Works matching AU Southall, Noel

Results: 70

AI-driven discovery of synergistic drug combinations against pancreatic cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56818-6

By:

Pourmousa, Mohsen;
Jain, Sankalp;
Barnaeva, Elena;
Jin, Wengong;
Hochuli, Joshua;
Itkin, Zina;
Maxfield, Travis;
Melo-Filho, Cleber;
Thieme, Andrew;
Wilson, Kelli;
Klumpp-Thomas, Carleen;
Michael, Sam;
Southall, Noel;
Jaakkola, Tommi;
Muratov, Eugene N.;
Barzilay, Regina;
Tropsha, Alexander;
Ferrer, Marc;
Zakharov, Alexey V.

Publication type:

Article

AI-driven discovery of synergistic drug combinations against pancreatic cancer.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56818-6

By:

Pourmousa, Mohsen;
Jain, Sankalp;
Barnaeva, Elena;
Jin, Wengong;
Hochuli, Joshua;
Itkin, Zina;
Maxfield, Travis;
Melo-Filho, Cleber;
Thieme, Andrew;
Wilson, Kelli;
Klumpp-Thomas, Carleen;
Michael, Sam;
Southall, Noel;
Jaakkola, Tommi;
Muratov, Eugene N.;
Barzilay, Regina;
Tropsha, Alexander;
Ferrer, Marc;
Zakharov, Alexey V.

Publication type:

Article

DPTIP, a newly identified potent brain penetrant neutral sphingomyelinase 2 inhibitor, regulates astrocyte-peripheral immune communication following brain inflammation.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-36144-2

By:

Rojas, Camilo;
Barnaeva, Elena;
Thomas, Ajit G.;
Hu, Xin;
Southall, Noel;
Marugan, Juan;
Chaudhuri, Amrita Datta;
Yoo, Seung-Wan;
Hin, Niyada;
Stepanek, Ondrej;
Wu, Ying;
Zimmermann, Sarah C.;
Gadiano, Alexandra G.;
Tsukamoto, Takashi;
Rais, Rana;
Haughey, Norman;
Ferrer, Marc;
Slusher, Barbara S.

Publication type:

Article

Predicting liver cytosol stability of small molecules.

Published in:

Journal of Cheminformatics, 2020, v. 12, n. 1, p. 1, doi. 10.1186/s13321-020-00426-7

By:

Shah, Pranav;
Siramshetty, Vishal B.;
Zakharov, Alexey V.;
Southall, Noel T.;
Xu, Xin;
Nguyen, Dac-Trung

Publication type:

Article

Cell-based high-throughput screening identifies galactocerebrosidase enhancers as potential small-molecule therapies for Krabbe's disease.

Published in:

Journal of Neuroscience Research, 2016, v. 94, n. 11, p. 1231, doi. 10.1002/jnr.23875

By:

Jang, Dae Song;
Ye, Wenjuan;
Guimei, Tian;
Solomon, Melani;
Southall, Noel;
Hu, Xin;
Marugan, Juan;
Ferrer, Marc;
Maegawa, Gustavo H.B.

Publication type:

Article

The use or generation of biomedical data and existing medicines to discover and establish new treatments for patients with rare diseases - recommendations of the IRDiRC Data Mining and Repurposing Task Force.

Published in:

2019

By:

Southall, Noel T;
Natarajan, Madhusudan;
Lau, Lilian Pek Lian;
Jonker, Anneliene Hechtelt;
Deprez, Benoît;
Guilliams, Tim;
Hunter, Lawrence;
Rademaker, Carin MA;
Hivert, Virginie;
Ardigò, Diego;
on behalf of the IRDiRC Data Mining and Repurposing Task Force;
Cavalla, David;
Colvis, Christine;
Hettne, Kristina;
't-Hoen, Peter-Bram;
Kant, Caroline;
Krischer, Jeffrey;
Marin, Frédéric;
Quintana, Jordi;
Rademaker, Carin MA

Publication type:

journal article

Rapid antimicrobial susceptibility test for identification of new therapeutics and drug combinations against multidrug-resistant bacteria.

