Works by Soto-Matos, A.

Results: 28

Population pharmacokinetic-pharmacodynamic analysis of neutropenia in cancer patients receiving PM00104 (Zalypsis(®)).
Published in:
2012
By:
- González-Sales M;
- Valenzuela B;
- Pérez-Ruixo C;
- Fernández Teruel C;
- Miguel-Lillo B;
- Soto-Matos A;
- Pérez-Ruixo JJ;
- González-Sales, Mario;
- Valenzuela, Belén;
- Pérez-Ruixo, Carlos;
- Fernández Teruel, Carlos;
- Miguel-Lillo, Bernardo;
- Soto-Matos, Arturo;
- Pérez-Ruixo, Juan Jose
Publication type:
journal article
Population pharmacokinetics meta-analysis of plitidepsin (Aplidin) in cancer subjects.
Published in:
2009
By:
- Nalda-Molina R;
- Valenzuela B;
- Ramon-Lopez A;
- Miguel-Lillo B;
- Soto-Matos A;
- Perez-Ruixo JJ;
- Nalda-Molina, Ricardo;
- Valenzuela, Belén;
- Ramon-Lopez, Amelia;
- Miguel-Lillo, Bernardo;
- Soto-Matos, Arturo;
- Perez-Ruixo, Juan Jose
Publication type:
journal article
Population pharmacokinetic meta-analysis of trabectedin (ET-743, Yondelis) in cancer patients.
Published in:
2007
By:
- Perez-Ruixo, Juan Jose;
- Zannikos, Peter;
- Hirankarn, Sarapee;
- Stuyckens, Kim;
- Ludwig, Elizabeth A.;
- Soto-Matos, Arturo;
- Lopez-Lazaro, Luis;
- Owen, Joel S.
Publication type:
journal article
Acute Myeloid Leukemia Unlikely Related to Trabectedin Treatment.
Published in:
Acta Haematologica, 2011, v. 126, n. 4, p. 238, doi. 10.1159/000330952
By:
- Cartoafa, Mirela;
- Kahatt, Carmen;
- Soto-Matos, Arturo;
- Roy, Elena;
- Lardelli, Pilar
Publication type:
Article
Mechanism-based Pharmacokinetic/Pharmacodynamic Meta-analysis of Trabectedin (ET-743, Yondelis) Induced Neutropenia.
Published in:
Clinical Pharmacology & Therapeutics, 2008, v. 83, n. 1, p. 130, doi. 10.1038/sj.clpt.6100259
By:
- Hing, J.;
- Perez-Ruixo, J. J.;
- Stuyckens, K.;
- Soto-Matos, A.;
- Lopez-Lazaro, L.;
- Zannikos, P.
Publication type:
Article
Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis.
Published in:
Marine Drugs, 2011, v. 9, n. 6, p. 1007, doi. 10.3390/md9061007
By:
- Soto-Matos, Arturo;
- Szyldergemajn, Sergio;
- Extremera, Sonia;
- Miguel-Lillo, Bernardo;
- Alfaro, Vicente;
- Coronado, Cinthya;
- Lardelli, Pilar;
- Roy, Elena;
- Corrado, Claudia Silvia;
- Kahatt, Carmen
Publication type:
Article
Population Pharmacokinetic-Pharmacodynamic Analysis of Neutropenia in Cancer Patients Receiving PM00104 (Zalypsis®).
Published in:
Clinical Pharmacokinetics, 2012, v. 51, n. 11, p. 751, doi. 10.1007/s40262-012-0011-z
By:
- Gonzàlez-Sales, Mario;
- Valenzuela, Bélen;
- Pérez-Ruixo, Carlos;
- Fernández Teruel, Carlos;
- Miguel-Lillo, Bernardo;
- Soto-Matos, Arturo;
- Pérez-Ruixo, Juan Jose
Publication type:
Article
First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours.
Published in:
British Journal of Cancer, 2012, v. 106, n. 8, p. 1379, doi. 10.1038/bjc.2012.99
By:
- Yap, T A;
- Cortes-Funes, H;
- Shaw, H;
- Rodriguez, R;
- Olmos, D;
- Lal, R;
- Fong, P C;
- Tan, D S;
- Harris, D;
- Capdevila, J;
- Coronado, C;
- Alfaro, V;
- Soto-Matos, A;
- Fernández-Teruel, C;
- Siguero, M;
- Tabernero, J M;
- Paz-Ares, L;
- de Bono, J S;
- López-Martin, J A
Publication type:
Article
First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors.
Published in:
Investigational New Drugs, 2019, v. 37, n. 4, p. 674, doi. 10.1007/s10637-018-0674-x
By:
- Elez, Elena;
- Gomez-Roca, Carlos;
- Soto Matos-Pita, Arturo;
- Argiles, Guillem;
- Valentin, Thibaud;
- Coronado, Cinthya;
- Iglesias, Jorge;
- Macarulla, Teresa;
- Betrian, Sarah;
- Fudio, Salvador;
- Zaragoza, Katrin;
- Tabernero, Josep;
- Delord, Jean-Pierre
Publication type:
Article
Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule.
