Works by Steeg, Patricia S.

Results: 43

Brain Metastases of Breast Cancer.

Published in:

Breast Disease, 2007, v. 26, n. 1, p. 139, doi. 10.3233/BD-2007-26112

By:

Palmieri, Diane;
Smith, Quentin R.;
Lockman, Paul R.;
Bronder, Julie;
Gril, Brunilde;
Chambers, Ann F.;
Weil, Robert J.;
Steeg, Patricia S.

Publication type:

Article

Breast Cancer Advocacy and Basic Research: A Scientist's Perspective.

Published in:

Breast Disease, 1998, v. 10, n. 5/6, p. 47, doi. 10.3233/BD-1998-105-607

By:

Steeg, Patricia S.

Publication type:

Article

Expression of the extracellular matrix molecule thrombospondin inversely correlates with malignant progression in melanoma, lung and breast carcinoma cell lines.

Published in:

International Journal of Cancer, 1994, v. 59, n. 2, p. 191, doi. 10.1002/ijc.2910590209

By:

Zabrenetzky, Vivian;
Harris, Curtis C.;
Steeg, Patricia S.;
Roberts, David D.

Publication type:

Article

Roadblocks to translational advances on metastasis research.

Published in:

Nature Medicine, 2013, v. 19, n. 9, p. 1104, doi. 10.1038/nm.3327

By:

Brabletz, Thomas;
Lyden, David;
Steeg, Patricia S;
Werb, Zena

Publication type:

Article

Tumor metastasis: mechanistic insights and clinical challenges.

Published in:

Nature Medicine, 2006, v. 12, n. 8, p. 895, doi. 10.1038/nm1469

By:

Steeg, Patricia S.

Publication type:

Article

Angiogenesis inhibitors: motivators of metastasis?

Published in:

Nature Medicine, 2003, v. 9, n. 7, p. 822, doi. 10.1038/nm0703-822

By:

Steeg, Patricia S

Publication type:

Article

The role of MMP-1 in breast cancer growth and metastasis to the brain in a xenograft model.

Published in:

BMC Cancer, 2012, v. 12, n. 1, p. 583, doi. 10.1186/1471-2407-12-583

By:

Liu, Hui;
Kato, Yukinari;
Erzinger, Stephanie A.;
Kiriakova, Galina A.;
Qian, Yongzhen;
Palmieri, Diane;
Steeg, Patricia S.;
Price, Janet E.

Publication type:

Article

Nm23/nucleoside diphosphate kinase: Toward a structural and biochemical understanding of its biological functions.

Published in:

BioEssays, 1995, v. 17, n. 1, p. 53, doi. 10.1002/bies.950170111

By:

De La Rosa, Abel;
Steeg, Patricia S.;
Williams, Roger L.

Publication type:

Article

Massively Parallel Sequencing Reveals an Accumulation of <i>De Novo</i> Mutations and an Activating Mutation of <i>LPAR1</i> in a Patient with Metastatic Neuroblastoma.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077731

By:

Wei, Jun S.;
Johansson, Peter;
Chen, Li;
Song, Young K.;
Tolman, Catherine;
Li, Samuel;
Hurd, Laura;
Patidar, Rajesh;
Wen, Xinyu;
Badgett, Thomas C.;
Cheuk, Adam T. C.;
Marshall, Jean-Claude;
Steeg, Patricia S.;
Vaqué Díez, José P.;
Yu, Yanlin;
Gutkind, J. Silvio;
Khan, Javed

Publication type:

Article

Inhibition of Type I Insulin-Like Growth Factor Receptor Signaling Attenuates the Development of Breast Cancer Brain Metastasis.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073406

By:

Saldana, Sandra M.;
Lee, Heng-Huan;
Lowery, Frank J.;
Khotskaya, Yekaterina B.;
Xia, Weiya;
Zhang, Chenyu;
Chang, Shih-Shin;
Chou, Chao-Kai;
Steeg, Patricia S.;
Yu, Dihua;
Hung, Mien-Chie

Publication type:

Article

The B-Raf Status of Tumor Cells May Be a Significant Determinant of Both Antitumor and Anti-Angiogenic Effects of Pazopanib in Xenograft Tumor Models.

Published in:

PLoS ONE, 2011, v. 6, n. 10, p. 1, doi. 10.1371/journal.pone.0025625

By:

Gril, Brunilde;
Palmieri, Diane;
Yong Qian;
Anwar, Talha;
Ileva, Lilia;
Bernardo, Marcelino;
Choyke, Peter;
Liewehr, David J.;
Steinberg, Seth M.;
Steeg, Patricia S.

