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Recommendations for the clinical interpretation and reporting of copy number gains using gene panel NGS analysis in routine diagnostics.
Published in:
2019
By:
- Eijkelenboom, Astrid;
- Tops, Bastiaan B. J.;
- van den Berg, Anke;
- van den Brule, Adrianus J. C.;
- Dinjens, Winand N. M.;
- Dubbink, Hendrikus J.;
- ter Elst, Arja;
- Geurts-Giele, Willemina R. R.;
- Groenen, Patricia J. T. A.;
- Groenendijk, Floris H.;
- Heideman, Daniëlle A. M.;
- Huibers, Manon M. H.;
- Huijsmans, Cornelis J. J.;
- Jeuken, Judith W. M.;
- van Kempen, Léon C.;
- Korpershoek, Esther;
- Kroeze, Leonie I.;
- de Leng, Wendy W. J.;
- van Noesel, Carel J. M.;
- Speel, Ernst-Jan M.
Publication type:
journal article
Next-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?
Published in:
Reviews in Medical Virology, 2012, v. 22, n. 2, p. 88, doi. 10.1002/rmv.714
By:
- Olthof, Nadine C.;
- Straetmans, Jos M.J.A.A.;
- Snoeck, Robert;
- Ramaekers, Frans C.S.;
- Kremer, Bernd;
- Speel, Ernst-Jan M.
Publication type:
Article
Emerging role of human polyomaviruses 6 and 7 in human cancers.
Published in:
Infectious Agents & Cancer, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13027-021-00374-3
By:
- Klufah, Faisal;
- Mobaraki, Ghalib;
- Liu, Dan;
- Alharbi, Raed A.;
- Kurz, Anna Kordelia;
- Speel, Ernst Jan M.;
- Winnepenninckx, Véronique;
- zur Hausen, Axel
Publication type:
Article
Proximity ligation‐based sequencing for the identification of human papillomavirus genomic integration sites in formalin‐fixed paraffin embedded oropharyngeal squamous cell carcinomas.
Published in:
Journal of Medical Virology, 2024, v. 96, n. 8, p. 1, doi. 10.1002/jmv.29837
By:
- Demers, Imke;
- Balaji, Harini;
- Feitsma, Harma;
- Stelloo, Ellen;
- Swennenhuis, Joost;
- Sergeeva, Irina;
- Wuerdemann, Nora;
- van den Hout, Mari F. C. M.;
- Wagner, Steffen;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Huebbers, Christian U.;
- Speel, Ernst‐Jan M.
Publication type:
Article
Use of the HPV MLPA assay in cervical cytology for the prediction of high grade lesions.
Published in:
Journal of Medical Virology, 2013, v. 85, n. 8, p. 1386, doi. 10.1002/jmv.23629
By:
- Litjens, Rogier J.N.T.M.;
- Theelen, Wendy;
- van de Pas, Yvonne;
- Ossel, Jessica;
- Reijans, Martin;
- Simons, Guus;
- Speel, Ernst‐Jan M.;
- Slangen, Brigitte F.M.;
- Ramaekers, Frans C.S.;
- Kruitwagen, Roy F.P.M.;
- Hopman, Anton H.N.
Publication type:
Article
Association of RANKL and EGFR gene expression with bone metastases in patients with metastatic non-small cell lung cancer.
Published in:
Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1145001
By:
- Brouns, Anita J. W. M.;
- Hendriks, Lizza E. L.;
- den Berge, Iris J. Robbesom-van;
- Driessen, Annemariek J. H. M.;
- Roemen, Guido M. J. M.;
- van Herpen, Britt L. J.;
- Dekkers, Zoë;
- Heitzer, Bas;
- Leunissen, Daphne J. G.;
- Moonen, Laura;
- Lunde, Ragnar;
- Westenend, Marcel;
- van Driel, Marjolein;
- Speel, Ernst-Jan M.;
- Dingemans, Anne-Marie C.
Publication type:
Article
Unique Metastatic Patterns in Neuroendocrine Neoplasms of Different Primary Origin.
