Works by Spolski, Rosanne

Results: 25

New insights into the regulation of T cells by gamma(c) family cytokines.

Published in:

2009

By:

Rochman, Yrina;
Spolski, Rosanne;
Leonard, Warren J.

Publication type:

journal article

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation.

Published in:

Nature Reviews Immunology, 2005, v. 5, n. 9, p. 688, doi. 10.1038/nri1688

By:

Leonard, Warren J.;
Spolski, Rosanne

Publication type:

Article

A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus.

Published in:

Science Immunology, 2016, v. 1, n. 5, p. 1, doi. 10.1126/sciimmunol.aaf8471

By:

West, Erin E.;
Spolski, Rosanne;
Kazemian, Majid;
Zu Xi Yu;
Kemper, Claudia;
Leonard, Warren J.

Publication type:

Article

Endothelial interleukin-21 receptor up-regulation in peripheral artery disease.

Published in:

Vascular Medicine, 2016, v. 21, n. 2, p. 99, doi. 10.1177/1358863X15621798

By:

Wang, Tao;
Cunningham, Alexis;
Houston, Kevin;
Sharma, Aditya M.;
Chen, Lingdan;
Dokun, Ayotunde O.;
Lye, R. John;
Spolski, Rosanne;
Leonard, Warren J.;
Annex, Brian H.

Publication type:

Article

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.

Published in:

Nature Immunology, 2012, v. 13, n. 12, p. 1187, doi. 10.1038/ni.2449

By:

Ring, Aaron M;
Lin, Jian-Xin;
Feng, Dan;
Mitra, Suman;
Rickert, Mathias;
Bowman, Gregory R;
Pande, Vijay S;
Li, Peng;
Moraga, Ignacio;
Spolski, Rosanne;
Özkan, Engin;
Leonard, Warren J;
Garcia, K Christopher

Publication type:

Article

IL-6 programs TH-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Published in:

Nature Immunology, 2007, v. 8, n. 9, p. 967, doi. 10.1038/ni1488

By:

Zhou, Liang;
Ivanov, Ivaylo I;
Spolski, Rosanne;
Min, Roy;
Shenderov, Kevin;
Egawa, Takeshi;
Levy, David E;
Leonard, Warren J;
Littman, Dan R

Publication type:

Article

Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer.

Published in:

Molecular Systems Biology, 2015, v. 11, n. 8, p. n/a, doi. 10.15252/msb.156172

By:

Kazemian, Majid;
Ren, Min;
Lin, Jian‐Xin;
Liao, Wei;
Spolski, Rosanne;
Leonard, Warren J

Publication type:

Article

IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B.

Published in:

2011

By:

Publicover, Jean;
Goodsell, Amanda;
Nishimura, Stephen;
Vilarinho, Silvia;
Zhi-en Wang;
Avanesyan, Lia;
Spolski, Rosanne;
Leonard, Warren J.;
Cooper, Stewart;
Baron, Jody L.;
Wang, Zhi-en

Publication type:

journal article

A new pipeline SPICE identifies novel JUN-IKZF1 composite elements.

Published in:

eLife, 2025, p. 1, doi. 10.7554/eLife.88833

By:

Peng Li;
Pulugulla, Sree;
Das, Sonali;
Jangsuk Oh;
Spolski, Rosanne;
Jian-Xin Lin;
Leonard, Warren J.

Publication type:

Article

Interleukin-21: a double-edged sword with therapeutic potential.

Published in:

2014

By:

Spolski, Rosanne;
Leonard, Warren J

Publication type:

journal article

LIM-domain-only 4 (LMO4) enhances CD8+ T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.