Publication type:

Article

Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2012, v. 104, n. 17, p. 1306, doi. 10.1093/jnci/djs319

By:

Marshall, Jean-Claude A.;
Collins, Joshua W.;
Nakayama, Joji;
Horak, Christine E.;
Liewehr, David J.;
Steinberg, Seth M.;
Albaugh, Mary;
Vidal-Vanaclocha, Fernando;
Palmieri, Diane;
Barbier, Maryse;
Murone, Maximilien;
Steeg, Patricia S.

Publication type:

Article

New approaches to proteomic analysis of breast cancer.

Published in:

Proteomics, 2001, v. 1, n. 10, p. 1205, doi. 10.1002/1615-9861(200110)1:10<1205::AID-PROT1205>3.0.CO;2-X

By:

Wulfkuhle, Julia D.;
McLean, Kelley C.;
Paweletz, Cloud P.;
Sgroi, Dennis C.;
Trock, Bruce J.;
Steeg, Patricia S.;
Petricoin III, Emanuel F.

Publication type:

Article

Effect of Lapatinib on the Outgrowth of Metastatic Breast Cancer Cells to the Brain.

Published in:

JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 15, p. 1092, doi. 10.1093/jnci/djn216

By:

Gril, Brunilde;
Palmieri, Diane;
Bronder, Julie L.;
Herring, Jeanne M.;
Vega-Valle, Eleazar;
Feigenbaum, Lionel;
Liewehr, David J.;
Steinberg, Seth M.;
Merino, Maria J.;
Rubin, Stephen D.;
Steeg, Patricia S.

Publication type:

Article

Medroxyprogesterone Acetate Elevation of Nm23-H1 Metastasis Suppressor Expression in Hormone Receptor-Negative Breast Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2005, v. 97, n. 9, p. 632, doi. 10.1093/jnci/dji111

By:

Palmieri, Diane;
Halverson, Douglas O.;
Ouatas, Taoufik;
Horak, Christine E.;
Salerno, Massimiliano;
Johnson, Jennifer;
Figg, W. Douglas;
Hollingshead, Melinda;
Hursting, Stephen;
Berrigan, David;
Steinberg, Seth M.;
Merino, Maria J.;
Steeg, Patricia S.

Publication type:

Article

Perspectives on classic article: metastasis suppressor genes.

Published in:

2004

By:

Steeg, Patricia S

Publication type:

journal article

Collapsin response mediator protein-1: a lung cancer invasion suppressor gene with nerve.

Published in:

2001

By:

Steeg, Patricia S.;
Steeg, P S

Publication type:

commentary

Inhibition of cyclin D expression in human breast carcinoma cells by retinoids in vitro.

Published in:

Oncogene, 1997, v. 15, n. 1, p. 107, doi. 10.1038/sj.onc.1201142

By:

Zhou, Qun;
Stetler-Stevenson, Maryalice;
Steeg, Patricia S

Publication type:

Article

The role of metastasis suppressor genes in metastatic dormancy.

Published in:

APMIS, 2008, v. 116, n. 7/8, p. 586, doi. 10.1111/j.1600-0463.2008.01027.x

By:

HORAK, CHRISTINE E.;
JONG HEUN LEE;
MARSHALL, JEAN-CLAUDE;
SHREEVE, S. MARTIN;
STEEG, PATRICIA S.

Publication type:

Article

Nm23-H1 Metastasis Suppressor Expression Level Influences the Binding Properties, Stability, and Function of the Kinase Suppressor of Ras1 (KSR1) Erk Scaffold in Breast Carcinoma Cells.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 4, p. 1379, doi. 10.1128/MCB.25.4.1379-1388.2005

By:

Salerno, Massimiliano;
Palmieri, Diane;
Bouadis, Amina;
Halverson, Douglas;
Steeg, Patricia S.

Publication type:

Article

The murine metastatic microenvironment of experimental brain metastases of breast cancer differs by host age in vivo: a proteomic study.

Published in:

Clinical & Experimental Metastasis, 2024, v. 41, n. 3, p. 229, doi. 10.1007/s10585-023-10233-7

By:

Hunt, Allison L.;
Khan, Imran;
Wu, Alex M. L.;
Makohon-Moore, Sasha C.;
Hood, Brian L.;
Conrads, Kelly A.;
Abulez, Tamara;
Ogata, Jonathan;
Mitchell, Dave;
Gist, Glenn;
Oliver, Julie;
Wei, Debbie;
Chung, Monika A.;
Rahman, Samiur;
Bateman, Nicholas W.;
Zhang, Wei;
Conrads, Thomas P.;
Steeg, Patricia S.

