Works by Soremekun, Opeyemi

Results: 36

Sequence-Based Mechanistic Resolution of Amino Acid Replacement and Impact on the Activities of Peptide-Based Derivatives Targeting CXCR4 for the Treatment of Waldenström's Macroglobulinemia.

Published in:

Journal of Computational Biophysics & Chemistry, 2024, v. 23, n. 2, p. 207, doi. 10.1142/S273741652350059X

By:

Elamin, Ghazi;
Soremekun, Opeyemi S.;
Sayed, Shaban R. M.;
Sidhom, Peter A.;
Ibrahim, Mahmoud A. A.;
Ahmed, Muhammad Naeem;
Soliman, Mahmoud E. S.

Publication type:

Article

Mendelian randomization study highlights the role of hematological traits on Type-2 diabetes mellitus in African ancestry individuals.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1436972

By:

Soremekun, Chisom;
Jjingo, Daudi;
Kateete, David;
Nash, Oyekanmi;
Nitsch, Dorothea;
Nyirenda, Moffat;
Gill, Dipender;
Zeggini, Eleftheria;
Grallert, Harald;
Peters, Annette;
Chikowore, Tinashe;
Batini, Chiara;
Soremekun, Opeyemi;
Fatumo, Segun

Publication type:

Article

Mutational analysis of p53 gene in cervical cancer and useful polymorphic variants in exons 3 and 4.

Published in:

Egyptian Journal of Medical Human Genetics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s43042-021-00144-1

By:

Gbadegesin, Michael A.;
Omotoso, Olabode E.;
Oluwasola, Timothy A. O.;
Okolo, Clement A.;
Soremekun, Opeyemi;
Ogun, Gabriel O.;
Oluwasola, Abideen O.;
Odunola, Oyeronke A.

Publication type:

Article

Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations.

Published in:

PLoS ONE, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pone.0280344

By:

Soremekun, Chisom;
Machipisa, Tafadzwa;
Soremekun, Opeyemi;
Pirie, Fraser;
Oyekanmi, Nashiru;
Motala, Ayesha A.;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function.

Published in:

BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09601-0

By:

Kintu, Christopher;
Soremekun, Opeyemi;
Machipisa, Tafadzwa;
Mayanja, Richard;
Kalyesubula, Robert;
Bagaya, Bernard S.;
Jjingo, Daudi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

A Mendelian randomization study of genetic liability to post-traumatic stress disorder and risk of ischemic stroke.

Published in:

Translational Psychiatry, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41398-023-02542-y

By:

Soremekun, Opeyemi;
Musanabaganwa, Clarisse;
Uwineza, Annette;
Ardissino, Maddalena;
Rajasundaram, Skanda;
Wani, Agaz H.;
Jansen, Stefan;
Mutabaruka, Jean;
Rutembesa, Eugene;
Soremekun, Chisom;
Cheickna, Cisse;
Wele, Mamadou;
Mugisha, Joseph;
Nash, Oyekanmi;
Kinyanda, Eugene;
Nitsch, Dorothea;
Fornage, Myriam;
Chikowore, Tinashe;
Gill, Dipender;
Wildman, Derek E.

Publication type:

Article

Genetics and Genomics in Health and Disease: A Focus on African Populations.

Published in:

Annals of Human Genetics, 2025, v. 89, n. 4, p. 133, doi. 10.1111/ahg.12603

By:

Chikowore, Tinashe;
Soremekun, Opeyemi;
Chilunga, Felix P.

Publication type:

Article

Causal effect of severe and non‐severe malaria on dyslipidemia in African Ancestry individuals: A Mendelian randomization study.

Published in:

Annals of Human Genetics, 2025, v. 89, n. 4, p. 178, doi. 10.1111/ahg.12555

By:

Traore, Mariam;
Sangare, Harouna;
Diabate, Oudou;
Diawara, Abdoulaye;
Cissé, Cheickna;
Nashiru, Oyekanmi;
Li, Jian;
Shaffer, Jeffrey;
Wélé, Mamadou;
Doumbia, Seydou;
Chikowore, Tinashe;
Soremekun, Opeyemi;
Fatumo, Segun

Publication type:

Article

Exploring the ring potential of 2,4-diaminopyrimidine derivatives towards the identification of novel caspase-1 inhibitors in Alzheimer's disease therapy.