Published in:
Investigational New Drugs, 2017, v. 35, n. 4, p. 471, doi. 10.1007/s10637-017-0427-2
By:
- Jimeno, Antonio;
- Sharma, Manish;
- Szyldergemajn, Sergio;
- Gore, Lia;
- Geary, David;
- Diamond, Jennifer;
- Fernandez Teruel, Carlos;
- Soto Matos-Pita, Arturo;
- Iglesias, Jorge;
- Cullell-Young, Martin;
- Ratain, Mark
Publication type:
Article
Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas.
Published in:
Investigational New Drugs, 2011, v. 29, n. 6, p. 1406, doi. 10.1007/s10637-010-9488-1
By:
- Salazar, Ramón;
- Plummer, Ruth;
- Oaknin, Ana;
- Robinson, Angela;
- Pardo, Beatriz;
- Soto-Matos, Arturo;
- Yovine, Alejandro;
- Szyldergemajn, Sergio;
- Calvert, Alan
Publication type:
Article
Population pharmacokinetics of kahalalide F in advanced cancer patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 2, p. 365, doi. 10.1007/s00280-015-2800-1
By:
- Miguel-Lillo, Bernardo;
- Valenzuela, Belén;
- Peris-Ribera, José;
- Soto-Matos, Arturo;
- Pérez-Ruixo, Juan
Publication type:
Article
Phase I study of weekly kahalalide F as prolonged infusion in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 1, p. 75, doi. 10.1007/s00280-013-2170-5
By:
- Salazar, R.;
- Cortés-Funes, H.;
- Casado, E.;
- Pardo, B.;
- López-Martín, A.;
- Cuadra, C.;
- Tabernero, J.;
- Coronado, C.;
- García, M.;
- Soto Matos-Pita, A.;
- Miguel-Lillo, B.;
- Cullell-Young, M.;
- Iglesias Dios, J.;
- Paz-Ares, L.
Publication type:
Article
A phase I pharmacokinetic study of PM00104 (Zalypsis((R))) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors.
Published in:
2013
By:
- Capdevila, J;
- Clive, S;
- Casado, E;
- Michie, C;
- Piera, A;
- Sicart, E;
- Carreras, M J;
- Coronado, C;
- Kahatt, C;
- Soto Matos-Pita, A;
- Fernandez Teruel, C;
- Siguero, M;
- Cullell-Young, M;
- Tabernero, J
Publication type:
Journal Article
A phase I pharmacokinetic study of PM00104 (Zalypsis) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 5, p. 1247, doi. 10.1007/s00280-013-2119-8
By:
- Capdevila, J.;
- Clive, S.;
- Casado, E.;
- Michie, C.;
- Piera, A.;
- Sicart, E.;
- Carreras, M.;
- Coronado, C.;
- Kahatt, C.;
- Soto Matos-Pita, A.;
- Fernandez Teruel, C.;
- Siguero, M.;
- Cullell-Young, M.;
- Tabernero, J.
Publication type:
Article
A phase I and pharmacokinetic study of elisidepsin (PM02734) in patients with advanced solid tumors.
Published in:
Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 5, p. 673, doi. 10.1007/s00280-012-1951-6
By:
- Salazar, R.;
- Jones, R.;
- Oaknin, A.;
- Crawford, D.;
- Cuadra, C.;
- Hopkins, C.;
- Gil, M.;
- Coronado, C.;
- Soto-Matos, A.;
- Cullell-Young, M.;
- Iglesias Dios, J.;
- Evans, T.
Publication type:
Article
A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin.
Published in:
Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1557, doi. 10.1007/s00280-012-1864-4
By:
- Grosso, Federica;
- D'Incalci, Maurizio;
- Cartoafa, Mirela;
- Nieto, Antonio;
- Fernández-Teruel, Carlos;
- Alfaro, Vicente;
- Lardelli, Pilar;
- Roy, Elena;
- Gómez, Javier;
- Kahatt, Carmen;
- Soto-Matos, Arturo;
- Judson, Ian
Publication type:
Article
Population pharmacokinetics of PM00104 (Zalypsis((R))) in cancer patients.
Published in:
2012
By:
- Pérez-Ruixo C;
- Valenzuela B;
- Fernández Teruel C;
- González-Sales M;
- Miguel-Lillo B;
- Soto-Matos A;
- Pérez-Ruixo JJ
Publication type:
Journal Article
Population pharmacokinetics of PM00104 (Zalypsis) in cancer patients.
