Works by Starkov, Anatoly A.

Results: 52

Guest Editorial.

Published in:

2019

By:

Chinopoulos, Christos;
Starkov, Anatoly

Publication type:

Editorial

HIF1a stabilization in hypoxia is not oxidant-initiated.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.72873

By:

Kumar, Amit;
Vaish, Manisha;
Karuppagounder, Saravanan S.;
Gazaryan, Irina;
Cave, John W.;
Starkov, Anatoly A.;
Anderson, Elizabeth T.;
Sheng Zhang;
Pinto, John T.;
Rountree, Austin M.;
Wang Wang;
Sweet, Ian R.;
Ratan, Rajiv R.

Publication type:

Article

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

Published in:

EMBO Molecular Medicine, 2010, v. 2, n. 9, p. 349, doi. 10.1002/emmm.201000084

By:

McConoughey, Stephen J.;
Basso, Manuela;
Niatsetskaya, Zoya V.;
Sleiman, Sama F.;
Smirnova, Natalia A.;
Langley, Brett C.;
Mahishi, Lata;
Cooper, Arthur J. L.;
Antonyak, Marc A.;
Cerione, Rick A.;
Li, Bo;
Starkov, Anatoly;
Chaturvedi, Rajnish Kumar;
Beal, M. Flint;
Coppola, Giovanni;
Geschwind, Daniel H.;
Ryu, Hoon;
Xia, Li;
Iismaa, Siiri E.;
Pallos, Judit

Publication type:

Article

Unique features of flight muscles mitochondria of honey bees (Apis mellifera L.).

Published in:

Archives of Insect Biochemistry & Physiology, 2019, v. 102, n. 1, p. N.PAG, doi. 10.1002/arch.21595

By:

Syromyatnikov, Mikhail Y.;
Gureev, Artem P.;
Vitkalova, Inna Y.;
Starkov, Anatoly A.;
Popov, Vasily N.

Publication type:

Article

Mitochondrial α-Ketoglutarate Dehydrogenase Complex Generates Reactive Oxygen Species.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7779, doi. 10.1523/JNEUROSCI.1899-04.2004

By:

Starkov, Anatoly A.;
Fiskum, Gary;
Chinopoulos, Christos;
Lorenzo, Beverly J.;
Browne, Susan E.;
Patel, Mulchand S.;
Beal, M. Flint

Publication type:

Article

Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice.

Published in:

FASEB Journal, 2011, v. 25, n. 11, p. 4063, doi. 10.1096/fj.11-186650

By:

Dumont, Magali;
Stack, Cliona;
Elipenahli, Ceyhan;
Jainuddin, Shari;
Gerges, Meri;
Starkova, Natalia N.;
Yang, Lichuan;
Starkov, Anatoly A.;
Beal, Flint

Publication type:

Article

Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria.

Published in:

FASEB Journal, 2010, v. 24, n. 12, p. 5033, doi. 10.1096/fj.10.166934

By:

Acin-Perez, Rebeca;
Hoyos, Beatrice;
Gong, Jianli;
Vinogradov, Valerie;
Fischman, Donald A.;
Leitges, Michael;
Borhan, Babak;
Starkov, Anatoly;
Manfredi, Giovanni;
Hammerling, Ulrich

Publication type:

Article

Regulation of intermediary metabolism by the PKCδ signalosome in mitochondria.

Published in:

FASEB Journal, 2010, v. 24, n. 12, p. 5033, doi. 10.1096/fj.10.166934

By:

Acin-Perez, Rebeca;
Hoyos, Beatrice;
Gong, Jianli;
Vinogradov, Valerie;
Fischman, Donald A.;
Leitges, Michael;
Borhan, Babak;
Starkov, Anatoly;
Manfredi, Giovanni;
Hammerling, Ulrich

Publication type:

Article

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.

Published in:

Human Molecular Genetics, 2018, v. 27, n. 16, p. 2874, doi. 10.1093/hmg/ddy201

By:

Tapias, Victor;
Jainuddin, Shari;
Ahuja, Manuj;
Stack, Cliona;
Elipenahli, Ceyhan;
Vignisse, Julie;
Gerges, Meri;
Starkova, Natalia;
Xu, Hui;
Starkov, Anatoly A

Publication type:

Article

Divalent cation chelators citrate and EDTA unmask an intrinsic uncoupling pathway in isolated mitochondria.

Published in:

Journal of Bioenergetics & Biomembranes, 2017, v. 49, n. 1, p. 3, doi. 10.1007/s10863-016-9656-x

By:

Starkov, Anatoly;
Chinopoulos, Christos;
Starkova, Natalia;
Konrad, Csaba;
Kiss, Gergely;
Stepanova, Anna;
Popov, Vasily

Publication type:

Article

Scavenging of HO by mouse brain mitochondria.