Published in:
Neuroendocrinology, 2021, v. 111, n. 11, p. 1111, doi. 10.1159/000513249
By:
- Hermans, Bregtje C.M.;
- de Vos-Geelen, Judith;
- Derks, Jules L.;
- Latten, Loes;
- Liem, Ing Han;
- van der Zwan, Jan Maarten;
- Speel, Ernst-Jan M.;
- Dercksen, M. Wouter;
- Dingemans, Anne-Marie C.
Publication type:
Article
Identification of MicroRNAs Differentially Expressed in Lung Carcinoid Subtypes and Progression.
Published in:
Neuroendocrinology, 2015, v. 101, n. 3, p. 246, doi. 10.1159/000381454
By:
- Rapa, Ida;
- Votta, arianna;
- Felice, Barbara;
- Righi, Luisella;
- Giorcelli, Jessica;
- Scarpa, aldo;
- Speel, Ernst-Jan M.;
- Scagliotti, Giorgio V.;
- Papotti, Mauro;
- Volante, Marco
Publication type:
Article
Spectral Karyotypic and Comparative Genomic Analysis of the Endocrine Pancreatic Tumor Cell Line BON-1.
Published in:
Neuroendocrinology, 2010, v. 91, n. 2, p. 131, doi. 10.1159/000254483
By:
- Lopez, Juan R.;
- Claessen, Sandra M. H.;
- Macville, Merryn V. E.;
- Albrechts, Jozefa C. M.;
- Skogseid, Britt;
- Speel, Ernst-Jan M.
Publication type:
Article
Human papillomavirus reduces the prognostic value of nodal involvement in tonsillar squamous cell carcinomas.
Published in:
Laryngoscope, 2009, v. 119, n. 10, p. 1951, doi. 10.1002/lary.20593
By:
- Straetmans, Jos M. J. A. A.;
- Olthof, Nadine;
- Mooren, Jeroen J.;
- de Jong, Jos;
- Speel, Ernst-Jan M.;
- Kremer, Bernd
Publication type:
Article
MEN1 Gene Mutation and Reduced Expression Are Associated With Poor Prognosis in Pulmonary Carcinoids.
Published in:
2014
By:
- Swarts, Dorian R A;
- Scarpa, Aldo;
- Corbo, Vincenzo;
- Van Criekinge, Wim;
- van Engeland, Manon;
- Gatti, Gaia;
- Henfling, Mieke E R;
- Papotti, Mauro;
- Perren, Aurel;
- Ramaekers, Frans C S;
- Speel, Ernst-Jan M;
- Volante, Marco
Publication type:
Journal Article
Comprehensive Analysis of HPV16 Integration in OSCC Reveals No Significant Impact of Physical Status on Viral Oncogene and Virally Disrupted Human Gene Expression.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088718
By:
- Olthof, Nadine C.;
- Speel, Ernst-Jan M.;
- Kolligs, Jutta;
- Haesevoets, Annick;
- Henfling, Mieke;
- Ramaekers, Frans C. S.;
- Preuss, Simon F.;
- Drebber, Uta;
- Wieland, Ulrike;
- Silling, Steffi;
- Lam, Wan L.;
- Vucic, Emily A.;
- Kremer, Bernd;
- Klussmann, Jens-P.;
- Huebbers, Christian U.
Publication type:
Article
Integration of HPV6 and Downregulation of AKR1C3 Expression Mark Malignant Transformation in a Patient with Juvenile-Onset Laryngeal Papillomatosis.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057207
By:
- Huebbers, Christian Ulrich;
- Preuss, Simon Florian;
- Kolligs, Jutta;
- Vent, Julia;
- Stenner, Markus;
- Wieland, Ulrike;
- Silling, Steffi;
- Drebber, Uta;
- Speel, Ernst-Jan M.;
- Klussmann, Jens Peter
Publication type:
Article
Frequent detection of human polyomavirus 6 in keratoacanthomas.
