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Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action.
Published in:
European Journal of Immunology, 2021, v. 51, n. 3, p. 544, doi. 10.1002/eji.202048747
By:
- Willsmore, Zena N.;
- Coumbe, Ben G. T.;
- Crescioli, Silvia;
- Reci, Sara;
- Gupta, Ayushi;
- Harris, Robert J.;
- Chenoweth, Alicia;
- Chauhan, Jitesh;
- Bax, Heather J.;
- McCraw, Alexa;
- Cheung, Anthony;
- Osborn, Gabriel;
- Hoffmann, Ricarda M.;
- Nakamura, Mano;
- Laddach, Roman;
- Geh, Jenny L. C.;
- MacKenzie‐Ross, Alastair;
- Healy, Ciaran;
- Tsoka, Sophia;
- Spicer, James F.
Publication type:
Article
Development of downstream processing to minimize beta-glucan impurities in GMP-manufactured therapeutic antibodies.
Published in:
Biotechnology Progress, 2016, v. 32, n. 6, p. 1494, doi. 10.1002/btpr.2359
By:
- Vigor, Kim;
- Emerson, John;
- Scott, Robert;
- Cheek, Julia;
- Barton, Claire;
- Bax, Heather J.;
- Josephs, Debra H.;
- Karagiannis, Sophia N.;
- Spicer, James F.;
- Lentfer, Heike
Publication type:
Article
IgG4 subclass antibodies impair antitumor immunity in melanoma.
Published in:
2013
By:
- Karagiannis, Panagiotis;
- Gilbert, Amy E;
- Josephs, Debra H;
- Ali, Niwa;
- Dodev, Tihomir;
- Saul, Louise;
- Correa, Isabel;
- Roberts, Luke;
- Beddowes, Emma;
- Koers, Alexander;
- Hobbs, Carl;
- Ferreira, Silvia;
- Geh, Jenny L C;
- Healy, Ciaran;
- Harries, Mark;
- Acland, Katharine M;
- Blower, Philip J;
- Mitchell, Tracey;
- Fear, David J;
- Spicer, James F
Publication type:
journal article
IgG4 subclass antibodies impair antitumor immunity in melanoma.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 4, p. 1457, doi. 10.1172/JCI65579
By:
- Karagiannis, Panagiotis;
- Gilbert, Amy E.;
- Josephs, Debra H.;
- Ali, Niwa;
- Dodev, Tihomir;
- Saul, Louise;
- Correa, Isabel;
- Roberts, Luke;
- Beddowes, Emma;
- Koers, Alexander;
- Hobbs, Carl;
- Ferreira, Silvia;
- Geh, Jenny L. C.;
- Healy, Ciaran;
- Harries, Mark;
- Acland, Katharine M.;
- Blower, Philip J.;
- Mitchell, Tracey;
- Fear, David J.;
- Spicer, James F.
Publication type:
Article
IgG4 subclass antibodies impair antitumor immunity in melanoma.
Published in:
Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 1457, doi. 10.1172/JCI65579
By:
- Karagiannis, Panagiotis;
- Gilbert, Amy E.;
- Josephs, Debra H.;
- Ali, Niwa;
- Dodev, Tihomir;
- Saul, Louise;
- Correa, Isabel;
- Roberts, Luke;
- Beddowes, Emma;
- Koers, Alexander;
- Hobbs, Carl;
- Ferreira, Silvia;
- Geh, Jenny L.C.;
- Healy, Ciaran;
- Harries, Mark;
- Acland, Katharine M.;
- Blower, Philip J.;
- Mitchell, Tracey;
- Fear, David J.;
- Spicer, James F.
Publication type:
Article
The P53-MDM2 Interaction in a Cancer-Prone Family, and the Identification of a Novel Therapeutic Target.
Published in:
Acta Oncologica, 1996, v. 35, n. 4, p. 429, doi. 10.3109/02841869609109917
By:
- Picksley, Steven M.;
- Spicer, James F.;
- Barnes, Diana M.;
- Lane, David P.
Publication type:
Article
IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin.
