Works by Soto-Matos, A.

Results: 28

Population pharmacokinetics meta-analysis of plitidepsin (Aplidin) in cancer subjects.

Published in:

2009

By:

Nalda-Molina R;
Valenzuela B;
Ramon-Lopez A;
Miguel-Lillo B;
Soto-Matos A;
Perez-Ruixo JJ;
Nalda-Molina, Ricardo;
Valenzuela, Belén;
Ramon-Lopez, Amelia;
Miguel-Lillo, Bernardo;
Soto-Matos, Arturo;
Perez-Ruixo, Juan Jose

Publication type:

journal article

Population pharmacokinetic-pharmacodynamic analysis of neutropenia in cancer patients receiving PM00104 (Zalypsis(®)).

Published in:

2012

By:

González-Sales M;
Valenzuela B;
Pérez-Ruixo C;
Fernández Teruel C;
Miguel-Lillo B;
Soto-Matos A;
Pérez-Ruixo JJ;
González-Sales, Mario;
Valenzuela, Belén;
Pérez-Ruixo, Carlos;
Fernández Teruel, Carlos;
Miguel-Lillo, Bernardo;
Soto-Matos, Arturo;
Pérez-Ruixo, Juan Jose

Publication type:

journal article

First-in-man phase I trial of two schedules of the novel synthetic tetrahydroisoquinoline alkaloid PM00104 (Zalypsis) in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2012, v. 106, n. 8, p. 1379, doi. 10.1038/bjc.2012.99

By:

Yap, T A;
Cortes-Funes, H;
Shaw, H;
Rodriguez, R;
Olmos, D;
Lal, R;
Fong, P C;
Tan, D S;
Harris, D;
Capdevila, J;
Coronado, C;
Alfaro, V;
Soto-Matos, A;
Fernández-Teruel, C;
Siguero, M;
Tabernero, J M;
Paz-Ares, L;
de Bono, J S;
López-Martin, J A

Publication type:

Article

Phase I and pharmacokinetic study of trabectedin 3-hour infusion every three weeks in patients with advanced cancer and alteration of hepatic function.

Published in:

Medical Oncology, 2012, v. 29, n. 3, p. 2240, doi. 10.1007/s12032-011-9979-8

By:

Pardo, Beatriz;
Salazar, Ramón;
Ciruelos, Eva;
Cortés-Funes, Hernán;
García, Margarita;
Majem, Margarita;
Montes, Ana;
Cuadra, Carmen;
Soto-Matos, Arturo;
Lebedinsky, Claudia;
Alfaro, Vicente;
Paz-Ares, Luis

Publication type:

Article

Population pharmacokinetics of kahalalide F in advanced cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2015, v. 76, n. 2, p. 365, doi. 10.1007/s00280-015-2800-1

By:

Miguel-Lillo, Bernardo;
Valenzuela, Belén;
Peris-Ribera, José;
Soto-Matos, Arturo;
Pérez-Ruixo, Juan

Publication type:

Article

Phase I study of weekly kahalalide F as prolonged infusion in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 72, n. 1, p. 75, doi. 10.1007/s00280-013-2170-5

By:

Salazar, R.;
Cortés-Funes, H.;
Casado, E.;
Pardo, B.;
López-Martín, A.;
Cuadra, C.;
Tabernero, J.;
Coronado, C.;
García, M.;
Soto Matos-Pita, A.;
Miguel-Lillo, B.;
Cullell-Young, M.;
Iglesias Dios, J.;
Paz-Ares, L.

Publication type:

Article

A phase I pharmacokinetic study of PM00104 (Zalypsis((R))) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors.

Published in:

2013

By:

Capdevila, J;
Clive, S;
Casado, E;
Michie, C;
Piera, A;
Sicart, E;
Carreras, M J;
Coronado, C;
Kahatt, C;
Soto Matos-Pita, A;
Fernandez Teruel, C;
Siguero, M;
Cullell-Young, M;
Tabernero, J

Publication type:

Journal Article

A phase I pharmacokinetic study of PM00104 (Zalypsis) administered as a 24-h intravenous infusion every 3 weeks in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 5, p. 1247, doi. 10.1007/s00280-013-2119-8

By:

Capdevila, J.;
Clive, S.;
Casado, E.;
Michie, C.;
Piera, A.;
Sicart, E.;
Carreras, M.;
Coronado, C.;
Kahatt, C.;
Soto Matos-Pita, A.;
Fernandez Teruel, C.;
Siguero, M.;
Cullell-Young, M.;
Tabernero, J.

Publication type:

Article

A phase I and pharmacokinetic study of elisidepsin (PM02734) in patients with advanced solid tumors.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 70, n. 5, p. 673, doi. 10.1007/s00280-012-1951-6

By:

Salazar, R.;
Jones, R.;
Oaknin, A.;
Crawford, D.;
Cuadra, C.;
Hopkins, C.;
Gil, M.;
Coronado, C.;
Soto-Matos, A.;
Cullell-Young, M.;
Iglesias Dios, J.;
Evans, T.