Published in:
Diagnostic Pathology, 2016, v. 11, p. 1, doi. 10.1186/s13000-016-0509-z
By:
- Beckervordersandforth, Jan;
- Pujari, Sreedhar;
- Rennspiess, Dorit;
- Speel, Ernst Jan M.;
- Winnepenninckx, Véronique;
- Diaz, Carlos;
- Weyers, Wolfgang;
- Haugg, Anke Maria;
- Kurz, Anna Kordelia;
- zur ^Hausen, Axel
Publication type:
Article
Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.
Published in:
2009
By:
- Henopp, Tobias;
- Anlauf, Martin;
- Schmitt, Anja;
- Schlenger, Regina;
- Zalatnai, Attila;
- Couvelard, Anne;
- Ruszniewski, Philippe;
- Schaps, Klaus-Peter;
- Jonkers, Yvonne M H;
- Speel, Ernst-Jan M;
- Pellegata, Natalia S;
- Heitz, Philipp U;
- Komminoth, Paul;
- Perren, Aurel;
- Klöppel, Günter
Publication type:
journal article
Potent inhibitory effects of type I interferons on human adrenocortical carcinoma cell growth.
Published in:
2006
By:
- van Koetsveld, Peter M;
- Vitale, Giovanni;
- de Herder, Wouter W;
- Feelders, Richard A;
- van der Wansem, Katy;
- Waaijers, Marlijn;
- van Eijck, Casper H J;
- Speel, Ernst-Jan M;
- Croze, Ed;
- van der Lely, Aart-Jan;
- Lamberts, Steven W J;
- Hofland, Leo J
Publication type:
journal article
Tumor control of cervical lymph node metastases of unknown primary origin: the impact of the radiotherapy target volume.
Published in:
European Archives of Oto-Rhino-Laryngology, 2020, v. 277, n. 6, p. 1753, doi. 10.1007/s00405-020-05867-2
By:
- Straetmans, Jos M. J. A. A.;
- Stuut, Marijn;
- Wagemakers, Sanne;
- Hoebers, Frank;
- Kaanders, Johannes H. A. M.;
- Speel, Ernst Jan M.;
- Melchers, Willem J. G.;
- Slootweg, Piet;
- Kremer, Bernd;
- Lacko, Martin;
- Takes, Robert P.
Publication type:
Article
DNA and RNA Alterations Associated with Colorectal Peritoneal Metastases: A Systematic Review.
Published in:
Cancers, 2023, v. 15, n. 2, p. 549, doi. 10.3390/cancers15020549
By:
- Heuvelings, Danique J. I.;
- Wintjens, Anne G. W. E.;
- Luyten, Julien;
- Wilmink, Guus E. W. A.;
- Moonen, Laura;
- Speel, Ernst-Jan M.;
- de Hingh, Ignace H. J. T.;
- Bouvy, Nicole D.;
- Peeters, Andrea
Publication type:
Article
Evaluation Criteria for Chromosome Instability Detection by FISH to Predict Malignant Progression in Premalignant Glottic Laryngeal Lesions.
Published in:
Cancers, 2022, v. 14, n. 13, p. N.PAG, doi. 10.3390/cancers14133260
By:
- Bergshoeff, Verona E.;
- Balkenhol, Maschenka C. A.;
- Haesevoets, Annick;
- Ruland, Andrea;
- Chenault, Michelene N.;
- Nelissen, Rik C.;
- Peutz, Carine J.;
- Clarijs, Ruud;
- Van der Laak, Jeroen A. W. M.;
- Takes, Robert P.;
- Van den Brekel, Michiel W.;
- Van Velthuysen, Marie-Louise F.;
- Ramaekers, Frans C. S.;
- Kremer, Bernd;
- Speel, Ernst-Jan M.
Publication type:
Article
Upfront Surgery vs. Primary Chemoradiation in an Unselected, Bicentric Patient Cohort with Oropharyngeal Squamous Cell Carcinoma—A Matched-Pair Analysis.