Published in:

Journal of Bioenergetics & Biomembranes, 2014, v. 46, n. 6, p. 471, doi. 10.1007/s10863-014-9581-9

By:

Starkov, Anatoly;
Starkova, Natalia;
Andreyev, Alexander;
Zhang, Steven;
Korneeva, Maria;
Syromyatnikov, Mikhail;
Popov, Vasily

Publication type:

Article

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.

Published in:

Journal of Neuroscience, 2016, v. 36, n. 23, p. 6332, doi. 10.1523/JNEUROSCI.0426-16.2016

By:

Ahuja, Manuj;
Kaidery, Navneet Ammal;
Lichuan Yang;
Calingasan, Noel;
Smirnova, Natalya;
Gaisin, Arsen;
Gaisina, Irina N.;
Gazaryan, Irina;
Hushpulian, Dmitry M.;
Kaddour-Djebbar, Ismail;
Bollag, Wendy B.;
Morgan, John C.;
Ratan, Rajiv R.;
Starkov, Anatoly A.;
Beal, M. Flint;
Thomas, Bobby

Publication type:

Article

An Isolation Method for Assessment of Brain Mitochondria Function in Neonatal Mice with Hypoxic-Ischemic Brain Injury.

Published in:

Developmental Neuroscience, 2008, v. 30, n. 5, p. 319, doi. 10.1159/000121416

By:

Caspersen, Casper S.;
Sosunov, Alexander;
Utkina-Sosunova, Irina;
Ratner, Veniamin I.;
Starkov, Anatoly A.;
Ten, Vadim S.

Publication type:

Article

Mild metabolic perturbations alter succinylation of mitochondrial proteins.

Published in:

Journal of Neuroscience Research, 2017, v. 95, n. 11, p. 2244, doi. 10.1002/jnr.24103

By:

Chen, Huanlian;
Xu, Hui;
Potash, Samuel;
Starkov, Anatoly;
Belousov, Vsevolod V.;
Bilan, Dmitry S.;
Denton, Travis T.;
Gibson, Gary E.

Publication type:

Article

Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 8, p. 2432, doi. 10.1093/brain/awt143

By:

Morató, Laia;
Galino, Jorge;
Ruiz, Montserrat;
Calingasan, Noel Ylagan;
Starkov, Anatoly A.;
Dumont, Magali;
Naudí, Alba;
Martínez, Juan José;
Aubourg, Patrick;
Portero-Otín, Manuel;
Pamplona, Reinald;
Galea, Elena;
Beal, M. Flint;
Ferrer, Isidre;
Fourcade, Stéphane;
Pujol, Aurora

Publication type:

Article

The mitochondrial calcium regulator cyclophilin D is an essential component of oestrogen-mediated neuroprotection in amyotrophic lateral sclerosis.

Published in:

Brain: A Journal of Neurology, 2012, v. 135, n. 9, p. 2865, doi. 10.1093/brain/aws208

By:

Kim, Hyun Jeong;
Magranè, Jordi;
Starkov, Anatoly A.;
Manfredi, Giovanni

Publication type:

Article

Portal to Alzheimer's disease.

Published in:

Nature Medicine, 2008, v. 14, n. 10, p. 1020, doi. 10.1038/nm1008-1020

By:

Starkov, Anatoly A;
Beal, Flint M

Publication type:

Article

Hypoxic Stress Exacerbates HyperoxiaInduced Lung Injury in a Neonatal Mouse Model of Bronchopulmonary Dysplasia.

Published in:

Neonatology (16617800), 2008, v. 95, n. 4, p. 299, doi. 10.1159/000178798

By:

Ratner, Veniamin;
Slinko, Siarhei;
Utkina-Sosunova, Irina;
Starkov, Anatoly;
Polin, Richard A.;
Ten, Vadim S.

Publication type:

Article

Truncated Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α Splice Variant Is Severely Altered in Huntington’s Disease.

Published in:

Neurodegenerative Diseases, 2011, v. 8, n. 6, p. 496, doi. 10.1159/000327910

By:

Johri, Ashu;
Starkov, Anatoly A.;
Chandra, Abhishek;
Hennessey, Thomas;
Sharma, Abhijeet;
Orobello, Sara;
Squitieri, Ferdinando;
Lichuan Yang;
Flint Beal, M.

Publication type:

Article

The mitochondrial respiratory chain is a modulator of apoptosis.