Publication type:

Article

Metastasis suppressor NME1 in exosomes or liposomes conveys motility and migration inhibition in breast cancer model systems.

Published in:

Clinical & Experimental Metastasis, 2022, v. 39, n. 5, p. 815, doi. 10.1007/s10585-022-10182-7

By:

Khan, Imran;
Gril, Brunilde;
Hoshino, Ayuko;
Yang, Howard H.;
Lee, Maxwell P.;
Difilippantonio, Simone;
Lyden, David C.;
Steeg, Patricia S.

Publication type:

Article

In vivo MRI of cancer cell fate at the single-cell level in a mouse model of breast cancer metastasis to the brain.

Published in:

Magnetic Resonance in Medicine, 2006, v. 56, n. 5, p. 1001, doi. 10.1002/mrm.21029

By:

Heyn, Chris;
Ronald, John A.;
Ramadan, Soha S.;
Snir, Jonatan A.;
Barry, Andrea M.;
MacKenzie, Lisa T.;
Mikulis, David J.;
Palmieri, Diane;
Bronder, Julie L.;
Steeg, Patricia S.;
Yoneda, Toshiyuki;
MacDonald, Ian C.;
Chambers, Ann F.;
Rutt, Brian K.;
Foster, Paula J.

Publication type:

Article

Analysis of breast cancer in young women in the Department of Defense (DOD) database.

Published in:

Breast Cancer Research & Treatment, 2018, v. 168, n. 2, p. 501, doi. 10.1007/s10549-017-4615-8

By:

Zimmer, Alexandra S.;
Zhu, Kangmin;
Steeg, Patricia S.;
Wu, Alex;
Gatti-Mays, Margaret E.;
Soltani, Sanaz;
Perkins, Jeremy G.;
Shao, Stephanie;
Brown, Derek;
Georg, Matthew;
Hu, Hai;
Shriver, Craig D.;
Lipkowitz, Stanley

Publication type:

Article

Brain metastases as preventive and therapeutic targets.

Published in:

2011

By:

Steeg, Patricia S.;
Camphausen, Kevin A.;
Smith, Quentin R.

Publication type:

journal article

Metastasis suppressors alter the signal transduction of cancer cells.

Published in:

Nature Reviews Cancer, 2003, v. 3, n. 1, p. 55, doi. 10.1038/nrc967

By:

Steeg, Patricia S.

Publication type:

Article

A BRCA1 deficient-like signature is enriched in breast cancer brain metastases and predicts DNA damage-induced poly (ADP-ribose) polymerase inhibitor sensitivity.

Published in:

2014

By:

McMullin, Ryan P;
Wittner, Ben S;
Yang, Chuanwei;
Denton-Schneider, Benjamin R;
Hicks, Daniel;
Singavarapu, Raj;
Moulis, Sharon;
Lee, Jeongeun;
Akbari, Mohammad R;
Narod, Steven A;
Aldape, Kenneth D;
Steeg, Patricia S;
Ramaswamy, Sridhar;
Sgroi, Dennis C

Publication type:

journal article

Combined breast ductal lavage and ductal endoscopy for the evaluation of the high-risk breast: A feasibility study.

Published in:

Journal of Surgical Oncology, 2006, v. 94, n. 7, p. 555, doi. 10.1002/jso.20650

By:

Danforth, David N.;
Abati, Andrea;
Filie, Armando;
Prindiville, Shiela A.;
Palmieri, Diane;
Simon, Richard;
Ried, Thomas;
Steeg, Patricia S.

Publication type:

Article

Cancer: Micromanagement of metastasis.

Published in:

Nature, 2007, v. 449, n. 7163, p. 671, doi. 10.1038/449671a

By:

Steeg, Patricia S.

Publication type:

Article

Cancer biology: Emissaries set up new sites.

Published in:

Nature, 2005, v. 438, n. 7069, p. 750, doi. 10.1038/438750b

By:

Steeg, Patricia S.

Publication type:

Article

Endocytosis: a pivotal pathway for regulating metastasis.

Published in:

2021

By:

Khan, Imran;
Steeg, Patricia S.

Publication type:

journal article

In vivo single scan detection of both iron-labeled cells and breast cancer metastases in the mouse brain using balanced steady-state free precession imaging at 1.5 T.

Published in:

Journal of Magnetic Resonance Imaging, 2011, v. 34, n. 1, p. 231, doi. 10.1002/jmri.22593

By:

Ribot, Emeline J.;
Martinez-Santiesteban, Francisco M.;
Simedrea, Carmen;
Steeg, Patricia S.;
Chambers, Ann F.;
Rutt, Brian K.;
Foster, Paula J.