Published in:
Scientific Reports, 2016, p. 29736, doi. 10.1038/srep29736
By:
- Saul, Louise;
- Ilieva, Kristina M.;
- Bax, Heather J.;
- Karagiannis, Panagiotis;
- Correa, Isabel;
- Rodriguez-Hernandez, Irene;
- Josephs, Debra H.;
- Tosi, Isabella;
- Egbuniwe, Isioma U.;
- Lombardi, Sara;
- Crescioli, Silvia;
- Hobbs, Carl;
- Villanova, Federica;
- Cheung, Anthony;
- Geh, Jenny L. C.;
- Healy, Ciaran;
- Harries, Mark;
- Sanz-Moreno, Victoria;
- Fear, David J.;
- Spicer, James F.
Publication type:
Article
Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.00493
By:
- Correa, Isabel;
- Ilieva, Kristina M.;
- Crescioli, Silvia;
- Lombardi, Sara;
- Figini, Mariangela;
- Cheung, Anthony;
- Spicer, James F.;
- Tutt, Andrew N. J.;
- Nestle, Frank O.;
- Karagiannis, Panagiotis;
- Lacy, Katie E.;
- Karagiannis, Sophia N.
Publication type:
Article
Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2017.01911
By:
- Ilieva, Kristina M.;
- Cheung, Anthony;
- Mele, Silvia;
- Chiaruttini, Giulia;
- Crescioli, Silvia;
- Griffin, Merope;
- Nakamura, Mano;
- Spicer, James F.;
- Tsoka, Sophia;
- Lacy, Katie E.;
- Tutt, Andrew N. J.;
- Karagiannis, Sophia N.
Publication type:
Article
Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer.
Published in:
Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01654
By:
- Opzoomer, James W.;
- Sosnowska, Dominika;
- Anstee, Joanne E.;
- Spicer, James F.;
- Arnold, James N.
Publication type:
Article
IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype.
Published in:
Cancers, 2020, v. 12, n. 11, p. 3376, doi. 10.3390/cancers12113376
By:
- Nakamura, Mano;
- Souri, Elmira Amiri;
- Osborn, Gabriel;
- Laddach, Roman;
- Chauhan, Jitesh;
- Stavraka, Chara;
- Lombardi, Sara;
- Black, Anna;
- Khiabany, Atousa;
- Khair, Duaa O.;
- Figini, Mariangela;
- Winship, Anna;
- Ghosh, Sharmistha;
- Montes, Ana;
- Spicer, James F.;
- Bax, Heather J.;
- Josephs, Debra H.;
- Lacy, Katie E.;
- Tsoka, Sophia;
- Karagiannis, Sophia N.
Publication type:
Article
A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma.
Published in:
Cancers, 2020, v. 12, n. 4, p. 1029, doi. 10.3390/cancers12041029
By:
- Hoffmann, Ricarda M.;
- Crescioli, Silvia;
- Mele, Silvia;
- Sachouli, Eirini;
- Cheung, Anthony;
- Chui, Connie K.;
- Andriollo, Paolo;
- Jackson, Paul J. M.;
- Lacy, Katie E.;
- Spicer, James F.;
- Thurston, David E.;
- Karagiannis, Sophia N.
Publication type:
Article
Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs).
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-65860-x
By:
- Hoffmann, Ricarda M.;
- Mele, Silvia;
- Cheung, Anthony;
- Larcombe-Young, Daniel;
- Bucaite, Gintare;
- Sachouli, Eirini;
- Zlatareva, Iva;
- Morad, Hassan O. J.;
- Marlow, Rebecca;
- McDonnell, James M.;
- Figini, Mariangela;
- Lacy, Katie E.;
- Tutt, Andrew J. N.;
- Spicer, James F.;
- Thurston, David E.;
- Karagiannis, Sophia N.;
- Crescioli, Silvia
Publication type:
Article
B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.622442
By:
- Willsmore, Zena N.;
- Harris, Robert J.;
- Crescioli, Silvia;
- Hussein, Khuluud;
- Kakkassery, Helen;
- Thapa, Deepika;
- Cheung, Anthony;
- Chauhan, Jitesh;
- Bax, Heather J.;
- Chenoweth, Alicia;
- Laddach, Roman;
- Osborn, Gabriel;
- McCraw, Alexa;
- Hoffmann, Ricarda M.;
- Nakamura, Mano;
- Geh, Jenny L.;
- MacKenzie-Ross, Alastair;
- Healy, Ciaran;
- Tsoka, Sophia;
- Spicer, James F.
