Works by Sobota, Radoslaw M.

Results: 30

Serial proteomic and metabolomic profiling for early neuroprognostication after out-of-hospital cardiac arrest: a prospective observational study.

Published in:

2025

By:

Liu, Xinyi;
Woo, Kai Lee;
Chen, Liyan;
Pakkiri, Leroy Sivappiragasam;
Lim, Rachel Liyu;
Ong, Marcus E.H.;
Torta, Federico;
M. Sobota, Radoslaw;
Choi, Hyungwon;
Richards, A. Mark;
Drum, Chester Lee;
Lim, Shir Lynn

Publication type:

Letter

Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.90762

By:

Bing Liang Alvin Chew;
AN Qi Ngoh;
Wint Wint Phoo;
Kitti Wing Ki Chan;
Zheng Ser;
Tulsian, Nikhil K.;
Shiao See Lim;
Mei Jie Grace Weng;
Satoru Watanabe;
Choy, Milly M.;
Low, Jenny;
Ooi, Eng Eong;
Ruedl, Christiane;
Sobota, Radoslaw M.;
Vasudevan, Subhash G.;
Dahai Luo

Publication type:

Article

DUSP6 regulates Notch1 signalling in colorectal cancer.

Published in:

Nature Communications, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41467-024-54383-y

By:

Png, Chin Wen;
Weerasooriya, Madhushanee;
Li, Heng;
Hou, Xiaowen;
Teo, Fiona Yayuan;
Huang, Shiying;
Ser, Zheng;
Weng, Franklin Yau Kok;
Rethnam, Malini;
Chia, Gloryn;
Sobota, Radoslaw M.;
Chong, Choon Seng;
Tan, Ker-Kan;
Zhang, Yongliang

Publication type:

Article

TDP43 aggregation at ER-exit sites impairs ER-to-Golgi transport.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52706-7

By:

Wu, Hongyi;
Wang, Loo Chien;
Sow, Belle M.;
Leow, Damien;
Zhu, Jin;
Gallo, Kathryn M.;
Wilsbach, Kathleen;
Gupta, Roshni;
Ostrow, Lyle W.;
Yeo, Crystal J. J.;
Sobota, Radoslaw M.;
Li, Rong

Publication type:

Article

Dynamic Interactions of Post Cleaved NS2B Cofactor and NS3 Protease Identified by Integrative Structural Approaches.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/v14071440

By:

Quek, Jun-Ping;
Ser, Zheng;
Chew, Bing Liang Alvin;
Li, Xin;
Wang, Lili;
Sobota, Radoslaw M.;
Luo, Dahai;
Phoo, Wint Wint

Publication type:

Article

Occlusion of TCR binding to HLA-A*11:01 by a non-pathogenic human alloantibody.

Published in:

Cellular & Molecular Life Sciences, 2025, v. 82, n. 1, p. 1, doi. 10.1007/s00018-025-05614-y

By:

Hamidinia, Maryam;
Gu, Yue;
Ser, Zheng;
Brzostek, Joanna;
Tay, Neil Q.;
Yap, Jiawei;
Chua, Yen Leong;
Lim, Yan Ting;
Wood, Kathryn J.;
Vathsala, Anantharaman;
Sobota, Radoslaw M.;
MacAry, Paul A.;
Gascoigne, Nicholas R. J.

Publication type:

Article

Detection of Bacterial Neutral Ceramidase in Diabetic Foot Ulcers with an Optimized Substrate and Chemoenzymatic Probes.

Published in:

Angewandte Chemie, 2023, v. 135, n. 33, p. 1, doi. 10.1002/ange.202307553

By:

Zou, Jiao Xia;
Chua, Wisely;
Ser, Zheng;
Wang, Shi Mei;
Chiang, Grace Shu Hui;
Sanmugam, Kavitha;
Tan, Boon Yeow;
Sobota, Radoslaw M.;
Li, Hao

Publication type:

Article

The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31176-9

By:

Atwal, Sharanjeet;
Wongsantichon, Jantana;
Giengkam, Suparat;
Saharat, Kittirat;
Pittayasathornthun, Yanin Jaiyen;
Chuenklin, Suthida;
Wang, Loo Chien;
Chung, Taerin;
Huh, Hyun;
Lee, Sang-Hyuk;
Sobota, Radoslaw M.;
Salje, Jeanne

Publication type:

Article

The obligate intracellular bacterium Orientia tsutsugamushi differentiates into a developmentally distinct extracellular state.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31176-9

