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Drosophila appear resistant to trans-synaptic tau propagation.
- Published in:
- Brain Communications, 2024, v. 6, n. 4, p. 1, doi. 10.1093/braincomms/fcae256
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- Publication type:
- Article
Red carpet moments: recognition of neuroscientists by election to UK national academies.
- Published in:
- Brain Communications, 2024, v. 6, n. 4, p. 1, doi. 10.1093/braincomms/fcae203
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- Publication type:
- Article
Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation.
- Published in:
- Neuropathology & Applied Neurobiology, 2024, v. 50, n. 4, p. 1, doi. 10.1111/nan.13006
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- Publication type:
- Article
Creating and Validating a DNA Methylation-Based Proxy for Interleukin-6.
- Published in:
- 2021
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- Publication type:
- journal article
Soluble forms of tau are toxic in Alzheimer's disease.
- Published in:
- Translational Neuroscience, 2012, v. 3, n. 3, p. 223, doi. 10.2478/s13380-012-0032-y
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- Publication type:
- Article
Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 43, p. 15181, doi. 10.1523/JNEUROSCI.1542-12.2012
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- Publication type:
- Article
Inhibition of the NFAT Pathway Alleviates Amyloid Beta Neurotoxicity in a Mouse Model of Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2012, v. 32, n. 9, p. 3176, doi. 10.1523/JNEUROSCI.6439-11.2012
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- Publication type:
- Article
Amyloid β Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation.
- Published in:
- Journal of Neuroscience, 2010, v. 30, n. 7, p. 2636, doi. 10.1523/JNEUROSCI.4456-09.2010
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- Publication type:
- Article
A Reporter of Local Dendritic Translocation Shows Plaque-Related Loss of Neural System Function in APP-Transgenic Mice.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 40, p. 12636, doi. 10.1523/JNEUROSCI.1948-09.2009
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- Publication type:
- Article
In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 4, p. 862, doi. 10.1523/JNEUROSCI.3072-08.2008
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- Publication type:
- Article
Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease.
- Published in:
- FASEB Journal, 2013, v. 27, n. 8, p. 3239, doi. 10.1096/fj.13-229666
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- Publication type:
- Article
Clearing the way for tau immunotherapy in Alzheimer's disease.
- Published in:
- 2015
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- Publication type:
- Editorial
Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport.
- Published in:
- Journal of Neurochemistry, 2009, v. 111, n. 2, p. 417, doi. 10.1111/j.1471-4159.2009.06316.x
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- Publication type:
- Article
Nanoscale structure of amyloid-β plaques in Alzheimer's disease.
- Published in:
- Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-41443-3
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- Publication type:
- Article
Tau association with synaptic vesicles causes presynaptic dysfunction.
- Published in:
- Nature Communications, 2017, v. 8, n. 5, p. 15295, doi. 10.1038/ncomms15295
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- Publication type:
- Article
Targeting Tau Mitigates Mitochondrial Fragmentation and Oxidative Stress in Amyotrophic Lateral Sclerosis.
- Published in:
- Molecular Neurobiology, 2022, v. 59, n. 1, p. 683, doi. 10.1007/s12035-021-02557-w
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- Publication type:
- Article
Antidiabetic Polypill Improves Central Pathology and Cognitive Impairment in a Mixed Model of Alzheimer’s Disease and Type 2 Diabetes.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 7, p. 6130, doi. 10.1007/s12035-017-0825-7
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- Publication type:
- Article
Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease.
- Published in:
- Molecular Neurobiology, 2017, v. 54, n. 5, p. 3428, doi. 10.1007/s12035-016-9921-3
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- Publication type:
- Article
p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003.
- Published in:
- Acta Neuropathologica, 2024, v. 147, n. 1, p. 1, doi. 10.1007/s00401-023-02667-w
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- Publication type:
- Article
Selective vulnerability of inhibitory networks in multiple sclerosis.
- Published in:
- Acta Neuropathologica, 2021, v. 141, n. 3, p. 415, doi. 10.1007/s00401-020-02258-z
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- Publication type:
- Article
The physiological roles of tau and Aβ: implications for Alzheimer's disease pathology and therapeutics.
- Published in:
- Acta Neuropathologica, 2020, v. 140, n. 4, p. 417, doi. 10.1007/s00401-020-02196-w
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- Publication type:
- Article
PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins.
- Published in:
- Acta Neuropathologica, 2020, v. 139, n. 3, p. 503, doi. 10.1007/s00401-019-02114-9
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- Publication type:
- Article
Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease.
- Published in:
- Acta Neuropathologica, 2018, v. 136, n. 5, p. 747, doi. 10.1007/s00401-018-1903-2
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- Publication type:
- Article
Synapse loss in the prefrontal cortex is associated with cognitive decline in amyotrophic lateral sclerosis.