Published in:

Journal of Molecular Modeling, 2020, v. 26, n. 4, p. 1, doi. 10.1007/s00894-020-4319-6

By:

Kumi, Ransford Oduro;
Soremekun, Opeyemi S.;
Issahaku, Abdul Rashid;
Agoni, Clement;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

East to West not North-West: Structure-Based Mechanistic Resolution of 8-Hydroxyl Replacement and Resulting Effects on the Activities of Imidazole-Based Heme Oxygenase-1 Inhibitors.

Published in:

Protein Journal, 2021, v. 40, n. 2, p. 166, doi. 10.1007/s10930-021-09969-6

By:

Okunlola, Felix O.;
Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

Functional Analysis of Single Nucleotide Polymorphism in ZUFSP Protein and Implication in Pathogenesis.

Published in:

Protein Journal, 2021, v. 40, n. 1, p. 28, doi. 10.1007/s10930-021-09962-z

By:

Ajadi, Mary B.;
Soremekun, Opeyemi S.;
Adewumi, Adeniyi T.;
Kumalo, Hezekiel M.;
Soliman, Mahmoud E. S.

Publication type:

Article

Update and Potential Opportunities in CBP [Cyclic Adenosine Monophosphate (cAMP) Response Element-Binding Protein (CREB)-Binding Protein] Research Using Computational Techniques.

Published in:

Protein Journal, 2021, v. 40, n. 1, p. 19, doi. 10.1007/s10930-020-09951-8

By:

Akinsiku, Oluwayimika E.;
Soremekun, Opeyemi S.;
Soliman, Mahmoud E. S.

Publication type:

Article

Delving into the Characteristic Features of "Menace" Mycobacterium tuberculosis Homologs: A Structural Dynamics and Proteomics Perspectives.

Published in:

Protein Journal, 2020, v. 39, n. 2, p. 118, doi. 10.1007/s10930-020-09890-4

By:

Adewumi, Adeniyi T.;
Ramharack, Pritika;
Soremekun, Opeyemi S.;
Soliman, Mahmoud E. S.

Publication type:

Article

Recruiting monomer for dimer formation: resolving the antagonistic mechanisms of novel immune check point inhibitors against Programmed Death Ligand-1 in cancer immunotherapy.

Published in:

Molecular Simulation, 2019, v. 45, n. 10, p. 777, doi. 10.1080/08927022.2019.1593977

By:

Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Agoni, Clement;
Soliman, Mahmoud E. S.

Publication type:

Article

Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Pathogenesis of Chronic Kidney Disease.

Published in:

Genes, 2022, v. 13, n. 8, p. 1460, doi. 10.3390/genes13081460

By:

Mayanja, Richard;
Kintu, Christopher;
Diabate, Oudou;
Soremekun, Opeyemi;
Oluwagbemi, Olugbenga Oluseun;
Wele, Mamadou;
Kalyesubula, Robert;
Jjingo, Daudi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Correction: Udosen et al. Meta-Analysis and Multivariate GWAS Analyses in 80,950 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits. Int. J. Mol. Sci. 2023, 24 , 2164.

Published in:

2024

By:

Udosen, Brenda;
Soremekun, Opeyemi;
Kamiza, Abram;
Machipisa, Tafadzwa;
Cheickna, Cisse;
Omotuyi, Olaposi;
Soliman, Mahmoud;
Wélé, Mamadou;
Nashiru, Oyekanmi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Correction Notice

Meta-Analysis and Multivariate GWAS Analyses in 77,850 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2164, doi. 10.3390/ijms24032164

By:

Udosen, Brenda;
Soremekun, Opeyemi;
Kamiza, Abram;
Machipisa, Tafadzwa;
Cheickna, Cisse;
Omotuyi, Olaposi;
Soliman, Mahmoud;
Wélé, Mamadou;
Nashiru, Oyekanmi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Therapeutic Path to Double Knockout: Investigating the Selective Dual-Inhibitory Mechanisms of Adenosine Receptors A1 and A2 by a Novel Methoxy-Substituted Benzofuran Derivative in the Treatment of Parkinson's Disease.

Published in:

Cell Biochemistry & Biophysics, 2021, v. 79, n. 1, p. 25, doi. 10.1007/s12013-020-00957-8

By:

Subair, Temitayo I.;
Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

An Update on the Pharmacological Usage of Curcumin: Has it Failed in the Drug Discovery Pipeline?

Published in:

Cell Biochemistry & Biophysics, 2020, v. 78, n. 3, p. 267, doi. 10.1007/s12013-020-00922-5

By:

Olotu, Fisayo;
Agoni, Clement;
Soremekun, Opeyemi;
Soliman, Mahmoud E. S.