Published in:
Cancers, 2021, v. 13, n. 21, p. 5265, doi. 10.3390/cancers13215265
By:
- Zimmermann, Philipp H.;
- Stuut, Marijn;
- Wuerdemann, Nora;
- Möllenhoff, Kathrin;
- Suchan, Malte;
- Eckel, Hans;
- Wolber, Philipp;
- Sharma, Shachi J.;
- Kämmerer, Fabian;
- Langer, Christine;
- Wittekindt, Claus;
- Wagner, Steffen;
- Kremer, Bernd;
- Speel, Ernst Jan M.;
- Klussmann, Jens P.
Publication type:
Article
Cell-Free HPV-DNA as a Biomarker for Oropharyngeal Squamous Cell Carcinoma—A Step Towards Personalized Medicine?
Published in:
Cancers, 2020, v. 12, n. 10, p. 2997, doi. 10.3390/cancers12102997
By:
- Wuerdemann, Nora;
- Jain, Rishabh;
- Adams, Anne;
- Speel, Ernst-Jan M.;
- Wagner, Steffen;
- Joosse, Simon A.;
- Klussmann, Jens P.
Publication type:
Article
High Prevalence of Human Polyomavirus 7 in Cholangiocarcinomas and Adjacent Peritumoral Hepatocytes: Preliminary Findings.
Published in:
Microorganisms, 2020, v. 8, n. 8, p. 1125, doi. 10.3390/microorganisms8081125
By:
- Klufah, Faisal;
- Mobaraki, Ghalib;
- Chteinberg, Emil;
- Alharbi, Raed A.;
- Winnepenninckx, Véronique;
- Speel, Ernst Jan M.;
- Rennspiess, Dorit;
- Olde Damink, Steven W.;
- Neumann, Ulf P.;
- Kurz, Anna Kordelia;
- Samarska, Iryna;
- zur Hausen, Axel
Publication type:
Article
Presence of Human Papillomavirus and Epstein–Barr Virus, but Absence of Merkel Cell Polyomavirus, in Head and Neck Cancer of Non-Smokers and Non-Drinkers.
Published in:
Frontiers in Oncology, 2021, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.560434
By:
- Mulder, Frans J.;
- Klufah, Faisal;
- Janssen, Famke M. E.;
- Farshadpour, Farzaneh;
- Willems, Stefan M.;
- de Bree, Remco;
- zur Hausen, Axel;
- van den Hout, Mari F. C. M.;
- Kremer, Bernd;
- Speel, Ernst-Jan M.
Publication type:
Article
Differential Orthopedia Homeobox expression in pulmonary carcinoids is associated with changes in DNA methylation.
Published in:
International Journal of Cancer, 2022, v. 150, n. 12, p. 1987, doi. 10.1002/ijc.33939
By:
- Moonen, Laura;
- Mangiante, Lise;
- Leunissen, Daphne J. G.;
- Lap, Lisa M. V.;
- Gabriel, Aurelie;
- Hillen, Lisa M.;
- Roemen, Guido M.;
- Koch, Alexander;
- van Engeland, Manon;
- Dingemans, Anne‐Marie C.;
- Foll, Matthieu;
- Alcala, Nicolas;
- Fernandez‐Cuesta, Lynnette;
- Derks, Jules L.;
- Speel, Ernst‐Jan M.
Publication type:
Article
In‐depth molecular analysis of combined and co‐primary pulmonary large cell neuroendocrine carcinoma and adenocarcinoma.
Published in:
International Journal of Cancer, 2022, v. 150, n. 5, p. 802, doi. 10.1002/ijc.33853
By:
- Hermans, Bregtje C. M.;
- Derks, Jules L.;
- Hillen, Lisa M.;
- van der Baan, Irene;
- van den Broek, Esther C.;
- von der Thüsen, Jan H.;
- van Suylen, Robert‐Jan;
- Atmodimedjo, Peggy N.;
- den Toom, T. Dorine;
- Coumans‐Stallinga, Cecile;
- Timens, Wim;
- Dinjens, Winand N. M.;
- Dubbink, Hendrikus J.;
- Speel, Ernst‐Jan M.;
- Dingemans, Anne‐Marie C.
