Works by Somsen, Govert W.

Results: 65

Middle-Up Characterization of the Monoclonal Antibody Infliximab by Capillary Zone Electrophoresis-Mass Spectrometry.

Published in:

LC-GC Europe, 2019, v. 32, n. 3, p. 130

By:

Michalíková, Klára;
Dominguez-Vega, Elena;
Somsen, Govert W.;
Haselberg, Rob

Publication type:

Article

High throughput screening and identification of coagulopathic snake venom proteins and peptides using nanofractionation and proteomics approaches.

Published in:

PLoS Neglected Tropical Diseases, 2020, v. 14, n. 4, p. 1, doi. 10.1371/journal.pntd.0007802

By:

Slagboom, Julien;
Mladić, Marija;
Xie, Chunfang;
Kazandjian, Taline D.;
Vonk, Freek;
Somsen, Govert W.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Microfluidic ion stripper for removal of trifluoroacetic acid from mobile phases used in HILIC-MS of intact proteins.

Published in:

Analytical & Bioanalytical Chemistry, 2021, v. 413, n. 17, p. 4379, doi. 10.1007/s00216-021-03414-4

By:

Wouters, Sam;
Eeltink, Sebastiaan;
Haselberg, Rob;
Somsen, Govert W.;
Gargano, Andrea F. G.

Publication type:

Article

On-line coupling of SPE and CE-MS for peptide analysis.

Published in:

Electrophoresis, 2007, v. 28, n. 9, p. 1319, doi. 10.1002/elps.200600403

By:

Tempels, F. W. Alexander;
Underberg, Willy J. M.;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Comparison of atmospheric pressure photoionization and ESI for CZE-MS of drugs.

Published in:

Electrophoresis, 2007, v. 28, n. 9, p. 1444, doi. 10.1002/elps.200600504

By:

Hommerson, Paul;
Khan, Amjad M.;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Efficient and highly reproducible capillary electrophoresis–mass spectrometry of peptides using Polybrene-poly(vinyl sulfonate)-coated capillaries.

Published in:

Electrophoresis, 2006, v. 27, n. 11, p. 2091, doi. 10.1002/elps.200500915

By:

Jonatan R. Catai;
Javier Sastre Toraño;
Gerhardus J. de Jong;
Govert W. Somsen

Publication type:

Article

On-line capillary electrophoresis-mass spectrometry using dopant-assisted atmospheric pressure photoionization: Setup and system performance.

Published in:

Electrophoresis, 2005, v. 26, n. 1, p. 146, doi. 10.1002/elps.200406101

By:

Roelof Mol;
Gerhardus J. de Jong;
Govert W. Somsen

Publication type:

Article

Efficient and reproducible analysis of peptides by capillary electrophoresis using noncovalently bilayer-coated capillaries.

Published in:

Electrophoresis, 2004, v. 25, n. 6, p. 817, doi. 10.1002/elps.200305720

By:

Jonatan R. Catai;
Govert W. Somsen;
Gerhardus J. de Jong

Publication type:

Article

Feasibility of nonvolatile buffers in capillary electrophoresis-electrospray ionization-mass spectrometry of proteins.

Published in:

Electrophoresis, 2004, v. 25, n. 1, p. 43, doi. 10.1002/elps.200305695

By:

Jonas H. C. Eriksson;
Roelof Mol;
Govert W. Somsen;
Wouter L. J. Hinrichs;
Henderik W. Frijlink;
Gerhardus J. de Jong

Publication type:

Article

Capillary electrokinetic separation techniques for profiling of drugs and related products.

Published in:

Electrophoresis, 2001, v. 22, n. 12, p. 2542, doi. 10.1002/1522-2683(200107)22:12<2542::AID-ELPS2542>3.0.CO;2-3

By:

Hilhorst, Martijn J.;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Towards a general approach for the impurity profiling of drugs by micellar electrokinetic chromatography.

Published in:

Electrophoresis, 2001, v. 22, n. 7, p. 1337, doi. 10.1002/1522-2683(200105)22:7<1337::AID-ELPS1337>3.0.CO;2-8

By:

Hilhorst, Martin J.;
Derksen, Astrid F.;
Steringa, Melle;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins.

Published in:

Biomedicines, 2020, v. 8, n. 9, p. 297, doi. 10.3390/biomedicines8090297

By:

Xie, Chunfang;
Albulescu, Laura-Oana;
Bittenbinder, Mátyás A.;
Somsen, Govert W.;
Vonk, Freek J.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Varespladib Inhibits the Phospholipase A2 and Coagulopathic Activities of Venom Components from Hemotoxic Snakes.

