Works by Staels B

Results: 40

Association between liver X receptor alpha gene polymorphisms and risk of metabolic syndrome in French populations.

Published in:

2008

By:

Legry V;
Cottel D;
Ferrières J;
Chinetti G;
Deroide T;
Staels B;
Amouyel P;
Meirhaeghe A;
Legry, V;
Cottel, D;
Ferrières, J;
Chinetti, G;
Deroide, T;
Staels, B;
Amouyel, P;
Meirhaeghe, A

Publication type:

journal article

Bile acid sequestrants and the treatment of type 2 diabetes mellitus.

Published in:

2007

By:

Staels B;
Kuipers F

Publication type:

Journal Article

Peroxisome proliferator-activated receptors – from active regulators of macrophage biology to pharmacological targets in the treatment of cardiovascular disease.

Published in:

Journal of Internal Medicine, 2008, v. 263, n. 1, p. 28, doi. 10.1111/j.1365-2796.2007.01892.x

By:

Bouhlel, M. A.;
Staels, B.;
Chinetti-Gbaguidi, G.

Publication type:

Article

No short-term effect of oral isotretinoin (13-cis retinoic acid) on lipoprotein(a) and HDL subclasses LP-A-I and LP-A-I:A-II in healthy volunteers.

Published in:

1999

By:

Neele, D. M.;
Buytenhek, R.;
Staels, B.;
Dallongeville, J.;
Wallnöfer, A. E.;
Kooistra, T.;
Princen, H. M. G.;
Wallnöfer, A E;
Princen, H M

Publication type:

clinical trial

Downregulation of the tumour suppressor p16 contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.

Published in:

Diabetologia, 2011, v. 54, n. 12, p. 3150, doi. 10.1007/s00125-011-2324-0

By:

Fuentes, L.;
Wouters, K.;
Hannou, S.;
Cudejko, C.;
Rigamonti, E.;
Mayi, T.;
Derudas, B.;
Pattou, F.;
Chinetti-Gbaguidi, G.;
Staels, B.;
Paumelle, R.

Publication type:

Article

The effect of sensitisation to insulin with pioglitazone on fasting and postprandial lipid metabolism, lipoprotein modification by lipases, and lipid transfer activities in type 2 diabetic patients.

Published in:

Diabetologia, 2006, v. 49, n. 3, p. 527, doi. 10.1007/s00125-005-0092-4

By:

Al Majali, K.;
Cooper, M. B.;
Staels, B.;
Luc, G.;
Taskinen, M.-R.;
Betteridge, D. J.

Publication type:

Article

Variation in the PPARα gene is associated with altered function in vitro and plasma lipid concentrations in Type II diabetic subjects.

Published in:

Diabetologia, 2000, v. 43, n. 5, p. 673, doi. 10.1007/s001250051357

By:

Flavell, D. M.;
Torra, I. Pineda;
Jamshidi, Y.;
Evans, D.;
Diamond, J. R.;
Elkeles, R. S.;
Bujac, S. R.;
Miller, G.;
Talmud, P. J.;
Staels, B.;
Humphries, S. E.

Publication type:

Article

PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.

Published in:

2001

By:

Guerre-Millo, Michèle;
Rouault, Christine;
Poulain, Philippe;
André, Jocelyne;
Poitout, Vincent;
Peters, Jeffrey M.;
Gonzalez, Frank J.;
Fruchart, Jean-Charles;
Reach, Gérard;
Staels, Bart;
Guerre-Millo, M;
Rouault, C;
Poulain, P;
André, J;
Poitout, V;
Peters, J M;
Gonzalez, F J;
Fruchart, J C;
Reach, G;
Staels, B

Publication type:

journal article

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients.

Published in:

1997

By:

Auboeuf, Didier;
Rieusset, Jennifer;
Fajas, Lluis;
Vallier, Paulette;
Frering, Vincent;
Riou, Jean Paul;
Staels, Bart;
Auwerx, Johan;
Laville, Martine;
Vidal, Hubert;
Auboeuf, D;
Rieusset, J;
Fajas, L;
Vallier, P;
Frering, V;
Riou, J P;
Staels, B;
Auwerx, J;
Laville, M;
Vidal, H

Publication type:

journal article

Generation and characterization of a humanized PPARδ mouse model.