Published in:

Journal of Cell Biology, 2007, v. 179, n. 6, p. 1163, doi. 10.1083/jcb.200704059

By:

Kwong, Jennifer Q.;
Henning, Matthew S.;
Starkov, Anatoly A.;
Manfredi, Giovanni

Publication type:

Article

Mitochondrial calcium buffering depends upon temperature and is associated with hypothermic neuroprotection against hypoxia-ischemia injury.

Published in:

PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0273677

By:

Sosunov, Sergey;
Bhutada, Arnav;
Niatsetskaya, Zoya;
Starkov, Anatoly;
Ten, Vadim

Publication type:

Article

The Role of Mitochondria in Reactive Oxygen Species Metabolism and Signaling.

Published in:

Annals of the New York Academy of Sciences, 2008, v. 1147, p. 37, doi. 10.1196/annals.1427.015

By:

Starkov, Anatoly A.

Publication type:

Article

Mitochondrial Mechanisms of Neural Cell Death and Neuroprotective Interventions in Parkinson's Disease.

Published in:

Annals of the New York Academy of Sciences, 2003, v. 991, n. 1, p. 111, doi. 10.1111/j.1749-6632.2003.tb07469.x

By:

FISKUM, GARY;
STARKOV, ANATOLY;
POLSTER, BRIAN M.;
CHINOPOULOS, CHRISTOS

Publication type:

Article

Calcium and Mitochondrial Reactive Oxygen Species Generation: How to Read the Facts.

Published in:

Journal of Alzheimer's Disease, 2010, v. 20, p. 413, doi. 10.3233/JAD-2010-100465

By:

Adam-Vizi, Vera;
Starkov, Anatoly A.

Publication type:

Article

Calcium and mitochondrial reactive oxygen species generation: how to read the facts.

Published in:

2010

By:

Adam-Vizi V;
Starkov AA;
Adam-Vizi, Vera;
Starkov, Anatoly A

Publication type:

journal article

Methylenedioxymethamphetamine inhibits mitochondrial complex I activity in mice: a possible mechanism underlying neurotoxicity.

Published in:

2010

By:

Puerta, Elena;
Hervias, Isabel;
Goñi-Allo, Beatriz;
Zhang, Steven F;
Jordán, Joaquín;
Starkov, Anatoly A;
Aguirre, Norberto;
Goñi-Allo, Beatriz;
Jordán, Joaquín

Publication type:

journal article

Methylene blue does not bypass Complex III antimycin block in mouse brain mitochondria.

Published in:

FEBS Letters, 2019, v. 593, n. 5, p. 499, doi. 10.1002/1873-3468.13332

By:

Gureev, Artem P.;
Shaforostova, Ekaterina A.;
Popov, Vasily N.;
Starkov, Anatoly A.

Publication type:

Article

Prohibitin is a positive modulator of mitochondrial function in PC12 cells under oxidative stress.

Published in:

Journal of Neurochemistry, 2018, v. 146, n. 3, p. 235, doi. 10.1111/jnc.14472

By:

Anderson, Corey J.;
Kahl, Anja;
Qian, Liping;
Stepanova, Anna;
Starkov, Anatoly;
Manfredi, Giovanni;
Iadecola, Costantino;
Zhou, Ping

Publication type:

Article

Autophagy Induction by Bexarotene Promotes Mitophagy in Presenilin 1 Familial Alzheimer's Disease iPSC-Derived Neural Stem Cells.

Published in:

Molecular Neurobiology, 2019, v. 56, n. 12, p. 8220, doi. 10.1007/s12035-019-01665-y

By:

Martín-Maestro, Patricia;
Sproul, Andrew;
Martinez, Hector;
Paquet, Dominik;
Gerges, Meri;
Noggle, Scott;
Starkov, Anatoly A.

Publication type:

Article

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells.

Published in:

Scientific Reports, 2016, p. 26700, doi. 10.1038/srep26700

By:

Doczi, Judit;
Torocsik, Beata;
Echaniz-Laguna, Andoni;
Mousson de Camaret, Bénédicte;
Starkov, Anatoly;
Starkova, Natalia;
Gál, Aniko;
Molnár, Mária J;
Kawamata, Hibiki;
Manfredi, Giovanni;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 14, p. 3716, doi. 10.1093/hmg/ddu080

By:

Stack, Cliona;
Jainuddin, Shari;
Elipenahli, Ceyhan;
Gerges, Meri;
Starkova, Natalia;
Starkov, Anatoly A.;
Jové, Mariona;
Portero-Otin, Manuel;
Launay, Nathalie;
Pujol, Aurora;
Kaidery, Navneet Ammal;
Thomas, Bobby;
Tampellini, Davide;
Beal, M. Flint;
Dumont, Magali