Published in:

Biomedicines, 2020, v. 8, n. 6, p. 165, doi. 10.3390/biomedicines8060165

By:

Xie, Chunfang;
Albulescu, Laura-Oana;
Still, Kristina B. M.;
Slagboom, Julien;
Zhao, Yumei;
Jiang, Zhengjin;
Somsen, Govert W.;
Vonk, Freek J.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

A Combined Bioassay and Nanofractionation Approach to Investigate the Anticoagulant Toxins of Mamba and Cobra Venoms and Their Inhibition by Varespladib.

Published in:

Toxins, 2022, v. 14, n. 11, p. 736, doi. 10.3390/toxins14110736

By:

Arrahman, Arif;
Kazandjian, Taline D.;
Still, Kristina B. M.;
Slagboom, Julien;
Somsen, Govert W.;
Vonk, Freek J.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Quantitative assessment of polymer molecular shape based on changes in the slope of the Mark‐Houwink plot derived from size‐exclusion chromatography with triple detection.

Published in:

Journal of Applied Polymer Science, 2024, v. 141, n. 9, p. 1, doi. 10.1002/app.55013

By:

Bos, Tijmen S.;
Philipsen, Harry J. A.;
Staal, Bastiaan B. P.;
Purmova, Jindra;
Beerends, René J. L.;
Buijtenhuijs, Ab;
Karlson, Leif;
Schoenmakers, Peter J.;
Somsen, Govert W.

Publication type:

Article

MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N -Glycosylation.

Published in:

Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.02049

By:

Sénard, Thomas;
Gargano, Andrea F. G.;
Falck, David;
de Taeye, Steven W.;
Rispens, Theo;
Vidarsson, Gestur;
Wuhrer, Manfred;
Somsen, Govert W.;
Domínguez-Vega, Elena

Publication type:

Article

Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib.

Published in:

Toxins, 2021, v. 13, n. 5, p. 302, doi. 10.3390/toxins13050302

By:

Kazandjian, Taline D.;
Arrahman, Arif;
Still, Kristina B. M.;
Somsen, Govert W.;
Vonk, Freek J.;
Casewell, Nicholas R.;
Wilkinson, Mark C.;
Kool, Jeroen

Publication type:

Article

Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics.

Published in:

Toxins, 2020, v. 12, n. 1, p. 53, doi. 10.3390/toxins12010053

By:

Xie, Chunfang;
Slagboom, Julien;
Albulescu, Laura-Oana;
Bruyneel, Ben;
Still, Kristina B. M.;
Vonk, Freek J.;
Somsen, Govert W.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Multipurpose HTS Coagulation Analysis: Assay Development and Assessment of Coagulopathic Snake Venoms.

Published in:

Toxins, 2017, v. 9, n. 12, p. 382, doi. 10.3390/toxins9120382

By:

Still, Kristina B. M.;
Nandlal, Randjana S. S.;
Slagboom, Julien;
Somsen, Govert W.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms.

Published in:

Toxins, 2015, v. 7, n. 7, p. 2336, doi. 10.3390/toxins7072336

By:

Otvos, Reka A.;
Iyer, Janaki Krishnamoorthy;
van Elk, René;
Ulens, Chris;
Niessen, Wilfried M. A.;
Somsen, Govert W.;
Kini, R. Manjunatha;
Smit, August B.;
Kool, Jeroen

Publication type:

Article

Affinity profiling of monoclonal antibody and antibody-drug-conjugate preparations by coupled liquid chromatography-surface plasmon resonance biosensing.

Published in:

Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 30, p. 7837, doi. 10.1007/s00216-018-1414-y

By:

Lakayan, Dina;
Haselberg, Rob;
Gahoual, Rabah;
Somsen, Govert W.;
Kool, Jeroen

Publication type:

Article

Liquid chromatographic nanofractionation with parallel mass spectrometric detection for the screening of plasmin inhibitors and (metallo)proteinases in snake venoms.

Published in:

Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 23, p. 5751, doi. 10.1007/s00216-018-1253-x

By:

Zietek, Barbara M.;
Mayar, Morwarid;
Slagboom, Julien;
Bruyneel, Ben;
Vonk, Freek J.;
Somsen, Govert W.;
Casewell, Nicholas R.;
Kool, Jeroen

Publication type:

Article

Chiral capillary electrophoresis with UV-excited fluorescence detection for the enantioselective analysis of 9-fluorenylmethoxycarbonyl-derivatized amino acids.

Published in:

Analytical & Bioanalytical Chemistry, 2018, v. 410, n. 20, p. 4979, doi. 10.1007/s00216-018-1148-x

By:

Prior, Amir;
Coliva, Giulia;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Evaluation of the sensitivity of miniaturized liquid chromatography-electrospray ionization-mass spectrometry for pharmaceutical analysis.