Publication type:
Article
External Quality Assessment on Molecular Tumor Profiling with Circulating Tumor DNA-Based Methodologies Routinely Used in Clinical Pathology within the COIN Consortium.
Published in:
Clinical Chemistry, 2024, v. 70, n. 5, p. 759, doi. 10.1093/clinchem/hvae014
By:
- van der Leest, Paul;
- Rozendal, Pim;
- Hinrichs, John;
- Noesel, Carel J M van;
- Zwaenepoel, Karen;
- Deiman, Birgit;
- Huijsmans, Cornelis J J;
- Eijk, Ronald van;
- Speel, Ernst Jan M;
- Haastert, Rick J van;
- Ligtenberg, Marjolijn J L;
- Schaik, Ron H N van;
- Jansen, Maurice P H M;
- Dubbink, Hendrikus J;
- Leng, Wendy W de;
- Leers, Mathie P G;
- Tamminga, Menno;
- van den Broek, Daan;
- Kempen, Léon C van;
- Schuuring, Ed
Publication type:
Article
Dutch National Round Robin Trial on Plasma-Derived Circulating Cell-Free DNA Extraction Methods Routinely Used in Clinical Pathology for Molecular Tumor Profiling.
Published in:
Clinical Chemistry, 2022, v. 68, n. 7, p. 963, doi. 10.1093/clinchem/hvac069
By:
- van der Leest, Paul;
- Ketelaar, Emma M.;
- van Noesel, Carel J. M.;
- van den Broek, Daan;
- van Boerdonk, Robert A. A.;
- Deiman, Birgit;
- Rifaela, Naomi;
- van der Geize, Robert;
- Huijsmans, Cornelis J. J.;
- Speel, Ernst Jan M.;
- Geerlings, Maartje J.;
- van Schaik, Ron H. N.;
- Jansen, Maurice P. H. M.;
- Dane-Vogelaar, Ria;
- Driehuis, Else;
- Leers, Mathie P. G.;
- Sidorenkov, Grigory;
- Tamminga, Menno;
- van Kempen, Léon C.;
- Schuuring, Ed
Publication type:
Article
Abdominal inflammatory myofibroblastic tumour: Clinicopathological and molecular analysis of 20 cases, highlighting potential therapeutic targets.
Published in:
Histopathology, 2024, v. 84, n. 5, p. 794, doi. 10.1111/his.15122
By:
- Vernemmen, Astrid I P;
- Samarska, Iryna V;
- Speel, Ernst‐Jan M;
- Riedl, Robert G;
- Goudkade, Danny;
- de Bruïne, Adriaan P;
- Wouda, Siep;
- van Marion, Arienne M;
- Verlinden, Ivana V;
- van Lijnschoten, Ineke;
- Friederich, Pieter;
- Winnepenninckx, Véronique J L;
- zur Hausen, Axel;
- Sciot, Raf M E;
- van den Hout, Mari F C M
Publication type:
Article
Cutaneous metastases of internal malignancies: a single‐institution experience.
Published in:
Histopathology, 2022, v. 81, n. 3, p. 329, doi. 10.1111/his.14705
By:
- Vernemmen, Astrid I P;
- Li, Xiaofei;
- Roemen, Guido M J M;
- Speel, Ernst‐Jan M;
- Kubat, Bela;
- Hausen, Axel zur;
- Winnepenninckx, Véronique J L;
- Samarska, Iryna V
Publication type:
Article
Nuclear translocation of β-catenin and decreased expression of epithelial cadherin in human papillomavirus-positive tonsillar cancer: an early event in human papillomavirus-related tumour progression?
Published in:
Histopathology, 2011, v. 58, n. 7, p. 1117, doi. 10.1111/j.1365-2559.2011.03805.x
By:
- Stenner, Markus;
- Yosef, Basima;
- Huebbers, Christian U.;
- Preuss, Simon F.;
- Dienes, Hans-Peter;
- Speel, Ernst-Jan M.;
- Odenthal, Margarete;
- Klussmann, Jens P.
