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Tumor necrosis factor-mediated disposition of infliximab in ulcerative colitis patients.
- Published in:
- Journal of Pharmacokinetics & Pharmacodynamics, 2019, v. 46, n. 6, p. 543, doi. 10.1007/s10928-019-09652-5
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- Article
Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.
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- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 9, p. 543, doi. 10.1002/bdd.2106
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- Article
Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.
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- Biopharmaceutics & Drug Disposition, 2017, v. 38, n. 6, p. 373, doi. 10.1002/bdd.2075
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- Article
SYSTEMS PHARMACOLOGY ANALYSIS OF THE Aβ OLIGOMER RESPONSE FOLLOWING BACE1 INHIBITION: EVIDENCE FOR SECOND-ORDER Aβ42 OLIGOMERIZATION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P281, doi. 10.1016/j.jalz.2017.06.175
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- Article
RESILIENCE MECHANISM OF THE AMYLOID PRECURSOR PROTEIN (APP) PATHWAY REVEALED BY SYSTEMS PHARMACOLOGY MODELING FOLLOWING β- AND GAMMA-SECRETASE INHIBITION.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P630, doi. 10.1016/j.jalz.2017.06.715
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- Article
An integrated mechanistic model to interrelate CSF Aβ40, Aβ42, sAPPβ and sAPPα response to β- and γ-secretase inhibitors in rhesus monkey
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- 2012
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- Publication type:
- Abstract
Toward the prediction of CNS drug-effect profiles in physiological and pathological conditions using microdialysis and mechanism-based pharmacokinetic-pharmacodynamic modeling.
- Published in:
- AAPS Journal, 2005, v. 7, n. 3, p. E532, doi. 10.1208/aapsj070354
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- Article