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  • CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

    Published in:
    Nature Communications, 2017, v. 8, n. 2, p. 14432, doi. 10.1038/ncomms14432
    By:
    • Xu, Hong;
    • Di Antonio, Marco;
    • McKinney, Steven;
    • Mathew, Veena;
    • Ho, Brandon;
    • O'Neil, Nigel J.;
    • Santos, Nancy Dos;
    • Silvester, Jennifer;
    • Wei, Vivien;
    • Garcia, Jessica;
    • Kabeer, Farhia;
    • Lai, Daniel;
    • Soriano, Priscilla;
    • Banáth, Judit;
    • Chiu, Derek S.;
    • Yap, Damian;
    • Le, Daniel D.;
    • Ye, Frank B.;
    • Zhang, Anni;
    • Thu, Kelsie
    Publication type:
    Article