By:

Atwal, Sharanjeet;
Wongsantichon, Jantana;
Giengkam, Suparat;
Saharat, Kittirat;
Pittayasathornthun, Yanin Jaiyen;
Chuenklin, Suthida;
Wang, Loo Chien;
Chung, Taerin;
Huh, Hyun;
Lee, Sang-Hyuk;
Sobota, Radoslaw M.;
Salje, Jeanne

Publication type:

Article

KOPI: Kinase inhibitOr Proteome Impact analysis.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16557-w

By:

Li, Ginny Xiaohe;
Zhao, Tianyun;
Wang, Loo Chien;
Choi, Hyungwon;
Lim, Yan Ting;
Sobota, Radoslaw M.

Publication type:

Article

Dendritic cell derived IL-2 inhibits survival of terminally mature cells via an autocrine signaling pathway.

Published in:

European Journal of Immunology, 2015, v. 45, n. 5, p. 1494, doi. 10.1002/eji.201445050

By:

Balachander, Akhila;
Nabti, Sabrina;
Sobota, Radoslaw M.;
Foo, Shihui;
Zolezzi, Francesca;
Lee, Bernett T. K.;
Poidinger, Michael;
Ricciardi‐Castagnoli, Paola

Publication type:

Article

Proteome integral solubility alteration via label‐free DIA approach (PISA‐DIA), game changer in drug target deconvolution.

Published in:

Proteomics, 2025, v. 25, n. 3, p. 1, doi. 10.1002/pmic.202400147

By:

Ser, Zheng;
Sobota, Radoslaw M.

Publication type:

Article

Fungus-derived protein particles as cell-adhesive matrices for cell-cultivated food.

Published in:

NPJ Science of Food, 2023, v. 7, n. 1, p. 1, doi. 10.1038/s41538-023-00209-y

By:

Teo, Yu Xing;
Lee, Kah Yin;
Goh, Corinna Jie Hui;
Wang, Loo Chien;
Sobota, Radoslaw M.;
Chiam, Keng-Hwee;
Du, Chan;
Wan, Andrew C. A.

Publication type:

Article

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38132-1

By:

Zhang, Jieqiong;
Hu, Zhenhua;
Chung, Hwa Hwa;
Tian, Yun;
Lau, Kah Weng;
Ser, Zheng;
Lim, Yan Ting;
Sobota, Radoslaw M.;
Leong, Hwei Fen;
Chen, Benjamin Jieming;
Yeo, Clarisse Jingyi;
Tan, Shawn Ying Xuan;
Kang, Jian;
Tan, Dennis Eng Kiat;
Sou, Ieng Fong;
McClurg, Urszula Lucja;
Lakshmanan, Manikandan;
Vaiyapuri, Thamil Selvan;
Raju, Anandhkumar;
Wong, Esther Sook Miin

Publication type:

Article

Cellular thermal shift assay for the identification of drug–target interactions in the Plasmodium falciparum proteome.

Published in:

Nature Protocols, 2020, v. 15, n. 6, p. 1881, doi. 10.1038/s41596-020-0310-z

By:

Dziekan, Jerzy Michal;
Wirjanata, Grennady;
Dai, Lingyun;
Go, Ka Diam;
Yu, Han;
Lim, Yan Ting;
Chen, Liyan;
Wang, Loo Chien;
Puspita, Brenda;
Prabhu, Nayana;
Sobota, Radoslaw M.;
Nordlund, Pär;
Bozdech, Zbynek

Publication type:

Article

Detection of Bacterial Neutral Ceramidase in Diabetic Foot Ulcers with an Optimized Substrate and Chemoenzymatic Probes.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 33, p. 1, doi. 10.1002/anie.202307553

By:

Zou, Jiao Xia;
Chua, Wisely;
Ser, Zheng;
Wang, Shi Mei;
Chiang, Grace Shu Hui;
Sanmugam, Kavitha;
Tan, Boon Yeow;
Sobota, Radoslaw M.;
Li, Hao

Publication type:

Article

Structural basis of peptide secretion for Quorum sensing by ComA.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-42852-9

By:

Yu, Lin;
Xu, Xin;
Chua, Wan-Zhen;
Feng, Hao;
Ser, Zheng;
Shao, Kai;
Shi, Jian;
Wang, Yumei;
Li, Zongli;
Sobota, Radoslaw M.;
Sham, Lok-To;
Luo, Min

Publication type:

Article

Metabolomics profiling in multi-ancestral individuals with type 2 diabetes in Singapore identified metabolites associated with renal function decline.

