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Loss of endophilin-B1 exacerbates Alzheimer's disease pathology.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
- Published in:
- Nature Medicine, 1999, v. 5, n. 1, p. 101, doi. 10.1038/4789
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- Publication type:
- Article
P3‐162: IPSC‐DERIVED CORTICAL NEURONS WITH A NOVEL FRAMESHIFT PSEN2 MUTATION INCREASE THE RATIO OF AGGREGATE PRONE AMYLOID BETA.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P1130, doi. 10.1016/j.jalz.2018.06.1520
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- Publication type:
- Article
Novel tricyclic pyrone compounds prevent intracellular APP C99-induced cell death.
- Published in:
- Journal of Molecular Neuroscience, 2002, v. 19, n. 1/2, p. 57, doi. 10.1007/s12031-002-0011-9
- By:
- Publication type:
- Article
Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology.
- Published in:
- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0677-7
- By:
- Publication type:
- Article
Posttranslational Modification of Ataxin-7 at Lysine 257 Prevents Autophagy-Mediated Turnover of an N-Terminal Caspase-7 Cleavage Fragment.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 48, p. 15134, doi. 10.1523/JNEUROSCI.4720-09.2009
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- Publication type:
- Article
Polyglutamine-Expanded Androgen Receptor Truncation Fragments Activate a Bax-Dependent Apoptotic Cascade Mediated by DP5/Hrk.
- Published in:
- Journal of Neuroscience, 2009, v. 29, n. 7, p. 1987, doi. 10.1523/JNEUROSCI.4072-08.2009
- By:
- Publication type:
- Article
MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex.
- Published in:
- Life Science Alliance, 2023, v. 6, n. 8, p. 1, doi. 10.26508/lsa.202201525
- By:
- Publication type:
- Article
Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity.
- Published in:
- Acta Neuropathologica Communications, 2023, v. 11, n. 1, p. 1, doi. 10.1186/s40478-023-01665-z
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- Publication type:
- Article
Alternative splicing in a presenilin 2 variant associated with Alzheimer disease.
- Published in:
- Annals of Clinical & Translational Neurology, 2019, v. 6, n. 4, p. 762, doi. 10.1002/acn3.755
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- Publication type:
- Article
Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7.
- Published in:
- Science Translational Medicine, 2018, v. 10, n. 465, p. 1, doi. 10.1126/scitranslmed.aap8677
- By:
- Publication type:
- Article
Neuronal susceptibility to beta‐amyloid toxicity and ischemic injury involves histone deacetylase‐2 regulation of endophilin‐B1.
- Published in:
- Brain Pathology, 2019, v. 29, n. 2, p. 164, doi. 10.1111/bpa.12647
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- Publication type:
- Article
Recombinant adeno-associated viral ( rAAV) vectors mediate efficient gene transduction in cultured neonatal and adult microglia.
- Published in:
- Journal of Neurochemistry, 2016, v. 136, p. 49, doi. 10.1111/jnc.13081
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- Publication type:
- Article
Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 14, p. 3908, doi. 10.1093/hmg/ddv121
- By:
- Publication type:
- Article
Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7.
- Published in:
- Human Molecular Genetics, 2013, v. 22, n. 5, p. 890, doi. 10.1093/hmg/dds495
- By:
- Publication type:
- Article
Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Pancreatic β-Cell Failure and Diabetes in Mice With a Deletion Mutation of the Endoplasmic Reticulum Molecular Chaperone Gene P58<sup>IPK</sup>.
- Published in:
- Diabetes, 2005, v. 54, n. 4, p. 1074, doi. 10.2337/diabetes.54.4.1074
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- Publication type:
- Article
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein.
- Published in:
- Mammalian Genome, 2006, v. 17, n. 2, p. 103, doi. 10.1007/s00335-005-0096-x
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- Publication type:
- Article
Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients.
- Published in:
- Acta Neuropathologica, 2018, v. 136, n. 3, p. 425, doi. 10.1007/s00401-018-1852-9
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- Publication type:
- Article
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.
