Works by Srivastava, Shashikant

Results: 59

Editorial: Pharmacology of infectious diseases: world tuberculosis day 2022.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1233347

By:

Srivastava, Shashikant;
Alffenaar, Johannes W.;
Wicha, Sebastian G.

Publication type:

Article

Minocycline Immunomodulates via Sonic Hedgehog Signaling and Apoptosis and Has Direct Potency Against Drug-Resistant Tuberculosis.

Published in:

2019

By:

Deshpande, Devyani;
Pasipanodya, Jotam G;
Srivastava, Shashikant;
Martin, Katherine R;
Athale, Shruti;
Zyl, Johanna van;
Antiabong, John;
Koeuth, Thearith;
Lee, Pooi S;
Dheda, Keertan;
Gumbo, Tawanda;
van Zyl, Johanna

Publication type:

journal article

Fatal Lure of Look-Back Studies in Explaining Pharmacological Events Such as Acquired Drug Resistance in Patients With Multidrug-Resistant Tuberculosis.

Published in:

2015

By:

Pasipanodya, Jotam;
Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

Journal Article

Fatal Lure of Look-Back Studies in Explaining Pharmacological Events Such as Acquired Drug Resistance in Patients With Multidrug- Resistant Tuberculosis.

Published in:

2015

By:

Pasipanodya, Jotam;
Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

Letter to the Editor

Reply to Alffenaar.

Published in:

2012

By:

Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Gumbo, Tawanda

Publication type:

Letter

Multidrug-Resistant Tuberculosis Not Due to Noncompliance but to Between-Patient Pharmacokinetic Variability.

Published in:

Journal of Infectious Diseases, 2011, v. 204, n. 12, p. 1951, doi. 10.1093/infdis/jir658

By:

Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Meek, Claudia;
Leff, Richard;
Gumbo, Tawanda

Publication type:

Article

A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin.

Published in:

2020

By:

Davids, Malika;
Pooran, Anil;
Hermann, Clemens;
Mottay, Lynelle;
Thompson, Fawziyah;
Cardenas, Jacob;
Thearith, Jinghua Gu;
Meldau, Richard;
Limberis, Jason;
Gina, Phindile;
Srivastava, Shashikant;
Calder, Bridget;
Esmail, Aliasgar;
Tomasicchio, Michele;
Blackburn, Jonathan;
Gumbo, Tawanda;
Dheda, Keertan;
Gu, Jinghua;
Koeuth, Thearith

Publication type:

journal article

A human lung challenge model to evaluate the safety and immunogenicity of PPD and live BCG.

Published in:

American Journal of Respiratory & Critical Care Medicine, 2020, v. 201, n. 10, p. E1

By:

Pooran, Anil;
Hermann, Clemens;
Mottay, Lynelle;
Thompson, Fawziyah;
Cardenas, Jacob;
Jinghua Gu;
Koeuth, Thearith;
Meldau, Richard;
Limberis, Jason;
Gina, Phindile;
Srivastava, Shashikant;
Calder, Bridget;
Esmail, Aliasgar;
Tomasicchio, Michele;
Blackburn, Jonathan;
Gumbo, Tawanda;
Dheda, Keertan

Publication type:

Article

Spatial Network Mapping of Pulmonary Multidrug-Resistant Tuberculosis Cavities Using RNA Sequencing.

Published in:

2019

By:

Dheda, Keertan;
Lenders, Laura;
Srivastava, Shashikant;
Magombedze, Gesham;
Wainwright, Helen;
Raj, Prithvi;
Bush, Stephen J.;
Pollara, Gabriele;
Steyn, Rachelle;
Davids, Malika;
Pooran, Anil;
Pennel, Timothy;
Linegar, Anthony;
McNerney, Ruth;
Moodley, Loven;
Pasipanodya, Jotam G.;
Turner, Carolin T.;
Noursadeghi, Mahdad;
Warren, Robin M.;
Wakeland, Edward

Publication type:

journal article

Drug-Penetration Gradients Associated with Acquired Drug Resistance in Patients with Tuberculosis.