Publication type:

Article

A comprehensive safety analysis confirms rhabdomyolysis as an uncommon adverse reaction in patients treated with trabectedin.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 6, p. 1557, doi. 10.1007/s00280-012-1864-4

By:

Grosso, Federica;
D'Incalci, Maurizio;
Cartoafa, Mirela;
Nieto, Antonio;
Fernández-Teruel, Carlos;
Alfaro, Vicente;
Lardelli, Pilar;
Roy, Elena;
Gómez, Javier;
Kahatt, Carmen;
Soto-Matos, Arturo;
Judson, Ian

Publication type:

Article

Population pharmacokinetics of PM00104 (Zalypsis((R))) in cancer patients.

Published in:

2012

By:

Pérez-Ruixo C;
Valenzuela B;
Fernández Teruel C;
González-Sales M;
Miguel-Lillo B;
Soto-Matos A;
Pérez-Ruixo JJ

Publication type:

Journal Article

Population pharmacokinetics of PM00104 (Zalypsis) in cancer patients.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 15, doi. 10.1007/s00280-011-1644-6

By:

Pérez-Ruixo, Carlos;
Valenzuela, Belén;
Fernández Teruel, Carlos;
González-Sales, Mario;
Miguel-Lillo, Bernardo;
Soto-Matos, Arturo;
Pérez-Ruixo, Juan

Publication type:

Article

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.

Published in:

2011

By:

Schöffski P;
Dumez H;
Ruijter R;
Miguel-Lillo B;
Soto-Matos A;
Alfaro V;
Giaccone G

Publication type:

Journal Article

Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 6, p. 1397, doi. 10.1007/s00280-011-1612-1

By:

Schöffski, P.;
Dumez, H.;
Ruijter, R.;
Miguel-Lillo, B.;
Soto-Matos, A.;
Alfaro, V.;
Giaccone, G.

Publication type:

Article

Trabectedin has a low cardiac risk profile: a comprehensive cardiac safety analysis.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1223, doi. 10.1007/s00280-011-1614-z

By:

Lebedinsky, Claudia;
Gómez, Javier;
Park, Youn;
Nieto, Antonio;
Soto-Matos, Arturo;
Parekh, Trilok;
Alfaro, Vicente;
Roy, Elena;
Lardelli, Pilar;
Kahatt, Carmen

Publication type:

Article

Pharmacokinetics of trabectedin on hemodialysis: an application for the management of cancer patients with end-stage renal disease.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 68, n. 5, p. 1363, doi. 10.1007/s00280-011-1718-5

By:

Thariat, Juliette;
Etienne-Grimaldi, Marie-Christine;
Launay-Vacher, Vincent;
Soto-Matos, Arturo;
Fernandez-Teruel, Carlos;
Ghafari, Thomas;
Marcy, Pierre-Yves;
Milano, Gérard;
Renée, Nicole;
Gastaud, Lauris;
Thyss, Antoine

Publication type:

Article

Population pharmacokinetics meta-analysis of plitidepsin (Aplidin<sup>®</sup>) in cancer subjects.

Published in:

Cancer Chemotherapy & Pharmacology, 2009, v. 64, n. 1, p. 97, doi. 10.1007/s00280-008-0841-4

By:

Nalda-Molina, Ricardo;
Valenzuela, Belén;
Ramon-Lopez, Amelia;
Miguel-Lillo, Bernardo;
Soto-Matos, Arturo;
Perez-Ruixo, Juan

Publication type:

Article

Semimechanistic pharmacokinetic/pharmacodynamic model for hepatoprotective effect of dexamethasone on transient transaminitis after trabectedin (ET-743) treatment.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 62, n. 1, p. 135, doi. 10.1007/s00280-007-0583-8

By:

Fetterly, Gerald J.;
Owen, Joel S.;
Stuyckens, Kim;
Passarell, Julie A.;
Zannikos, Peter;
Soto-Matos, Arturo;
Izquierdo, Miguel Angel;
Perez-Ruixo, Juan Jose

Publication type:

Article

Pharmacokinetic and pharmacodynamic characterization of a new formulation containing synergistic proportions of interferons alpha-2b and gamma (HeberPAG®) in patients with mycosis fungoides: an open-label trial.

Published in:

BMC Pharmacology & Toxicology, 2012, v. 13, p. 1, doi. 10.1186/2050-6511-13-20

By:

García-Vega, Yanelda;
García-García, Idrian;
Collazo-Caballero, Sonia E.;
Santely-Pravia, Egla E.;
Cruz-Ramírez, Alieski;
Tuero-Iglesias, Ángela D.;
Alfonso-Alvarado, Cristian;
Cabrera-Placeres, Mileidys;
Castro-Basart, Nailet;
Duncan-Roberts, Yaquelín;
Carballo-Treto, Tania I.;
Soto-Matos, Josanne;
Izquierdo-Toledo, Yoandy;
Vázquez-Blomquist, Dania;
García-Iglesias, Elizeth;
Bello-Rivero, Iraldo

Publication type:

Article

Population Pharmacokinetic-Pharmacodynamic Analysis of Neutropenia in Cancer Patients Receiving PM00104 (Zalypsis®).