- Published in:
- Nature Neuroscience, 2014, v. 17, n. 9, p. 1180, doi. 10.1038/nn.3787
- By:
- Publication type:
- Article
Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport.
- Published in:
- Nature Neuroscience, 2006, v. 9, n. 10, p. 1302, doi. 10.1038/nn1750
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- Publication type:
- Article
4E-BP1 Protects Neurons from Misfolded Protein Stress and Parkinson's Disease Toxicity by Inducing the Mitochondrial Unfolded Protein Response.
- Published in:
- Journal of Neuroscience, 2020, v. 40, n. 45, p. 8734, doi. 10.1523/JNEUROSCI.0940-20.2020
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- Publication type:
- Article
CTCF cis-Regulates Trinucleotide Repeat Instability in an Epigenetic Manner: A Novel Basis for Mutational Hot Spot Determination.
- Published in:
- PLoS Genetics, 2008, v. 4, n. 11, p. 1, doi. 10.1371/journal.pgen.1000257
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- Publication type:
- Article
The pro‐inflammatory microRNA miR‐155 influences fibrillar β‐Amyloid<sub>1</sub><sub>‐42</sub> catabolism by microglia.
- Published in:
- Glia, 2021, v. 69, n. 7, p. 1736, doi. 10.1002/glia.23988
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- Publication type:
- Article
β-synuclein modulates α-synuclein neurotoxicity by reducing α-synuclein protein expression.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 20, p. 3002, doi. 10.1093/hmg/ddl242
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- Publication type:
- Article
Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 19, p. 2972, doi. 10.1093/hmg/ddl226
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- Publication type:
- Article
Loss of endogenous androgen receptor protein accelerates motor neuron degeneration and accentuates androgen insensitivity in a mouse model of X-linked spinal and bulbar muscular atrophy.
- Published in:
- Human Molecular Genetics, 2006, v. 15, n. 14, p. 2225, doi. 10.1093/hmg/ddl148
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- Publication type:
- Article
Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 1, p. 53
- By:
- Publication type:
- Article
Increased Vulnerability of Hippocampal Neurons from Presenilin-1 Mutant Knock-In Mice to Amyloid β-Peptide Toxicity: Central Roles of Superoxide Production and Caspase Activation.
- Published in:
- Journal of Neurochemistry, 1999, v. 72, n. 3, p. 1019, doi. 10.1046/j.1471-4159.1999.0721019.x
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- Publication type:
- Article
Increased Activity-Regulating and Neuroprotective Efficacy of α-Secretase-Derived Secreted Amyloid Precursor Protein Conferred by a C-Terminal Heparin-Binding Domain.
- Published in:
- Journal of Neurochemistry, 1996, v. 67, n. 5, p. 1882, doi. 10.1046/j.1471-4159.1996.67051882.x
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- Publication type:
- Article
cDNA Cloning and Chromosome Mapping of the Human Fe65 Gene: Interaction of the Conserved Cytoplasmic Domains of the Human β-amyloid Precursor Protein and Its Homologues with the Mouse Fe65 Protein.
- Published in:
- Human Molecular Genetics, 1996, v. 5, n. 10, p. 1589
- By:
- Publication type:
- Article
Bax Interacting Factor-1 Promotes Survival and Mitochondrial Elongation in Neurons.
- Published in:
- Journal of Neuroscience, 2014, v. 34, n. 7, p. 2674, doi. 10.1523/JNEUROSCI.4074-13.2014
- By:
- Publication type:
- Article
Declines in Drpl and Parkin Expression Underlie DNA Damage-Induced Changes in Mitochondrial Length and Neuronal Death.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 4, p. 1357, doi. 10.1523/JNEUROSCI.3365-12.2013
- By:
- Publication type:
- Article
Spinocerebellar Ataxia Type 7 Cerebellar Disease Requires the Coordinated Action of Mutant Ataxin-7 in Neurons and Glia, and Displays Non-Cell-Autonomous Bergmann Glia Degeneration.
- Published in:
- Journal of Neuroscience, 2011, v. 31, n. 45, p. 16269, doi. 10.1523/JNEUROSCI.4000-11.2011
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- Publication type:
- Article