Publication type:

Article

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer.

Published in:

2019

By:

Greer, Yoshimi Endo;
Gilbert, Samuel F.;
Gril, Brunilde;
Narwal, Rajesh;
Peacock Brooks, Danielle L.;
Tice, David A.;
Steeg, Patricia S.;
Lipkowitz, Stanley

Publication type:

journal article

A perspective on the metastasis suppressor field.

Published in:

Cancer & Metastasis Reviews, 2023, v. 42, n. 4, p. 1061, doi. 10.1007/s10555-023-10131-0

By:

Khan, Imran;
Steeg, Patricia S.

Publication type:

Article

Perspective: The right trials.

Published in:

Nature, 2012, v. 485, n. 7400, p. S58, doi. 10.1038/485S58a

By:

Steeg, Patricia S.

Publication type:

Article

An added dimension: Will three-dimensional cultures improve our understanding of drug resistance?

Published in:

1994

By:

Steeg, Patricia S.;
Alley, Michael C.

Publication type:

Editorial

Metastatic Models and Molecular Genetics of Prostate Cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 1992, v. 84, n. 12, p. 914

By:

Linehan, W. Marston;
Long, John P.;
Steeg, Patricia S.;
Gnarra, James R.

Publication type:

Article

Induction of nm23 Gene Expression in Human Colonic Neoplasms and Equal Expressions in Colon Tumors of High and Low Metastatic Potential.

Published in:

JNCI: Journal of the National Cancer Institute, 1991, v. 83, n. 10, p. 712

By:

Haut, Mitchell;
Steeg, Patricia S.;
Willson, James K. V.;
Markowitz, Sanford D.

Publication type:

Article

Clues to the Function of Nm23 and Awd Proteins in Development, Signal Transduction, and Tumor Metastasis Provided by Studies of Dictyostelium discoideum.

Published in:

JNCI: Journal of the National Cancer Institute, 1990, v. 82, n. 14, p. 1170, doi. 10.1093/jnci/82.14.1170

By:

Liotta, Lance A.;
Steeg, Patricia S.

Publication type:

Article

Evidence for a Novel Gene Associated With Low Tumor Metastatic Potential2.

Published in:

JNCI: Journal of the National Cancer Institute, 1988, v. 80, n. 3, p. 200

By:

Steeg, Patricia S.;
Bevilacqua, Generoso;
Kopper, Laszlo;
Thorgeirsson, Unnur P.;
Talmadge, James E.;
Liotta, Lance A.;
Sobel, Mark E.

Publication type:

Article

Distinct uptake and elimination profiles for trastuzumab, human IgG, and biocytin-TMR in experimental HER2+ brain metastases of breast cancer.

Published in:

Neuro-Oncology, 2024, v. 26, n. 6, p. 1067, doi. 10.1093/neuonc/noae025

By:

Silvestri, Vanesa L;
Tran, Andy D;
Chung, Monika;
Chung, Natalie;
Gril, Brunilde;
Robinson, Christina;
Difilippantonio, Simone;
Wei, Debbie;
Kruhlak, Michael J;
Peer, Cody J;
Figg, W Douglas;
Khan, Imran;
Steeg, Patricia S

Publication type:

Article

HER2 antibody-drug conjugate controls growth of breast cancer brain metastases in hematogenous xenograft models, with heterogeneous blood–tumor barrier penetration unlinked to a passive marker.

Published in:

Neuro-Oncology, 2020, v. 22, n. 11, p. 1625, doi. 10.1093/neuonc/noaa118

By:

Gril, Brunilde;
Wei, Debbie;
Zimmer, Alexandra S;
Robinson, Christina;
Khan, Imran;
Difilippantonio, Simone;
Overstreet, Michael G;
Steeg, Patricia S

Publication type:

Article

Capecitabine and lapatinib uptake in surgically resected brain metastases from metastatic breast cancer patients: a prospective study.

Published in:

Neuro-Oncology, 2015, v. 17, n. 2, p. 289, doi. 10.1093/neuonc/nou141

By:

Morikawa, Aki;
Peereboom, David M.;
Thorsheim, Helen R.;
Samala, Ramakrishna;
Balyan, Rajiv;
Murphy, Conleth G.;
Lockman, Paul R.;
Simmons, Ahkeem;
Weil, Robert J.;
Tabar, Viviane;
Steeg, Patricia S.;
Smith, Quentin R.;
Seidman, Andrew D.

Publication type:

Article