Publication type:
Article
IgE Antibodies against Cancer: Efficacy and Safety.
Published in:
Antibodies (2073-4468), 2020, v. 9, n. 4, p. 55, doi. 10.3390/antib9040055
By:
- Chauhan, Jitesh;
- McCraw, Alex J.;
- Nakamura, Mano;
- Osborn, Gabriel;
- Sow, Heng Sheng;
- Cox, Vivienne F.;
- Stavraka, Chara;
- Josephs, Debra H.;
- Spicer, James F.;
- Karagiannis, Sophia N.;
- Bax, Heather J.
Publication type:
Article
Functionally active Fc Mutant antibodies recognizing cancer antigens generated rapidly at high Yields.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01112
By:
- Ilieva, Kristina M.;
- Fazekas-Singer, Judit;
- Achkova, Daniela Y.;
- Dodev, Tihomir S.;
- Mele, Silvia;
- Crescioli, Silvia;
- Bax, Heather J.;
- Cheung, Anthony;
- Karagiannis, Panagiotis;
- Correa, Isabel;
- Figini, Mariangela;
- Marlow, Rebecca;
- Josephs, Debra H.;
- Beavil, Andrew J.;
- Maher, John;
- Spicer, James F.;
- Jensen-Jarolim, Erika;
- Tutt, Andrew N.;
- Karagiannis, Sophia N.
Publication type:
Article
The role of the HGF/Met axis in mesothelioma.
Published in:
Biochemical Society Transactions, 2016, v. 44, n. 2, p. 363, doi. 10.1042/BST20150252
By:
- Thayaparan, Thivyan;
- Spicer, James F.;
- Maher, John
Publication type:
Article
Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome.
Published in:
Cells (2073-4409), 2020, v. 9, n. 7, p. 1631, doi. 10.3390/cells9071631
By:
- Bax, Heather J.;
- Chauhan, Jitesh;
- Stavraka, Chara;
- Khiabany, Atousa;
- Nakamura, Mano;
- Pellizzari, Giulia;
- Ilieva, Kristina M.;
- Lombardi, Sara;
- Gould, Hannah J.;
- Corrigan, Christopher J.;
- Till, Stephen J.;
- Katugampola, Sidath;
- Jones, Paul S.;
- Barton, Claire;
- Winship, Anna;
- Ghosh, Sharmistha;
- Montes, Ana;
- Josephs, Debra H.;
- Spicer, James F.;
- Karagiannis, Sophia N.
Publication type:
Article
EGFR inhibitors in non-small cell lung cancer (NSCLC): the emerging role of the dual irreversible EGFR/HER2 inhibitor BIBW 2992.
Published in:
2010
By:
- Spicer, James;
- Rudman, Sarah;
- Spicer, James F;
- Rudman, Sarah M
Publication type:
journal article
AllergoOncology: Expression platform development and functional profiling of an anti‐HER2 IgE antibody.
Published in:
Allergy, 2019, v. 74, n. 10, p. 1985, doi. 10.1111/all.13818
By:
- Ilieva, Kristina M.;
- Fazekas‐Singer, Judit;
- Bax, Heather J.;
- Crescioli, Silvia;
- Montero‐Morales, Laura;
- Mele, Silvia;
- Sow, Heng Sheng;
- Stavraka, Chara;
- Josephs, Debra H.;
- Spicer, James F.;
- Steinkellner, Herta;
- Jensen‐Jarolim, Erika;
- Tutt, Andrew N. J.;
- Karagiannis, Sophia N.
Publication type:
Article

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