Found: 14

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  • Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.

    Published in:
    2009
    By:
    • Sos, Martin L.;
    • Michel, Kathrin;
    • Zander, Thomas;
    • Weiss, Jonathan;
    • Frommolt, Peter;
    • Peifer, Martin;
    • Danan Li;
    • Ullrich, Roland;
    • Koker, Mirjam;
    • Fischer, Florian;
    • Shimamura, Takeshi;
    • Rauh, Daniel;
    • Mermel, Craig;
    • Fischer, Stefanie;
    • Stückrath, Isabel;
    • Heynck, Stefanie;
    • Beroukhim, Rameen;
    • Lin, William;
    • Winckler, Wendy;
    • Shah, Kinjal
    Publication type:
    journal article

  • Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22336-4
    By:
    • Bebber, Christina M.;
    • Thomas, Emily S.;
    • Stroh, Jenny;
    • Chen, Zhiyi;
    • Androulidaki, Ariadne;
    • Schmitt, Anna;
    • Höhne, Michaela N.;
    • Stüker, Lukas;
    • de Pádua Alves, Cleidson;
    • Khonsari, Armin;
    • Dammert, Marcel A.;
    • Parmaksiz, Fatma;
    • Tumbrink, Hannah L.;
    • Beleggia, Filippo;
    • Sos, Martin L.;
    • Riemer, Jan;
    • George, Julie;
    • Brodesser, Susanne;
    • Thomas, Roman K.;
    • Reinhardt, H. Christian
    Publication type:
    Article

  • Ferroptosis response segregates small cell lung cancer (SCLC) neuroendocrine subtypes.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22336-4
    By:
    • Bebber, Christina M.;
    • Thomas, Emily S.;
    • Stroh, Jenny;
    • Chen, Zhiyi;
    • Androulidaki, Ariadne;
    • Schmitt, Anna;
    • Höhne, Michaela N.;
    • Stüker, Lukas;
    • de Pádua Alves, Cleidson;
    • Khonsari, Armin;
    • Dammert, Marcel A.;
    • Parmaksiz, Fatma;
    • Tumbrink, Hannah L.;
    • Beleggia, Filippo;
    • Sos, Martin L.;
    • Riemer, Jan;
    • George, Julie;
    • Brodesser, Susanne;
    • Thomas, Roman K.;
    • Christian Reinhardt, H.
    Publication type:
    Article

  • A crucial requirement for Hedgehog signaling in small cell lung cancer.

    Published in:
    Nature Medicine, 2011, v. 17, n. 11, p. 1504, doi. 10.1038/nm.2473
    By:
    • Park, Kwon-Sik;
    • Martelotto, Luciano G;
    • Peifer, Martin;
    • Sos, Martin L;
    • Karnezis, Anthony N;
    • Mahjoub, Moe R;
    • Bernard, Katie;
    • Conklin, Jamie F;
    • Szczepny, Anette;
    • Yuan, Jing;
    • Guo, Ribo;
    • Ospina, Beatrice;
    • Falzon, Jeanette;
    • Bennett, Samara;
    • Brown, Tracey J;
    • Markovic, Ana;
    • Devereux, Wendy L;
    • Ocasio, Cory A;
    • Chen, James K;
    • Stearns, Tim
    Publication type:
    Article

  • Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer.

    Published in:
    Nature Genetics, 2012, v. 44, n. 10, p. 1104, doi. 10.1038/ng.2396
    By:
    • Peifer, Martin;
    • Fernández-Cuesta, Lynnette;
    • Sos, Martin L;
    • George, Julie;
    • Seidel, Danila;
    • Kasper, Lawryn H;
    • Plenker, Dennis;
    • Leenders, Frauke;
    • Sun, Ruping;
    • Zander, Thomas;
    • Menon, Roopika;
    • Koker, Mirjam;
    • Dahmen, Ilona;
    • Müller, Christian;
    • Di Cerbo, Vincenzo;
    • Schildhaus, Hans-Ulrich;
    • Altmüller, Janine;
    • Baessmann, Ingelore;
    • Becker, Christian;
    • de Wilde, Bram
    Publication type:
    Article

  • Analysis of Compound Synergy in High-Throughput Cellular Screens by Population-Based Lifetime Modeling.

    Published in:
    PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008919
    By:
    • Peifer, Martin;
    • Weiss, Jonathan;
    • Sos, Martin L.;
    • Koker, Mirjam;
    • Heynck, Stefanie;
    • Netzer, Christian;
    • Fischer, Stefanie;
    • Rode, Haridas;
    • Rauh, Daniel;
    • Rahnenführer, Jörg;
    • Thomas, Roman K.
    Publication type:
    Article

  • Early Detection of Erlotinib Treatment Response in NSCLC by 3'-Deoxy-3'-[<sup>18</sup>F]-Fluoro-L-Thymidine ([<sup>18</sup>F]FLT) Positron Emission Tomography (PET).

    Published in:
    PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0003908
    By:
    • Ullrich, Roland T.;
    • Zander, Thomas;
    • Neumaier, Bernd;
    • Koker, Mirjam;
    • Shimamura, Takeshi;
    • Waerzeggers, Yannic;
    • Borgman, Christa L.;
    • Tawadros, Samir;
    • Hongfeng Li;
    • Sos, Martin L.;
    • Backes, Heiko;
    • Shapiro, Geoffrey I.;
    • Wolf, Jürgen;
    • Jacobs, Andreas H.;
    • Thomas, Roman K.;
    • Winkeler, Alexandra
    Publication type:
    Article

  • MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer.

