Works by Soukup, Ondrej

Results: 87
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    A-series agent A-234: initial in vitro and in vivo characterization.

    Published in:
    Archives of Toxicology, 2024, v. 98, n. 4, p. 1135, doi. 10.1007/s00204-024-03689-3
    By:
    • Hrabinova, Martina;
    • Pejchal, Jaroslav;
    • Hepnarova, Vendula;
    • Muckova, Lubica;
    • Junova, Lucie;
    • Opravil, Jakub;
    • Zdarova Karasova, Jana;
    • Rozsypal, Tomas;
    • Dlabkova, Alzbeta;
    • Rehulkova, Helena;
    • Kucera, Tomas;
    • Vecera, Zbyněk;
    • Caisberger, Filip;
    • Schmidt, Monika;
    • Soukup, Ondrej;
    • Jun, Daniel
    Publication type:
    Article
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    A-agents, misleadingly known as "Novichoks": a narrative review.

    Published in:
    Archives of Toxicology, 2023, v. 97, n. 10, p. 2587, doi. 10.1007/s00204-023-03571-8
    By:
    • Opravil, Jakub;
    • Pejchal, Jaroslav;
    • Finger, Vladimir;
    • Korabecny, Jan;
    • Rozsypal, Tomas;
    • Hrabinova, Martina;
    • Muckova, Lubica;
    • Hepnarova, Vendula;
    • Konecny, Jan;
    • Soukup, Ondrej;
    • Jun, Daniel
    Publication type:
    Article
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    Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.

    Published in:
    Archives of Toxicology, 2021, v. 95, n. 3, p. 985, doi. 10.1007/s00204-021-02981-w
    By:
    • Gorecki, Lukas;
    • Hepnarova, Vendula;
    • Karasova, Jana Zdarova;
    • Hrabinova, Martina;
    • Courageux, Charlotte;
    • Dias, José;
    • Kucera, Tomas;
    • Kobrlova, Tereza;
    • Muckova, Lubica;
    • Prchal, Lukas;
    • Malinak, David;
    • Jun, Daniel;
    • Musilek, Kamil;
    • Worek, Franz;
    • Nachon, Florian;
    • Soukup, Ondrej;
    • Korabecny, Jan
    Publication type:
    Article
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    Methylacridinium and its Cholinergic Properties.

    Published in:
    Neurotoxicity Research, 2009, v. 16, n. 4, p. 372, doi. 10.1007/s12640-009-9071-8
    By:
    • Soukup, Ondrej;
    • Proska, Jan;
    • Binder, Jiri;
    • Karasova, Jana Zdarova;
    • Tobin, Gunnar;
    • Jun, Daniel;
    • Marek, Jan;
    • Musílek, Kamil;
    • Fusek, Josef;
    • Kuca, Kamil
    Publication type:
    Article
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    In vitro investigating of anticancer activity of new 7-MEOTA-tacrine heterodimers.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 877, doi. 10.1080/14756366.2019.1593159
    By:
    • Janockova, Jana;
    • Korabecny, Jan;
    • Plsikova, Jana;
    • Babkova, Katerina;
    • Konkolova, Eva;
    • Kucerova, Dana;
    • Vargova, Jana;
    • Koval, Jan;
    • Jendzelovsky, Rastislav;
    • Fedorocko, Peter;
    • Kasparkova, Jana;
    • Brabec, Viktor;
    • Rosocha, Jan;
    • Soukup, Ondrej;
    • Hamulakova, Slavka;
    • Kuca, Kamil;
    • Kozurkova, Maria
    Publication type:
    Article
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    Synthesis and biological assessment of KojoTacrines as new agents for Alzheimer's disease therapy.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2019, v. 34, n. 1, p. 163, doi. 10.1080/14756366.2018.1538136
    By:
    • Dgachi, Youssef;
    • Martin, Hélène;
    • Malek, Rim;
    • Jun, Daniel;
    • Janockova, Jana;
    • Sepsova, Vendula;
    • Soukup, Ondrej;
    • Iriepa, Isabel;
    • Moraleda, Ignacio;
    • Maalej, Emna;
    • Carreiras, M. Carmo;
    • Refouvelet, Bernard;
    • Chabchoub, Fakher;
    • Marco-Contelles, José;
    • Ismaili, Lhassane
    Publication type:
    Article
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    Structure-Guided Design of N -Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.

    Published in:
    International Journal of Molecular Sciences, 2023, v. 24, n. 11, p. 9124, doi. 10.3390/ijms24119124
    By:
    • Svobodova, Barbora;
    • Pulkrabkova, Lenka;
    • Panek, Dawid;
    • Misiachna, Anna;
    • Kolcheva, Marharyta;
    • Andrys, Rudolf;
    • Handl, Jiri;
    • Capek, Jan;
    • Nyvltova, Pavlina;
    • Rousar, Tomas;
    • Prchal, Lukas;
    • Hepnarova, Vendula;
    • Hrabinova, Martina;
    • Muckova, Lubica;
    • Tosnerova, Daniela;
    • Karabanovich, Galina;
    • Finger, Vladimir;
    • Soukup, Ondrej;
    • Horak, Martin;
    • Korabecny, Jan
    Publication type:
    Article
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    Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies.