Publication type:
Article
Modified UroVysion scoring criteria increase the urothelial carcinoma detection rate in cases of equivocal urinary cytology.
Published in:
Histopathology, 2011, v. 58, n. 7, p. 1048, doi. 10.1111/j.1365-2559.2011.03859.x
By:
- Huysentruyt, Clément J. R.;
- Baldewijns, Marcella M.;
- Rüland, Andrea M.;
- Tonk, Ronald J. W.;
- Vervoort, Peter S. A. M.;
- Smits, Kim M.;
- van de Beek, Cees;
- Speel, Ernst-Jan M.
Publication type:
Article
Simultaneous assessment of DNA ploidy and biomarker expression in paraffin-embedded tissue sections.
Published in:
Histopathology, 2010, v. 57, n. 1, p. 14, doi. 10.1111/j.1365-2559.2010.03599.x
By:
- Fleskens, Stijn J. H. M.;
- Takes, Robert P.;
- Otte-Höller, Irene;
- van Doesburg, Lisanne;
- Smeets, Annemieke;
- Speel, Ernst-Jan M.;
- Slootweg, Pieter J.;
- van der Laak, Jeroen A. W. M.
Publication type:
Article
p16<sup>INK4A</sup> overexpression is frequently detected in tumour-free tonsil tissue without association with HPV.
Published in:
Histopathology, 2010, v. 56, n. 7, p. 957, doi. 10.1111/j.1365-2559.2010.03576.x
By:
- Klingenberg, Boris;
- Hafkamp, Harriët C;
- Haesevoets, Annick;
- Manni, Johannes J.;
- Slootweg, Pieter J.;
- Weissenborn, Soenke J.;
- Klussmann, Jens P.;
- Speel, Ernst-Jan M.
Publication type:
Article
An exploration of pathways involved in lung carcinoid progression using gene expression profiling.
Published in:
Carcinogenesis, 2013, v. 34, n. 12, p. 2726, doi. 10.1093/carcin/bgt271
By:
- Swarts, Dorian R.A.;
- Van Neste, Leander;
- Henfling, Mieke E.R.;
- Eijkenboom, Ivo;
- Eijk, Paul P.;
- van Velthuysen, Marie-Louise;
- Vink, Aryan;
- Volante, Marco;
- Ylstra, Bauke;
- Van Criekinge, Wim;
- van Engeland, Manon;
- Ramaekers, Frans C.S.;
- Speel, Ernst-Jan M.
Publication type:
Article
Molecular evidence for a clonal relationship between multiple lesions in patients with unknown primary adenocarcinoma.
Published in:
International Journal of Cancer, 2008, v. 123, n. 6, p. 1292, doi. 10.1002/ijc.23616
By:
- Speel, Ernst-Jan M.;
- van de Wouw, Agnes J.;
- Claessen, Sandra M.H.;
- Haesevoets, Annick;
- Hopman, Anton H.N.;
- van der Wurff, Anneke A.M.;
- Osieka, Rainhardt;
- Buettner, Reinhard;
- Hillen, Harry F.P.;
- Ramaekers, Frans C.S.
Publication type:
Article
Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas.
Published in:
International Journal of Cancer, 2008, v. 122, n. 12, p. 2656, doi. 10.1002/ijc.23458
By:
- Hafkamp, Harriët C.;
- Manni, J.J.;
- Haesevoets, A.;
- Voogd, A.C.;
- Schepers, M.;
- Bot, F.J.;
- Hopman, A.H.N.;
- Ramaekers, F.C.S.;
- Speel, Ernst-Jan M.
Publication type:
Article
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen.