Published in:

2011

By:

Gross, B;
Hennuyer, N;
Bouchaert, E;
Rommens, C;
Grillot, D;
Mezdour, H;
Staels, B

Publication type:

journal article

Cell Culture Conditions Determine Apolipoprotein CIII Secretion and Regulation by Fibrates in Human Hepatoma HepG2 Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 1999, v. 9, n. 3, p. 139, doi. 10.1159/000016311

By:

Clavey, V.;
Copin, C.;
Mariotte, M.C.;
Baugé, E.;
Chinetti, G.;
Fruchart, J.;
Fruchart, J.C.;
Dallongeville, J.;
Staels, B.

Publication type:

Article

ATL>Peroxisome proliferator-activated receptor (PPAR) agonists decrease lipoprotein lipase secretion and glycated LDL uptake by human macrophages.

Published in:

FEBS Letters, 2002, v. 512, n. 1-3, p. 85, doi. 10.1016/S0014-5793(02)02223-8

By:

Gbaguidi, F.G.;
Chinetti, G.;
Milosavljevic, D.;
Teissier, E.;
Chapman, J.;
Olivecrona, G.;
Fruchart, J.C.;
Griglio, S.;
Fruchart-Najib, J.;
Staels, B.

Publication type:

Article

Topical ivermectin improves allergic skin inflammation.

Published in:

Allergy, 2017, v. 72, n. 8, p. 1212, doi. 10.1111/all.13118

By:

Ventre, E.;
Rozières, A.;
Lenief, V.;
Albert, F.;
Rossio, P.;
Laoubi, L.;
Dombrowicz, D.;
Staels, B.;
Ulmann, L.;
Julia, V.;
Vial, E.;
Jomard, A.;
Hacini‐Rachinel, F.;
Nicolas, J.‐F.;
Vocanson, M.

Publication type:

Article

Association of 1-deoxy-sphingolipids with steatosis but not steatohepatitis nor fibrosis in non-alcoholic fatty liver disease.

Published in:

Acta Diabetologica, 2021, v. 58, n. 3, p. 319, doi. 10.1007/s00592-020-01612-7

By:

Weyler, J.;
Verrijken, A.;
Hornemann, T.;
Vonghia, L.;
Dirinck, E.;
von Eckardstein, A.;
Vanwolleghem, T.;
Michielsen, P.;
Peiffer, F.;
Driessen, A.;
Hubens, G.;
Staels, B.;
Francque, S.;
Van Gaal, L.

Publication type:

Article

85 Transcriptional regulation of cardiac fatty acid metabolism: redundancy of the ligand-activated nuclear hormone receptors PPARa and PPARb/d

Published in:

2004

By:

Gilde, A.;
Van der Lee, K.;
Willemsen, P.;
Chinetti, G.;
Van der Leij, F.;
Van der Vusse, G.;
Staels, B.;
Van Bilsen, M.

Publication type:

Abstract

Profiling Serum Bile Acid Glucuronides in Humans: Gender Divergences, Genetic Determinants, and Response to Fenofibrate.

Published in:

Clinical Pharmacology & Therapeutics, 2013, v. 94, n. 4, p. 533, doi. 10.1038/clpt.2013.122

By:

Trottier, J;
Perreault, M;
Rudkowska, I;
Levy, C;
Dallaire‐Theroux, A;
Verreault, M;
Caron, P;
Staels, B;
Vohl, M‐C;
Straka, R J;
Barbier, O

Publication type:

Article

Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes.

Published in:

2015

By:

Dutia, R;
Embrey, M;
O'Brien, S;
Haeusler, R A;
Agénor, K K;
Homel, P;
McGinty, J;
Vincent, R P;
Alaghband-Zadeh, J;
Staels, B;
le Roux, C W;
Yu, J;
Laferrère, B;
O'Brien, C S

Publication type:

journal article

Temporal changes in bile acid levels and 12α-hydroxylation after Roux-en-Y gastric bypass surgery in type 2 diabetes.

