Works by Staub, Olivier

Results: 35

SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2025, v. 477, n. 7, p. 977, doi. 10.1007/s00424-025-03093-5

By:

Fels, Benedikt;
Fischer, Felix;
Herrnboeck, Lisbeth;
Beckers, David;
Niedzielski, Leon;
Roche, Paul;
Straeter, Alexandra;
Alesutan, Ioana;
Borutta, Johanna-Theres;
Jaisser, Frederic;
Staub, Olivier;
Voelkl, Jakob;
Kusche-Vihrog, Kristina

Publication type:

Article

Does the early aldosterone‐induced SGK1 play a role in early Kaliuresis?

Published in:

Physiological Reports, 2022, v. 10, n. 4, p. 1, doi. 10.14814/phy2.15188

By:

Al‐Qusairi, Lama;
Basquin, Denis;
Stifanelli, Matteo;
Welling, Paul A.;
Staub, Olivier

Publication type:

Article

Stimulation of ENaC activity by rosiglitazone is PPARγ-dependent and correlates with SGK1 expression increase.

Published in:

2010

By:

Renauld, Stephane;
Tremblay, Karine;
Ait-Benichou, Siham;
Simoneau-Roy, Maxime;
Garneau, Hugo;
Staub, Olivier;
Chraïbi, Ahmed;
Chraïbi, Ahmed

Publication type:

journal article

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 2, p. 343, doi. 10.1007/s00424-013-1321-1

By:

Glaudemans, Bob;
Terryn, Sara;
Gölz, Nadine;
Brunati, Martina;
Cattaneo, Angela;
Bachi, Angela;
Al-Qusairi, Lama;
Ziegler, Urs;
Staub, Olivier;
Rampoldi, Luca;
Devuyst, Olivier

Publication type:

Article

Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.

Published in:

Pflügers Archiv: European Journal of Physiology, 2011, v. 462, n. 2, p. 267, doi. 10.1007/s00424-011-0971-0

By:

Wilkinson, William;
Benjamin, Audra;
Proost, Ian;
Orogo-Wenn, Maria;
Yamazaki, Yasuo;
Staub, Olivier;
Morita, Takashi;
Adriaensen, Dirk;
Riccardi, Daniela;
Walters, Dafydd;
Kemp, Paul

Publication type:

Article

Role of the ubiquitin system in regulating ion transport.

Published in:

Pflügers Archiv: European Journal of Physiology, 2011, v. 461, n. 1, p. 1, doi. 10.1007/s00424-010-0893-2

By:

Rotin, Daniela;
Staub, Olivier

Publication type:

Article

The role of Nedd4/Nedd4-like dependant ubiquitylation in epithelial transport processes.

Published in:

Pflügers Archiv: European Journal of Physiology, 2003, v. 446, n. 3, p. 334, doi. 10.1007/s00424-003-1027-x

By:

Flores, Sandra Y.;
Debonneville, Christophe;
Staub, Olivier

Publication type:

Article

Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na+/Cl– Cotransporter NCC and Transiently Affects Sodium Handling.

Published in:

Frontiers in Physiology, 2019, p. N.PAG, doi. 10.3389/fphys.2019.00989

By:

Canonica, Jérémie;
Frateschi, Simona;
Boscardin, Emilie;
Ebering, Anna;
Sergi, Chloé;
Jäger, Yannick;
Peyrollaz, Thibaud;
Mérillat, Anne-Marie;
Maillard, Marc;
Klusonova, Petra;
Odermatt, Alex;
Koesters, Robert;
Debonneville, Anne;
Staub, Olivier;
Verouti, Sophia N.;
Hummler, Edith

Publication type:

Article

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

Published in:

Cardiovascular Research, 2007, v. 74, n. 1, p. 64, doi. 10.1016/j.cardiores.2007.01.008

By:

Jespersen, Thomas;
Membrez, Mathieu;
Nicolas, Céline S.;
Pitard, Bruno;
Staub, Olivier;
Olesen, Søren-Peter;
Baró, Isabelle;
Abriel, Hugues

Publication type:

Article

Renal‐Tubular SGK1 is Involved in Blood Pressure Circadian Rhythm.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4953

By:

Al‐Qusairi, Lama;
Debonneville, Anne;
Stifanelli, Matteo;
Basquin, Denis;
Staub, Olivier

Publication type:

