, Danique L. M.;
Verschoor, Arie J.;
van Dalen, Thijs;
Grünhagen, Dirk J.;
den Bakker, Michael A.;
Gelderblom, Hans;
Bovee, Judith V. M. G.;
Haas, Rick L. M.;
Bonenkamp, Han J.;
van Coevorden, Frits;
ten Oever, Diederik;
van der Graaf, Winette T. A.;
Flucke, Uta E.;
Pras, Elisabeth;
Reyners, Anna K. L.;
Westermann, Anneke M.;
Oldenburger, Foppe;
Verhoef, Cornelis;
Steeghs, Neeltje

Publication type:

Article

Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma.

Published in:

Cancer Chemotherapy & Pharmacology, 2025, v. 95, n. 1, p. 1, doi. 10.1007/s00280-024-04746-5

By:

Meertens, Marinda;
Giraud, Eline L.;
Hassan, Esbar;
Zielhuis, Sybrand W.J.;
Snels, Tiemen T.;
Desar, Ingrid M. E.;
Walraven, Janneke E. W.;
Wilgenhof, Sofie;
van Thienen, Johannes V.;
de Boer, Jan Paul;
Steeghs, Neeltje;
van Erp, Nielka P.;
Huitema, Alwin D. R.

Publication type:

Article

A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure–response relationships: a proof-of-concept study with alectinib.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 3, p. 453, doi. 10.1007/s00280-024-04698-w

By:

Lin, Lishi;
van der Noort, Vincent;
Steeghs, Neeltje;
Ruiter, Gerrina;
Beijnen, Jos H.;
Huitema, Alwin D. R.

Publication type:

Article

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 94, n. 1, p. 25, doi. 10.1007/s00280-024-04640-0

By:

Lau, Cedric;
Mohmaed Ali, Ma Ida;
Lin, Lishi;
van Balen, Dorieke E. M.;
Jacobs, Bart A. W.;
Nuijen, Bastiaan;
Smeenk, Robert M.;
Steeghs, Neeltje;
Huitema, Alwin D. R.

Publication type:

Article

Are novel oral oncolytics underdosed in obese patients?

Published in:

Cancer Chemotherapy & Pharmacology, 2024, v. 93, n. 2, p. 129, doi. 10.1007/s00280-023-04601-z

By:

Lin, Lishi;
van der Meer, Ellen K. O.;
Steeghs, Neeltje;
Beijnen, Jos H.;
Huitema, Alwin D. R.

Publication type:

Article

Is age just a number? A population pharmacokinetic study of gemcitabine.

Published in:

Cancer Chemotherapy & Pharmacology, 2022, v. 89, n. 5, p. 697, doi. 10.1007/s00280-022-04431-5

By:

Boosman, René J.;
Crombag, Marie-Rose B. S.;
van Erp, Nielka P.;
Beijnen, Jos H.;
Steeghs, Neeltje;
Huitema, Alwin D. R.

Publication type:

Article

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

Published in:

2020

By:

Huijberts, Sanne C. F. A.;
van Geel, Robin M. J. M.;
van Brummelen, Emilie M. J.;
Opdam, Frans L.;
Marchetti, Serena;
Steeghs, Neeltje;
Pulleman, Saskia;
Thijssen, Bas;
Rosing, Hilde;
Monkhorst, Kim;
Huitema, Alwin D. R.;
Beijnen, Jos H.;
Bernards, René;
Schellens, Jan H. M.

Publication type:

journal article

Neoadjuvant Imatinib in Locally Advanced Gastrointestinal Stromal Tumors (GISTs) is Effective and Safe: Results from a Prospective Single-Center Study with 108 Patients.

Published in:

Annals of Surgical Oncology: An Oncology Journal for Surgeons, 2023, v. 30, n. 13, p. 8660, doi. 10.1245/s10434-023-14346-x

By:

van der Burg, Stijn J. C.;
van de Wal, Deborah;
Roets, Evelyne;
Steeghs, Neeltje;
van Sandick, Johanna W.;
Kerst, Martijn;
van Coevorden, Frits;
Hartemink, Koen J.;
Veenhof, Xander A. A. F. A.;
Koenen, Anne Miek;
Ijzerman, Nikki;
van der Graaf, Winette T. A.;
Schrage, Yvonne M.;
van Houdt, Winan J.