Published in:

Emerging Microbes & Infections, 2016, v. 5, n. 11, p. e116, doi. 10.1038/emi.2016.123

By:

Sun, Wei;
Weingarten, Rebecca A;
Xu, Miao;
Southall, Noel;
Dai, Sheng;
Shinn, Paul;
Sanderson, Philip E;
Williamson, Peter R;
Frank, Karen M;
Zheng, Wei

Publication type:

Article

Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0130796

By:

Lee, Jonathan A.;
Shinn, Paul;
Jaken, Susan;
Oliver, Sarah;
Willard, Francis S.;
Heidler, Steven;
Peery, Robert B.;
Oler, Jennifer;
Chu, Shaoyou;
Southall, Noel;
Dexheimer, Thomas S.;
Smallwood, Jeffrey;
Huang, Ruili;
Guha, Rajarshi;
Jadhav, Ajit;
Cox, Karen;
Austin, Christopher P.;
Simeonov, Anton;
Sittampalam, G. Sitta;
Husain, Saba

Publication type:

Article

A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of gsp.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090766

By:

Bhattacharyya, Nisan;
Hu, Xin;
Chen, Catherine Z.;
Mathews Griner, Lesley A.;
Zheng, Wei;
Inglese, James;
Austin, Christopher P.;
Marugan, Juan J.;
Southall, Noel;
Neumann, Susanne;
Northup, John K.;
Ferrer, Marc;
Collins, Michael T.

Publication type:

Article

Rapid Identification of Antifungal Compounds against Exserohilum rostratum Using High Throughput Drug Repurposing Screens.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0070506

By:

Sun, Wei;
Park, Yoon-Dong;
Sugui, Janyce A.;
Fothergill, Annette;
Southall, Noel;
Shinn, Paul;
McKew, John C.;
Kwon-Chung, Kyung J.;
Zheng, Wei;
Williamson, Peter R.

Publication type:

Article

Inhibition of Ceramide Metabolism Sensitizes Human Leukemia Cells to Inhibition of BCL2-Like Proteins.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054525

By:

Casson, Lavona;
Howell, Lauren;
Mathews, Lesley A.;
Ferrer, Marc;
Southall, Noel;
Guha, Rajarshi;
Keller, Jonathan M.;
Thomas, Craig;
Siskind, Leah J.;
Beverly, Levi J.

Publication type:

Article

High Throughput Screening for Small Molecule Therapy for Gaucher Disease Using Patient Tissue as the Source of Mutant Glucocerebrosidase.

Published in:

PLoS ONE, 2012, v. 7, n. 1, p. 1, doi. 10.1371/journal.pone.0029861

By:

Goldin, Ehud;
Wei Zheng;
Motabar, Omid;
Southall, Noel;
Jae Hyuk Choi;
Marugan, Juan;
Austin, Christopher P.;
Sidransky, Ellen

Publication type:

Article

Novel Patient Cell-Based HTS Assay for Identification of Small Molecules for a Lysosomal Storage Disease.

Published in:

PLoS ONE, 2011, v. 6, n. 12, p. 1, doi. 10.1371/journal.pone.0029504

By:

Haifeng Geng;
Whiteley, Grace;
Ribbens, Jameson;
Wei Zheng;
Southall, Noel;
Xin Hu;
Marugan, Juan J.;
Ferrer, Marc;
Maegawa, Gustavo H. B.

Publication type:

Article

RXFP2 Small Molecule Agonists: Potential Therapeutics for Osteoporosis.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2398

By:

Esteban‐Lopez, Maria;
Wilson, Kenneth;
Myhr, Courtney;
Kaftanovskaya, Elena;
Henderson, Mark;
Southall, Noel;
Hu, Xin;
Barnaeva, Elena;
Ferrer, Marc;
Kim, David;
Ye, Wenjuan;
Morello, Roy;
Agoulnik, Irina;
Marugan, Juan;
Agoulnik, Alexander

Publication type:

Article

Structure–Activity Relationships of a Negative Allosteric Modulator of the D3 Dopamine Receptor and Investigation of its Binding Site.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2589

By:

Moritz, Amy E.;
Madaras, Nora S.;
Inbody, Laura R.;
Kelley, Amber M.;
Gandhi, Disha M.;
Akano, Emmanuel;
Lee, Kuo H.;
Free, R. B.;
Hu, Xin;
Southall, Noel T.;
Ferrer, Marc;
Shi, Lei;
Frankowski, Kevin J.;
Sibley, David R.

