Models of beta-amyloid induced Tau-pathology: the long and "folded" road to understand the mechanism.
- Published in:
- Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 155, doi. 10.1186/1750-1326-9-51
- By:
- Publication type:
- Article
Works by Stancu, Ilie Cosmin
Results: 13
1
2
Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease.
- Published in:
- 2016
- By:
- Publication type:
- journal article
3
The NLRP3 inflammasome modulates tau pathology and neurodegeneration in a tauopathy model.
- Published in:
- Glia (0894-1491), 2022, v. 70, n. 6, p. 1117, doi. 10.1002/glia.24160
- By:
- Publication type:
- Article
4
Blood-based Aβ42 increases in the earliest pre-pathological stage before decreasing with progressive amyloid pathology in preclinical models and human subjects: opening new avenues for prevention.
- Published in:
- Acta Neuropathologica, 2022, v. 144, n. 3, p. 489, doi. 10.1007/s00401-022-02458-9
- By:
- Publication type:
- Article
5
Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo.
- Published in:
- Acta Neuropathologica, 2019, v. 137, n. 4, p. 599, doi. 10.1007/s00401-018-01957-y
- By:
- Publication type:
- Article
6
Tau interactome mapping based identification of Otub1 as Tau deubiquitinase involved in accumulation of pathological Tau forms in vitro and in vivo.
- Published in:
- Acta Neuropathologica, 2017, v. 133, n. 5, p. 731, doi. 10.1007/s00401-016-1663-9
- By:
- Publication type:
- Article
7
Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo.
- Published in:
- Acta Neuropathologica, 2016, v. 131, n. 4, p. 549, doi. 10.1007/s00401-015-1525-x
- By:
- Publication type:
- Article
8
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice.
- Published in:
- Acta Neuropathologica, 2015, v. 129, n. 6, p. 875, doi. 10.1007/s00401-015-1413-4
- By:
- Publication type:
- Article
9
CSF1R inhibition rescues tau pathology and neurodegeneration in an A/T/N model with combined AD pathologies, while preserving plaque associated microglia.
- Published in:
- Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01204-8
- By:
- Publication type:
- Article
10
Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease.
- Published in:
- FASEB Journal, 2014, v. 28, n. 6, p. 2620, doi. 10.1096/fj.13-246702
- By:
- Publication type:
- Article
11
IDENTIFICATION OF NOVEL TARGETS FOR INHIBITING PRION-LIKE SEEDING AND PROPAGATION OF TAU PATHOLOGY IN VITRO AND IN VIVO.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1270, doi. 10.1016/j.jalz.2017.06.1901
- By:
- Publication type:
- Article
12
MOLECULAR MECHANISMS OF ABETA-INDUCED TAU-PATHOLOGY: ANALYSIS OF CROSS-SEEDING OF ABETA AND TAU AND ITS ROLE IN PRION-LIKE PROPAGATION OF TAU-PATHOLOGY IN VITRO AND IN VIVO.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P385, doi. 10.1016/j.jalz.2016.06.722
- By:
- Publication type:
- Article
13
IDENTIFICATION AND VALIDATION OF TAU-MODIFIERS, IDENTIFIED BY UNBIASED GENOME WIDE APPROACHES, USING AAV-BASED APPROACHES IN TAU TRANSGENIC MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P845, doi. 10.1016/j.jalz.2016.06.1730
- By:
- Publication type:
- Article