    Published in:
    International Journal of Molecular Sciences, 2021, v. 22, n. 15, p. 8308, doi. 10.3390/ijms22158308
    By:
    • Mamun, Abdullah Al;
    • Pidaný, Filip;
    • Hulcová, Daniela;
    • Maříková, Jana;
    • Kučera, Tomáš;
    • Schmidt, Monika;
    • Catapano, Maria Carmen;
    • Hrabinová, Martina;
    • Jun, Daniel;
    • Múčková, Lubica;
    • Kuneš, Jiří;
    • Janoušek, Jiří;
    • Andrýs, Rudolf;
    • Nováková, Lucie;
    • Peřinová, Rozálie;
    • Maafi, Negar;
    • Soukup, Ondřej;
    • Korábečný, Jan;
    • Cahlíková, Lucie
    Publication type:
    Article
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    Synthesis of New Biscoumarin Derivatives, In Vitro Cholinesterase Inhibition, Molecular Modelling and Antiproliferative Effect in A549 Human Lung Carcinoma Cells.

    Published in:
    International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3830, doi. 10.3390/ijms22083830
    By:
    • Hudáčová, Monika;
    • Hamuľaková, Slávka;
    • Konkoľová, Eva;
    • Jendželovský, Rastislav;
    • Vargová, Jana;
    • Ševc, Juraj;
    • Fedoročko, Peter;
    • Soukup, Ondrej;
    • Janočková, Jana;
    • Ihnatova, Veronika;
    • Kučera, Tomáš;
    • Bzonek, Petr;
    • Novakova, Nikola;
    • Jun, Daniel;
    • Junova, Lucie;
    • Korábečný, Jan;
    • Kuča, Kamil;
    • Kožurková, Mária
    Publication type:
    Article
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    Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510
    By:
    • Panek, Dawid;
    • Pasieka, Anna;
    • Jończyk, Jakub;
    • Gawlińska, Milena;
    • Zaręba, Paula;
    • Siwek, Agata;
    • Wolak, Małgorzata;
    • Mordyl, Barbara;
    • Głuch‐Lutwin, Monika;
    • Latacz, Gniewomir;
    • Brazzolotto, Xavier;
    • Chantegreil, Fabien;
    • Nachon, Florian;
    • Zdarova Karasova, Jana;
    • Pejchal, Jaroslav;
    • Mzik, Martin;
    • Sestak, Vit;
    • Prchal, Lukas;
    • Odvarkova, Jitka;
    • Soukup, Ondrej
    Publication type:
    Article
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    Gulf war syndrome - a syndrome or not?

    Published in:
    Toxin Reviews, 2015, v. 34, n. 1, p. 43, doi. 10.3109/15569543.2014.994131
    By:
    • Patocka, Jiri;
    • Honegr, Jan;
    • Soukup, Ondrej
    Publication type:
    Article
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    Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N -Methyl-d-Aspartate Receptor Antagonists.

    Published in:
    Biomolecules (2218-273X), 2021, v. 11, n. 1, p. 3, doi. 10.3390/biom11010003
    By:
    • Konecny, Jan;
    • Misiachna, Anna;
    • Hrabinova, Martina;
    • Pulkrabkova, Lenka;
    • Benkova, Marketa;
    • Prchal, Lukas;
    • Kucera, Tomas;
    • Kobrlova, Tereza;
    • Finger, Vladimir;
    • Kolcheva, Marharyta;
    • Kortus, Stepan;
    • Jun, Daniel;
    • Valko, Marian;
    • Horak, Martin;
    • Soukup, Ondrej;
    • Korabecny, Jan
    Publication type:
    Article
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    Multipotente Liganden mit kombinierter Cholinesterase- und Monoaminooxidase-Inhibition sowie Histamin-H<sub>3</sub>R-Antagonismus bei neurodegenerativen Erkrankungen.

    Published in:
    Angewandte Chemie, 2017, v. 129, n. 41, p. 12939, doi. 10.1002/ange.201706072
    By:
    • Bautista ‐ Aguilera, Óscar M.;
    • Hagenow, Stefanie;
    • Palomino ‐ Antolin, Alejandra;
    • Farré ‐ Alins, Víctor;
    • Ismaili, Lhassane;
    • Joffrin, Pierre ‐ Louis;
    • Jimeno, María L.;
    • Soukup, Ondřej;
    • Janočková, Jana;
    • Kalinowsky, Lena;
    • Proschak, Ewgenij;
    • Iriepa, Isabel;
    • Moraleda, Ignacio;
    • Schwed, Johannes S.;
    • Romero Martínez, Alejandro;
    • López ‐ Muñoz, Francisco;
    • Chioua, Mourad;
    • Egea, Javier;
    • Ramsay, Rona R.;
    • Marco ‐ Contelles, José
    Publication type:
    Article
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    Cover Image, Volume 40, Issue 5.

    Published in:
    Medicinal Research Reviews, 2020, v. 40, n. 5, p. ii, doi. 10.1002/med.21616
    By:
    • Juza, Radomir;
    • Vlcek, Premysl;
    • Mezeiova, Eva;
    • Musilek, Kamil;
    • Soukup, Ondrej;
    • Korabecny, Jan
    Publication type:
    Article