Works by Socci, Nicholas D.

Results: 49
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    The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling.

    Published in:
    Nature Cell Biology, 2015, v. 17, n. 1, p. 81, doi. 10.1038/ncb3082
    By:
    • Okada, Tomoyo;
    • Sinha, Surajit;
    • Esposito, Ilaria;
    • Schiavon, Gaia;
    • López-Lago, Miguel A.;
    • Su, Wenjing;
    • Pratilas, Christine A.;
    • Abele, Cristina;
    • Hernandez, Jonathan M.;
    • Ohara, Masahiro;
    • Okada, Morihito;
    • Viale, Agnes;
    • Heguy, Adriana;
    • Socci, Nicholas D.;
    • Sapino, Anna;
    • Seshan, Venkatraman E.;
    • Long, Stephen;
    • Inghirami, Giorgio;
    • Rosen, Neal;
    • Giancotti, Filippo G.
    Publication type:
    Article
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    Tumor fraction-guided cell-free DNA profiling in metastatic solid tumor patients.

    Published in:
    Genome Medicine, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13073-021-00898-8
    By:
    • Tsui, Dana W. Y.;
    • Cheng, Michael L.;
    • Shady, Maha;
    • Yang, Julie L.;
    • Stephens, Dennis;
    • Won, Helen;
    • Srinivasan, Preethi;
    • Huberman, Kety;
    • Meng, Fanli;
    • Jing, Xiaohong;
    • Patel, Juber;
    • Hasan, Maysun;
    • Johnson, Ian;
    • Gedvilaite, Erika;
    • Houck-Loomis, Brian;
    • Socci, Nicholas D.;
    • Selcuklu, S. Duygu;
    • Seshan, Venkatraman E.;
    • Zhang, Hongxin;
    • Chakravarty, Debyani
    Publication type:
    Article
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    Chordoma and chondrosarcoma gene profile: implications for immunotherapy.

    Published in:
    Cancer Immunology, Immunotherapy, 2009, v. 58, n. 3, p. 339, doi. 10.1007/s00262-008-0557-7
    By:
    • Schwab, Joseph H.;
    • Boland, Patrick J.;
    • Agaram, Narasimhan P.;
    • Socci, Nicholas D.;
    • Tianhua Guo;
    • O'Toole, Gary C.;
    • Xinhui Wang;
    • Ostroumov, Elena;
    • Hunter, Christopher J.;
    • Block, Joel A.;
    • Doty, Stephen;
    • Ferrone, Soldano;
    • Healey, John H.;
    • Antonescu, Cristina R.
    Publication type:
    Article
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    Cancer-associated Histone H3 N-terminal arginine mutations disrupt PRC2 activity and impair differentiation.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49486-5
    By:
    • Nacev, Benjamin A.;
    • Dabas, Yakshi;
    • Paul, Matthew R.;
    • Pacheco, Christian;
    • Mitchener, Michelle;
    • Perez, Yekaterina;
    • Fang, Yan;
    • Soshnev, Alexey A.;
    • Barrows, Douglas;
    • Carroll, Thomas;
    • Socci, Nicholas D.;
    • St. Jean, Samantha C.;
    • Tiwari, Sagarika;
    • Gruss, Michael J.;
    • Monette, Sebastien;
    • Tap, William D.;
    • Garcia, Benjamin A.;
    • Muir, Tom;
    • Allis, C. David
    Publication type:
    Article
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    Optimization of Dosing for EGFR-Mutant Non-Small Cell Lung Cancer with Evolutionary Cancer Modeling.

    Published in:
    Science Translational Medicine, 2011, v. 3, n. 90, p. 1, doi. 10.1126/scitranslmed.3002356
    By:
    • Chmielecki, Juliann;
    • Jasmine Foo;
    • Oxnard, Geoffrey R.;
    • Hutchinson, Katherine;
    • Ohashi, Kadoaki;
    • Somwar, Romel;
    • Lu Wang;
    • Amato, Katherine R.;
    • Arcila, Maria;
    • Sos, Martin L.;
    • Socci, Nicholas D.;
    • Viale, Agnes;
    • de Stanchina, Elisa;
    • Ginsberg, Michelle S.;
    • Thomas, Roman K.;
    • Kris, Mark G.;
    • Inoue, Akira;
    • Ladanyi, Marc;
    • Miller, Vincent A.;
    • Michor, Franziska
    Publication type:
    Article
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    Response to Zhou and Robinson.