Publication type:

Article

Optimization of ML321: a D2 dopamine receptor‐selective antagonist for the treatment of neuropsychiatric disorders.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02466

By:

Rocereta, Julia;
Free, R.;
Dulcey Garcia, Andres;
Southall, Noel;
Shi, Lei;
Lane, J.;
Wetsel, William;
Marugan, Juan;
Sibley, David

Publication type:

Article

Therapeutic effects of a small molecule agonist of the relaxin receptor ML290 in liver fibrosis.

Published in:

FASEB Journal, 2019, v. 33, n. 11, p. 12435, doi. 10.1096/fj.201901046R

By:

Kaftanovskaya, Elena M.;
Hooi Hooi Ng;
Soula, Mariluz;
Rivas, Bryan;
Myhr, Courtney;
Ho, Brian A.;
Cervantes, Briana A.;
Shupe, Thomas D.;
Devarasetty, Mahesh;
Xin Hu;
Xin Xu;
Patnaik, Samarjit;
Wilson, Kenneth J.;
Barnaeva, Elena;
Ferrer, Marc;
Southall, Noel T.;
Marugan, Juan J.;
Bishop, Colin E.;
Agoulnik, Irina U.;
Agoulnik, Alexander I.

Publication type:

Article

Identification of a novel, highly potent D3 dopamine receptor‐selective agonist (662.8).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.662.8

By:

Moritz, Amy;
Free, R.;
Conroy, Jennie;
Weiner, Warren;
Doyle, Trevor;
Southall, Noel;
Ferrer, Marc;
Javitch, Jonathan;
Aubé, Jeffrey;
Frankowski, Kevin;
Sibley, David

Publication type:

Article

Discovery and characterization of a G protein‐biased agonist of the D2 dopamine receptor (662.7).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.662.7

By:

Chun, Lani;
Free, R.;
Moritz, Amy;
Conroy, Jennie;
Meade, Julie;
Xiao, Jingbo;
Dulcey, Andrés;
Vekariya, Rakesh;
Ferrer, Marc;
Javitch, Jonathan;
Beuming, Thijs;
Shi, Lei;
Southall, Noel;
Marugan, Juan;
Aubé, Jeff;
Frankowski, Kevin;
Sibley, David

Publication type:

Article

Identification of allosteric modulators of the D2 dopamine receptor (662.6).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.662.6

By:

Free, R;
Southall, Noel;
Doyle, Trevor;
Meade, Julie;
Conroy, Jennie;
Javitch, Jonathan;
Ferrer, Marc;
Sibley, David

Publication type:

Article

High‐throughput screening for novel allosteric modulators of the D1 dopamine receptor (662.4).

Published in:

FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.662.4

By:

Conroy, Jennie;
Free, R.;
Doyle, Trevor;
Southall, Noel;
Hazelwood, Lisa;
Miller, Nicole;
Ferrer, Marc;
Sibley, David

Publication type:

Article

Discovery, characterization, and optimization of highly selective D2 dopaminergic antagonists.

Published in:

FASEB Journal, 2013, v. 27, p. 655.7, doi. 10.1096/fasebj.27.1_supplement.655.7

By:

Free, R. Benjamin;
Xiao, Jingbo;
Doyle, Trevor;
Conroy, Jennie;
Titus, Steve;
Bryant‐Genevier, Melanie;
Southall, Noel;
Hu, Xin;
Ferrer, Marc;
Javitch, Jonathan A;
Marugan, Juan J;
Sibley, David R

Publication type:

Article

Identification of a novel dopaminergic agonist that selectively activates the D3 dopamine receptor.