Publication type:

Article

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans.

Published in:

Frontiers in Genetics, 2021, v. 12, p. 1, doi. 10.3389/fgene.2021.749415

By:

Soremekun, Opeyemi;
Soremekun, Chisom;
Machipisa, Tafadzwa;
Soliman, Mahmoud;
Nashiru, Oyekanmi;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Insight into the Therapeutic Potential of a Bicyclic Hydroxypyridone Compound 2‐[(2,4‐Dichlorophenyl)methyl]‐7‐hydroxy‐1,2,3,4‐tetrahydro‐8H‐pyrido[1,2‐a]pyrazin‐8‐one as COMT Inhibitor in the Treatment of Parkinson's Disease: A Molecular Dynamic Simulation Approach

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 9, p. 1, doi. 10.1002/cbdv.202100204

By:

Subair, Temitayo I.;
Akawa, Oluwole B.;
Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

Investigating the Mechanistic Inhibitory Discrepancies of Novel Halogen and Alkyl Di‐Substituted Oxadiazole‐Based Dibenzo‐Azepine‐Dione Derivatives on Poly (ADP‐Ribose) Polymerase‐1.

Published in:

Chemistry & Biodiversity, 2021, v. 18, n. 1, p. 1, doi. 10.1002/cbdv.202000802

By:

Okunlola, Felix O.;
Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

Phytomedicine in Disease Management: In-Silico Analysis of the Binding Affinity of Artesunate and Azadirachtin for Malaria Treatment.

Published in:

Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.751032

By:

Okoh, Michael P.;
Singla, Rajeev K.;
Madu, Chijioke;
Soremekun, Opeyemi;
Adejoh, Johnson;
Alli, Lukman A.;
Shen, Bairong

Publication type:

Article

Leveraging information between multiple population groups and traits improves fine-mapping resolution.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43159-5

By:

Zhou, Feng;
Soremekun, Opeyemi;
Chikowore, Tinashe;
Fatumo, Segun;
Barroso, Inês;
Morris, Andrew P.;
Asimit, Jennifer L.

Publication type:

Article

Multi-trait discovery and fine-mapping of lipid loci in 125,000 individuals of African ancestry.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41271-0

By:

Kamiza, Abram Bunya;
Touré, Sounkou M.;
Zhou, Feng;
Soremekun, Opeyemi;
Cissé, Cheickna;
Wélé, Mamadou;
Touré, Aboubacrine M.;
Nashiru, Oyekanmi;
Corpas, Manuel;
Nyirenda, Moffat;
Crampin, Amelia;
Shaffer, Jeffrey;
Doumbia, Seydou;
Zeggini, Eleftheria;
Morris, Andrew P.;
Asimit, Jennifer L.;
Chikowore, Tinashe;
Fatumo, Segun

Publication type:

Article

Genetic heterogeneity in cardiovascular disease across ancestries: Insights for mechanisms and therapeutic intervention.

Published in:

Cambridge Prisms: Precision Medicine, 2023, v. 1, p. 1, doi. 10.1017/pcm.2022.13

By:

Soremekun, Opeyemi;
Dib, Marie-Joe;
Rajasundaram, Skanda;
Fatumo, Segun;
Gill, Dipender

Publication type:

Article

An in-silico analysis of OGT gene association with diabetes mellitus.

Published in:

BMC Research Notes, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13104-024-06744-5

By:

Ayodele, Abigail O.;
Udosen, Brenda;
Oluwagbemi, Olugbenga O.;
Oladipo, Elijah K.;
Omotuyi, Idowu;
Isewon, Itunuoluwa;
Nash, Oyekanmi;
Soremekun, Opeyemi;
Fatumo, Segun

Publication type:

Article

Genetically proxied inhibition of kidney function pathways and increased risk of type 2 diabetes in Africans: A Mendelian randomization study.

Published in:

Science Progress, 2025, v. 108, n. 2, p. 1, doi. 10.1177/00368504251338631

By:

Diawara, Abdoulaye;
Traore, Mariam;
Diabaté, Oudou;
Kintu, Christopher;
Saeed, Ali Awadallah;
Abiola, Julianah Ore;
Cisse, Cheickna;
Traore, Kassim;
Wele, Mamadou;
Nash, Oyekanmi;
Doumbia, Seydou O.;
Abbas, Talib Yusuf;
Shaffer, Jeffrey G.;
Diakité, Mahamadou;
Fatumo, Segun;
Soremekun, Opeyemi

Publication type:

Article

In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure.