    Published in:
    Genome Biology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s13059-015-0782-2
    By:
    • Betel, Doron;
    • Socci, Nicholas D.;
    • Khanin, Raya;
    • Mason, Christopher E.;
    • Rapaport, Franck
    Publication type:
    Article
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    Genomic and Transcriptomic Characterization of Papillary Microcarcinomas With Lateral Neck Lymph Node Metastases.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2019, v. 104, n. 10, p. 4889, doi. 10.1210/jc.2019-00431
    By:
    • Perera, Dilmi;
    • Ghossein, Ronald;
    • Camacho, Niedzica;
    • Senbabaoglu, Yasin;
    • Seshan, Venkatraman;
    • Juan Li;
    • Bouvier, Nancy;
    • Boucai, Laura;
    • Viale, Agnes;
    • Socci, Nicholas D.;
    • Untch, Brian R.;
    • Gonen, Mithat;
    • Knauf, Jeffrey;
    • Fagin, James A.;
    • Berger, Michael;
    • Tuttle, R. Michael
    Publication type:
    Article
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    Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis.

    Published in:
    BMC Cancer, 2009, v. 9, p. 1, doi. 10.1186/1471-2407-9-11
    By:
    • Estilo, Cherry L.;
    • O-charoenrat, Pornchai;
    • Talbot, Simon;
    • Socci, Nicholas D.;
    • Carlson, Diane L.;
    • Ghossein, Ronald;
    • Williams, Tijaana;
    • Yonekawa, Yoshihiro;
    • Ramanathan, Yegnanarayana;
    • Boyle, Jay O.;
    • Kraus, Dennis H.;
    • Patel, Snehal;
    • Shaha, Ashok R.;
    • Wong, Richard J.;
    • Huryn, Joseph M.;
    • Shah, Jatin P.;
    • Singh, Bhuvanesh
    Publication type:
    Article
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    Systematic screen for tyrosine kinase rearrangements identifies a novel C6orf204-PDGFRB fusion in a patient with recurrent T-ALL and an associated myeloproliferative neoplasm.

    Published in:
    Genes, Chromosomes & Cancer, 2012, v. 51, n. 1, p. 54, doi. 10.1002/gcc.20930
    By:
    • Chmielecki, Juliann;
    • Peifer, Martin;
    • Viale, Agnes;
    • Hutchinson, Katherine;
    • Giltnane, Jennifer;
    • Socci, Nicholas D.;
    • Hollis, Clayton J.;
    • Dean, Rebecca S.;
    • Yenamandra, Ashwini;
    • Jagasia, Madan;
    • Kim, Annette S.;
    • Davé, Utpal P.;
    • Thomas, Roman K.;
    • Pao, William
    Publication type:
    Article
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    Inducible in vivo genome editing with CRISPR-Cas9.

    Published in:
    Nature Biotechnology, 2015, v. 33, n. 4, p. 390, doi. 10.1038/nbt.3155
    By:
    • Dow, Lukas E;
    • Fisher, Jonathan;
    • O'Rourke, Kevin P;
    • Muley, Ashlesha;
    • Kastenhuber, Edward R;
    • Livshits, Geulah;
    • Tschaharganeh, Darjus F;
    • Socci, Nicholas D;
    • Lowe, Scott W
    Publication type:
    Article
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    A microglia clonal inflammatory disorder in Alzheimer's disease.

