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Recombinant Human Tumor Necrosis Factor Administered as a 24-Hour Intravenous Infusion. A Phase I and Pharmacologic Study2.
Published in:
JNCI: Journal of the National Cancer Institute, 1988, v. 80, n. 13, p. 1039
By:
- Spriggs, David R.;
- Sherman, Matthew L.;
- Michie, Hamish;
- Arthur, Kristina A.;
- Imamura, Kyoko;
- Wilmore, Douglas;
- Frei, Emil;
- Kufe, Donald W.
Publication type:
Article
Sialyl-Tn serves as a potential therapeutic target for ovarian cancer.
Published in:
Journal of Ovarian Research, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13048-024-01397-1
By:
- Al-Alem, Linah;
- Prendergast, Jillian M.;
- Clark, Justin;
- Zarrella, Bianca;
- Zarrella, Dominique T.;
- Hill, Sarah J.;
- Growdon, Whitfield B.;
- Pooladanda, Venkatesh;
- Spriggs, David R.;
- Cramer, Daniel;
- Elias, Kevin M.;
- Nazer, Rawan I.;
- Skates, Steven J.;
- Behrens, Jeff;
- Dransfield, Daniel T.;
- Rueda, Bo R.
Publication type:
Article
Structural basis for antibody recognition of the proximal MUC16 ectodomain.
Published in:
Journal of Ovarian Research, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13048-024-01373-9
By:
- Lee, Kwangkook;
- Perry, Kay;
- Xu, Mengyao;
- Veillard, Irva;
- Kumar, Raj;
- Rao, Thapi Dharma;
- Rueda, Bo R;
- Spriggs, David R;
- Yeku, Oladapo O
Publication type:
Article
Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126633
By:
- Rao, Thapi D.;
- Tian, Huasong;
- Ma, Xun;
- Yan, Xiujun;
- Thapi, Sahityasri;
- Schultz, Nikolaus;
- Rosales, Nestor;
- Monette, Sebastien;
- Wang, Amy;
- Hyman, David M.;
- Levine, Douglas A.;
- Solit, David;
- Spriggs, David R.
Publication type:
Article
Galectins and Ovarian Cancer.
Published in:
Cancers, 2020, v. 12, n. 6, p. 1421, doi. 10.3390/cancers12061421
By:
- Shimada, Chisa;
- Xu, Rui;
- Al-Alem, Linah;
- Stasenko, Marina;
- Spriggs, David R.;
- Rueda, Bo R.
Publication type:
Article
The Metabolic Inhibitor CPI-613 Negates Treatment Enrichment of Ovarian Cancer Stem Cells.
Published in:
Cancers, 2019, v. 11, n. 11, p. 1678, doi. 10.3390/cancers11111678
By:
- Bellio, Chiara;
- DiGloria, Celeste;
- Spriggs, David R.;
- Foster, Rosemary;
- Growdon, Whitfield B.;
- Rueda, Bo R.
Publication type:
Article
A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission.
Published in:
Cancers, 2016, v. 8, n. 4, p. 46, doi. 10.3390/cancers8040046
By:
- O'Cearbhaill, Roisin E.;
- Ragupathi, Govind;
- Jianglong Zhu;
- Qian Wan;
- Mironov, Svetlana;
- Guangbin Yang;
- Spassova, Maria K.;
- Iasonos, Alexia;
- Kravetz, Sara;
- Ouerfelli, Ouathek;
- Spriggs, David R.;
- Danishefsky, Samuel J.;
- Sabbatini, Paul J.
Publication type:
Article
Suramin-induced weakness from hypophosphatemia and mitochondrial myopathy. Association of suramin with mitochondrial toxicity in humans.
Published in:
1994
By:
- Rago, Randall P.;
- Miles, Janet M.;
- Sufit, Robert L.;
- Spriggs, David R.;
- Wilding, George;
- Rago, R P;
- Miles, J M;
- Sufit, R L;
- Spriggs, D R;
- Wilding, G
Publication type:
journal article
Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor.