Published in:

Signal Transduction & Targeted Therapy, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41392-024-01915-z

By:

Schelker, Roland C.;
Fioravanti, Jessica;
Mastrogiovanni, Fabio;
Baldwin, Jeremy G.;
Rana, Nisha;
Li, Peng;
Chen, Ping;
Vadász, Timea;
Spolski, Rosanne;
Heuser-Loy, Christoph;
Slavkovic-Lukic, Dragana;
Noronha, Pedro;
Damiano, Giuseppe;
Raccosta, Laura;
Maggioni, Daniela;
Pullugula, Sree;
Lin, Jian-Xin;
Oh, Jangsuk;
Grandinetti, Patrick;
Lecce, Mario

Publication type:

Article

Complex interactions of transcription factors in mediating cytokine biology in T cells.

Published in:

Immunological Reviews, 2014, v. 261, n. 1, p. 141, doi. 10.1111/imr.12199

By:

Li, Peng;
Spolski, Rosanne;
Liao, Wei;
Leonard, Warren J.

Publication type:

Article

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-50925-6

By:

Lin, Jian-Xin;
Ge, Meili;
Liu, Cheng-yu;
Holewinski, Ronald;
Andresson, Thorkell;
Yu, Zu-Xi;
Gebregiorgis, Tesfay;
Spolski, Rosanne;
Li, Peng;
Leonard, Warren J.

Publication type:

Article

Cytokine mediators of Th17 function.

Published in:

European Journal of Immunology, 2009, v. 39, n. 3, p. 658, doi. 10.1002/eji.200839066

By:

Spolski, Rosanne;
Leonard, Warren J.

Publication type:

Article

A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases.

Published in:

European Journal of Immunology, 1986, v. 16, n. 12, p. 1643, doi. 10.1002/eji.1830161229

By:

Koga, Yasuhiro;
Caccia, Nicolette;
Toyonaga, Barry;
Spolski, Rosanne;
Yanagi, Yusuke;
Yoshikai, Yasunobu;
Mak, Tak W.

Publication type:

Article

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01477-5

By:

Jian-Xin Lin;
Ning Du;
Peng Li;
Kazemian, Majid;
Gebregiorgis, Tesfay;
Spolski, Rosanne;
Leonard, Warren J.

Publication type:

Article

IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells.

Published in:

Nature Communications, 2015, v. 6, n. 8, p. 7988, doi. 10.1038/ncomms8988

By:

Wan, Chi-Keung;
Li, Peng;
Spolski, Rosanne;
Oh, Jangsuk;
Andraski, Allison B.;
Du, Ning;
Yu, Zu-Xi;
Dillon, Christopher P.;
Green, Douglas R.;
Leonard, Warren J.

Publication type:

Article

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.

Published in:

Arthritis Research & Therapy, 2016, v. 18, p. 1, doi. 10.1186/s13075-016-1086-y

By:

Koji Sakuraba;
Akiko Oyamada;
Kenjiro Fujimura;
Rosanne Spolski;
Yukihide Iwamoto;
Leonard, Warren J.;
Yasunobu Yoshikai;
Hisakata Yamada

Publication type:

Article

MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 271, doi. 10.3390/ijms23010271

By:

Wang, Tao;
Yang, Liang;
Yuan, Mingjie;
Farber, Charles R.;
Spolski, Rosanne;
Leonard, Warren J.;
Ganta, Vijay C.;
Annex, Brian H.

Publication type:

Article

TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation.

Published in:

Science Immunology, 2025, v. 10, n. 103, p. 1, doi. 10.1126/sciimmunol.adk0073

By:

Gurram, Rama K.;
Li, Peng;
Oh, Jangsuk;
Chen, Xi;
Spolski, Rosanne;
Yao, Xianglan;
Lin, Jian-Xin;
Roy, Suyasha;
Liao, Matthew J.;
Liu, Chengyu;
Yu, Zu-Xi;
Levine, Stewart J.;
Zhu, Jinfang;
Leonard, Warren J.

Publication type:

Article

Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function.