Published in:
Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 15, doi. 10.1007/s00280-011-1644-6
By:
- Pérez-Ruixo, Carlos;
- Valenzuela, Belén;
- Fernández Teruel, Carlos;
- González-Sales, Mario;
- Miguel-Lillo, Bernardo;
- Soto-Matos, Arturo;
- Pérez-Ruixo, Juan
Publication type:
Article
Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.
Published in:
2011
By:
- Schöffski P;
- Dumez H;
- Ruijter R;
- Miguel-Lillo B;
- Soto-Matos A;
- Alfaro V;
- Giaccone G
Publication type:
Journal Article
Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1397, doi. 10.1007/s00280-011-1612-1
By:
- Schöffski, P.;
- Dumez, H.;
- Ruijter, R.;
- Miguel-Lillo, B.;
- Soto-Matos, A.;
- Alfaro, V.;
- Giaccone, G.
Publication type:
Article
Trabectedin has a low cardiac risk profile: a comprehensive cardiac safety analysis.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1223, doi. 10.1007/s00280-011-1614-z
By:
- Lebedinsky, Claudia;
- Gómez, Javier;
- Park, Youn;
- Nieto, Antonio;
- Soto-Matos, Arturo;
- Parekh, Trilok;
- Alfaro, Vicente;
- Roy, Elena;
- Lardelli, Pilar;
- Kahatt, Carmen
Publication type:
Article
Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease.
Published in:
Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1363, doi. 10.1007/s00280-011-1718-5
By:
- Thariat, Juliette;
- Etienne-Grimaldi, Marie-Christine;
- Launay-Vacher, Vincent;
- Soto-Matos, Arturo;
- Fernandez-Teruel, Carlos;
- Ghafari, Thomas;
- Marcy, Pierre-Yves;
- Milano, Gérard;
- Renée, Nicole;
- Gastaud, Lauris;
- Thyss, Antoine
Publication type:
Article
Population pharmacokinetics meta-analysis of plitidepsin (Aplidin<sup>®</sup>) in cancer subjects.
Published in:
Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 1, p. 97, doi. 10.1007/s00280-008-0841-4
By:
- Nalda-Molina, Ricardo;
- Valenzuela, Belén;
- Ramon-Lopez, Amelia;
- Miguel-Lillo, Bernardo;
- Soto-Matos, Arturo;
- Perez-Ruixo, Juan
Publication type:
Article
Semimechanistic pharmacokinetic/pharmacodynamic model for hepatoprotective effect of dexamethasone on transient transaminitis after trabectedin (ET-743) treatment.
Published in:
Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 1, p. 135, doi. 10.1007/s00280-007-0583-8
By:
- Fetterly, Gerald J.;
- Owen, Joel S.;
- Stuyckens, Kim;
- Passarell, Julie A.;
- Zannikos, Peter;
- Soto-Matos, Arturo;
- Izquierdo, Miguel Angel;
- Perez-Ruixo, Juan Jose
Publication type:
Article
Experience with Trabectedin in an Advanced Sarcoma Patient on Peritoneal Dialysis for End-Stage Renal Failure.
Published in:
Chemotherapy (0009-3157), 2014, v. 59, n. 6, p. 458, doi. 10.1159/000365071
By:
- Moe, Maung Maung Myat;
- Fernandez Teruel, Carlos;
- Soto-Matos, arturo
Publication type:
Article
Phase I and pharmacokinetic study of trabectedin 3-hour infusion every three weeks in patients with advanced cancer and alteration of hepatic function.
Published in:
Medical Oncology, 2012, v. 29, n. 3, p. 2240, doi. 10.1007/s12032-011-9979-8
By:
- Pardo, Beatriz;
- Salazar, Ramón;
- Ciruelos, Eva;
- Cortés-Funes, Hernán;
- García, Margarita;
- Majem, Margarita;
- Montes, Ana;
- Cuadra, Carmen;
- Soto-Matos, Arturo;
- Lebedinsky, Claudia;
- Alfaro, Vicente;
- Paz-Ares, Luis
Publication type:
Article
Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial.
Published in:
BMC Pharmacology & Toxicology, 2012, v. 13, p. 1, doi. 10.1186/2050-6511-13-20
By:
- García-Vega, Yanelda;
- García-García, Idrian;
- Collazo-Caballero, Sonia E.;
- Santely-Pravia, Egla E.;
- Cruz-Ramírez, Alieski;
- Tuero-Iglesias, Ángela D.;
- Alfonso-Alvarado, Cristian;
- Cabrera-Placeres, Mileidys;
- Castro-Basart, Nailet;
- Duncan-Roberts, Yaquelín;
- Carballo-Treto, Tania I.;
- Soto-Matos, Josanne;
- Izquierdo-Toledo, Yoandy;
- Vázquez-Blomquist, Dania;
- García-Iglesias, Elizeth;
- Bello-Rivero, Iraldo
Publication type:
Article