Published in:
International Journal of Cancer, 2007, v. 121, n. 11, p. 2465, doi. 10.1002/ijc.22980
By:
- Smeets, Serge J.;
- Hesselink, Albertus T.;
- Speel, Ernst-Jan M.;
- Haesevoets, Annick;
- Snijders, Peter J.F.;
- Pawlita, Michael;
- Meijer, Chris J.L.M.;
- Braakhuis, Boudewijn J.M.;
- Leemans, C. René;
- Brakenhoff, Ruud H.
Publication type:
Article
Combined analysis of HPV-DNA, p16 and EGFR expression to predict prognosis in oropharyngeal cancer.
Published in:
International Journal of Cancer, 2007, v. 120, n. 8, p. 1731, doi. 10.1002/ijc.22355
By:
- Reimers, Niklas;
- Kasper, Hans U.;
- Weissenborn, Soenke J.;
- Stützer, Hartmut;
- Preuss, Simon F.;
- Hoffmann, Thomas K.;
- Speel, Ernst Jan M.;
- Dienes, Hans P.;
- Pfister, Herbert J.;
- Guntinas-Lichius, Orlando;
- Klussmann, Jens P.
Publication type:
Article
HPV in situ hybridization: Impact of different protocols on the detection of integrated HPV.
Published in:
International Journal of Cancer, 2005, v. 115, n. 3, p. 419, doi. 10.1002/ijc.20862
By:
- Hopman, Anton H.N.;
- Kamps, Miriam A.;
- Smedts, Frank;
- Speel, Ernst-Jan M.;
- Herrington, C. Simon;
- Ramaekers, Frans C.S.
Publication type:
Article
Differences in Imiquimod Treatment Outcome in Two Patients with Bowenoid Papulosis Containing Either Episomal or Integrated Human Papillomavirus 16.
Published in:
2007
By:
- Lucker, Georges P. H.;
- Speel, Ernst-Jan M.;
- Creytens, David H. K.;
- van Geest, Adrienne J.;
- Peeters, Jolanda H. M.;
- Claessen, Sandra M. H.;
- Vermeulen, Anton H. M.;
- Pauwels, Patrick;
- Meulemans, Els V.
Publication type:
Letter
WHO grade I meningiomas that show regrowth after gamma knife radiosurgery often show 1p36 loss.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95956-x
By:
- Damen, Pim J. J.;
- Bulthuis, Vincent J.;
- Hanssens, Patrick E. J.;
- Lie, Suan Te;
- Fleischeuer, Ruth;
- Melotte, Veerle;
- Wouters, Kim A.;
- Ruland, Andrea;
- Beckervordersandforth, Jan;
- Speel, Ernst Jan M.
Publication type:
Article
Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV‐negative tumors is an indicator of poor prognosis.
Published in:
International Journal of Cancer, 2019, v. 144, n. 10, p. 2465, doi. 10.1002/ijc.31954
By:
- Huebbers, Christian U.;
- Verhees, Femke;
- Poluschkin, Leonard;
- Olthof, Nadine C.;
- Kolligs, Jutta;
- Siefer, Oliver G.;
- Henfling, Mieke;
- Ramaekers, Frans C.S.;
- Preuss, Simon F.;
- Beutner, Dirk;
- Seehawer, Julia;
- Drebber, Uta;
- Korkmaz, Yüksel;
- Lam, Wan L.;
- Vucic, Emily A.;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Speel, Ernst‐Jan M.
Publication type:
Article
Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines.
Published in:
International Journal of Cancer, 2015, v. 136, n. 5, p. E207, doi. 10.1002/ijc.29112
By:
- Olthof, Nadine C.;
- Huebbers, Christian U.;
- Kolligs, Jutta;
- Henfling, Mieke;
- Ramaekers, Frans C.S.;
- Cornet, Iris;
- Lent‐Albrechts, Josefa A.;
- Stegmann, Alexander P.A.;
- Silling, Steffi;
- Wieland, Ulrike;
- Carey, Thomas E.;
- Walline, Heather M.;
- Gollin, Susanne M.;
- Hoffmann, Thomas K.;
- Winter, Johan;
- Kremer, Bernd;
- Klussmann, Jens P.;
- Speel, Ernst‐Jan M.