Published in:

Diabetologia, 2025, v. 68, n. 3, p. 557, doi. 10.1007/s00125-024-06324-z

By:

Chen, Yuqing;
Torta, Federico;
Koh, Hiromi W. L.;
Benke, Peter I.;
Gurung, Resham L.;
Liu, Jian-Jun;
Ang, Keven;
Shao, Yi-Ming;
Chan, Gek Cher;
Choo, Jason Chon-Jun;
Ching, Jianhong;
Kovalik, Jean-Paul;
Kalhan, Tosha;
Dorajoo, Rajkumar;
Khor, Chiea Chuen;
Li, Yun;
Tang, Wern Ee;
Seah, Darren E. J.;
Sabanayagam, Charumathi;
Sobota, Radoslaw M.

Publication type:

Article

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes.

Published in:

Nature Communications, 2015, v. 6, n. 10, p. 8761, doi. 10.1038/ncomms9761

By:

Viganò, Elena;
Diamond, Catherine Emma;
Spreafico, Roberto;
Balachander, Akhila;
Sobota, Radoslaw M.;
Mortellaro, Alessandra

Publication type:

Article

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0208273

By:

Lim, Yan Ting;
Prabhu, Nayana;
Dai, Lingyun;
Go, Ka Diam;
Chen, Dan;
Sreekumar, Lekshmy;
Egeblad, Louise;
Eriksson, Staffan;
Chen, Liyan;
Veerappan, Saranya;
Teo, Hsiang Ling;
Tan, Chris Soon Heng;
Lengqvist, Johan;
Larsson, Andreas;
Sobota, Radoslaw M.;
Nordlund, Pär

Publication type:

Article

SH3TC2, a protein mutant in Charcot–Marie–Tooth neuropathy, links peripheral nerve myelination to endosomal recycling.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 8, p. 2462, doi. 10.1093/brain/awq168

By:

Stendel, Claudia;
Roos, Andreas;
Kleine, Henning;
Arnaud, Estelle;
Özçelik, Murat;
Sidiropoulos, Páris N. M.;
Zenker, Jennifer;
Schüpfer, Fanny;
Lehmann, Ute;
Sobota, Radoslaw M.;
Litchfield, David W.;
Lüscher, Bernhard;
Chrast, Roman;
Suter, Ueli;
Senderek, Jan

Publication type:

Article

Complete Sequences of the Velvet Worm Slime Proteins Reveal that Slime Formation is Enabled by Disulfide Bonds and Intrinsically Disordered Regions.

Published in:

Advanced Science, 2022, v. 9, n. 18, p. 1, doi. 10.1002/advs.202201444

By:

Lu, Yang;
Sharma, Bhargy;
Soon, Wei Long;
Shi, Xiangyan;
Zhao, Tianyun;
Lim, Yan Ting;
Sobota, Radoslaw M.;
Hoon, Shawn;
Pilloni, Giovanni;
Usadi, Adam;
Pervushin, Konstantin;
Miserez, Ali

Publication type:

Article

Squid Suckerin‐Spider Silk Fusion Protein Hydrogel for Delivery of Mesenchymal Stem Cell Secretome to Chronic Wounds.

Published in:

Advanced Healthcare Materials, 2023, v. 12, n. 1, p. 1, doi. 10.1002/adhm.202201900

By:

Koh, Kenrick;
Wang, Jun Kit;
Chen, James Xiao Yuan;
Hiew, Shu Hui;
Cheng, Hong Sheng;
Gabryelczyk, Bartosz;
Vos, Marcus Ivan Gerard;
Yip, Yun Sheng;
Chen, Liyan;
Sobota, Radoslaw M.;
Chua, Damian Kang Keat;
Tan, Nguan Soon;
Tay, Chor Yong;
Miserez, Ali

Publication type:

Article

Dual RNA-seq of Orientia tsutsugamushi informs on host-pathogen interactions for this neglected intracellular human pathogen.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17094-8

By:

Mika-Gospodorz, Bozena;
Giengkam, Suparat;
Westermann, Alexander J.;
Wongsantichon, Jantana;
Kion-Crosby, Willow;
Chuenklin, Suthida;
Wang, Loo Chien;
Sunyakumthorn, Piyanate;
Sobota, Radoslaw M.;
Subbian, Selvakumar;
Vogel, Jörg;
Barquist, Lars;
Salje, Jeanne