Publication type:

Article

Imatinib-induced agranulocytosis in patients with gastrointestinal stromal tumors.

Published in:

Journal of Clinical Pharmacology, 2015, v. 55, n. 8, p. 920, doi. 10.1002/jcph.498

By:

Farag, Sheima;
Verschoor, Arjan J.;
Bosma, Jacob W.;
Gelderblom, Hans;
Kerst, J. Martijn;
Sleijfer, Stefan;
Steeghs, Neeltje

Publication type:

Article

Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and <sup>11</sup>C-Erlotinib PET.

Published in:

Journal of Nuclear Medicine, 2018, v. 59, n. 6, p. 973, doi. 10.2967/jnumed.117.195800

By:

Verheijen, Remy B.;
Yaqub, Maqsood;
Sawicki, Emilia;
van Tellingen, Olaf;
Lammertsma, Adriaan A.;
Nuijen, Bastiaan;
Schellens, Jan H. M.;
Beijnen, Jos H.;
Huitema, Alwin D. R.;
Hendrikse, N. Harry;
Steeghs, Neeltje

Publication type:

Article

Early Evaluation of Response Using <sup>18</sup>F-FDG PET Influences Management in Gastrointestinal Stromal Tumor Patients Treated with Neoadjuvant Imatinib.

Published in:

Journal of Nuclear Medicine, 2018, v. 59, n. 2, p. 194, doi. 10.2967/jnumed.117.196642

By:

Farag, Sheima;
de Geus-Oei, Lioe-Fee;
van der Graaf, Winette T.;
van Coevorden, Frits;
Grunhagen, Dirk;
Reyners, Anna K. L.;
Boonstra, Pieter A.;
Desar, Ingrid;
Gelderblom, Hans;
Steeghs, Neeltje

Publication type:

Article

Liquid Biopsies in Sarcoma Clinical Practice: Where Do We Stand?

Published in:

Biomedicines, 2021, v. 9, n. 10, p. 1315, doi. 10.3390/biomedicines9101315

By:

van der Laan, Pia;
van Houdt, Winan J.;
van den Broek, Daan;
Steeghs, Neeltje;
van der Graaf, Winette T. A.

Publication type:

Article

Driver mutations occur frequently in metastases of well‐differentiated small intestine neuroendocrine tumours.

Published in:

Histopathology, 2021, v. 78, n. 4, p. 556, doi. 10.1111/his.14252

By:

Samsom, Kris G;
Levy, Sonja;
Veenendaal, Linde M;
Roepman, Paul;
Kodach, Liudmila L;
Steeghs, Neeltje;
Valk, Gerlof D;
Wouter Dercksen, M;
Kuhlmann, Koert F D;
Verbeek, Wieke H M;
Meijer, Gerrit A;
Tesselaar, Margot E T;
Berg, José G

Publication type:

Article

Individualized Dosing Patterns in the Treatment of Older Patients with Gastrointestinal Stromal Tumors: Results of a Registry-Based Observational National Cohort Study Including 871 Patients.

Published in:

Drugs & Aging, 2024, v. 41, n. 2, p. 165, doi. 10.1007/s40266-023-01084-8

By:

Bleckman, Roos F.;
Broekman, K. Esther;
Roets, Evelyne;
Mohammadi, Mohammed;
Desar, Ingrid M. E.;
Gelderblom, Hans;
Mathijssen, Ron H. J.;
Steeghs, Neeltje;
de Graeff, Pauline;
Reyners, Anna K. L.

Publication type:

Article

Author Correction: Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.

Published in:

2021

By:

Mendelaar, Pauline A. J.;
Smid, Marcel;
van Riet, Job;
Angus, Lindsay;
Labots, Mariette;
Steeghs, Neeltje;
Hendriks, Mathijs P.;
Cirkel, Geert A.;
van Rooijen, Johan M.;
Ten Tije, Albert J.;
Lolkema, Martijn P.;
Cuppen, Edwin;
Sleijfer, Stefan;
Martens, John W. M.;
Wilting, Saskia M.