Article

The role of mineralocorticoid receptor in the potassium switch: effect on NCC regulation+.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R4463

By:

Li, Na;
Wang, Dongmei;
Reina, Patricia;
van Bemmelen, Miguel;
Belaid, Houwayda;
Maillard, Marc;
McCormick, James;
Ellison, David;
Staub, Olivier

Publication type:

Article

The E3 ubiquitin‐protein ligase Nedd4‐2 regulates the sodium chloride cotransporter (NCC) but is not required for a potassium‐induced reduction of NCC expression.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0R831

By:

Rosenbaek, Lena;
Petrillo, Federica;
Van Bemmelen, Miguel;
Staub, Olivier;
Murali, Sathish;
Fenton, Robert

Publication type:

Article

A‐Kinase anchoring protein 2 (AKAP2) and Pendrin; cross‐talk between cell signaling and renal physiology.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2873

By:

Belaid, Houwayda;
Wang, Dongmei;
Mendes Carraco, Ana;
Li, Na;
Van Bemmelen, Miguel;
Diviani, Dario;
Staub, Olivier

Publication type:

Article

Role of the renal mineralocorticoid receptor for potassium homeostasis.

Published in:

FASEB Journal, 2013, v. 27, p. 1210.6, doi. 10.1096/fasebj.27.1_supplement.1210.6

By:

Roesinger, Marian;
Loffing‐Cueni, Dominique;
Ronzaud, Caroline;
Canonica, Jérémie;
Debonneville, Anne;
Hummler, Edith;
Staub, Olivier;
Loffing, Johannes

Publication type:

Article

Usp2–45 represses aldosterone response by decreasing mineralocorticoid receptor availability.

Published in:

FASEB Journal, 2013, v. 27, p. 1115.23, doi. 10.1096/fasebj.27.1_supplement.1115.23

By:

Staub, Olivier;
Debonneville, Anne;
Pouly, Daniel;
Faresse, Nourdine

Publication type:

Article

Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation.

Published in:

FASEB Journal, 2012, v. 26, n. 10, p. 4373, doi. 10.1096/fj.12-209924

By:

Faresse, Nourdine;
Vitagliano, Jean-Jacques;
Staub, Olivier

Publication type:

Article

Nedd41 null mice are defective in down-regulating ENaC and have salt- sensitive hypertension.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A881

By:

Peijun Shi;
Xiao Cao;
Sweezer, Eileen;
Kinney, Thomas;
Volk, Kenneth;
Nair, Ramesh;
Williamson, Roger;
Staub, Olivier;
Stokes, John;
Baoli Yang

Publication type:

Article

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 657, doi. 10.1172/JCI61110

By:

Ronzaud, Caroline;
Loffing-Cueni, Dominique;
Hausel, Pierrette;
Debonneville, Anne;
Malsure, Sumedha Ram;
Fowler-Jaeger, Nicole;
Boase, Natasha A.;
Perrier, Romain;
Maillard, Marc;
Baoli Yang;
Stokes, John B.;
Koesters, Robert;
Kumar, Sharad;
Hummler, Edith;
Loffing, Johannes;
Staub, Olivier

Publication type:

Article

AQP2 Abundance is Regulated by the E3-Ligase CHIP Via HSP70.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 44, n. 2, p. 515, doi. 10.1159/000485088

By:

Centrone, Mariangela;
Ranieri, Marianna;
Di Mise, Annarita Di;
Berlingerio, Sante Princiero;
Russo, Annamaria;
Deen, Peter M.T.;
Staub, Olivier;
Valenti, Giovanna;
Tamma, Grazia

Publication type:

Article

USP2-45 Represses Aldosterone Mediated Responses by Decreasing Mineralocorticoid Receptor Availability.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 31, n. 2/3, p. 462, doi. 10.1159/000343382

By:

Faresse, Nourdine;
Debonneville, anne;
Staub, Olivier

Publication type:

Article

SIRT7 modulates the stability and activity of the renal K‐Cl cotransporter KCC4 through deacetylation.