Published in:
1992
By:
- Schiller, Joan H.;
- Witt, Patricia L.;
- Storer, Barry;
- Alberti, Dona;
- Tombes, Mary Beth;
- Arzoomanian, Rhoda;
- Brown, Raymond R.;
- Proctor, Richard A.;
- Voss, Stephan D.;
- Spriggs, David R.;
- Trump, Donald L;
- Borden, Ernest C.;
- Schiller, J H;
- Witt, P L;
- Storer, B;
- Alberti, D;
- Tombes, M B;
- Arzoomanian, R;
- Brown, R R;
- Proctor, R A
Publication type:
journal article
Non-Kinase second-messenger signaling: new pathways with new promise.
Published in:
BioEssays, 2004, v. 26, n. 7, p. 730, doi. 10.1002/bies.20057
By:
- Springett, Gregory M.;
- Kawasaki, Hiroaki;
- Spriggs, David R.
Publication type:
Article
Presentation and subsequent publication rates of phase I oncology clinical trials.
Published in:
Cancer (0008543X), 2005, v. 104, n. 7, p. 1497, doi. 10.1002/cncr.21337
By:
- Luis H. Camacho;
- Jennifer Bacik;
- Alexander Cheung;
- David R. Spriggs
Publication type:
Article
Impact of race on dose selection of molecular-targeted agents in early-phase oncology trials.
Published in:
2018
By:
- Yokota, Tomoya;
- Bendell, Johanna;
- LoRusso, Patricia;
- Tsushima, Takahiro;
- Desai, Ved;
- Kenmotsu, Hirotsugu;
- Watanabe, Junichiro;
- Ono, Akira;
- Murugesan, Bhavani;
- Silva, Joseph;
- Naito, Tateaki;
- Greenberg, Jonathan;
- Kumar, Prasanna;
- Wang, Yibin;
- Jikoh, Takahiro;
- Shiga, Ryota;
- Hyman, David M.;
- Ho, Alan Loh;
- Spriggs, David R.;
- Schwartz, Gary K.
Publication type:
journal article
A phase I trial of perillyl alcohol in patients with advanced solid tumors.
Published in:
2003
By:
- Azzoli, Christopher G.;
- Miller, Vincent A.;
- Ng, Kenneth K.;
- Krug, Lee M.;
- Spriggs, David R.;
- Tong, William P.;
- Riedel, Elyn R.;
- Kris, Mark G.
Publication type:
journal article
Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-82686-3
By:
- Stasenko, Marina;
- Smith, Evan;
- Yeku, Oladapo;
- Park, Kay J.;
- Laster, Ian;
- Lee, Kwangkook;
- Walderich, Sven;
- Spriggs, Elizabeth;
- Rueda, Bo;
- Weigelt, Britta;
- Zamarin, Dmitriy;
- Rao, Thapi Dharma;
- Spriggs, David R.
Publication type:
Article
Targeting Galectin 3 illuminates its contributions to the pathology of uterine serous carcinoma.
Published in:
British Journal of Cancer, 2024, v. 130, n. 9, p. 1463, doi. 10.1038/s41416-024-02621-x
By:
- Matoba, Yusuke;
- Zarrella, Dominique T.;
- Pooladanda, Venkatesh;
- Azimi Mohammadabadi, Maryam;
- Kim, Eugene;
- Kumar, Shaan;
- Xu, Mengyao;
- Qin, Xingping;
- Ray, Lauren J;
- Devins, Kyle M.;
- Kumar, Raj;
- Kononenko, Artem;
- Eisenhauer, Eric;
- Veillard, Irva E.;
- Yamagami, Wataru;
- Hill, Sarah J.;
- Sarosiek, Kristopher A.;
- Yeku, Oladapo O.;
- Spriggs, David R.;
- Rueda, Bo R.