Publication type:

Correction Notice

Whole genome sequencing of metastatic colorectal cancer reveals prior treatment effects and specific metastasis features.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20887-6

By:

Mendelaar, Pauline A. J.;
Smid, Marcel;
van Riet, Job;
Angus, Lindsay;
Labots, Mariette;
Steeghs, Neeltje;
Hendriks, Mathijs P.;
Cirkel, Geert A.;
van Rooijen, Johan M.;
Ten Tije, Albert J.;
Lolkema, Martijn P.;
Cuppen, Edwin;
Sleijfer, Stefan;
Martens, John W. M.;
Wilting, Saskia M.

Publication type:

Article

The Prediagnostic General Practitioners' Pathway of Gastrointestinal Stromal Tumor Patients: A Real-World Data Study.

Published in:

Cancers, 2025, v. 17, n. 9, p. 1391, doi. 10.3390/cancers17091391

By:

Holthuis, Emily I.;
Slijkhuis, Verena;
van der Graaf, Winette T. A.;
Drabbe, Cas;
van Houdt, Winan J.;
Schrage, Yvonne M.;
Olde Hartman, Tim C.;
Uijen, Annemarie;
Steeghs, Neeltje;
Bos, Isabelle;
Heins, Marianne;
Husson, Olga

Publication type:

Article

Impact of Mutation Profile on Outcomes of Neoadjuvant Therapy in GIST.

Published in:

Cancers, 2025, v. 17, n. 4, p. 634, doi. 10.3390/cancers17040634

By:

Mohammadi, Mahmoud;
Roets, Evelyne;
Bleckman, Roos F.;
Oosten, Astrid W.;
Grunhagen, Dirk;
Desar, Ingrid M. E.;
Bonenkamp, Han;
Reyners, Anna K. L.;
van Etten, Boudewijn;
Hartgrink, Henk;
Fiocco, Marta;
Schrage, Yvonne;
Steeghs, Neeltje;
Gelderblom, Hans

Publication type:

Article

Genomic Alterations Associated with Estrogen Receptor Pathway Activity in Metastatic Breast Cancer Have a Differential Impact on Downstream ER Signaling.

Published in:

Cancers, 2023, v. 15, n. 17, p. 4416, doi. 10.3390/cancers15174416

By:

Angus, Lindsay;
Smid, Marcel;
Wilting, Saskia M.;
Bos, Manouk K.;
Steeghs, Neeltje;
Konings, Inge R. H. M.;
Tjan-Heijnen, Vivianne C. G.;
van Riel, Johanna M. G. H.;
van de Wouw, Agnes J.;
Cuppen, Edwin;
Lolkema, Martijn P.;
Jager, Agnes;
Sleijfer, Stefan;
Martens, John W. M.

Publication type:

Article

Framework for Implementing Individualised Dosing of Anti-Cancer Drugs in Routine Care: Overcoming the Logistical Challenges.

Published in:

Cancers, 2023, v. 15, n. 13, p. 3293, doi. 10.3390/cancers15133293

By:

van Leuven, Jason;
Evans, Simon;
Kichenadasse, Ganessan;
Steeghs, Neeltje;
Bonevski, Billie;
Mikus, Gerd;
van Dyk, Madelé

Publication type:

Article

Health-Related Quality of Life and Side Effects in Gastrointestinal Stromal Tumor (GIST) Patients Treated with Tyrosine Kinase Inhibitors: A Systematic Review of the Literature.

Published in:

Cancers, 2022, v. 14, n. 7, p. 1832, doi. 10.3390/cancers14071832

By:

van de Wal, Deborah;
Elie, Mai;
Le Cesne, Axel;
Fumagalli, Elena;
den Hollander, Dide;
Jones, Robin L.;
Marquina, Gloria;
Steeghs, Neeltje;
van der Graaf, Winette T. A.;
Husson, Olga

Publication type:

Article

Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol.