Published in:

Science Immunology, 2023, v. 8, n. 89, p. 1, doi. 10.1126/sciimmunol.adi8217

By:

Spolski, Rosanne;
Li, Peng;
Chandra, Vivek;
Shin, Boyoung;
Goel, Shubham;
Sakamoto, Keiko;
Liu, Chengyu;
Oh, Jangsuk;
Ren, Min;
Enomoto, Yutaka;
West, Erin E.;
Christensen, Stephen M.;
Wan, Edwin C. K.;
Ge, Meili;
Lin, Jian-Xin;
Yan, Bingyu;
Kazemian, Majid;
Yu, Zu-Xi;
Nagao, Keisuke;
Vijayanand, Pandurangan

Publication type:

Article

IL-21 and T follicular helper cells.

Published in:

International Immunology, 2010, v. 22, n. 1, p. 7, doi. 10.1093/intimm/dxp112

By:

Spolski, Rosanne;
Leonard, Warren J.

Publication type:

Article

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.

Published in:

Nature, 2012, v. 491, n. 7423, p. 264, doi. 10.1038/nature11501

By:

Yoshizaki, Ayumi;
Miyagaki, Tomomitsu;
DiLillo, David J.;
Matsushita, Takashi;
Horikawa, Mayuka;
Kountikov, Evgueni I.;
Spolski, Rosanne;
Poe, Jonathan C.;
Leonard, Warren J.;
Tedder, Thomas F.

Publication type:

Article

BATF-JUN is critical for IRF4-mediated transcription in T cells.

Published in:

Nature, 2012, v. 490, n. 7421, p. 543, doi. 10.1038/nature11530

By:

Li, Peng;
Spolski, Rosanne;
Liao, Wei;
Wang, Lu;
Murphy, Theresa L.;
Murphy, Kenneth M.;
Leonard, Warren J.

Publication type:

Article

Thymic stromal lymphopoietin limits primary and recall CD8+ T-cell anti-viral responses.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.61912

By:

Ebina-Shibuya, Risa;
West, Erin E.;
Spolski, Rosanne;
Peng Li;
Jangsuk Oh;
Kazemian, Majid;
Gromer, Daniel;
Swanson, Phillip;
Ning Du;
McGavern, Dorian B.;
Leonard, Warren J.

Publication type:

Article

Works by Spolski, Rosanne

New insights into the regulation of T cells by gamma(c) family cytokines.

Interleukin-21: a modulator of lymphoid proliferation, apoptosis and differentiation.

A TSLP-complement axis mediates neutrophil killing of methicillin-resistant Staphylococcus aureus.

Endothelial interleukin-21 receptor up-regulation in peripheral artery disease.

Mechanistic and structural insight into the functional dichotomy between IL-2 and IL-15.

IL-6 programs T<sub>H</sub>-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways.

Comprehensive assembly of novel transcripts from unmapped human RNA-Seq data and their association with cancer.

IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B.

A new pipeline SPICE identifies novel JUN-IKZF1 composite elements.

Interleukin-21: a double-edged sword with therapeutic potential.

LIM-domain-only 4 (LMO4) enhances CD8<sup>+</sup> T-cell stemness and tumor rejection by boosting IL-21-STAT3 signaling.

Complex interactions of transcription factors in mediating cytokine biology in T cells.

Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation.

Cytokine mediators of Th17 function.

A human T cell-specific cDNA clone (YT16) encodes a protein with extensive homology to a family of protein-tyrosine kinases.

Critical functions for STAT5 tetramers in the maturation and survival of natural killer cells.

IL-21-mediated non-canonical pathway for IL-1β production in conventional dendritic cells.

Interleukin-21 signaling in B cells, but not in T cells, is indispensable for the development of collagen-induced arthritis in mice.

MicroRNA-30b Is Both Necessary and Sufficient for Interleukin-21 Receptor-Mediated Angiogenesis in Experimental Peripheral Arterial Disease.

TSLP acts on regulatory T cells to maintain their identity and limit allergic inflammation.

Distinct use of super-enhancer elements controls cell type–specific CD25 transcription and function.

IL-21 and T follicular helper cells.

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions.

BATF-JUN is critical for IRF4-mediated transcription in T cells.

Thymic stromal lymphopoietin limits primary and recall CD8<sup>+</sup> T-cell anti-viral responses.