Published in:

EMBO Reports, 2021, v. 22, n. 5, p. 1, doi. 10.15252/embr.202050766

By:

Noriega, Lilia G;
Melo, Zesergio;
Rajaram, Renuga D;
Mercado, Adriana;
Tovar, Armando R;
Velazquez‐Villegas, Laura A;
Castañeda‐Bueno, María;
Reyes‐López, Yazmín;
Ryu, Dongryeol;
Rojas‐Vega, Lorena;
Magaña‐Avila, German;
López‐Barradas, Adriana M;
Sánchez‐Hernández, Mariana;
Debonneville, Anne;
Doucet, Alain;
Cheval, Lydie;
Torres, Nimbe;
Auwerx, Johan;
Staub, Olivier;
Gamba, Gerardo

Publication type:

Article

The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron.

Published in:

Physiological Reports, 2019, v. 7, n. 15, p. N.PAG, doi. 10.14814/phy2.14177

By:

Spirli, Alessia;
Cheval, Lydie;
Debonneville, Anne;
Penton, David;
Ronzaud, Caroline;
Maillard, Marc;
Doucet, Alain;
Loffing, Johannes;
Staub, Olivier

Publication type:

Article

Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na+ channel cell surface expression.

Published in:

EMBO Journal, 2001, v. 20, n. 24, p. 7052, doi. 10.1093/emboj/20.24.7052

By:

Debonneville, Christophe;
Flores, Sandra Y.;
Kamynina, Elena;
Plant, Pamela J.;
Tauxe, Caroline;
Thomas, Marc A.;
Münster, Carole;
Chraïbi, Ahmed;
Pratt, J.Howard;
Horisberger, Jean‐Daniel;
Pearce, David;
Loffing, Johannes;
Staub, Olivier

Publication type:

Article

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na+ channel cell surface expression.

Published in:

EMBO Journal, 2001, v. 20, n. 24, p. 7052, doi. 10.1093/emboj/20.24.7052

By:

Debonneville, Christophe;
Flores, Sandra Y.;
Kamynina, Elena;
Plant, Pamela J.;
Tauxe, Caroline;
Thomas, Marc A.;
Münster, Carole;
Chraïbi, Ahmed;
Pratt, J. Howard;
Horisberger, Jean-Daniel;
Pearce, David;
Loffing, Johannes;
Staub, Olivier

Publication type:

Article

Participation of the Ubiquitin-Conjugating Enzyme UBE2E3 in Nedd4-2-Dependent Regulation of the Epithelial Na+ Channel.

Published in:

Molecular & Cellular Biology, 2004, v. 24, n. 6, p. 2397, doi. 10.1128/MCB.24.6.2397-2409.2004

By:

Debonneville, Christophe;
Staub, Olivier

Publication type:

Article

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 9, p. 3433, doi. 10.1172/JCI75245

By:

Roy, Ankita;
Al-Qusairi, Lama;
Donnelly, Bridget F.;
Ronzaud, Caroline;
Marciszyn, Allison L.;
Gong, Fan;
Chang, Y. P. Christy;
Butterworth, Michael B.;
Pastor-Soler, Núria M.;
Hallows, Kenneth R.;
Staub, Olivier;
Subramanya, Arohan R.

Publication type:

Article

Genetic dissection of sodium and potassium transport along the aldosterone-sensitive distal nephron: Importance in the control of blood pressure and hypertension.

Published in:

FEBS Letters, 2013, v. 587, n. 13, p. 1929, doi. 10.1016/j.febslet.2013.05.013

By:

Rossier, Bernard C.;
Staub, Olivier;
Hummler, Edith

Publication type:

Article

Nedd4-2 and the regulation of epithelial sodium transport.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00212

By:

Rotin, Daniela;
Staub, Olivier

Publication type:

Article

Nedd4-2 and the regulation of epithelial sodium transport.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00212

By:

Rotin, Daniela;
Staub, Olivier

Publication type:

Article

USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0145155

By:

Pouly, Daniel;
Chenaux, Sébastien;
Martin, Virginie;
Babis, Maja;
Koch, Rafael;
Nagoshi, Emi;
Katanaev, Vladimir L.;
Gachon, Frédéric;
Staub, Olivier

Publication type:

Article

Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl−-dependent and independent mechanisms.

Published in:

Journal of Physiology, 2016, v. 594, n. 21, p. 6319, doi. 10.1113/JP272504

By:

Penton, David;
Czogalla, Jan;
Wengi, Agnieszka;
Himmerkus, Nina;
Loffing‐Cueni, Dominique;
Carrel, Monique;
Rajaram, Renuga Devi;
Staub, Olivier;
Bleich, Markus;
Schweda, Frank;
Loffing, Johannes

Publication type:

Article

The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.971251

By:

Rosenbaek, Lena L.;
Petrillo, Federica;
van Bemmelen, Miguel X.;
Staub, Olivier;
Murali, Sathish K.;
Fenton, Robert A.

