Works by Squires, Paul E.

Results: 28

Glucose decreases extracellular adenosine levels in isolated mouse and rat pancreatic islets.

Published in:

Islets, 2012, v. 4, n. 1, p. 64, doi. 10.4161/isl.19037

By:

Yang, Gary K.;
Squires, Paul E.;
Tian, Faming;
Kieffer, Timothy J.;
Kwok, Yin Nam;
Dale, Nicholas

Publication type:

Article

Blocking connexin 43 hemichannel‐mediated ATP release reduces communication within and between tubular epithelial cells and medullary fibroblasts in a model of diabetic nephropathy.

Published in:

Diabetic Medicine, 2022, v. 39, n. 12, p. 1, doi. 10.1111/dme.14963

By:

Williams, Bethany M.;
Cliff, Chelsy L.;
Demirel, Isak;
Squires, Paul E.;
Hills, Claire E.

Publication type:

Article

Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury.

Published in:

Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01245-7

By:

Roger, Elena;
Chadjichristos, Christos E.;
Kavvadas, Panagiotis;
Price, Gareth W.;
Cliff, Chelsy L.;
Hadjadj, Safia;
Renciot, Jessy;
Squires, Paul E.;
Hills, Claire E.

Publication type:

Article

<i>'Special K'</i> and a Loss of Cell-To-Cell Adhesion in Proximal Tubule-Derived Epithelial Cells: Modulation of the Adherens Junction Complex by Ketamine.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071819

By:

Hills, Claire E.;
Jin, Tianrong;
Siamantouras, Eleftherios;
Liu, Issac K-K;
Jefferson, Kieran P.;
Squires, Paul E.

Publication type:

Article

Uncoupling of nutrient metabolism from insulin secretion by overexpression of cytosolic phospholipase A(2).

Published in:

2005

By:

Milne, Helen M.;
Burns, Chris J.;
Squires, Paul E.;
Evans, Nicholas D.;
Pickup, John;
Jones, Peter M.;
Persaud, Shanta J.

Publication type:

journal article

A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion.

Published in:

2002

By:

Persaud, Shanta J;
Roderigo-Milne, Helen M;
Squires, Paul E;
Sugden, David;
Wheeler-Jones, Caroline P D;
Marsh, Phil J;
Belin, Véronique D;
Luther, Melanie J;
Jones, Peter M

Publication type:

journal article

A Key Role for Β-Cell Cytosolic Phospholipase A[sub2] in the Maintenance of Insulin Stores But Not in the Initiation of Insulin Secretion.

Published in:

Diabetes, 2002, v. 51, n. 1, p. 98, doi. 10.2337/diabetes.51.1.98

By:

Persaud, Shanta J.;
Roderigo-Milne,, Helen M.;
Squires, Paul E.;
Sugden, David;
Wheeler-Jones, Caroline P.D.;
Marsh, Phil J.;
Belin, Véronique D.;
Luther, Melanie J.;
Jones, Peter M.

Publication type:

Article

The extracellular calcium-sensing receptor on human beta-cells negatively modulates insulin secretion.

Published in:

2000

By:

Squires, Paul E.;
Harris, Tracey E.;
Persaud, Shanta J.;
Curtis, Susan B.;
Buchan, Alison M.J.;
Jones, Peter M.;
Squires, P E;
Harris, T E;
Persaud, S J;
Curtis, S B;
Buchan, A M;
Jones, P M

Publication type:

journal article

Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets.

Published in:

1999

By:

Hauge-Evans, Astrid C.;
Squires, Paul E.;
Persaud, Shanta J.;
Jones, Peter M.;
Hauge-Evans, A C;
Squires, P E;
Persaud, S J;
Jones, P M

Publication type:

journal article

Visfatin Reduces Gap Junction Mediated Cell-to-Cell Communication in Proximal Tubule-Derived Epithelial Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2013, v. 32, n. 5, p. 1200, doi. 10.1159/000354519

By:

Hills, Claire E.;
Kerr, Michael I.;
Wall, Mark J.;
Squires, Paul E.

Publication type:

Article

Calcium-Sensing Receptor Activation Increases Cell-Cell Adhesion and β-Cell Function.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 3, p. 575, doi. 10.1159/000341439

By:

Hills, Claire E.;
Younis, Mustafa Y.G.;
Bennett, Jeanette;
Siamantouras, Eleftherios;
Liu, Kuo-Kang;
Squires, Paul E.

Publication type:

Article

TGF-β1 Mediates Glucose-evoked Up-regulation of Connexin-43 Cell-to-cell Communication in HCD-cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2009, v. 24, n. 3/4, p. 177, doi. 10.1159/000233244

By:

Hills, Claire E.;
Bland, Rosemary;
Bennett, Jeanette;
Ronco, Pierre M.;
Squires, Paul E.

Publication type:

Article

A Role for the Extracellular Calcium-Sensing Receptor in Cell-Cell Communication in Pancreatic Islets of Langerhans.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2008, v. 22, n. 5/6, p. 557, doi. 10.1159/000185540

By:

Kitsou-Mylona, Isidora;
Burns, Christopher J.;
Squires, Paul E.;
Persaud, Shanta J.;
Jones, Peter M.

Publication type:

Article

E-Cadherin and Cell Adhesion: a Role in Architecture and Function in the Pancreatic Islet.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2007, v. 20, n. 6, p. 987, doi. 10.1159/000110459

By:

Rogers, Gareth J.;
Hodgkin, Matthew N.;
Squires, Paul E.