Published in:

FASEB Journal, 2013, v. 27, p. 655.6, doi. 10.1096/fasebj.27.1_supplement.655.6

By:

Moritz, Amy E.;
Free, R. Benjamin;
Conroy, Jennie;
Doyle, Trevor;
Southall, Noel;
Ferrer, Marc;
Donthamsetti, Prashant;
Javitch, Jonathan A.;
Sibley, David R.

Publication type:

Article

A Multiplex Calcium Assay for Identification of GPCR Agonists and Antagonists.

Published in:

Assay & Drug Development Technologies, 2010, v. 8, n. 3, p. 367, doi. 10.1089/adt.2009.0245

By:

Ke Liu;
Noel Southall;
Steve A. Titus;
James Inglese;
Robert L. Eskay;
Paul Shinn;
Christopher P. Austin;
Markus A. Heilig;
Wei Zheng

Publication type:

Article

A Cell-Based Assay for IBαStabilization Using A Two-Color Dual Luciferase-Based Sensor.

Published in:

Assay & Drug Development Technologies, 2007, v. 5, n. 1, p. 85, doi. 10.1089/adt.2006.048

By:

R. Eric Davis;
Ya-Qin Zhang;
Noel Southall;
Louis M. Staudt;
Christopher P. Austin;
James Inglese;
Douglas S. Auld

Publication type:

Article

Machine intelligence in healthcare—perspectives on trustworthiness, explainability, usability, and transparency.

Published in:

NPJ Digital Medicine, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s41746-020-0254-2

By:

Cutillo, Christine M.;
Sharma, Karlie R.;
Foschini, Luca;
Kundu, Shinjini;
Mackintosh, Maxine;
Mandl, Kenneth D.;
MI in Healthcare Workshop Working Group;
Beck, Tyler;
Collier, Elaine;
Colvis, Christine;
Gersing, Kenneth;
Gordon, Valery;
Jensen, Roxanne;
Shabestari, Behrouz;
Southall, Noel

Publication type:

Article

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.

Published in:

Stem Cells Translational Medicine, 2016, v. 5, n. 5, p. 613, doi. 10.5966/sctm.2015-0170

By:

THORNE, NATASHA;
MALIK, NASIR;
SHAH, SONIA;
ZHAO, JEAN;
CLASS, BRADLEY;
AGUISANDA, FRANCIS;
SOUTHALL, NOEL;
XIA, MENGHANG;
MCKEW, JOHN C.;
RAO, MAHENDRA;
WEI ZHENG

Publication type:

Article

High-Throughput Screening to Identify Compounds That Increase Fragile X Mental Retardation Protein Expression in Neural Stem Cells Differentiated From Fragile X Syndrome Patient-Derived Induced Pluripotent Stem Cells.

Published in:

Stem Cells Translational Medicine, 2015, v. 4, n. 7, p. 800, doi. 10.5966/sctm.2014-0278

By:

KUMARI, DAMAN;
SWAROOP, MANJU;
SOUTHALL, NOEL;
WENWEI HUANG;
WEI ZHENG;
USDIN, KAREN

Publication type:

Article

Sunitinib promotes myogenic regeneration and mitigates disease progression in the mdx mouse model of Duchenne muscular dystrophy.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 13, p. 2120, doi. 10.1093/hmg/ddz044

By:

Fontelonga, Tatiana M;
Jordan, Brennan;
Nunes, Andreia M;
Barraza-Flores, Pamela;
Bolden, Nicholas;
Wuebbles, Ryan D;
Griner, Lesley Mathews;
Hu, Xin;
Ferrer, Marc;
Marugan, Juan;
Southall, Noel;
Burkin, Dean J

Publication type:

Article

High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 6, p. 1551, doi. 10.1093/hmg/ddt542

By:

Ketley, Ami;
Chen, Catherine Z.;
Li, Xin;
Arya, Sukrat;
Robinson, Thelma E.;
Granados-Riveron, Javier;
Udosen, Inyang;
Morris, Glenn E.;
Holt, Ian;
Furling, Denis;
Chaouch, Soraya;
Haworth, Ben;
Southall, Noel;
Shinn, Paul;
Zheng, Wei;
Austin, Christopher P.;
Hayes, Christopher J.;
Brook, J. David

Publication type:

Article

An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD).