    Published in:
    eLife, 2025, p. 1, doi. 10.7554/eLife.96519
    By:
    • Vicario, Rocio;
    • Fragkogianni, Stamatina;
    • Weber, Leslie;
    • Lazarov, Tomi;
    • Yang Hu;
    • Hayashi, Samantha Y.;
    • Craddock, Barbara;
    • Socci, Nicholas D.;
    • Alberdi, Araitz;
    • Baako, Ann;
    • Ay, Oyku;
    • Ogishi, Masato;
    • Lopez-Rodrigo, Estibaliz;
    • Kappagantula, Rajya;
    • Viale, Agnes;
    • Iacobuzio-Donahue, Christine A.;
    • Ting Zhou;
    • Ransohoff, Richard M.;
    • Chesworth, Richard;
    • Abdel-Wahab, Omar
    Publication type:
    Article
    32

    ACK1 and BRK non-receptor tyrosine kinase deficiencies are associated with familial systemic lupus and involved in efferocytosis.

    Published in:
    eLife, 2024, p. 1, doi. 10.7554/eLife.96085
    By:
    • Guillet, Stephanie;
    • Lazarov, Tomi;
    • Jordan, Natasha;
    • Boisson, Bertrand;
    • Tello, Maria;
    • Craddock, Barbara;
    • Ting Zhou;
    • Nishi, Chihiro;
    • Bareja, Rohan;
    • Yang, Hairu;
    • Rieux Laucat, Frederic;
    • Fregel Lorenzo, Rosa Irene;
    • Dyall, Sabrina D.;
    • Isenberg, David;
    • D'Cruz, David;
    • Lachmann, Nico;
    • Elemento, Olivier;
    • Viale, Agnes;
    • Socci, Nicholas D.;
    • Abel, Laurent
    Publication type:
    Article
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    Functional Copy-Number Alterations in Cancer.

    Published in:
    PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003179
    By:
    • Taylor, Barry S.;
    • Barretina, Jordi;
    • Socci, Nicholas D.;
    • DeCarolis, Penelope;
    • Ladanyi, Marc;
    • Meyerson, Matthew;
    • Singer, Samuel;
    • Sander, Chris
    Publication type:
    Article
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    Forward genetic screen of human transposase genomic rearrangements.

    Published in:
    BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2877-x
    By:
    • Henssen, Anton G.;
    • Jiang, Eileen;
    • Jiali Zhuang;
    • Pinello, Luca;
    • Socci, Nicholas D.;
    • Koche, Richard;
    • Gonen, Mithat;
    • Villasante, Camila M.;
    • Armstrong, Scott A.;
    • Bauer, Daniel E.;
    • Zhiping Weng;
    • Kentsis, Alex
    Publication type:
    Article
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    Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30453-x
    By:
    • Nacev, Benjamin A.;
    • Sanchez-Vega, Francisco;
    • Smith, Shaleigh A.;
    • Antonescu, Cristina R.;
    • Rosenbaum, Evan;
    • Shi, Hongyu;
    • Tang, Cerise;
    • Socci, Nicholas D.;
    • Rana, Satshil;
    • Gularte-Mérida, Rodrigo;
    • Zehir, Ahmet;
    • Gounder, Mrinal M.;
    • Bowler, Timothy G.;
    • Luthra, Anisha;
    • Jadeja, Bhumika;
    • Okada, Azusa;
    • Strong, Jonathan A.;
    • Stoller, Jake;
    • Chan, Jason E.;
    • Chi, Ping
    Publication type:
    Article
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    Clinical sequencing of soft tissue and bone sarcomas delineates diverse genomic landscapes and potential therapeutic targets.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-30453-x
    By:
    • Nacev, Benjamin A.;
    • Sanchez-Vega, Francisco;
    • Smith, Shaleigh A.;
    • Antonescu, Cristina R.;
    • Rosenbaum, Evan;
    • Shi, Hongyu;
    • Tang, Cerise;
    • Socci, Nicholas D.;
    • Rana, Satshil;
    • Gularte-Mérida, Rodrigo;
    • Zehir, Ahmet;
    • Gounder, Mrinal M.;
    • Bowler, Timothy G.;
    • Luthra, Anisha;
    • Jadeja, Bhumika;
    • Okada, Azusa;
    • Strong, Jonathan A.;
    • Stoller, Jake;
    • Chan, Jason E.;
    • Chi, Ping
    Publication type:
    Article
    40

    A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations.

    Published in:
    Nature Genetics, 2014, v. 46, n. 6, p. 595, doi. 10.1038/ng.2969
    By:
    • Kohsaka, Shinji;
    • Shukla, Neerav;
    • Ameur, Nabahet;
    • Ito, Tatsuo;
    • Ng, Charlotte K Y;
    • Wang, Lu;
    • Lim, Diana;
    • Marchetti, Angela;
    • Viale, Agnes;
    • Pirun, Mono;
    • Socci, Nicholas D;
    • Qin, Li-Xuan;
    • Sciot, Raf;
    • Bridge, Julia;
    • Singer, Samuel;
    • Meyers, Paul;
    • Wexler, Leonard H;
    • Barr, Frederic G;
    • Dogan, Snjezana;
    • Fletcher, Jonathan A
    Publication type:
    Article
    41

    Germline mutations in BAP1 predispose to melanocytic tumors.

    Published in:
    Nature Genetics, 2011, v. 43, n. 10, p. 1018, doi. 10.1038/ng.910
    By:
    • Wiesner, Thomas;
    • Obenauf, Anna C;
    • Murali, Rajmohan;
    • Fried, Isabella;
    • Griewank, Klaus G;
    • Ulz, Peter;
    • Windpassinger, Christian;
    • Wackernagel, Werner;
    • Loy, Shea;
    • Wolf, Ingrid;
    • Viale, Agnes;
    • Lash, Alex E;
    • Pirun, Mono;
    • Socci, Nicholas D;
    • Rütten, Arno;
    • Palmedo, Gabriele;
    • Abramson, David;
    • Offit, Kenneth;
    • Ott, Arthur;
    • Becker, Jürgen C
    Publication type:
    Article
    42

    Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.

    Published in:
    Nature Genetics, 2010, v. 42, n. 8, p. 715, doi. 10.1038/ng.619
    By:
    • Barretina, Jordi;
    • Taylor, Barry S.;
    • Banerji, Shantanu;
    • Ramos, Alexis H.;
    • Lagos-Quintana, Mariana;
    • DeCarolis, Penelope L.;
    • Shah, Kinjal;
    • Socci, Nicholas D.;
    • Weir, Barbara A.;
    • Ho, Alan;
    • Chiang, Derek Y.;
    • Reva, Boris;
    • Mermel, Craig H.;
    • Getz, Gad;
    • Antipin, Yevgenyi;
    • Beroukhim, Rameen;
    • Major, John E.;
    • Hatton, Charles;
    • Nicoletti, Richard;
    • Hanna, Megan
    Publication type:
    Article
    43

    Identification of DOK genes as lung tumor suppressors.

    Published in:
    Nature Genetics, 2010, v. 42, n. 3, p. 216, doi. 10.1038/ng.527
    By:
    • Berger, Alice H.;
    • Niki, Masaru;
    • Morotti, Alessandro;
    • Taylor, Barry S.;
    • Socci, Nicholas D.;
    • Viale, Agnes;
    • Brennan, Cameron;
    • Szoke, Janos;
    • Motoi, Noriko;
    • Rothman, Paul B.;
    • Teruya-Feldstein, Julie;
    • Gerald, William L.;
    • Ladanyi, Marc;
    • Pandolfi, Pier Paolo
    Publication type:
    Article
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    Genomic and transcriptomic analysis of a library of small cell lung cancer patient-derived xenografts.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29794-4
    By:
    • Caeser, Rebecca;
    • Egger, Jacklynn V.;
    • Chavan, Shweta;
    • Socci, Nicholas D.;
    • Jones, Caitlin Byrne;
    • Kombak, Faruk Erdem;
    • Asher, Marina;
    • Roehrl, Michael H.;
    • Shah, Nisargbhai S.;
    • Allaj, Viola;
    • Manoj, Parvathy;
    • Tischfield, Sam E.;
    • Kulick, Amanda;
    • Meneses, Maximiliano;
    • Iacobuzio-Donahue, Christine A.;
    • Lai, W. Victoria;
    • Bhanot, Umeshkumar;
    • Baine, Marina K.;
    • Rekhtman, Natasha;
    • Hollmann, Travis J.
    Publication type:
    Article
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