    Published in:
    Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11371-x
    By:
    • Dammert, Marcel A.;
    • Monhasery, Niloufar;
    • Tumbrink, Hannah L.;
    • Marx, Annika;
    • Lorenz, Carina;
    • Sos, Martin L.;
    • Brägelmann, Johannes;
    • Ozretić, Luka;
    • Wolf, Elmar;
    • Poirier, John T.;
    • Sen, Triparna;
    • Byers, Lauren A.;
    • Thomas, Roman K.;
    • Böhm, Stefanie;
    • Klein, Sebastian;
    • Castiglione, Roberta;
    • Reinhardt, H. Christian;
    • Olsen, Rachelle R.;
    • Whitney, Christopher P.;
    • Chalishazar, Milind D.
    Publication type:
    Article

  • AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.

    Published in:
    EMBO Journal, 2012, v. 31, n. 20, p. 3961, doi. 10.1038/emboj.2012.236
    By:
    • Höpker, Katja;
    • Hagmann, Henning;
    • Khurshid, Safiya;
    • Chen, Shuhua;
    • Hasskamp, Pia;
    • Seeger-Nukpezah, Tamina;
    • Schilberg, Katharina;
    • Heukamp, Lukas;
    • Lamkemeyer, Tobias;
    • Sos, Martin L;
    • Thomas, Roman K;
    • Lowery, Drew;
    • Roels, Frederik;
    • Fischer, Matthias;
    • Liebau, Max C;
    • Resch, Ulrike;
    • Kisner, Tülay;
    • Röther, Fabian;
    • Bartram, Malte P;
    • Müller, Roman Ulrich
    Publication type:
    Article

  • Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

    Published in:
    Nature, 2009, v. 462, n. 7269, p. 108, doi. 10.1038/nature08460
    By:
    • Barbie, David A.;
    • Tamayo, Pablo;
    • Boehm, Jesse S.;
    • Kim, So Young;
    • Moody, Susan E.;
    • Dunn, Ian F.;
    • Schinzel, Anna C.;
    • Sandy, Peter;
    • Meylan, Etienne;
    • Scholl, Claudia;
    • Fröhling, Stefan;
    • Chan, Edmond M.;
    • Sos, Martin L.;
    • Michel, Kathrin;
    • Mermel, Craig;
    • Silver, Serena J.;
    • Weir, Barbara A.;
    • Reiling, Jan H.;
    • Sheng, Qing;
    • Gupta, Piyush B.
    Publication type:
    Article

  • Sorafenib and everolimus in patients with advanced solid tumors and KRAS‐mutated NSCLC: A phase I trial with early pharmacodynamic FDG‐PET assessment.

    Published in:
    Cancer Medicine, 2020, v. 9, n. 14, p. 4991, doi. 10.1002/cam4.3131
    By:
    • Nogova, Lucia;
    • Mattonet, Christian;
    • Scheffler, Matthias;
    • Taubert, Max;
    • Gardizi, Masyar;
    • Sos, Martin L.;
    • Michels, Sebastian;
    • Fischer, Rieke N.;
    • Limburg, Meike;
    • Abdulla, Diana S.Y.;
    • Persigehl, Thorsten;
    • Kobe, Carsten;
    • Merkelbach‐Bruse, Sabine;
    • Franklin, Jeremy;
    • Backes, Heiko;
    • Schnell, Roland;
    • Behringer, Dirk;
    • Kaminsky, Britta;
    • Eichstaedt, Martina;
    • Stelzer, Christoph
    Publication type:
    Article

  • Optimization of Dosing for EGFR-Mutant Non-Small Cell Lung Cancer with Evolutionary Cancer Modeling.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 90, p. 1, doi. 10.1126/scitranslmed.3002356
    By:
    • Chmielecki, Juliann;
    • Jasmine Foo;
    • Oxnard, Geoffrey R.;
    • Hutchinson, Katherine;
    • Ohashi, Kadoaki;
    • Somwar, Romel;
    • Lu Wang;
    • Amato, Katherine R.;
    • Arcila, Maria;
    • Sos, Martin L.;
    • Socci, Nicholas D.;
    • Viale, Agnes;
    • de Stanchina, Elisa;
    • Ginsberg, Michelle S.;
    • Thomas, Roman K.;
    • Kris, Mark G.;
    • Inoue, Akira;
    • Ladanyi, Marc;
    • Miller, Vincent A.;
    • Michor, Franziska
    Publication type:
    Article

  • Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer.

    Published in:
    Science Translational Medicine, 2010, v. 2, n. 62, p. 1, doi. 10.1126/scitranslmed.3001451
    By:
    • Weiss, Jonathan;
    • Sos, Martin L.;
    • Seidel, Danila;
    • Peifer, Martin;
    • Zander, Thomas;
    • Heuckmann, Johannes M.;
    • Ullrich, Roland T.;
    • Menon, Roopika;
    • Maier, Sebastian;
    • Soltermann, Alex;
    • Moch, Holger;
    • Wagener, Patrick;
    • Fischer, Florian;
    • Heynck, Stefanie;
    • Koker, Mirjam;
    • Schöttle, Jakob;
    • Leenders, Frauke;
    • Gabler, Franziska;
    • Dabow, Ines;
    • Querings, Silvia
    Publication type:
    Article

  • K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.

    Published in:
    Nature, 2013, v. 503, n. 7477, p. 548, doi. 10.1038/nature12796
    By:
    • Ostrem, Jonathan M.;
    • Peters, Ulf;
    • Sos, Martin L.;
    • Wells, James A.;
    • Shokat, Kevan M.
    Publication type:
    Article