Published in:

Journal of Biomedical Semantics, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13326-020-00232-y

By:

Zhu, Qian;
Nguyen, Dac-Trung;
Grishagin, Ivan;
Southall, Noel;
Sid, Eric;
Pariser, Anne

Publication type:

Article

A Novel Brain Penetrant NPS Receptor Antagonist, NCGC00185684, Blocks Alcohol-Induced ERK-Phosphorylation in the Central Amygdala and Decreases Operant Alcohol Self-Administration in Rats.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 24, p. 10132, doi. 10.1523/JNEUROSCI.4742-12.2013

By:

Thorsell, Annika;
Tapocik, Jenica D.;
Ke Liu;
Zook, Michelle;
Bell, Lauren;
Flanigan, Meghan;
Patnaik, Samarjit;
Marugan, Juan;
Damadzic, Ruslan;
Dehdashti, Seameen J.;
Schwandt, Melanie L.;
Southall, Noel;
Austin, Christopher P.;
Eskay, Robert;
Ciccocioppo, Roberto;
Wei Zheng;
Heilig, Markus

Publication type:

Article

A patient safety knowledge graph supporting vaccine product development.

Published in:

BMC Medical Informatics & Decision Making, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12911-023-02409-8

By:

Simms, Andrew M.;
Kanakia, Anshul;
Sipra, Muhammad;
Dutta, Bhaskar;
Southall, Noel

Publication type:

Article

Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer.

Published in:

2018

By:

Vilimas, Tomas;
Wang, Amy Q.;
Patnaik, Samarjit;
Hughes, Emma A.;
Singleton, Marc D.;
Knotts, Zachary;
Li, Dandan;
Frankowski, Kevin;
Schlomer, Jerome J.;
Guerin, Theresa M.;
Springer, Stephanie;
Drennan, Catherine;
Dextras, Christopher;
Wang, Chen;
Gilbert, Debra;
Southall, Noel;
Ferrer, Marc;
Huang, Sui;
Kozlov, Serguei;
Marugan, Juan

Publication type:

journal article

High throughput cell-based assay for identification of glycolate oxidase inhibitors as a potential treatment for Primary Hyperoxaluria Type 1.

Published in:

Scientific Reports, 2016, p. 34060, doi. 10.1038/srep34060

By:

Wang, Mengqiao;
Xu, Miao;
Long, Yan;
Fargue, Sonia;
Southall, Noel;
Hu, Xin;
McKew, John C.;
Danpure, Christopher J.;
Zheng, Wei

Publication type:

Article

A High-Throughput, Multi-Cell Phenotype Assay for the Identification of Novel Inhibitors of Chemotaxis/Migration.

Published in:

Scientific Reports, 2016, p. 22273, doi. 10.1038/srep22273

By:

Liao, Xin-Hua;
Meena, Netra Pal;
Southall, Noel;
Liu, Lunhua;
Swaroop, Manju;
Zhang, Arina Li;
Xiang, Jan Jian;
Parent, Carole A.;
Zheng, Wei;
Kimmel, Alan R.

Publication type:

Article

Comprehensive characterization of cytochrome P450 isozyme selectivity across chemical libraries.

Published in:

Nature Biotechnology, 2009, v. 27, n. 11, p. 1050, doi. 10.1038/nbt.1581

By:

Veith, Henrike;
Southall, Noel;
Huang, Ruili;
James, Tim;
Fayne, Darren;
Artemenko, Natalia;
Min Shen;
Inglese, James;
Austin, Christopher P.;
Lloyd, David G.;
Auld, Douglas S.

Publication type:

Article

Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening.

Published in:

Environmental Health Perspectives, 2008, v. 116, n. 3, p. 284, doi. 10.1289/ehp.10727

By:

Menghang Xia;
Ruili Huang;
Witt, Kristine L.;
Southall, Noel;
Fostel, Jennifer;
Ming-Hsuang Cho;
Jadhav, Ajit;
Smith, Cynthia S.;
Inglese, James;
Portier, Christopher J.;
Tice, Raymond R.;
Austin, Christopher P.