Publication type:
Article
A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16<sup>ecto</sup> directed chimeric antigen receptors for recurrent ovarian cancer.
Published in:
Journal of Translational Medicine, 2015, v. 13, n. 1, p. 1, doi. 10.1186/s12967-015-0460-x
By:
- Koneru, Mythili;
- O'Cearbhaill, Roisin;
- Pendharkar, Swati;
- Spriggs, David R.;
- Brentjens, Renier J.
Publication type:
Article
A phase I clinical trial of adoptive T cell therapy using IL-12 secreting MUC-16(ecto) directed chimeric antigen receptors for recurrent ovarian cancer.
Published in:
2015
By:
- Koneru, Mythili;
- O'Cearbhaill, Roisin;
- Pendharkar, Swati;
- Spriggs, David R;
- Brentjens, Renier J
Publication type:
journal article
Beyond the dose-limiting toxicity period: Dermatologic adverse events of patients on phase 1 trials of the Cancer Therapeutics Evaluation Program.
Published in:
2016
By:
- Drilon, Alexander;
- Eaton, Anne A.;
- Schindler, Katja;
- Gounder, Mrinal M.;
- Spriggs, David R.;
- Harris, Pamela;
- Ivy, S. Percy;
- Iasonos, Alexia;
- Lacouture, Mario E.;
- Hyman, David M.
Publication type:
journal article
Intravenous aflibercept in patients with platinum-resistant, advanced ovarian cancer: Results of a randomized, double-blind, phase 2, parallel-arm study.
Published in:
Cancer (0008543X), 2014, v. 120, n. 3, p. 335, doi. 10.1002/cncr.28406
By:
- Tew, William P.;
- Colombo, Nicoletta;
- Ray‐Coquard, Isabelle;
- Campo, Josep M.;
- Oza, Amit;
- Pereira, Deolinda;
- Mammoliti, Serafina;
- Matei, Daniela;
- Scambia, Giovanni;
- Tonkin, Katia;
- Shun, Zhenming;
- Sternas, Lars;
- Spriggs, David R.
Publication type:
Article
BRAF Mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer.
Published in:
Cancer (0008543X), 2013, v. 119, n. 3, p. 548, doi. 10.1002/cncr.27782
By:
- Grisham, Rachel N.;
- Iyer, Gopa;
- Garg, Karuna;
- DeLair, Deborah;
- Hyman, David M.;
- Zhou, Qin;
- Iasonos, Alexia;
- Berger, Michael F.;
- Dao, Fanny;
- Spriggs, David R.;
- Levine, Douglas A.;
- Aghajanian, Carol;
- Solit, David B.
Publication type:
Article
Improved survival for BRCA2-associated serous ovarian cancer compared with both BRCA-negative and BRCA1-associated serous ovarian cancer.
Published in:
Cancer (0008543X), 2012, v. 118, n. 15, p. 3703, doi. 10.1002/cncr.26655
By:
- Hyman, David M.;
- Zhou, Qin;
- Iasonos, Alexia;
- Grisham, Rachel N.;
- Arnold, Angela G.;
- Phillips, Mary F.;
- Bhatia, Jasmine;
- Levine, Douglas A.;
- Aghajanian, Carol;
- Offit, Kenneth;
- Barakat, Richard R.;
- Spriggs, David R.;
- Kauff, Noah D.
Publication type:
Article
Unwrapping the Implications of BRCA1 and BRCA2 Mutations in Ovarian Cancer.
Published in:
2012
By:
- Hyman, David M.;
- Spriggs, David R.
Publication type:
Editorial
Time to publication of oncology trials and why some trials are never published.
Published in:
PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0184025
By:
- Chapman, Paul B.;
- Liu, Nathan J.;
- Zhou, Qin;
- Iasonos, Alexia;
- Hanley, Sara;
- Bosl, George J.;
- Spriggs, David R.
Publication type:
Article

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