Works by Sorg, Joseph A

Results: 23

Bile acid-independent protection against Clostridioides difficile infection.

Published in:

PLoS Pathogens, 2021, v. 17, n. 10, p. 1, doi. 10.1371/journal.ppat.1010015

By:

Aguirre, Andrea Martinez;
Yalcinkaya, Nazli;
Wu, Qinglong;
Swennes, Alton;
Tessier, Mary Elizabeth;
Roberts, Paul;
Miyajima, Fabio;
Savidge, Tor;
Sorg, Joseph A.

Publication type:

Article

The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation.

Published in:

PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009516

By:

Nerber, Hailee N.;
Sorg, Joseph A.

Publication type:

Article

Gut associated metabolites and their roles in Clostridioides difficile pathogenesis.

Published in:

Gut Microbes, 2022, v. 14, n. 1, p. 1, doi. 10.1080/19490976.2022.2094672

By:

Aguirre, Andrea Martinez;
Sorg, Joseph A.

Publication type:

Article

Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation.

Published in:

Gut Microbes, 2021, v. 13, n. 1, p. 1, doi. 10.1080/19490976.2020.1795388

By:

Engevik, Melinda A.;
Danhof, Heather A.;
Shrestha, Ritu;
Chang-Graham, Alexandra L.;
Hyser, Joseph M.;
Haag, Anthony M.;
Mohammad, Mahmoud A.;
Britton, Robert A.;
Versalovic, James;
Sorg, Joseph A.;
Spinler, Jennifer K.

Publication type:

Article

The requirement for co-germinants during C. difficile spore germination is influenced by mutations in yabG and cspA.

Published in:

PLoS Pathogens, 2019, v. 15, n. 4, p. 1, doi. 10.1371/journal.ppat.1007681

By:

Shrestha, Ritu;
Cochran, Alicia M.;
Sorg, Joseph A.

Publication type:

Article

Substrate recognition of type III secretion machines –testing the RNA signal hypothesis.

Published in:

Cellular Microbiology, 2005, v. 7, n. 9, p. 1217, doi. 10.1111/j.1462-5822.2005.00563.x

By:

Sorg, Joseph A.;
Miller, Nathan C.;
Schneewind, Olaf

Publication type:

Article

Regulatory transcription factors of Clostridioides difficile pathogenesis with a focus on toxin regulation.

Published in:

Critical Reviews in Microbiology, 2023, v. 49, n. 3, p. 334, doi. 10.1080/1040841X.2022.2054307

By:

Chandra, Harish;
Sorg, Joseph A.;
Hassett, Daniel J;
Sun, Xingmin

Publication type:

Article

Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination.

Published in:

PLoS Pathogens, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.ppat.1005239

By:

Fimlaid, Kelly A.;
Jensen, Owen;
Donnelly, M. Lauren;
Francis, Michael B.;
Sorg, Joseph A.;
Shen, Aimee

Publication type:

Article

Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

Published in:

PLoS Pathogens, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.ppat.1003356

By:

Francis, Michael B.;
Allen, Charlotte A.;
Shrestha, Ritu;
Sorg, Joseph A.

Publication type:

Article

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation.

Published in:

NPJ Biofilms & Microbiomes, 2022, v. 8, n. 1, p. 1, doi. 10.1038/s41522-022-00358-0

By:

Aguirre, Andrea Martinez;
Adegbite, Adegoke Oyeleye;
Sorg, Joseph A.

Publication type:

Article

Role of the global regulator Rex in control of NAD+‐regeneration in Clostridioides (Clostridium) difficile.

Published in:

Molecular Microbiology, 2019, v. 111, n. 6, p. 1671, doi. 10.1111/mmi.14245

By:

Bouillaut, Laurent;
Daou, Nadine;
Sonenshein, Abraham L.;
Dubois, Thomas;
Monot, Marc;
Dupuy, Bruno;
Francis, Michael B.;
Sorg, Joseph A.

Publication type:

Article

Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA.

Published in:

Molecular Microbiology, 2008, v. 70, n. 5, p. 1210, doi. 10.1111/j.1365-2958.2008.06474.x

By:

Blaylock, Bill;
Sorg, Joseph A.;
Schneewind, Olaf

Publication type:

Article

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.

Published in:

PLoS Pathogens, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.ppat.1012507

By:

Nerber, Hailee N.;
Baloh, Marko;
Brehm, Joshua N.;
Sorg, Joseph A.

Publication type:

Article

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

Published in:

PLoS Pathogens, 2023, v. 19, n. 11, p. 1, doi. 10.1371/journal.ppat.1011741

By:

Marini, Eleonora;
Olivença, Carmen;
Ramalhete, Sara;
Aguirre, Andrea Martinez;
Ingle, Patrick;
Melo, Manuel N.;
Antunes, Wilson;
Minton, Nigel P.;
Hernandez, Guillem;
Cordeiro, Tiago N.;
Sorg, Joseph A.;
Serrano, Mónica;
Henriques, Adriano O.

Publication type:

Article

Editorial: Alternative Therapeutic Approaches For Multidrug Resistant Clostridium difficile.