Publication type:

Article

High Glucose Up-Regulates ENaC and SGK1 Expression in HCD-Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2006, v. 18, n. 6, p. 337, doi. 10.1159/000097611

By:

Hills, Claire E.;
Bland, Rosemary;
Bennett, Jeanette;
Ronco, Pierre M.;
Squires, Paul E.

Publication type:

Article

Quantitative investigation of calcimimetic R568 on beta cell adhesion and mechanics using AFM single-cell force spectroscopy.

Published in:

FEBS Letters, 2014, v. 588, n. 7, p. 1178, doi. 10.1016/j.febslet.2014.02.058

By:

Siamantouras, Eleftherios;
Hills, Claire E.;
Younis, Mustafa Y.G.;
Squires, Paul E.;
Liu, Kuo-Kang

Publication type:

Article

Function and expression of melatonin receptors on human pancreatic islets.

Published in:

Journal of Pineal Research, 2008, v. 44, n. 3, p. 273, doi. 10.1111/j.1600-079X.2007.00523.x

By:

Ramracheya, Reshma D.;
Muller, Dany S.;
Squires, Paul E.;
Brereton, Helen;
Sugden, David;
Cai Huang, Guo;
Amiel, Stephanie A.;
Jones, Peter M.;
Persaud, Shanta J.

Publication type:

Article

C-peptide as a therapeutic tool in diabetic nephropathy.

Published in:

2010

By:

Hills, Claire E.;
Brunskill, Nigel J.;
Squires, Paul E.

Publication type:

journal article

TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Therapeutic Intervention in Diabetic Nephropathy.

Published in:

American Journal of Nephrology, 2010, v. 31, n. 1, p. 68, doi. 10.1159/000256659

By:

Hills, Claire E.;
Squires, Paul E.

Publication type:

Article

Potassium Channels, Imidazolines, and Insulin-Secreting Cells<sup>fn1</sup>.

Published in:

Annals of the New York Academy of Sciences, 1995, v. 763, n. 1, p. 243, doi. 10.1111/j.1749-6632.1995.tb32410.x

By:

DUNNE, MARK J.;
HARDING, ELIZABETH A.;
JAGGAR, JONATHAN H.;
SQUIRES, PAUL E.;
LIANG, RIXIN;
KANE, CHARLOTTE;
JAMES, ROGER F. L.;
LONDON, NICHOLAS J. M.

Publication type:

Article

Connexin 43: A Target for the Treatment of Inflammation in Secondary Complications of the Kidney and Eye in Diabetes.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 2, p. 600, doi. 10.3390/ijms23020600

By:

Cliff, Chelsy L.;
Williams, Bethany M.;
Chadjichristos, Christos E.;
Mouritzen, Ulrik;
Squires, Paul E.;
Hills, Claire E.

Publication type:

Article

Collagen I Modifies Connexin-43 Hemichannel Activity via Integrin α2β1 Binding in TGFβ1-Evoked Renal Tubular Epithelial Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3644, doi. 10.3390/ijms22073644

By:

Potter, Joe A.;
Price, Gareth W.;
Cliff, Chelsy L.;
Green, Colin R.;
Squires, Paul E.;
Hills, Claire E.;
Campiglia, Pietro

Publication type:

Article

Danegaptide Prevents TGFβ1-Induced Damage in Human Proximal Tubule Epithelial Cells of the Kidney.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 6, p. 2809, doi. 10.3390/ijms22062809

By:

Squires, Paul E.;
Price, Gareth W.;
Mouritzen, Ulrik;
Potter, Joe A.;
Williams, Bethany M.;
Hills, Claire E.;
Huwiler, Andrea

Publication type:

Article

Blocking Connexin-43 mediated hemichannel activity protects against early tubular injury in experimental chronic kidney disease.

Published in:

Cell Communication & Signaling, 2020, v. 18, n. 1, p. 1, doi. 10.1186/s12964-020-00558-1

By:

Price, Gareth W.;
Chadjichristos, Christos E.;
Kavvadas, Panagiotis;
Tang, Sydney C. W.;
Yiu, Wai Han;
Green, Colin R.;
Potter, Joe A.;
Siamantouras, Eleftherios;
Squires, Paul E.;
Hills, Claire E.

Publication type:

Article

Comparative Effects of Efaroxan and b-Carbolines on the Secretory Activity of Rodent and Human b Cells.

Published in:

Annals of the New York Academy of Sciences, 2004, v. 1009, n. 1, p. 167, doi. 10.1196/annals.1304.019

By:

MORGAN, NOEL G.;
COOPER, E JANE;
SQUIRES, PAUL E.;
HILLS, CLAIRE E.;
PARKER, CHRISTINE A.;
HUDSON, ALAN L.

Publication type:

Article

Connexin‐mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?: Joan Mott Prize Lecture.

Published in:

Experimental Physiology, 2020, v. 105, n. 2, p. 219, doi. 10.1113/EP087770

By:

Price, Gareth W.;
Potter, Joe A.;
Williams, Bethany M.;
Cliff, Chelsy L.;
Squires, Paul E.;
Hills, Claire E.

Publication type:

Article

Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress.

Published in:

Experimental Diabetes Research, 2012, p. 1, doi. 10.1155/2012/939751

By:

Hills, Claire E.;
Bland, Rosemary;
Squires, Paul E.

Publication type:

Article

Expression and function of the extracellular calcium-sensing receptor in pancreatic β-cells.

Published in:

Archives of Physiology & Biochemistry, 2007, v. 113, n. 3, p. 98, doi. 10.1080/13813450701531185

By:

Jones, Peter M.;
Kitsou-Mylona, Isidora;
Gray, Elizabeth;
Squires, Paul E.;
Persaud, Shanta J.

Publication type:

Article