Publication type:

Article

Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 23, p. 5091, doi. 10.1093/hmg/dds355

By:

Dumont, Magali;
Stack, Cliona;
Elipenahli, Ceyhan;
Jainuddin, Shari;
Gerges, Meri;
Starkova, Natalia;
Calingasan, Noel Y.;
Yang, Lichuan;
Tampellini, Davide;
Starkov, Anatoly A.;
Chan, Robin B.;
Di Paolo, Gilbert;
Pujol, Aurora;
Beal, M. Flint

Publication type:

Article

Impaired PGC-1α function in muscle in Huntington's disease.

Published in:

Human Molecular Genetics, 2009, v. 18, n. 16, p. 3048, doi. 10.1093/hmg/ddp243

By:

Chaturvedi, Rajnish K.;
Adhihetty, Peter;
Shukla, Shubha;
Hennessy, Thomas;
Calingasan, Noel;
Yang, Lichuan;
Starkov, Anatoly;
Kiaei, Mahmoud;
Cannella, Milena;
Sassone, Jenny;
Ciammola, Andrea;
Squitieri, Fernando;
Beal, M. Flint

Publication type:

Article

Hypoxic-Ischemic Injury in the Developing Brain: The Role of Reactive Oxygen Species Originating in Mitochondria.

Published in:

Neurology Research International, 2012, p. 1, doi. 10.1155/2012/542976

By:

Ten, VadimS.;
Starkov, Anatoly

Publication type:

Article

The Oxygen Free Radicals Originating from Mitochondrial Complex I Contribute to Oxidative Brain Injury Following Hypoxia-Ischemia in Neonatal Mice.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 9, p. 3235, doi. 10.1523/JNEUROSCI.6303-11.2012

By:

Niatsetskaya, Zoya V.;
Sosunov, Sergei A.;
Matsiukevich, Dzmitry;
Utkina-Sosunova, Irina V.;
Ratner, Veniamin I.;
Starkov, Anatoly A.;
Ten, Vadim S.

Publication type:

Article

In Vivo Pathogenic Role of Mutant SOD1 Localized in the Mitochondrial Intermembrane Space.

Published in:

Journal of Neuroscience, 2011, v. 31, n. 44, p. 15826, doi. 10.1523/JNEUROSCI.1965-11.2011

By:

Igoudjil, Anissa;
Magrané, Jordi;
Fischer, Lindsey R.;
Kim, Hyun Jeong;
Hervias, Isabel;
Dumont, Magali;
Cortez, Czrina;
Glass, Jonathan D.;
Starkov, Anatoly A.;
Manfredi, Giovanni

Publication type:

Article

Complement Component C1q Mediates Mitochondria-Driven Oxidative Stress in Neonatal Hypoxic—Ischemic Brain Injury.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 6, p. 2077, doi. 10.1523/JNEUROSCI.5249-09.2010

By:

Ten, Vadim S.;
Jun Yao;
Ratner, Veniamin;
Sosunov, Sergey;
Fraser, Deborah A.;
Botto, Marina;
Sivasankar, Baalasubramanian;
Morgan, B. Paul;
Silverstein, Samuel;
Stark, Raymond;
Polin, Richard;
Vannucci, Susan J.;
Pinsky, David;
Starkov, Anatoly A.

Publication type:

Article

Modulation of F.

Published in:

FEBS Journal, 2011, v. 278, n. 7, p. 1112, doi. 10.1111/j.1742-4658.2011.08026.x

By:

Chinopoulos, Christos;
Konràd, Csaba;
Kiss, Gergely;
Metelkin, Eugeniy;
Töröcsik, Beata;
Zhang, Steven F.;
Starkov, Anatoly A.

Publication type:

Article

The molecular identity of the mitochondrial Ca2+ sequestration system.

Published in:

FEBS Journal, 2010, v. 277, n. 18, p. 3652, doi. 10.1111/j.1742-4658.2010.07756.x

By:

Starkov, Anatoly A.

Publication type:

Article

Mitochondrial Dysfunction and Permeability Transition in Neonatal Brain and Lung Injuries.