Published in:

Cancers, 2021, v. 13, n. 24, p. 6281, doi. 10.3390/cancers13246281

By:

Mc Laughlin, Anna M.;
Schmulenson, Eduard;
Teplytska, Olga;
Zimmermann, Sebastian;
Opitz, Patrick;
Groenland, Stefanie L.;
Huitema, Alwin D. R.;
Steeghs, Neeltje;
Müller, Lothar;
Fuxius, Stefan;
Illerhaus, Gerald;
Joerger, Markus;
Mayer, Frank;
Fuhr, Uwe;
Holdenrieder, Stefan;
Hempel, Georg;
Scherf-Clavel, Oliver;
Jaehde, Ulrich;
Kloft, Charlotte

Publication type:

Article

Intra-Tumoral Pharmacokinetics of Pazopanib in Combination with Radiotherapy in Patients with Non-Metastatic Soft-Tissue Sarcoma.

Published in:

Cancers, 2021, v. 13, n. 22, p. 5780, doi. 10.3390/cancers13225780

By:

Molenaar-Kuijsten, Laura;
van Meekeren, Milan;
Verheijen, Remy B.;
Bovée, Judith V. M. G.;
Fiocco, Marta;
Thijssen, Bas;
Rosing, Hilde;
Huitema, Alwin D. R.;
Miah, Aisha B.;
Gelderblom, Hans;
Haas, Rick L. M.;
Steeghs, Neeltje

Publication type:

Article

Germline Variation in PDCD1 Is Associated with Overall Survival in Patients with Metastatic Melanoma Treated with Anti-PD-1 Monotherapy.

Published in:

Cancers, 2021, v. 13, n. 6, p. 1370, doi. 10.3390/cancers13061370

By:

de With, Mirjam;
Hurkmans, Daan P.;
Oomen-de Hoop, Esther;
Lalouti, Ayoub;
Bins, Sander;
El Bouazzaoui, Samira;
van Brakel, Mandy;
Debets, Reno;
Aerts, Joachim G. J. V.;
van Schaik, Ron H. N.;
Mathijssen, Ron H. J.;
van der Veldt, Astrid A. M.;
Steeghs, Neeltje

Publication type:

Article

Neoadjuvant Systemic Treatment of Primary Angiosarcoma.

Published in:

Cancers, 2020, v. 12, n. 8, p. 2251, doi. 10.3390/cancers12082251

By:

Heinhuis, Kimberley M.;
IJzerman, Nikki S.;
van der Graaf, Winette T. A.;
Kerst, Jan Martijn;
Schrage, Yvonne;
Beijnen, Jos H.;
Steeghs, Neeltje;
van Houdt, Winan J.

Publication type:

Article

RNA-Sequencing of Tumor-Educated Platelets, a Novel Biomarker for Blood-Based Sarcoma Diagnostics.

Published in:

Cancers, 2020, v. 12, n. 6, p. 1372, doi. 10.3390/cancers12061372

By:

Heinhuis, Kimberley M.;
In 't Veld, Sjors G. J. G.;
Dwarshuis, Govert;
van den Broek, Daan;
Sol, Nik;
Best, Myron G.;
van Coevorden, Frits;
Haas, Rick L.;
Beijnen, Jos H.;
van Houdt, Winan J.;
Würdinger, Tom;
Steeghs, Neeltje

Publication type:

Article

Gastrointestinal Stromal Tumours (GIST) in Young Adult (18–40 Years) Patients: A Report from the Dutch GIST Registry.

Published in:

Cancers, 2020, v. 12, n. 3, p. 730, doi. 10.3390/cancers12030730

By:

IJzerman, Nikki S.;
Drabbe, Cas;
den Hollander, Dide;
Mohammadi, Mahmoud;
van Boven, Hester;
Desar, Ingrid M. E.;
Gelderblom, Hans;
Grünhagen, Dirk J.;
Reyners, An K. L.;
van Noesel, Max M.;
Mathijssen, Ron H. J.;
Steeghs, Neeltje;
van der Graaf, Winette T. A.

Publication type:

Article

Exposure–Response Analyses of Anaplastic Lymphoma Kinase Inhibitors Crizotinib and Alectinib in Non‐Small Cell Lung Cancer Patients.