Published in:

International Journal of Obesity, 2015, v. 39, n. 5, p. 806, doi. 10.1038/ijo.2015.1

By:

Dutia, R;
Embrey, M;
O'Brien, S;
Haeusler, R A;
Agénor, K K;
Homel, P;
McGinty, J;
Vincent, R P;
Alaghband-Zadeh, J;
Staels, B;
le Roux, C W;
Yu, J;
Laferrère, B

Publication type:

Article

Association between liver X receptor α gene polymorphisms and risk of metabolic syndrome in French populations.

Published in:

International Journal of Obesity, 2008, v. 32, n. 3, p. 421, doi. 10.1038/sj.ijo.0803705

By:

Legry, V.;
Cottel, D.;
Ferrières, J.;
Chinetti, G.;
Deroide, T.;
Staels, B.;
Amouyel, P.;
Meirhaeghe, A.

Publication type:

Article

The coronary artery disease-associated gene C6ORF105 is expressed in human macrophages under the transcriptional control of PPARγ.

Published in:

FEBS Letters, 2015, v. 589, n. 4, p. 461, doi. 10.1016/j.febslet.2015.01.002

By:

Chinetti-Gbaguidi, G.;
Copin, C.;
Derudas, B.;
Vanhoutte, J.;
Zawadzki, C.;
Jude, B.;
Haulon, S.;
Pattou, F.;
Marx, N.;
Staels, B.

Publication type:

Article

A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.

Published in:

Obesity (19307381), 2013, v. 21, n. 10, p. 2138, doi. 10.1002/oby.20366

By:

Verrijken, A.;
Beckers, S.;
Francque, S.;
Hilden, H.;
Caron, S.;
Zegers, D.;
Ruppert, M.;
Hubens, G.;
Marck, E.;
Michielsen, P.;
Staels, B.;
Taskinen, M.‐R.;
Hul, W.;
Gaal, L.

Publication type:

Article

Therapeutical effects of PPAR agonists assessed by biomarker modulation.

Published in:

Biomarkers, 2005, v. 10, p. 30, doi. 10.1080/13547500500216702

By:

Chinetti-Gbaguidi, G.;
Fruchart, J.-C.;
Staels, B.

Publication type:

Article

Effects of the new dual PPAR α/δ agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism.

Published in:

2011

By:

Cariou B;
Zaïr Y;
Staels B;
Bruckert E;
Cariou, Bertrand;
Zaïr, Yassine;
Staels, Bart;
Bruckert, Eric

Publication type:

journal article

Bile acids and metabolic regulation: mechanisms and clinical responses to bile acid sequestration.

Published in:

2009

By:

Staels B;
Fonseca VA;
Staels, Bart;
Fonseca, Vivian A

Publication type:

journal article

Bile acid metabolism and the pathogenesis of type 2 diabetes.

Published in:

2011

By:

Prawitt J;
Caron S;
Staels B;
Prawitt, Janne;
Caron, Sandrine;
Staels, Bart

Publication type:

journal article

Peroxisome Proliferator-Activated Receptor γ Induces the Expression of Tissue Factor Pathway Inhibitor-1 (TFPI-1) in Human Macrophages.

Published in:

PPAR Research, 2016, p. 1, doi. 10.1155/2016/2756781

By:

Chinetti-Gbaguidi, G.;
Copin, C.;
Derudas, B.;
Marx, N.;
Eechkoute, J.;
Staels, B.

Publication type:

Article

Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.

Published in:

2011

By:

Favre D;
Le Gouill E;
Fahmi D;
Verdumo C;
Chinetti-Gbaguidi G;
Staels B;
Caiazzo R;
Pattou F;
Lê KA;
Tappy L;
Regazzi R;
Giusti V;
Vollenweider P;
Waeber G;
Abderrahmani A;
Favre, Dimitri;
Le Gouill, Eric;
Fahmi, Denis;
Verdumo, Chantal;
Chinetti-Gbaguidi, Giulia

Publication type:

journal article

The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta.

Published in:

2010

By:

Riahi Y;
Sin-Malia Y;
Cohen G;
Alpert E;
Gruzman A;
Eckel J;
Staels B;
Guichardant M;
Sasson S;
Riahi, Yael;
Sin-Malia, Yoav;
Cohen, Guy;
Alpert, Evgenia;
Gruzman, Arie;
Eckel, Juergen;
Staels, Bart;
Guichardant, Michel;
Sasson, Shlomo

Publication type:

journal article

Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.