Publication type:

Article

A novel quantitative high-throughput screen identifies drugs that both activate SUMO conjugation via the inhibition of microRNAs 182 and 183 and facilitate neuroprotection in a model of oxygen and glucose deprivation.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2016, v. 36, n. 2, p. 426, doi. 10.1177/0271678X15609939

By:

Bernstock, Joshua D.;
Yang-ja Lee;
Peruzzotti-Jametti, Luca;
Southall, Noel;
Johnson, Kory R.;
Maric, Dragan;
Volpe, Giulio;
Kouznetsova, Jennifer;
Wei Zheng;
Pluchino, Stefano;
Hallenbeck, John M.

Publication type:

Article

COPI Complex Is a Regulator of Lipid Homeostasis.

Published in:

PLoS Biology, 2008, v. 6, n. 11, p. e292, doi. 10.1371/journal.pbio.0060292

By:

Beller, Mathias;
Sztalryd, Carole;
Southall, Noel;
Bell, Ming;
Jäckle, Herbert;
Auld, Douglas S.;
Oliver, Brian

Publication type:

Article

Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90944-7

By:

Singh, Anju;
Dashynam, Myagmarjav;
Chim, Bryan;
Escobar, Thelma M.;
Liu, Xiuhuai;
Hu, Xin;
Patnaik, Samarjit;
Xu, Xin;
Southall, Noel;
Marugan, Juan;
Jadhav, Ajit;
Lazarevic, Vanja;
Muljo, Stefan A.;
Ferrer, Marc

Publication type:

Article

A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-85279-2

By:

Khaled, Houda G.;
Feng, Hongxuan;
Hu, Xin;
Sun, Xin;
Zheng, Wang;
Li, Pan P.;
Rudnicki, Dobrila D.;
Ye, Wenjuan;
Chen, Yu-Chi;
Southall, Noel;
Marugan, Juan;
Ross, Christopher A.;
Ferrer, Marc;
Henderson, Mark J.;
Margolis, Russell L.

Publication type:

Article

Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-77327-0

By:

Siramshetty, Vishal B.;
Shah, Pranav;
Kerns, Edward;
Nguyen, Kimloan;
Yu, Kyeong Ri;
Kabir, Md;
Williams, Jordan;
Neyra, Jorge;
Southall, Noel;
Nguyễn, Ðắc-Trung;
Xu, Xin

Publication type:

Article

An Orally Efficacious Thyrotropin Receptor Ligand Inhibits Growth and Metastatic Activity of Thyroid Cancers.

Published in:

Journal of Clinical Endocrinology & Metabolism, 2024, v. 109, n. 9, p. 2306, doi. 10.1210/clinem/dgae114

By:

Sarkar, Rhitajit;
Bolel, Priyanka;
Kapoor, Abhijeet;
Eliseeva, Elena;
Dulcey, Andrés E;
Templin, Jay S;
Wang, Amy Q;
Xu, Xin;
Southall, Noel;
Klubo-Gwiezdzinska, Joanna;
Neumann, Susanne;
Marugan, Juan J;
Gershengorn, Marvin C

Publication type:

Article

Validation of a Natural Language Machine Learning Model for Safety Literature Surveillance.

Published in:

Drug Safety, 2024, v. 47, n. 1, p. 71, doi. 10.1007/s40264-023-01367-4

By:

Park, Jiyoon;
Djelassi, Malek;
Chima, Daniel;
Hernandez, Robert;
Poroshin, Vladimir;
Iliescu, Ana-Maria;
Domalik, Douglas;
Southall, Noel

Publication type:

Article

Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing.

Published in:

Molecular Informatics, 2017, v. 36, n. 4, p. n/a, doi. 10.1002/minf.201600126

By:

Sun, Hongmao;
Huang, Ruili;
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Scientific Reports, 2014, p. 1, doi. 10.1038/srep03743

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Nature Communications, 2013, v. 4, n. 6, p. 1953, doi. 10.1038/ncomms2953

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Xiao, Jingbo;
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