Publication type:

Article

Mitochondrial peptide BRAWNIN is essential for vertebrate respiratory complex III assembly.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14999-2

By:

Zhang, Shan;
Reljić, Boris;
Liang, Chao;
Kerouanton, Baptiste;
Francisco, Joel Celio;
Peh, Jih Hou;
Mary, Camille;
Jagannathan, Narendra Suhas;
Olexiouk, Volodimir;
Tang, Claire;
Fidelito, Gio;
Nama, Srikanth;
Cheng, Ruey-Kuang;
Wee, Caroline Lei;
Wang, Loo Chien;
Duek Roggli, Paula;
Sampath, Prabha;
Lane, Lydie;
Petretto, Enrico;
Sobota, Radoslaw M.

Publication type:

Article

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay.

Published in:

Science Translational Medicine, 2019, v. 11, n. 473, p. N.PAG, doi. 10.1126/scitranslmed.aau3174

By:

Dziekan, Jerzy M.;
Yu, Han;
Chen, Dan;
Dai, Lingyun;
Wirjanata, Grennady;
Larsson, Andreas;
Prabhu, Nayana;
Sobota, Radoslaw M.;
Bozdech, Zbynek;
Nordlund, Pär

Publication type:

Article

Author Correction: METTL8 links mt-tRNA m<sup>3</sup>C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity.

Published in:

2024

By:

Lee, Bernice Woon Li;
Chuah, You Heng;
Yoon, Jeehyun;
Grinchuk, Oleg V.;
Liang, Yajing;
Hirpara, Jayshree L.;
Shen, Yating;
Wang, Loo Chien;
Lim, Yan Ting;
Zhao, Tianyun;
Sobota, Radoslaw M.;
Yeo, Tseng Tsai;
Wong, Andrea Li Ann;
Teo, Kejia;
Nga, Vincent Diong Weng;
Tan, Bryce Wei Quan;
Suda, Toshio;
Toh, Tan Boon;
Pervaiz, Shazib;
Lin, Zhewang

Publication type:

Correction Notice

METTL8 links mt-tRNA m<sup>3</sup>C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity.

Published in:

Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06718-2

By:

Lee, Bernice Woon Li;
Chuah, You Heng;
Yoon, Jeehyun;
Grinchuk, Oleg V.;
Liang, Yajing;
Hirpara, Jayshree L.;
Shen, Yating;
Wang, Loo Chien;
Lim, Yan Ting;
Zhao, Tianyun;
Sobota, Radoslaw M.;
Yeo, Tseng Tsai;
Wong, Andrea Li Ann;
Teo, Kejia;
Nga, Vincent Diong Weng;
Tan, Bryce Wei Quan;
Suda, Toshio;
Toh, Tan Boon;
Pervaiz, Shazib;
Lin, Zhewang

Publication type:

Article

Unveiling the Influence of Tumor Microenvironment and Spatial Heterogeneity on Temozolomide Resistance in Glioblastoma Using an Advanced Human In Vitro Model of the Blood‐Brain Barrier and Glioblastoma (Small 52/2023).

Published in:

Small, 2023, v. 19, n. 52, p. 1, doi. 10.1002/smll.202370436

By:

Lam, Maxine SY;
Aw, Joey JY;
Tan, Damien;
Vijayakumar, Ragavi;
Lim, Hui Yi Grace;
Yada, Swathi;
Pang, Qing You;
Barker, Nick;
Tang, Carol;
Ang, Beng Ti;
Sobota, Radoslaw M.;
Pavesi, Andrea

Publication type:

Article

Unveiling the Influence of Tumor Microenvironment and Spatial Heterogeneity on Temozolomide Resistance in Glioblastoma Using an Advanced Human In Vitro Model of the Blood‐Brain Barrier and Glioblastoma.

Published in:

Small, 2023, v. 19, n. 52, p. 1, doi. 10.1002/smll.202302280

By:

Lam, Maxine SY;
Aw, Joey JY;
Tan, Damien;
Vijayakumar, Ragavi;
Lim, Hui Yi Grace;
Yada, Swathi;
Pang, Qing You;
Barker, Nick;
Tang, Carol;
Ang, Beng Ti;
Sobota, Radoslaw M.;
Pavesi, Andrea

Publication type:

Article