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Grist for the MLL: how do MLL oncogenic fusion proteins generate leukemia stem cells?
Published in:
2010
By:
- Somervaille, Tim;
- Cleary, Michael;
- Somervaille, Tim C P;
- Cleary, Michael L
Publication type:
journal article
Identification of curaxin as a potential new therapeutic for JAK2 V617F mutant patients.
Published in:
PLoS ONE, 2023, v. 17, n. 5, p. 1, doi. 10.1371/journal.pone.0286412
By:
- Pearson, Stella;
- Blance, Rognvald;
- Yan, Fei;
- Hsieh, Ya-Ching;
- Geary, Bethany;
- Amaral, Fabio M. R.;
- Somervaille, Tim C. P.;
- Kirschner, Kristina;
- Whetton, Anthony D.;
- Pierce, Andrew
Publication type:
Article
A three‐gene leukaemic stem cell signature score is robustly prognostic in chronic myelomonocytic leukaemia.
Published in:
British Journal of Haematology, 2023, v. 201, n. 2, p. 302, doi. 10.1111/bjh.18681
By:
- Wang, Yu‐Hung;
- Yao, Chi‐Yuan;
- Lin, Chien‐Chin;
- Gurashi, Kristian;
- Amaral, Fabio M. R.;
- Bossenbroek, Hasse;
- Jerez, Andres;
- Somervaille, Tim C. P.;
- Binder, Moritz;
- Patnaik, Mrinal M.;
- Hou, Hsin‐An;
- Chou, Wen‐Chien;
- Batta, Kiran;
- Wiseman, Daniel H.;
- Tien, Hwei‐Fang
Publication type:
Article
Elevated plasma 2-hydroxyglutarate in acute myeloid leukaemia: association with the IDH1 SNP rs11554137 and severe renal impairment.
Published in:
British Journal of Haematology, 2014, v. 166, n. 1, p. 145, doi. 10.1111/bjh.12826
By:
- Wiseman, Daniel H.;
- Small, Helen F.;
- Wilks, Deepti P.;
- Waddell, Ian D.;
- Dennis, Michael W.;
- Ogilvie, Donald J.;
- Somervaille, Tim C. P.
Publication type:
Article
Very high frequencies of leukaemia-initiating cells in precursor T-acute lymphoblastic leukaemia may be obscured by cryopreservation.
Published in:
British Journal of Haematology, 2013, v. 163, n. 4, p. 538, doi. 10.1111/bjh.12511
By:
- Greystoke, Brigit F.;
- Huang, Xu;
- Wilks, Deepti P.;
- Atkinson, Shayne;
- Somervaille, Tim C. P.
Publication type:
Article
Targeted nanopore sequencing for the identification of ABCB1 promoter translocations in cancer.
Published in:
2020
By:
- Williams, Mark S.;
- Basma, Naseer J.;
- Amaral, Fabio M. R.;
- Williams, Gillian;
- Weightman, John P.;
- Breitwieser, Wolfgang;
- Nelson, Louisa;
- Taylor, Stephen S.;
- Wiseman, Daniel H.;
- Somervaille, Tim C. P.
Publication type:
journal article
Phosphorylation of the Leukemic Oncoprotein EVI1 on Serine 196 Modulates DNA Binding, Transcriptional Repression and Transforming Ability.
Published in:
PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0066510
By:
- White, Daniel J.;
- Unwin, Richard D.;
- Bindels, Eric;
- Pierce, Andrew;
- Teng, Hsiang-Ying;
- Muter, Joanne;
- Greystoke, Brigit;
- Somerville, Tim D.;
- Griffiths, John;
- Lovell, Simon;
- Somervaille, Tim C. P.;
- Delwel, Ruud;
- Whetton, Anthony D.;
- Meyer, Stefan
Publication type:
Article
The Diverse Consequences of FOXC1 Deregulation in Cancer.
Published in:
Cancers, 2019, v. 11, n. 2, p. 184, doi. 10.3390/cancers11020184
By:
- Gilding, L. Niall;
- Somervaille, Tim C. P.
Publication type:
Article
Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.
Published in:
Nature, 2008, v. 455, n. 7217, p. 1205, doi. 10.1038/nature07284
By:
- Wang, Zhong;
- Smith, Kevin S.;
- Murphy, Mark;
- Piloto, Obdulio;
- Somervaille, Tim C. P.;
- Cleary, Michael L.
Publication type:
Article
A retrospective real-world study of the current treatment pathways for myelofibrosis in the United Kingdom: the REALISM UK study.