Published in:

Clinical Pharmacokinetics, 2012, v. 51, n. 11, p. 751, doi. 10.1007/s40262-012-0011-z

By:

Gonzàlez-Sales, Mario;
Valenzuela, Bélen;
Pérez-Ruixo, Carlos;
Fernández Teruel, Carlos;
Miguel-Lillo, Bernardo;
Soto-Matos, Arturo;
Pérez-Ruixo, Juan Jose

Publication type:

Article

Population pharmacokinetic meta-analysis of trabectedin (ET-743, Yondelis) in cancer patients.

Published in:

2007

By:

Perez-Ruixo, Juan Jose;
Zannikos, Peter;
Hirankarn, Sarapee;
Stuyckens, Kim;
Ludwig, Elizabeth A.;
Soto-Matos, Arturo;
Lopez-Lazaro, Luis;
Owen, Joel S.

Publication type:

journal article

First-in-human phase I study of the microtubule inhibitor plocabulin in patients with advanced solid tumors.

Published in:

Investigational New Drugs, 2019, v. 37, n. 4, p. 674, doi. 10.1007/s10637-018-0674-x

By:

Elez, Elena;
Gomez-Roca, Carlos;
Soto Matos-Pita, Arturo;
Argiles, Guillem;
Valentin, Thibaud;
Coronado, Cinthya;
Iglesias, Jorge;
Macarulla, Teresa;
Betrian, Sarah;
Fudio, Salvador;
Zaragoza, Katrin;
Tabernero, Josep;
Delord, Jean-Pierre

Publication type:

Article

Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule.

Published in:

Investigational New Drugs, 2017, v. 35, n. 4, p. 471, doi. 10.1007/s10637-017-0427-2

By:

Jimeno, Antonio;
Sharma, Manish;
Szyldergemajn, Sergio;
Gore, Lia;
Geary, David;
Diamond, Jennifer;
Fernandez Teruel, Carlos;
Soto Matos-Pita, Arturo;
Iglesias, Jorge;
Cullell-Young, Martin;
Ratain, Mark

Publication type:

Article

Phase I study of weekly plitidepsin as 1-hour infusion combined with carboplatin in patients with advanced solid tumors or lymphomas.

Published in:

Investigational New Drugs, 2011, v. 29, n. 6, p. 1406, doi. 10.1007/s10637-010-9488-1

By:

Salazar, Ramón;
Plummer, Ruth;
Oaknin, Ana;
Robinson, Angela;
Pardo, Beatriz;
Soto-Matos, Arturo;
Yovine, Alejandro;
Szyldergemajn, Sergio;
Calvert, Alan

Publication type:

Article

Acute Myeloid Leukemia Unlikely Related to Trabectedin Treatment.

Published in:

Acta Haematologica, 2011, v. 126, n. 4, p. 238, doi. 10.1159/000330952

By:

Cartoafa, Mirela;
Kahatt, Carmen;
Soto-Matos, Arturo;
Roy, Elena;
Lardelli, Pilar

Publication type:

Article

Mechanism-based Pharmacokinetic/Pharmacodynamic Meta-analysis of Trabectedin (ET-743, Yondelis) Induced Neutropenia.

Published in:

Clinical Pharmacology & Therapeutics, 2008, v. 83, n. 1, p. 130, doi. 10.1038/sj.clpt.6100259

By:

Hing, J.;
Perez-Ruixo, J. J.;
Stuyckens, K.;
Soto-Matos, A.;
Lopez-Lazaro, L.;
Zannikos, P.

Publication type:

Article

Experience with Trabectedin in an Advanced Sarcoma Patient on Peritoneal Dialysis for End-Stage Renal Failure.

Published in:

Chemotherapy (0009-3157), 2014, v. 59, n. 6, p. 458, doi. 10.1159/000365071

By:

Moe, Maung Maung Myat;
Fernandez Teruel, Carlos;
Soto-Matos, arturo

Publication type:

Article

Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis.

Published in:

Marine Drugs, 2011, v. 9, n. 6, p. 1007, doi. 10.3390/md9061007

By:

Soto-Matos, Arturo;
Szyldergemajn, Sergio;
Extremera, Sonia;
Miguel-Lillo, Bernardo;
Alfaro, Vicente;
Coronado, Cinthya;
Lardelli, Pilar;
Roy, Elena;
Corrado, Claudia Silvia;
Kahatt, Carmen

Publication type:

Article