Published in:

BMC Research Notes, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13104-021-05879-z

By:

Udosen, Brenda;
Soremekun, Opeyemi;
Ekenna, Chinwe;
Idowu Omotuyi, Olaposi;
Chikowore, Tinashe;
Nashiru, Oyekanmi;
Fatumo, Segun

Publication type:

Article

The recent application of 3D-QSAR and docking studies to novel HIV-protease inhibitor drug discovery.

Published in:

Expert Opinion on Drug Discovery, 2020, v. 15, n. 9, p. 1095, doi. 10.1080/17460441.2020.1773428

By:

Olotu, Fisayo A.;
Agoni, Clement;
Soremekun, Opeyemi;
Soliman, Mahmoud E. S.

Publication type:

Article

Strengthening Bioinformatics and Genomics Analysis Skills in Africa for Attainment of the Sustainable Development Goals: Report of the 2nd Conference of the Nigerian Bioinformatics and Genomics Network.

Published in:

American Journal of Tropical Medicine & Hygiene, 2022, v. 107, n. 1, p. 21, doi. 10.4269/ajtmh.21-1164

By:

Isewon, Itunuoluwa;
Soremekun, Chisom;
Adebiyi, Marion;
Adetunji, Charles;
Ogunleye, Adewale Joseph;
Bajeh, Amos Orenyi;
Asani, Emmanuel Oluwatobi;
Gbadamosi, Babatunde;
Soremekun, Opeyemi;
Udosen, Brenda;
Kintu, Christopher;
Ogundokun, Roseline;
Arowolo, Micheal Olaolu;
Matiluko, Opeyemi;
Nashiru, Oyekanmi;
Adebiyi, Ezekiel;
Ekenna, Chinwe;
Fatumo, Segun

Publication type:

Article

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis.

Published in:

Pathogens, 2023, v. 12, n. 4, p. 591, doi. 10.3390/pathogens12040591

By:

Ogun, Oluwamayowa Joshua;
Soremekun, Opeyemi S.;
Thaller, Georg;
Becker, Doreen

Publication type:

Article

Weak spots inhibition in the Mycobacterium tuberculosis antigen 85C target for antitubercular drug design through selective irreversible covalent inhibitor-SER124.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 7, p. 2934, doi. 10.1080/07391102.2020.1844061

By:

Adewumi, Adeniyi T.;
Elrashedy, Ahmed;
Soremekun, Opeyemi S.;
Ajadi, Mary B.;
Soliman, Mahmoud E. S.

Publication type:

Article

Multi-dimensional structural footprint identification for the design of potential scaffolds targeting METTL3 in cancer treatment from natural compounds.

Published in:

Journal of Molecular Modeling, 2023, v. 29, n. 4, p. 1, doi. 10.1007/s00894-023-05516-5

By:

Issahaku, Abdul Rashid;
Mncube, Samukelisiwe Minenhle;
Agoni, Clement;
Kwofie, Samuel K.;
Alahmdi, Mohamed Issa;
Abo-Dya, Nader E.;
Sidhom, Peter A.;
Tawfeek, Ahmed M.;
Ibrahim, Mahmoud A. A.;
Mukelabai, Namutula;
Soremekun, Opeyemi;
Soliman, Mahmoud E. S.

Publication type:

Article

Prospecting the therapeutic edge of a novel compound (B12) over berberine in the selective targeting of Retinoid X Receptor in colon cancer.

Published in:

Journal of Molecular Modeling, 2021, v. 27, n. 8, p. 1, doi. 10.1007/s00894-021-04848-4

By:

Subair, Temitayo I.;
Soremekun, Opeyemi S.;
Olotu, Fisayo A.;
Soliman, Mahmoud E. S.

Publication type:

Article

Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach.

Published in:

Molecules, 2021, v. 26, n. 11, p. 3264, doi. 10.3390/molecules26113264

By:

Nair, Aathira Sujathan;
Oh, Jong-Min;
Koyiparambath, Vishal Payyalot;
Kumar, Sunil;
Sudevan, Sachithra Thazhathuveedu;
Soremekun, Opeyemi;
Soliman, Mahmoud E.;
Khames, Ahmed;
Abdelgawad, Mohamed A.;
Pappachen, Leena K.;
Mathew, Bijo;
Kim, Hoon

Publication type:

Article