- Published in:
- Acta Neuropathologica, 2018, v. 135, n. 2, p. 213, doi. 10.1007/s00401-017-1797-4
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- Publication type:
- Article
Interactions of pathological proteins in neurodegenerative diseases.
- Published in:
- Acta Neuropathologica, 2017, v. 134, n. 2, p. 187, doi. 10.1007/s00401-017-1709-7
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- Publication type:
- Article
Soluble pathological tau in the entorhinal cortex leads to presynaptic deficits in an early Alzheimer's disease model.
- Published in:
- Acta Neuropathologica, 2014, v. 127, n. 2, p. 257, doi. 10.1007/s00401-013-1215-5
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- Publication type:
- Article
Caspase activation precedes and leads to tangles.
- Published in:
- Nature, 2010, v. 464, n. 7292, p. 1201, doi. 10.1038/nature08890
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- Publication type:
- Article
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease.
- Published in:
- Nature, 2008, v. 451, n. 7179, p. 720, doi. 10.1038/nature06616
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- Publication type:
- Article
Proceedings from the Fourth International Symposium on σ-2 Receptors: Role in Health and Disease.
- Published in:
- eNeuro, 2020, v. 7, n. 6, p. 1, doi. 10.1523/ENEURO.0317-20.2020
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- Publication type:
- Article
Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. 1, doi. 10.1186/s40478-019-0847-7
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- Publication type:
- Article
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
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- Publication type:
- Article
Post-mortem brain analyses of the Lothian Birth Cohort 1936: extending lifetime cognitive and brain phenotyping to the level of the synapse.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0232-0
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- Publication type:
- Article
Amyloid accelerates tau propagation and toxicity in a model of early Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 1, doi. 10.1186/s40478-015-0199-x
- By:
- Publication type:
- Article
Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2014, v. 2, n. 1, p. 1, doi. 10.1186/s40478-014-0146-2
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- Publication type:
- Article
High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans.
- Published in:
- eLife, 2020, p. 1, doi. 10.7554/eLife.59711
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- Publication type:
- Article
T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice.
- Published in:
- Molecular Neurodegeneration, 2011, v. 6, n. 1, p. 22, doi. 10.1186/1750-1326-6-22
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- Publication type:
- Article
Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy.
- Published in:
- Journal of Biomedical Optics, 2008, v. 13, n. 1, p. 14008, doi. 10.1117/1.2837169
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- Publication type:
- Article
Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing.
- Published in:
- Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0585-x
- By:
- Publication type:
- Article
Human Brain-Derived Aβ Oligomers Bind to Synapses and Disrupt Synaptic Activity in a Manner That Requires APP.
- Published in:
- Journal of Neuroscience, 2017, v. 37, n. 49, p. 11947, doi. 10.1523/JNEUROSCI.2009-17.2017
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- Publication type:
- Article
Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 33, p. 13300, doi. 10.1523/JNEUROSCI.0881-13.2013
- By:
- Publication type:
- Article
Loss of synaptogyrin‐3 rescues tau‐induced memory defects and synaptic loss in the presence of microglial activation: Developing topics.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.047527
- By:
- Publication type:
- Article
TMEM97 is a potential amyloid beta receptor in human Alzheimer's disease synapses: Human neuropathology/amyloid.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.041782
- By:
- Publication type:
- Article
P2‐262: A CEREBROSPINAL FLUID PANEL OF SYNAPTIC PROTEINS ACROSS THE ENTIRE ALZHEIMER'S DISEASE CONTINUUM.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P777, doi. 10.1016/j.jalz.2018.06.951
- By:
- Publication type:
- Article
INTERACTIONS OF ABETA AND TAU IN SYNAPSE LOSS.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1219, doi. 10.1016/j.jalz.2017.07.399
- By:
- Publication type:
- Article
Amyloid-beta oligomerization is associated with the generation of a typical peptide fragment fingerprint.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, n. 9, p. 996, doi. 10.1016/j.jalz.2016.03.011
- By:
- Publication type:
- Article
TAU SPREADING AND TOXICITY.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P269, doi. 10.1016/j.jalz.2016.06.2381
- By:
- Publication type:
- Article
Lack of endogenous tau permits tau spreading and protects against tau toxicity in transgenic mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 7, p. P186, doi. 10.1016/j.jalz.2015.07.159
- By:
- Publication type:
- Article
APOE4 plays a role in Abeta-mediated synapse loss in Alzheimer's disease
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Changes in the progression of amyloid deposition in APP/PS mice after overexpression of different ApoE isoforms through intraventricular injection of an adeno-associated virus serotype 4
- Published in:
- 2011
- By:
- Publication type:
- Abstract
A transgenic model of the earliest stage of Alzheimer's disease
- Published in:
- 2010
- By:
- Publication type:
- Abstract