Published in:

2019

By:

Janvilisri, Tavan;
Sorg, Joseph A.;
Scaria, Joy;
Sadowsky, Michael J.

Publication type:

Editorial

Conservation of the "Outside-in" Germination Pathway in Paraclostridium bifermentans.

Published in:

Frontiers in Microbiology, 2018, p. N.PAG, doi. 10.3389/fmicb.2018.02487

By:

Bhattacharjee, Disha;
Sorg, Joseph A.

Publication type:

Article

Muricholic Acids Inhibit Clostridium difficile Spore Germination and Growth.

Published in:

PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073653

By:

Francis, Michael B.;
Allen, Charlotte A.;
Sorg, Joseph A.

Publication type:

Article

Metabolism of Bile Salts in Mice Influences Spore Germination in Clostridium difficile.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008740

By:

Giel, Jennifer L.;
Sorg, Joseph A.;
Sonenshein, Abraham L.;
Jun Zhu

Publication type:

Article

Regulation of peroxisome proliferator-activated receptor-β/δ by the APC/β-CATENIN pathway and nonsteroidal antiinflammatory drugs.

Published in:

Molecular Carcinogenesis, 2009, v. 48, n. 10, p. 942, doi. 10.1002/mc.20546

By:

Foreman, Jennifer E.;
Sorg, Joseph M.;
McGinnis, Kathleen S.;
Rigas, Basil;
Williams, Jennie L.;
Clapper, Margie L.;
Gonzalez, Frank J.;
Peters, Jeffrey M.

Publication type:

Article

Correction to: Protease-stable DARPins as promising oral therapeutics.

Published in:

2022

By:

Simeon, Rudo A;
Zeng, Yu;
Chonira, Vikas;
Aguirre, Andrea Martinez;
Lasagna, Mauricio;
Baloh, Marko;
Sorg, Joseph A;
Tommos, Cecilia;
Chen, Zhilei

Publication type:

Correction Notice

Protease-stable DARPins as promising oral therapeutics.

Published in:

PEDS: Protein Engineering, Design & Selection, 2021, v. 34, p. 1, doi. 10.1093/protein/gzab028

By:

Simeon, Rudo A;
Zeng, Yu;
Chonira, Vikas;
Aguirre, Andrea Martinez;
Lasagna, Mauricio;
Baloh, Marko;
Sorg, Joseph A;
Tommos, Cecilia;
Chen, Zhilei

Publication type:

Article

The Impact of YabG Mutations on Clostridioides difficile Spore Germination and Processing of Spore Substrates.

Published in:

Molecular Microbiology, 2024, v. 122, n. 4, p. 534, doi. 10.1111/mmi.15316

By:

Osborne, Morgan S.;
Brehm, Joshua N.;
Olivença, Carmen;
Cochran, Alicia M.;
Serrano, Mónica;
Henriques, Adriano O.;
Sorg, Joseph A.

Publication type:

Article

Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile.

Published in:

Molecular Microbiology, 2024, v. 122, n. 2, p. 213, doi. 10.1111/mmi.15291

By:

Martins, Diogo;
Nerber, Hailee N.;
Roughton, Charlotte G.;
Fasquelle, Amaury;
Barwinska‐Sendra, Anna;
Vollmer, Daniela;
Gray, Joe;
Vollmer, Waldemar;
Sorg, Joseph A.;
Salgado, Paula S.;
Henriques, Adriano O.;
Serrano, Mónica

Publication type:

Article

Works by Sorg, Joseph A

Bile acid-independent protection against Clostridioides difficile infection.

The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation.

Gut associated metabolites and their roles in Clostridioides difficile pathogenesis.

Reuterin disrupts Clostridioides difficile metabolism and pathogenicity through reactive oxygen species generation.

The requirement for co-germinants during C. difficile spore germination is influenced by mutations in yabG and cspA.

Substrate recognition of type III secretion machines –testing the RNA signal hypothesis.

Regulatory transcription factors of Clostridioides difficile pathogenesis with a focus on toxin regulation.

Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination.

Bile Acid Recognition by the <i>Clostridium difficile</i> Germinant Receptor, CspC, Is Important for Establishing Infection

Clostridioides difficile bile salt hydrolase activity has substrate specificity and affects biofilm formation.

Role of the global regulator Rex in control of NAD<sup>+</sup>‐regeneration in Clostridioides (Clostridium) difficile.

Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA.

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner.

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.

Editorial: Alternative Therapeutic Approaches For Multidrug Resistant Clostridium difficile.

Conservation of the "Outside-in" Germination Pathway in Paraclostridium bifermentans.

Muricholic Acids Inhibit <i>Clostridium difficile</i> Spore Germination and Growth.

Metabolism of Bile Salts in Mice Influences Spore Germination in Clostridium difficile.

Regulation of peroxisome proliferator-activated receptor-β/δ by the APC/β-CATENIN pathway and nonsteroidal antiinflammatory drugs.

Correction to: Protease-stable DARPins as promising oral therapeutics.

Protease-stable DARPins as promising oral therapeutics.

The Impact of YabG Mutations on Clostridioides difficile Spore Germination and Processing of Spore Substrates.

Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile.