OpenURL Connection Search

Select item for more details and to access through your institution.

Insulin Concentration Modulates Hepatic Lipid Accumulation in Mice in Part via Transcriptional Regulation of Fatty Acid Transport Proteins.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038952
By:
- Softic, Samir;
- Kirby, Michelle;
- Berger, Nicholas G.;
- Shroyer, Noah F.;
- Woods, Stephen C.;
- Kohli, Rohit
Publication type:
Article
Stratification by obesity class, rather than age, can identify a higher percent of children at risk for non‐alcoholic fatty liver disease and metabolic dysfunction.
Published in:
Pediatric Obesity, 2022, v. 17, n. 3, p. 1, doi. 10.1111/ijpo.12862
By:
- Radulescu, Aurelia;
- Dugan, Adam J.;
- Killian, Mary;
- Attia, Suzanna L.;
- Mouzaki, Marialena;
- Fuchs, George J.;
- Kohli, Rohit;
- Bada, Henrietta;
- Kern, Philip A.;
- Softic, Samir
Publication type:
Article
Role of p110a subunit of PI3-kinase in skeletal muscle mitochondrial homeostasis and metabolism.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11265-y
By:
- Li, Mengyao Ella;
- Lauritzen, Hans P. M. M.;
- Wang, Chih-Hao;
- Cai, Weikang;
- Brandao, Bruna B.;
- Sakaguchi, Masaji;
- Hirshman, Michael F.;
- Kahn, C. Ronald;
- O'Neill, Brian T.;
- Softic, Samir;
- Tao, Rongya
Publication type:
Article
Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors.
Published in:
EMBO Journal, 2018, v. 37, n. 24, p. N.PAG, doi. 10.15252/embj.2018100409
By:
- Rao, Tata Nageswara;
- Gupta, Manoj K;
- Softic, Samir;
- Wang, Leo D;
- Jang, Young C;
- Thomou, Thomas;
- Bezy, Olivier;
- Kulkarni, Rohit N;
- Kahn, C Ronald;
- Wagers, Amy J
Publication type:
Article
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
Published in:
2018
By:
- Softic, Samir;
- Gupta, Manoj K;
- Wang, Guo-Xiao;
- Fujisaka, Shiho;
- O'Neill, Brian T;
- Rao, Tata Nageswara;
- Willoughby, Jennifer;
- Harbison, Carole;
- Fitzgerald, Kevin;
- Ilkayeva, Olga;
- Newgard, Christopher B;
- Cohen, David E;
- Kahn, C Ronald
Publication type:
journal article
Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling.
Published in:
2017
By:
- Softic, Samir;
- Gupta, Manoj K.;
- Guo-Xiao Wang;
- Shiho Fujisaka;
- O'Neill, Brian T.;
- Rao, Tata Nageswara;
- Willoughby, Jennifer;
- Harbison, Carole;
- Fitzgerald, Kevin;
- Ilkayeva, Olga;
- Newgard, Christopher B.;
- Cohen, David E.;
- Kahn, C. Ronald;
- Wang, Guo-Xiao;
- Fujisaka, Shiho
Publication type:
journal article
Antibiotic effects on gut microbiota and metabolism are host dependent.
Published in:
2016
By:
- Shiho Fujisaka;
- Ussar, Siegfried;
- Clish, Clary;
- Devkota, Suzanne;
- Dreyfuss, Jonathan M.;
- Masaji Sakaguchi;
- Marion Soto;
- Masahiro Konishi;
- Softie, Samir;
- Altindis, Emrah;
- Ning Li;
- Cerber, Georg;
- Bry, Lynn;
- Kahn, C. Ronald;
- Fujisaka, Shiho;
- Sakaguchi, Masaji;
- Soto, Marion;
- Konishi, Masahiro;
- Softic, Samir;
- Li, Ning
Publication type:
journal article
Insulin and IGF-1 receptors regulate FoxO-mediated signaling in muscle proteostasis.
Published in:
2016
By:
- O'Neill, Brian T.;
- Lee, Kevin Y.;
- Klaus, Katherine;
- Softic, Samir;
- Krumpoch, Megan T.;
- Fentz, Joachim;
- Stanford, Kristin I.;
- Robinson, Matthew M.;
- Weikang Cai;
- Kleinridders, Andre;
- Pereira, Renata O.;
- Hirshman, Michael F.;
- Abel, E. Dale;
- Accili, Domenico;
- Goodyear, Laurie J.;
- Nair, K. Sreekumaran;
- Kahn, C. Ronald;
- Cai, Weikang
Publication type:
journal article
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway.
Published in:
Nature Immunology, 2004, v. 5, n. 4, p. 388, doi. 10.1038/ni1056
By:
- Flick, Leah M.;
- Park, Kiwon W.;
- Softic, Samir;
- Greer, Todd M.;
- Keledjian, Raquel;
- Yang, Rong;
- Uddin, Jasim;
- Guggino, William B.;
- Atabani, Sowsan F.;
- Belkaid, Yasmine;
- Xu, Yan;
- Whitsett, Jeffrey A.;
- Accurso, Frank J.;
- Wills-Karp, Marsha;
- Petasis, Nicos A.;
- Karp, Christopher L.
Publication type:
Article
Role of Dietary Fructose and Hepatic De Novo Lipogenesis in Fatty Liver Disease.
Published in:
2016
By:
- Softic, Samir;
- Cohen, David;
- Kahn, C.;
- Cohen, David E;
- Kahn, C Ronald
Publication type:
journal article
Risk-factors Associated With Poor Outcomes in VEO-IBD Secondary to XIAP Deficiency: A Case Report and Literature Review.
Published in:
2019
By:
- Lekbua, Asama;
- Ouahed, Jodie;
- O'Connell, Amy E.;
- Kahn, Stacy A.;
- Goldsmith, Jeffrey D.;
- Imamura, Toshihiko;
- Duncan, Christine N.;
- Kelsen, Judith R.;
- Worthey, Elizabeth;
- Snapper, Scott B.;
- Softic, Samir
Publication type:
journal article
Evolving Role for Pharmacotherapy in NAFLD/NASH.
Published in:
CTS: Clinical & Translational Science, 2021, v. 14, n. 1, p. 11, doi. 10.1111/cts.12839
By:
- Attia, Suzanna L.;
- Softic, Samir;
- Mouzaki, Marialena
Publication type:
Article
Fructose metabolism by the guts cuts liver fat.
Published in:
2020
By:
- Helsley, Robert N.;
- Softic, Samir
Publication type:
Letter
Temporal dynamics of liver mitochondrial protein acetylation and succinylation and metabolites due to high fat diet and/or excess glucose or fructose.
Published in:
PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208973
By:
- Meyer, Jesse G.;
- Softic, Samir;
- Basisty, Nathan;
- Rardin, Matthew J.;
- Verdin, Eric;
- Gibson, Bradford W.;
- Ilkayeva, Olga;
- Newgard, Christopher B.;
- Kahn, C. Ronald;
- Schilling, Birgit
Publication type:
Article
Fructose Metabolism and Metabolic Dysfunction in Adolescents and Young Adults.
Published in:
2023
By:
- Softic, Samir;
- Lanaspa, Miguel A.;
- DeBosch, Brian
Publication type:
Editorial
Dietary Counseling Aimed at Reducing Sugar Intake Yields the Greatest Improvement in Management of Weight and Metabolic Dysfunction in Children with Obesity.
Published in:
Nutrients, 2022, v. 14, n. 7, p. 1500, doi. 10.3390/nu14071500
By:
- Radulescu, Aurelia;
- Killian, Mary;
- Kang, Qiwen;
- Yuan, Qingcong;
- Softic, Samir
Publication type:
Article
Tissue-Specific Fructose Metabolism in Obesity and Diabetes.
Published in:
2020
By:
- Helsley, Robert N.;
- Moreau, Francois;
- Gupta, Manoj K.;
- Radulescu, Aurelia;
- DeBosch, Brian;
- Softic, Samir
Publication type:
journal article
Peripheral Insulin Regulates a Broad Network of Gene Expression in Hypothalamus, Hippocampus, and Nucleus Accumbens.
Published in:
2021
By:
- Cai, Weikang;
- Zhang, Xuemei;
- Batista, Thiago M.;
- García-Martín, Rubén;
- Softic, Samir;
- Wang, Guoxiao;
- Ramirez, Alfred K.;
- Konishi, Masahiro;
- O'Neill, Brian T.;
- Kim, Jong Hun;
- Kim, Jason K.;
- Kahn, C. Ronald
Publication type:
journal article
Muscle-Specific Insulin Receptor Overexpression Protects Mice From Diet-Induced Glucose Intolerance but Leads to Postreceptor Insulin Resistance.
Published in:
2020
By:
- Wang, Guoxiao;
- Yu, Yingying;
- Cai, Weikang;
- Batista, Thiago M.;
- Suk, Sujin;
- Noh, Hye Lim;
- Hirshman, Michael;
- Nigro, Pasquale;
- Li, Mengyao Ella;
- Softic, Samir;
- Goodyear, Laurie;
- Kim, Jason K.;
- Kahn, C. Ronald
Publication type:
journal article
1785-P: Mice with Muscle-Specific Insulin Receptor Overexpression Are Protected from Diet-Induced Obesity and Glucose Intolerance but Develop Post-Receptor Insulin Resistance.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1785-P
By:
- WANG, GUOXIAO;
- CAI, WEIKANG;
- BATISTA, THIAGO M.;
- SOFTIC, SAMIR;
- KAHN, C. RONALD
Publication type:
Article
Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.
Published in:
2016
By:
- Softic, Samir;
- Boucher, Jeremie;
- Solheim, Marie H.;
- Shiho Fujisaka;
- Haering, Max-Felix;
- Homan, Erica P.;
- Winnay, Jonathon;
- Perez-Atayde, Antonio R.;
- Kahn, C. Ronald;
- Fujisaka, Shiho
Publication type:
journal article
Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.
Published in:
2016
By:
- Boucher, Jeremie;
- Softic, Samir;
- El Ouaamari, Abdelfattah;
- Krumpoch, Megan T.;
- Kleinridders, Andre;
- Kulkarni, Rohit N.;
- O'Neill, Brian T.;
- Kahn, C. Ronald
Publication type:
journal article

Found: 22