Publication type:
Article
Fluorescence in situ hybridization and qPCR to detect Merkel cell polyomavirus physical status and load in Merkel cell carcinomas.
Published in:
International Journal of Cancer, 2014, v. 135, n. 12, p. 2804, doi. 10.1002/ijc.28931
By:
- Haugg, Anke M.;
- Rennspiess, Dorit;
- Hausen, Axel zur;
- Speel, Ernst‐Jan M.;
- Cathomas, Gieri;
- Becker, Jürgen C.;
- Schrama, David
Publication type:
Article
P16<sup>INK4A</sup> immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias.
Published in:
International Journal of Cancer, 2014, v. 134, n. 9, p. 2108, doi. 10.1002/ijc.28534
By:
- Mooren, Jeroen J.;
- Gültekin, Sibel E.;
- Straetmans, Jos M.J.A.A.;
- Haesevoets, Annick;
- Peutz‐Kootstra, Carine J.;
- Huebbers, Christian U.;
- Dienes, Hans P.;
- Wieland, Ulrike;
- Ramaekers, Frans C.S.;
- Kremer, Bernd;
- Speel, Ernst‐Jan M.;
- Klussmann, Jens P.
Publication type:
Article
Chromosome stability in tonsillar squamous cell carcinoma is associated with HPV16 integration and indicates a favorable prognosis.
Published in:
International Journal of Cancer, 2013, v. 132, n. 8, p. 1781, doi. 10.1002/ijc.27846
By:
- Mooren, Jeroen J.;
- Kremer, Bernd;
- Claessen, Sandra M.H.;
- Voogd, Adri C.;
- Bot, Fredrik J.;
- Peter Klussmann, J.;
- Huebbers, Christian U.;
- Hopman, Anton H.N.;
- Ramaekers, Frans C.S.;
- Speel, Ernst‐Jan M.
Publication type:
Article
A new multiparameter assay to assess HPV 16/18, viral load and physical status together with gain of telomerase genes in HPV-related cancers.
Published in:
International Journal of Cancer, 2010, v. 126, n. 4, p. 959, doi. 10.1002/ijc.24844
By:
- Theelen, Wendy;
- Reijans, Martin;
- Simons, Guus;
- Ramaekers, Frans C.S.;
- Speel, Ernst-Jan M.;
- Hopman, Anton H.N.
Publication type:
Article
Detection of PTCH1 Copy-Number Variants in Mosaic Basal Cell Nevus Syndrome.
Published in:
Biomedicines, 2024, v. 12, n. 2, p. 330, doi. 10.3390/biomedicines12020330
By:
- Roemen, Guido M. J. M.;
- Theunissen, Tom E. J.;
- Hoezen, Ward W. J.;
- Steyls, Anja R. M.;
- Paulussen, Aimee D. C.;
- Mosterd, Klara;
- Rahikkala, Elisa;
- zur Hausen, Axel;
- Speel, Ernst Jan M.;
- van Geel, Michel
Publication type:
Article
Additional parameters to improve the prognostic value of the 8th edition of the UICC classification for human papillomavirus‐related oropharyngeal tumors.
Published in:
Head & Neck, 2022, v. 44, n. 8, p. 1799, doi. 10.1002/hed.27084
By:
- Straetmans, Jos M. J. A. A.;
- Stuut, Marijn;
- Lacko, Martin;
- Hoebers, Frank;
- Speel, Ernst‐Jan M.;
- Kremer, Bernd
Publication type:
Article
Evidence for different molecular parameters in head and neck squamous cell carcinoma of nonsmokers and nondrinkers: Systematic review and meta‐analysis on HPV, p16, and TP53.
Published in:
Head & Neck, 2021, v. 43, n. 1, p. 303, doi. 10.1002/hed.26513
By:
- Mulder, Frans J.;
- Pierssens, Damiana D. C. G.;
- Baijens, Laura W. J.;
- Kremer, Bernd;
- Speel, Ernst‐Jan M.
Publication type:
Article

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