Published in:
Therapeutic Advances in Hematology, 2022, v. 13, p. 1, doi. 10.1177/20406207221084487
By:
- Mead, Adam J.;
- Butt, Nauman M.;
- Nagi, Waseem;
- Whiteway, Alastair;
- Kirkpatrick, Suriya;
- Rinaldi, Ciro;
- Roughley, Catherine;
- Ackroyd, Sam;
- Ewing, Joanne;
- Neelakantan, Pratap;
- Garg, Mamta;
- Tucker, David;
- Murphy, John;
- Patel, Hitesh;
- Bains, Rozinder;
- Chiu, Gavin;
- Hickey, Joe;
- Harrison, Claire;
- Somervaille, Tim C. P.
Publication type:
Article
Fatal invasive aspergillosis of the larynx.
Published in:
European Journal of Haematology, 2013, v. 90, n. 4, p. 354, doi. 10.1111/ejh.12054
By:
- Williams, Mark S.;
- Ali, Nisha;
- Nonaka, Daisuke;
- Bloor, Adrian J.;
- Somervaille, Tim C. P.
Publication type:
Article
Blast cells surviving acute myeloid leukemia induction therapy are in cycle with a signature of FOXM1 activity.
Published in:
2021
By:
- Williams, Mark S.;
- Basma, Naseer J.;
- Amaral, Fabio M. R.;
- Wiseman, Daniel H.;
- Somervaille, Tim C. P.
Publication type:
journal article
A stress-responsive enhancer induces dynamic drug resistance in acute myeloid leukemia.
Published in:
2020
By:
- Williams, Mark S.;
- Amaral, Fabio M. R.;
- Simeoni, Fabrizio;
- Somervaille, Tim C. P.;
- Amaral, Fabio Mr;
- Somervaille, Tim Cp
Publication type:
journal article
Sudden onset bilateral deafness as a presentation of chronic myeloid leukaemia.
Published in:
British Journal of Haematology, 2013, v. 160, n. 1, p. 3, doi. 10.1111/bjh.12098
By:
- Alimam, Samah M.;
- Mamat, Mohd K.;
- Kulkarni, Samar;
- Somervaille, Tim C. P.
Publication type:
Article
Intraocular relapse of childhood acute lymphoblastic leukaemia.
Published in:
British Journal of Haematology, 2003, v. 121, n. 2, p. 280, doi. 10.1046/j.1365-2141.2003.04280.x
By:
- Somervaille, Tim C. P.;
- Hann, Ian M.;
- Harrison, Georgina;
- Eden, Tim O.B.;
- Gibson, Brenda E.;
- Hill, Frank G.;
- Mitchell, Chris;
- Kinsey, Sally E.;
- Vora, Ajay J.;
- Lilleyman, John S.
Publication type:
Article
Different levels of p38 MAP kinase activity mediate distinct biological effects in primary human erythroid progenitors.
Published in:
British Journal of Haematology, 2003, v. 120, n. 5, p. 876, doi. 10.1046/j.1365-2141.2003.04204.x
By:
- Somervaille, Tim C. P.;
- Linch, David C.;
- Khwaja, Asim
Publication type:
Article
Variable product purity and functional capacity after CD34 selection: a direct comparison of the CliniMACS<sup>®</sup> (v2·1) and Isolex<sup>®</sup> 300i (v2·5) clinical scale devices.
Published in:
British Journal of Haematology, 2002, v. 118, n. 1, p. 117, doi. 10.1046/j.1365-2141.2002.03561.x
By:
- Watts, Michael J.;
- Somervaille, Tim C. P.;
- Ings, Stuart J.;
- Ahmed, Forhad;
- Khwaja, Asim;
- Yong, Kwee;
- Linch, David C.
Publication type:
Article
EVI1 oncoprotein expression and CtBP1-association oscillate through the cell cycle.
Published in:
Molecular Biology Reports, 2020, v. 47, n. 10, p. 8293, doi. 10.1007/s11033-020-05829-1
By:
- Paredes, Roberto;
- Schneider, Marion;
- Pearson, Stella;
- Teng, Hsiang Yin;
- Kelly, James R.;
- Pierce, Andrew;
- Somervaille, Tim C. P.;
- Whetton, Anthony D.;
- Meyer, Stefan
Publication type:
Article
Oligomeric self-association contributes to E2A-PBX1-mediated oncogenesis.
Published in:
Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-41393-w
By:
- Lin, Chiou-Hong;
- Wang, Zhong;
- Duque-Afonso, Jesús;
- Wong, Stephen Hon-Kit;
- Demeter, Janos;
- Loktev, Alexander V.;
- Somervaille, Tim C. P.;
- Jackson, Peter K.;
- Cleary, Michael L.
Publication type:
Article

Found: 19