Published in:

Journal of Separation Science, 2005, v. 28, n. 14, p. 1796

By:

Joop C. M. Waterval;
Govert W. Somsen;
Gerhardus J. de Jong

Publication type:

Article

Limited Lactosylation of Beta-Lactoglobulin from Cow's Milk Exerts Strong Influence on Antigenicity and Degranulation of Mast Cells.

Published in:

Nutrients, 2021, v. 13, n. 6, p. 2041, doi. 10.3390/nu13062041

By:

Bosman, Gerlof P.;
Oliveira, Sergio;
Simons, Peter J.;
Sastre Torano, Javier;
Somsen, Govert W.;
Knippels, Leon M. J.;
Haselberg, Rob;
Pieters, Roland J.;
Garssen, Johan;
Knipping, Karen

Publication type:

Article

Platinum(II) as Bifunctional Linker in Antibody-Drug Conjugate Formation: Coupling of a 4-Nitrobenzo-2-oxa-1,3-diazole Fluorophore to Trastuzumab as a Model.

Published in:

ChemMedChem, 2015, v. 10, n. 5, p. 797, doi. 10.1002/cmdc.201402496

By:

Waalboer, Dennis C. J.;
Muns, Joey A.;
Sijbrandi, Niels J.;
Schasfoort, Richard B. M.;
Haselberg, Rob;
Somsen, Govert W.;
Houthoff, Hendrik‐Jan;
van Dongen, Guus A. M. S.

Publication type:

Article

Implementation of at‐line capillary zone electrophoresis for fast and reliable determination of adenovirus concentrations in vaccine manufacturing.

Published in:

Electrophoresis, 2019, v. 40, n. 18/19, p. 2277, doi. 10.1002/elps.201900068

By:

Tricht, Ewoud;
Geurink, Lars;
Galindo Garre, Francisca;
Schenning, Martijn;
Backus, Harold;
Germano, Marta;
Somsen, Govert W.;
Sänger – van de Griend, Cari E.

Publication type:

Article

CE‐MS for metabolomics: Developments and applications in the period 2016–2018.

Published in:

Electrophoresis, 2019, v. 40, n. 1, p. 165, doi. 10.1002/elps.201800323

By:

Ramautar, Rawi;
Somsen, Govert W.;
Jong, Gerhardus J.

Publication type:

Article

Inside Front Cover: CE‐MS for metabolomics: Developments and applications in the period 2016–2018.

Published in:

Electrophoresis, 2019, v. 40, n. 1, p. NA, doi. 10.1002/elps.201970002

By:

Ramautar, Rawi;
Somsen, Govert W.;
Jong, Gerhardus J.

Publication type:

Article

CE-MS for metabolomics: Developments and applications in the period 2014-2016.

Published in:

Electrophoresis, 2017, v. 38, n. 1, p. 190, doi. 10.1002/elps.201600370

By:

Ramautar, Rawi;
Somsen, Govert W.;
Jong, Gerhardus J.

Publication type:

Article

Enantioselective analysis of proteinogenic amino acids in cerebrospinal fluid by capillary electrophoresis-mass spectrometry.

Published in:

Electrophoresis, 2016, v. 37, n. 17/18, p. 2410, doi. 10.1002/elps.201600015

By:

Prior, Amir;
Sánchez‐Hernández, Laura;
Sastre‐Toraño, Javier;
Marina, Maria Luisa;
Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Developments in coupled solid-phase extraction-capillary electrophoresis 2013-2015.

Published in:

Electrophoresis, 2016, v. 37, n. 1, p. 35, doi. 10.1002/elps.201500401

By:

Ramautar, Rawi;
Somsen, Govert W.;
Jong, Gerhardus J.

Publication type:

Article

CE-MS for metabolomics: Developments and applications in the period 2012-2014.

Published in:

Electrophoresis, 2015, v. 36, n. 1, p. 212, doi. 10.1002/elps.201400388

By:

Ramautar, Rawi;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Evaluation of fritless solid-phase extraction coupled on-line with capillary electrophoresis-mass spectrometry for the analysis of opioid peptides in cerebrospinal fluid.

Published in:

Electrophoresis, 2014, v. 35, n. 20, p. 2996, doi. 10.1002/elps.201400293

By:

Medina‐Casanellas, Silvia;
Tak, Yvonne H.;
Benavente, Fernando;
Sanz‐Nebot, Victoria;
Toraño, Javier Sastre;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Developments in coupled solid-phase extraction-capillary electrophoresis 2011-2013.

Published in:

Electrophoresis, 2014, v. 35, n. 1, p. 128, doi. 10.1002/elps.201300335

By:

Ramautar, Rawi;
Somsen, Govert W.;
Jong, Gerhardus J.