Published in:

Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 2, p. 394, doi. 10.1002/cpt.1989

By:

Groenland, Stefanie L.;
Geel, Dieuwertje R.;
Janssen, Julie M.;
Vries, Niels;
Rosing, Hilde;
Beijnen, Jos H.;
Burgers, Jacobus A.;
Smit, Egbert F.;
Huitema, Alwin D.R.;
Steeghs, Neeltje

Publication type:

Article

Pharmacokinetic Targets for Therapeutic Drug Monitoring of Small Molecule Kinase Inhibitors in Pediatric Oncology.

Published in:

Clinical Pharmacology & Therapeutics, 2020, v. 108, n. 3, p. 494, doi. 10.1002/cpt.1808

By:

Janssen, Julie M.;
Dorlo, Thomas P. C.;
Steeghs, Neeltje;
Beijnen, Jos H.;
Hanff, Lidwien M.;
Eijkelenburg, Natasha K. A.;
Lugt, Jasper;
Zwaan, C. Michel;
Huitema, Alwin D. R.

Publication type:

Article

Practical Recommendations for Therapeutic Drug Monitoring of Kinase Inhibitors in Oncology.

Published in:

Clinical Pharmacology & Therapeutics, 2017, v. 102, n. 5, p. 765, doi. 10.1002/cpt.787

By:

Verheijen, Remy B.;
Yu, Huixin;
Schellens, Jan H.M.;
Beijnen, Jos H.;
Steeghs, Neeltje;
Huitema, Alwin D.R.

Publication type:

Article

Harnessing soft tissue sarcoma with low-dose pazopanib - a matter of blood levels.

Published in:

2018

By:

Groenland, Stefanie L.;
Katz, Daniela;
Huitema, Alwin D. R.;
Steeghs, Neeltje

Publication type:

journal article

Phase Ib/II Study of the Efficacy and Safety of Binimetinib (MEK162) Plus Panitumumab for Mutant or Wild-Type RAS Metastatic Colorectal Cancer.

Published in:

Oncologist, 2023, v. 28, n. 12, p. e1209, doi. 10.1093/oncolo/oyad210

By:

Van Cutsem, Eric;
Yaeger, Rona;
Delord, Jean-Pierre;
Tabernero, Josep;
Siu, Lillian L;
Ducreux, Michel;
Siena, Salvatore;
Elez, Elena;
Kasper, Stefan;
Zander, Thomas;
Steeghs, Neeltje;
Murphy, Danielle;
Edwards, Michelle;
Wainberg, Zev A

Publication type:

Article

Phase I Study of Afatinib and Selumetinib in Patients with KRAS‐Mutated Colorectal, Non‐Small Cell Lung, and Pancreatic Cancer.

Published in:

Oncologist, 2021, v. 26, n. 4, p. 290, doi. 10.1002/onco.13631

By:

Brummelen, Emilie M.J.;
Huijberts, Sanne;
Herpen, Carla;
Desar, Ingrid;
Opdam, Frans;
Geel, Robin;
Marchetti, Serena;
Steeghs, Neeltje;
Monkhorst, Kim;
Thijssen, Bas;
Rosing, Hilde;
Huitema, Alwin;
Beijnen, Jos;
Bernards, Rene;
Schellens, Jan

Publication type:

Article

Therapeutic drug monitoring to personalize dosing of imatinib, sunitinib, and pazopanib: A mixed methods study on barriers and facilitators.

Published in:

Cancer Medicine, 2023, v. 12, n. 22, p. 21041, doi. 10.1002/cam4.6663

By:

Westerdijk, Kim;
Steeghs, Neeltje;
Tacke, Casper S. J.;
van der Graaf, Winette T. A.;
van Erp, Nielka P.;
van Oortmerssen, Gerard;
Hermens, Rosella P. M. G.;
Desar, Ingrid M. E.

Publication type:

Article

Worse capecitabine treatment outcome in patients with a low skeletal muscle mass is not explained by altered pharmacokinetics.

Published in:

Cancer Medicine, 2021, v. 10, n. 14, p. 4781, doi. 10.1002/cam4.4038

By:

Molenaar‐Kuijsten, Laura;
Jacobs, Bart Albertus Wilhelmus;
Kurk, Sophie Alberdine;
May, Anne Maria;
Dorlo, Thomas Petrus Catharina;
Beijnen, Jacob Hendrik;
Steeghs, Neeltje;
Huitema, Alwin Dagmar Redmar

Publication type:

Article