Published in:

2008

By:

Clemenz M;
Frost N;
Schupp M;
Caron S;
Foryst-Ludwig A;
Böhm C;
Hartge M;
Gust R;
Staels B;
Unger T;
Kintscher U

Publication type:

Journal Article

PPARalpha agonists suppress osteopontin expression in macrophages and decrease plasma levels in patients with type 2 diabetes.

Published in:

2007

By:

Nakamachi T;
Nomiyama T;
Gizard F;
Heywood EB;
Jones KL;
Zhao Y;
Fuentes L;
Takebayashi K;
Aso Y;
Staels B;
Inukai T;
Bruemmer D

Publication type:

Journal Article

Transcription Factor TCF7L2 Genetic Study in the French Population: Expression in Human {beta}-Cells and Adipose Tissue and Strong Association With Type 2 Diabetes.

Published in:

2006

By:

Cauchi S;
Meyre D;
Dina C;
Choquet H;
Samson C;
Gallina S;
Balkau B;
Charpentier G;
Pattou F;
Stetsyuk V;
Scharfmann R;
Staels B;
Frühbeck G;
Froguel P

Publication type:

Journal Article

Peroxisome proliferator-activated receptor alpha improves pancreatic adaptation to insulin resistance in obese mice and reduces lipotoxicity in human islets.

Published in:

2006

By:

Lalloyer F;
Vandewalle B;
Percevault F;
Torpier G;
Kerr-Conte J;
Oosterveer M;
Paumelle R;
Fruchart J;
Kuipers F;
Pattou F;
Fiévet C;
Staels B

Publication type:

Journal Article

Therapeutic roles of peroxisome proliferator-activated receptor agonists.

Published in:

2005

By:

Staels B;
Fruchart J;
Staels, Bart;
Fruchart, Jean-Charles

Publication type:

journal article

The mitochondrion is the principal target for nutritional and pharmacological control of plasma triglyceride.

Published in:

Lipids, 1999, v. 34, p. S167, doi. 10.1007/BF02562277

By:

Madsen, L.;
Frøyland, L.;
Kryvi, H.;
Auwerx, J.;
Staels, B.;
Berge, R.

Publication type:

Article

Nuclear transcription factors: new opportunities for lipid lowering.

Published in:

2000

By:

Staels, B

Publication type:

journal article

Inflammation, dyslipidaemia, diabetes and PPars: pharmacological interest of dual PPARalpha and PPARgamma agonists.

Published in:

2004

By:

Gervois P;
Fruchart JC;
Staels B

Publication type:

Journal Article

Inflammation, dyslipidaemia, diabetes and PPARs: pharmacological interest of dual PPARα and PPARγ agonists.

Published in:

International Journal of Clinical Practice (Supplement), 2004, v. 58, p. 22, doi. 10.1111/j.1368-504X.2004.00376.x

By:

Gervois, P.;
Fruchart, J.-C.;
Staels, B.

Publication type:

Article

Skeletal muscle functions around the clock.

Published in:

Diabetes, Obesity & Metabolism, 2015, v. 17, p. 39, doi. 10.1111/dom.12517

By:

Mayeuf-Louchart, A.;
Staels, B.;
Duez, H.

Publication type:

Article

Efficacy and safety of initial combination treatment with sitagliptin and pioglitazone-a factorial study.

Published in:

Diabetes, Obesity & Metabolism, 2014, v. 16, n. 3, p. 223, doi. 10.1111/dom.12194

By:

Henry, R. R.;
Staels, B.;
Fonseca, V. A.;
Chou, M. Z.;
Teng, R.;
Golm, G. T.;
Langdon, R. B.;
Kaufman, K. D.;
Steinberg, H.;
Goldstein, B. J.

Publication type:

Article

The anti-obesity effect of rimonabant is associated with an improved serum lipid profile.

Published in:

Diabetes, Obesity & Metabolism, 2005, v. 7, n. 1, p. 65, doi. 10.1111/j.1463-1326.2004.00374.x

By:

Poirier, B.;
Bidouard, J.-P.;
Cadrouvele, C.;
Marniquet, X.;
Staels, B.;
O'Connor, S. E.;
Janiak, P.;
Herbert, J.-M.

Publication type:

Article