Published in:

2018

By:

Dheda, Keertan;
Lenders, Laura;
Magombedze, Gesham;
Srivastava, Shashikant;
Raj, Prithvi;
Arning, Erland;
Ashcraft, Paula;
Bottiglieri, Teodoro;
Wainwright, Helen;
Pennel, Timothy;
Linegar, Anthony;
Moodley, Loven;
Pooran, Anil;
Pasipanodya, Jotam G;
Sirgel, Frederick A;
van Helden, Paul D;
Wakeland, Edward;
Warren, Robin M;
Gumbo, Tawanda

Publication type:

journal article

Transformation Morphisms and Time-to-Extinction Analysis That Map Therapy Duration From Preclinical Models to Patients With Tuberculosis: Translating From Apples to Oranges.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S349, doi. 10.1093/cid/ciy623

By:

Magombedze, Gesham;
Pasipanodya, Jotam G;
Srivastava, Shashikant;
Deshpande, Devyani;
Visser, Marianne E;
Chigutsa, Emmanuel;
McIlleron, Helen;
Gumbo, Tawanda

Publication type:

Article

The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S336, doi. 10.1093/cid/ciy626

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Nuermberger, Eric;
Lee, Pooi S;
Cirrincione, Kayle;
Dheda, Keertan;
Gumbo, Tawanda

Publication type:

Article

Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S342, doi. 10.1093/cid/ciy612

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Nuermberger, Eric;
Koeuth, Thearith;
Martin, Katherine R;
Cirrincione, Kayle N;
Lee, Pooi S;
Gumbo, Tawanda

Publication type:

Article

Linezolid-based Regimens for Multidrug-resistant Tuberculosis (TB): A Systematic Review to Establish or Revise the Current Recommended Dose for TB Treatment.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S327, doi. 10.1093/cid/ciy625

By:

Bolhuis, Mathieu S;
Akkerman, Onno W;
Sturkenboom, Marieke G G;
Ghimire, Samiksha;
Srivastava, Shashikant;
Gumbo, Tawanda;
Alffenaar, Jan-Willem C

Publication type:

Article

Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S293, doi. 10.1093/cid/ciy611

By:

Deshpande, Devyani;
Pasipanodya, Jotam G;
Mpagama, Stellah G;
Bendet, Paula;
Srivastava, Shashikant;
Koeuth, Thearith;
Lee, Pooi S;
Bhavnani, Sujata M;
Ambrose, Paul G;
Thwaites, Guy

Publication type:

Article

Gatifloxacin Pharmacokinetics/Pharmacodynamics–based Optimal Dosing for Pulmonary and Meningeal Multidrug-resistant Tuberculosis.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S274, doi. 10.1093/cid/ciy618

By:

Deshpande, Devyani;
Pasipanodya, Jotam G;
Srivastava, Shashikant;
Bendet, Paula;
Koeuth, Thearith;
Bhavnani, Sujata M;
Ambrose, Paul G;
Smythe, Wynand;
McIlleron, Helen;
Thwaites, Guy

Publication type:

Article

Ethionamide Pharmacokinetics/Pharmacodynamics-derived Dose, the Role of MICs in Clinical Outcome, and the Resistance Arrow of Time in Multidrug-resistant Tuberculosis.

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S317, doi. 10.1093/cid/ciy609

By:

Deshpande, Devyani;
Pasipanodya, Jotam G;
Mpagama, Stellah G;
Srivastava, Shashikant;
Bendet, Paula;
Koeuth, Thearith;
Lee, Pooi S;
Heysell, Scott K;
Gumbo, Tawanda

Publication type:

Article

Efficacy Versus Hepatotoxicity of High-dose Rifampin, Pyrazinamide, and Moxifloxacin to Shorten Tuberculosis Therapy Duration: There Is Still Fight in the Old Warriors Yet!

Published in:

Clinical Infectious Diseases, 2018, v. 67, p. S359, doi. 10.1093/cid/ciy627

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Magombedze, Gesham;
Gumbo, Tawanda

Publication type:

Article

Drug Concentration Thresholds Predictive of Therapy Failure and Death in Children With Tuberculosis: Bread Crumb Trails in Random Forests.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S63, doi. 10.1093/cid/ciw471

By:

Swaminathan, Soumya;
Pasipanodya, Jotam G.;
Ramachandran, Geetha;
Kumar, A. K. Hemanth;
Srivastava, Shashikant;
Deshpande, Devyani;
Nuermberger, Eric;
Gumbo, Tawanda

Publication type:

Article

A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S95, doi. 10.1093/cid/ciw474

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Nuermberger, Eric;
Pasipanodya, Jotam G.;
Swaminathan, Soumya;
Gumbo, Tawanda

Publication type:

Article

Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S88, doi. 10.1093/cid/ciw473

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Nuermberger, Eric;
Pasipanodya, Jotam G.;
Swaminathan, Soumya;
Gumbo, Tawanda

Publication type:

Article

Linezolid for Infants and Toddlers With Disseminated Tuberculosis: First Steps.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S80, doi. 10.1093/cid/ciw482

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Bush, Stephen J.;
Nuermberger, Eric;
Swaminathan, Soumya;
Gumbo, Tawanda

Publication type:

Article

A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S75, doi. 10.1093/cid/ciw472

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Pasipanodya, Jotam G.;
Thomas, Tania;
Swaminathan, Soumya;
Nuermberger, Eric;
Gumbo, Tawanda

Publication type:

Article

Optimal Clinical Doses of Faropenem, Linezolid, and Moxifloxacin in Children With Disseminated Tuberculosis: Goldilocks.