Published in:

Cells (2073-4409), 2021, v. 10, n. 3, p. 569, doi. 10.3390/cells10030569

By:

S. Ten, Vadim;
Stepanova, Anna A.;
Ratner, Veniamin;
Neginskaya, Maria;
Niatsetskaya, Zoya;
Sosunov, Sergey;
Starkov, Anatoly;
Bernardi, Paolo

Publication type:

Article

Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0180-1

By:

Hibiki Kawamata;
Peixoto, Pablo;
Konrad, Csaba;
Palomo, Gloria;
Bredvik, Kirsten;
Gerges, Meri;
Valsecchi, Federica;
Petrucelli, Leonard;
Ravits, John M.;
Starkov, Anatoly;
Manfredi, Giovanni

Publication type:

Article

Mitochondrial Dysfunction Contributes to Alveolar Developmental Arrest in Hyperoxia-Exposed Mice.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2009, v. 40, n. 5, p. 511, doi. 10.1165/rcmb.2008-0341RC

By:

Ratner, Veniamin;
Starkov, Anatoly;
Matsiukevich, Dzmitry;
Polin, Richard A.;
Ten, Vadim S.

Publication type:

Article

Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2017, v. 37, n. 12, p. 3649, doi. 10.1177/0271678X17730242

By:

Stepanova, Anna;
Kahl, Anja;
Konrad, Csaba;
Ten, Vadim;
Starkov, Anatoly S.;
Galkin, Alexander

Publication type:

Article

Mild hypoxemia during initial reperfusion alleviates the severity of secondary energy failure and protects brain in neonatal mice with hypoxic-ischemic injury.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 2, p. 232, doi. 10.1038/jcbfm.2011.164

By:

Niatsetskaya, Zoya V;
Charlagorla, Pradeep;
Matsukevich, Dzmitry A;
Sosunov, Sergey A;
Mayurasakorn, Korapat;
Ratner, Veniamin I;
Polin, Richard A;
Starkov, Anatoly A;
Ten, Vadim S

Publication type:

Article

p62-Nrf2-p62 Mitophagy Regulatory Loop as a Target for Preventive Therapy of Neurodegenerative Diseases.

Published in:

Brain Sciences (2076-3425), 2020, v. 10, n. 11, p. 847, doi. 10.3390/brainsci10110847

By:

Gureev, Artem P.;
Sadovnikova, Irina S.;
Starkova, Natalia N.;
Starkov, Anatoly A.;
Popov, Vasily N.

Publication type:

Article

β-Guanidinopropionic Acid Stimulates Brain Mitochondria Biogenesis and Alters Cognitive Behavior in Nondiseased Mid-Age Mice.

Published in:

Journal of Experimental Neuroscience, 2018, v. 12, p. 1, doi. 10.1177/1179069518766524

By:

Gureev, Artem P.;
Shaforostova, Ekaterina A.;
Starkov, Anatoly A.;
Popov, Vasily N.

Publication type:

Article

PGC-lα overexpression exacerbates ß-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease.

Published in:

FASEB Journal, 2014, v. 28, n. 4, p. 1745, doi. 10.1096/fj.13-236331

By:

Dumont, Magali;
Stack, Cliona;
Elipenahli, Ceyhan;
Jainuddin, Shari;
Launay, Nathalie;
Gerges, Meri;
Starkova, Natalia;
Starkov, Anatoly A.;
Calingasan, Noel Y.;
Tampellini, Davide;
Pujo, Aurora;
Beai, M. Flint

Publication type:

Article

Mitochondrial diaphorases as NAD+ donors to segments of the citric acid cycle that support substrate-level phosphorylation yielding ATP during respiratory inhibition.

Published in:

FASEB Journal, 2014, v. 28, n. 4, p. 1682, doi. 10.1096/fj.13-243030

By:

Kiss, Gergely;
Konrad, Csaba;
Pour-Ghaz, Issa;
Mansour, Josef J.;
Németh, Beata;
Starkov, Anatoly A.;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation.

Published in:

FASEB Journal, 2013, v. 27, n. 6, p. 2392, doi. 10.1096/fj.12-220202

By:

Kiss, Gergely;
Konrad, Csaba;
Doczi, Judit;
Starkov, Anatoly A.;
Kawamata, Hibiki;
Manfredi, Giovanni;
Zhang, Steven F.;
Gibson, Gary E.;
Beal, M. Flint;
Adam-Vizi, Vera;
Chinopoulos, Christos

Publication type:

Article

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice.

Published in:

Journal of Neurochemistry, 2006, v. 96, n. 5, p. 1349, doi. 10.1111/j.1471-4159.2006.03619.x

By:

Damiano, Maria;
Starkov, Anatoly A.;
Petri, Susanne;
Kipiani, Kathuna;
Kiaei, Mahmoud;
Mattiazzi, Marina;
Flint Beal, M.;
Manfredi, Giovanni

Publication type:

Article