Publication type:

Article

Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel.

Published in:

2001

By:

Kamynina, Elena;
Debonneville, Christophe;
Hirt, Robert P.;
Staub, Olivier;
Kamynina, E;
Debonneville, C;
Hirt, R P;
Staub, O

Publication type:

journal article

Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination.

Published in:

Kidney International, 2000, v. 57, n. 3, p. 809, doi. 10.1046/j.1523-1755.2000.00919.x

By:

Staub, Olivier;
Abriel, Hugues;
Plant, Pamela;
Ishikawa, Toru;
Kanelis, Voula;
Saleki, Reza;
Horisberger, Jean-Daniel;
Schild, Laurent;
Rotin, Daniela

Publication type:

Article

HECT E3s and human disease.

Published in:

BMC Biochemistry, 2007, v. 8, p. 1, doi. 10.1186/1471-2091-8-S1-S6

By:

Scheffner, Martin;
Staub, Olivier

Publication type:

Article

Works by Staub, Olivier

SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells.

Does the early aldosterone‐induced SGK1 play a role in early Kaliuresis?

Stimulation of ENaC activity by rosiglitazone is PPARγ-dependent and correlates with SGK1 expression increase.

A primary culture system of mouse thick ascending limb cells with preserved function and uromodulin processing.

Alveolar epithelial CNGA1 channels mediate cGMP-stimulated, amiloride-insensitive, lung liquid absorption.

Role of the ubiquitin system in regulating ion transport.

The role of Nedd4/Nedd4-like dependant ubiquitylation in epithelial transport processes.

Lack of Renal Tubular Glucocorticoid Receptor Decreases the Thiazide-Sensitive Na<sup>+</sup>/Cl<sup>–</sup> Cotransporter NCC and Transiently Affects Sodium Handling.

The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family

Renal‐Tubular SGK1 is Involved in Blood Pressure Circadian Rhythm.

The role of mineralocorticoid receptor in the potassium switch: effect on NCC regulation<sup>+</sup>.

The E3 ubiquitin‐protein ligase Nedd4‐2 regulates the sodium chloride cotransporter (NCC) but is not required for a potassium‐induced reduction of NCC expression.

A‐Kinase anchoring protein 2 (AKAP2) and Pendrin; cross‐talk between cell signaling and renal physiology.

Role of the renal mineralocorticoid receptor for potassium homeostasis.

Usp2–45 represses aldosterone response by decreasing mineralocorticoid receptor availability.

Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation.

Nedd41 null mice are defective in down-regulating ENaC and have salt- sensitive hypertension.

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.

AQP2 Abundance is Regulated by the E3-Ligase CHIP Via HSP70.

USP2-45 Represses Aldosterone Mediated Responses by Decreasing Mineralocorticoid Receptor Availability.

SIRT7 modulates the stability and activity of the renal K‐Cl cotransporter KCC4 through deacetylation.

The serine‐threonine kinase PIM3 is an aldosterone‐regulated protein in the distal nephron.

Phosphorylation of Nedd4‐2 by Sgk1 regulates epithelial Na<sup>+</sup> channel cell surface expression.

Phosphorylation of Nedd4-2 by Sgk1 regulates epithelial Na<sup>+</sup> channel cell surface expression.

Participation of the Ubiquitin-Conjugating Enzyme UBE2E3 in Nedd4-2-Dependent Regulation of the Epithelial Na<sup>+</sup> Channel.

Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.

Genetic dissection of sodium and potassium transport along the aldosterone-sensitive distal nephron: Importance in the control of blood pressure and hypertension.

Nedd4-2 and the regulation of epithelial sodium transport.

Nedd4-2 and the regulation of epithelial sodium transport.

USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level.

Extracellular K<sup>+</sup> rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl<sup>−</sup>-dependent and independent mechanisms.

The E3 ubiquitin-protein ligase Nedd4-2 regulates the sodium chloride cotransporter NCC but is not required for a potassium-induced reduction of NCC expression.

Liddle's syndrome: a novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel.

Regulation of the epithelial Na<sup>+</sup> channel by Nedd4 and ubiquitination.

HECT E3s and human disease.