Published in:

Clinical Infectious Diseases, 2016, v. 63, p. S102, doi. 10.1093/cid/ciw483

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Pasipanodya, Jotam;
Nuermberger, Eric;
Swaminathan, Soumya;
Gumbo, Tawanda

Publication type:

Article

Meta-Analysis of Clinical Studies Supports the Pharmacokinetic Variability Hypothesis for Acquired Drug Resistance and Failure of Antituberculosis Therapy.

Published in:

Clinical Infectious Diseases, 2012, v. 55, n. 2, p. 169, doi. 10.1093/cid/cis353

By:

Pasipanodya, Jotam G.;
Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

Article

Ceftriaxone Efficacy for Mycobacterium avium Complex Lung Disease in the Hollow Fiber and Translation to Sustained Sputum Culture Conversion in Patients.

Published in:

Journal of Infectious Diseases, 2024, v. 230, n. 2, p. e230, doi. 10.1093/infdis/jiad545

By:

Deshpande, Devyani;
Magombedze, Gesham;
Boorgula, Gunavanthi D;
Chapagain, Moti;
Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

Article

Novel mutations in emb B gene of ethambutol resistant isolates of Mycobacterium tuberculosis: A preliminary report.

Published in:

Indian Journal of Medical Research, 2008, v. 128, n. 5, p. 634

By:

Jain, Amita;
Mondal, Rajesh;
Srivastava, Shashikant;
Prasad, Rajendra;
Singh, Kamlesh;
Ahuja, R. C.

Publication type:

Article

Comment on "Long-term Safety and Tolerability of Omadacycline for the Treatment of Mycobacterium abscessus Infections".

Published in:

Open Forum Infectious Diseases, 2023, v. 10, n. 8, p. 1, doi. 10.1093/ofid/ofad423

By:

Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

Article

Pharmacokinetics and pharmacodynamics of anti-tuberculosis drugs: An evaluation of in vitro, in vivo methodologies and human studies.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1063453

By:

Alffenaar, Jan-Willem C.;
de Steenwinkel, Jurriaan E. M.;
Diacon, Andreas H.;
Simonsson, Ulrika S. H.;
Srivastava, Shashikant;
Wicha, Sebastian G.

Publication type:

Article

Minocycline intra-bacterial pharmacokinetic hysteresis as a basis for pharmacologic memory and a backbone for once-a-week pan-tuberculosis therapy.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1024608

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Pasipanodya, Jotam Garaimunashe;
Gumbo, Tawanda

Publication type:

Article

Minimum inhibitory concentration, pharmacokinetics/pharmacodynamics and therapeutic drug monitoring: An integrated approach for multidrug-resistant tuberculosis.

Published in:

2015

By:

Srivastava, Shashikant

Publication type:

Opinion

embB gene mutations associated with ethambutol resistance in Indian strains of Mycobacterium tuberculosis.

Published in:

Current Science (00113891), 2006, v. 91, n. 11, p. 1512

By:

Garg, Ankita;
Srivastava, Shashikant;
Ayyagari, Archana;
Katoch, Vishwa M.;
Dhole, Tapan N.

Publication type:

Article

Repurposing Cefazolin-Avibactam for the Treatment of Drug Resistant Mycobacterium tuberculosis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.776969

By:

Srivastava, Shashikant;
Gumbo, Tawanda;
Thomas, Tania

Publication type:

Article

Cefdinir and β-Lactamase Inhibitor Independent Efficacy Against Mycobacterium tuberculosis.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.677005

By:

Srivastava, Shashikant;
Thomas, Tania;
Howe, Dave;
Malinga, Lesibana;
Raj, Prithvi;
Alffenaar, Jan-Willem;
Gumbo, Tawanda

Publication type:

Article

Comparison of Rifamycins for Efficacy Against Mycobacterium avium Complex and Resistance Emergence in the Hollow Fiber Model System.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2021.645264

By:

Boorgula, Gunavanthi D.;
Jakkula, Laxmi U. M. R.;
Gumbo, Tawanda;
Jung, Bockgie;
Srivastava, Shashikant

Publication type:

Article

Tedizolid, Faropenem, and Moxifloxacin Combination With Potential Activity Against Nonreplicating Mycobacterium tuberculosis.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.616294

By:

Srivastava, Shashikant;
Cirrincione, Kayle N.;
Deshpande, Devyani;
Gumbo, Tawanda

Publication type:

Article

Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187624

By:

Vinnard, Christopher;
Ravimohan, Shruthi;
Tamuhla, Neo;
Pasipanodya, Jotam;
Srivastava, Shashikant;
Modongo, Chawangwa;
Zetola, Nicola M.;
Weissman, Drew;
Gumbo, Tawanda;
Bisson, Gregory P.