Publication type:

Article

Micellar electrokinetic chromatography-electrospray ionization mass spectrometry employing a volatile surfactant for the analysis of amino acids in human urine.

Published in:

Electrophoresis, 2013, v. 34, n. 18, p. 2615, doi. 10.1002/elps.201300247

By:

Moreno‐González, David;
Toraño, Javier Sastre;
Gámiz‐Gracia, Laura;
García‐Campaña, Ana M.;
Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

CE- MS for the analysis of intact proteins 2010-2012.

Published in:

Electrophoresis, 2013, v. 34, n. 1, p. 99, doi. 10.1002/elps.201200439

By:

Haselberg, Rob;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

CE-MS for metabolomics: Developments and applications in the period 2010-2012.

Published in:

Electrophoresis, 2013, v. 34, n. 1, p. 86, doi. 10.1002/elps.201200390

By:

Ramautar, Rawi;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Profiling of erythropoietin products by capillary electrophoresis with native fluorescence detection.

Published in:

Electrophoresis, 2012, v. 33, n. 19/20, p. 2996, doi. 10.1002/elps.201200303

By:

de Kort, Bregje J.;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Developments in coupled solid-phase extraction-capillary electrophoresis 2009-2011.

Published in:

Electrophoresis, 2012, v. 33, n. 1, p. 243, doi. 10.1002/elps.201100453

By:

Ramautar, Rawi;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

CE-MS for metabolomics: Developments and applications in the period 2008-2010.

Published in:

Electrophoresis, 2010, v. 32, n. 1, p. 52, doi. 10.1002/elps.201000378

By:

Ramautar, Rawi;
Mayboroda, Oleg A.;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Capillary electrophoresis-mass spectrometry for the analysis of intact proteins 2007-2010.

Published in:

Electrophoresis, 2010, v. 32, n. 1, p. 66, doi. 10.1002/elps.201000364

By:

Haselberg, Rob;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Lamp-based wavelength-resolved fluorescence detection for protein capillary electrophoresis: Setup and detector performance.

Published in:

Electrophoresis, 2010, v. 31, n. 17, p. 2861, doi. 10.1002/elps.201000246

By:

de Kort, Bregje J.;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Evaluation of CE methods for global metabolic profiling of urine.

Published in:

Electrophoresis, 2010, v. 31, n. 14, p. 2319, doi. 10.1002/elps.200900750

By:

Ramautar, Rawi;
Toraño, Javier Sastre;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Influence of the BGE composition on analyte response in CD-mediated NACE-MS.

Published in:

Electrophoresis, 2010, v. 31, n. 7, p. 1157, doi. 10.1002/elps.200900649

By:

Servais, Anne-Catherine;
Fillet, Marianne;
Mol, Roelof;
Rousseau, Anne;
Crommen, Jacques;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Recent developments in coupled SPE-CE.

Published in:

Electrophoresis, 2010, v. 31, n. 1, p. 44, doi. 10.1002/elps.200900510

By:

Ramautar, Rawi;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

CE-MS in metabolomics.

Published in:

Electrophoresis, 2009, v. 30, n. 1, p. 276, doi. 10.1002/elps.200800512

By:

Ramautar, Rawi;
Somsen, Govert W.;
de Jong, Gerhardus J.

Publication type:

Article

Cyclodextrin-based nonaqueous electrokinetic chromatography with UV and mass spectrometric detection: Application to the impurity profiling of amiodarone.

Published in:

Electrophoresis, 2008, v. 29, n. 17, p. 3575, doi. 10.1002/elps.200800074

By:

Mol, Roelof;
de Jong, Gerhardus J.;
Somsen, Govert W.

Publication type:

Article

Capillary electrophoresis-time of flight-mass spectrometry using noncovalently bilayer-coated capillaries for the analysis of amino acids in human urine.

Published in:

Electrophoresis, 2008, v. 29, n. 12, p. 2714, doi. 10.1002/elps.200700929

By:

Ramautar, Rawi;
Mayboroda, Oleg A.;
Derks, Rico J. E.;
van Nieuwkoop, Cees;
van Dissel, Jaap T.;
Somsen, Govert W.;
Deelder, André M.;
de Jong, Gerhardus J.

Publication type:

Article

Use of large-volume sample stacking in on-line solid-phase extraction-capillary electrophoresis for improved sensitivity.

Published in:

Electrophoresis, 2008, v. 29, n. 6, p. 1339, doi. 10.1002/elps.200700636

By:

Puig, Patricia;
Tempels, F. W. Alexander;
Somsen, Govert W.;
de Jong, Gerhardus J.;
Borrull, Francesc;
Aguilar, Carme;
Calull, Marta

Publication type:

Article