Publication type:

Article

Sarecycline pharmacokinetics/pharmacodynamics in the hollow-fibre model of Mycobacterium avium complex: so near and yet so far.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2024, v. 79, n. 1, p. 96, doi. 10.1093/jac/dkad352

By:

Singh, Sanjay;
Boorgula, Gunavanthi D;
Aryal, Santosh;
Philley, Julie V;
Gumbo, Tawanda;
Srivastava, Shashikant

Publication type:

Article

Hollow-fibre system model of tuberculosis reproducibility and performance specifications for best practice in drug and combination therapy development.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2023, v. 78, n. 4, p. 953, doi. 10.1093/jac/dkad029

By:

Gumbo, Tawanda;
Srivastava, Shashikant;
Deshpande, Devyani;
Pasipanodya, Jotam G;
Berg, Alexander;
Romero, Klaus;
Hermann, David;
Hanna, Debra

Publication type:

Article

Repurposing drugs for treatment of Mycobacterium abscessus: a view to a kill.

Published in:

2020

By:

Gumbo, Tawanda;
Cirrincione, Kayle;
Srivastava, Shashikant

Publication type:

journal article

Duration of pretomanid/moxifloxacin/pyrazinamide therapy compared with standard therapy based on time-to-extinction mathematics.

Published in:

2020

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Magombedze, Gesham;
Zyl, Johanna van;
Cirrincione, Kayle;
Martin, Katherine;
Bendet, Paula;
Berg, Alexander;
Hanna, Debra;
Romero, Klaus;
Hermann, Dave;
Gumbo, Tawanda;
van Zyl, Johanna

Publication type:

journal article

Optimizing ethambutol dosing among HIV/tuberculosis co-infected patients: a population pharmacokinetic modelling and simulation study.

Published in:

2019

By:

Mehta, Krina;
Ravimohan, Shruthi;
Pasipanodya, Jotam G;
Srivastava, Shashikant;
Modongo, Chawangwa;
Zetola, Nicola M;
Weissman, Drew;
Ivaturi, Vijay;
Gumbo, Tawanda;
Bisson, Gregory P;
Vinnard, Christopher

Publication type:

journal article

Once-a-week tigecycline for the treatment of drug-resistant TB.

Published in:

2019

By:

Deshpande, Devyani;
Magombedze, Gesham;
Srivastava, Shashikant;
Bendet, Paula;
Lee, Pooi S;
Cirrincione, Kayle N;
Martin, Katherine R;
Dheda, Keertan;
Gumbo, Tawanda

Publication type:

journal article

Failure of the azithromycin and ethambutol combination regimen in the hollow-fibre system model of pulmonary Mycobacterium avium infection is due to acquired resistance.

Published in:

2017

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Gumbo, Tawanda

Publication type:

journal article

A programme to create short-course chemotherapy for pulmonary Mycobacterium avium disease based on pharmacokinetics/pharmacodynamics and mathematical forecasting.

Published in:

2017

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Gumbo, Tawanda

Publication type:

journal article

A novel ceftazidime/avibactam, rifabutin, tedizolid and moxifloxacin (CARTM) regimen for pulmonary Mycobacterium avium disease.

Published in:

2017

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Lee, Pooi S.;
Gumbo, Tawanda

Publication type:

journal article

A 'shock and awe' thioridazine and moxifloxacin combination-based regimen for pulmonary Mycobacterium avium-intracellulare complex disease.

Published in:

2017

By:

Srivastava, Shashikant;
Deshpande, Devyani;
Sherman, Carleton M.;
Gumbo, Tawanda

Publication type:

journal article

The discovery of ceftazidime/avibactam as an anti-Mycobacterium avium agent.

Published in:

2017

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Chapagain, Moti. L.;
Lee, Pooi S.;
Cirrincione, Kayle N.;
Pasipanodya, Jotam G.;
Gumbo, Tawanda

Publication type:

journal article

Tedizolid is highly bactericidal in the treatment of pulmonary Mycobacterium avium complex disease.

Published in:

2017

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Lee, Pooi S.;
Gumbo, Tawanda

Publication type:

journal article

Linezolid as treatment for pulmonary Mycobacterium avium disease.

Published in:

2017

By:

Deshpande, Devyani;
Srivastava, Shashikant;
Pasipanodya, Jotam G.;
Gumbo, Tawanda

Publication type:

journal article