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A germline mutation at the extreme 3′ end of the APC gene results in a severe desmoid phenotype and is associated with overexpression of beta-catenin in the desmoid tumor.
- Published in:
- Clinical Genetics, 2000, v. 57, n. 3, p. 205, doi. 10.1034/j.1399-0004.2000.570306.x
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- Publication type:
- Article
Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron.
- Published in:
- eLife, 2015, p. 1, doi. 10.7554/eLife.04000.001
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- Publication type:
- Article
HOXA13 in etiology and oncogenic potential of Barrett's esophagus.
- Published in:
- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23641-8
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- Publication type:
- Article
Issues with RNF43 antibodies to reliably detect intracellular location.
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- PLoS ONE, 2023, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0283894
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- Publication type:
- Article
Apc modulates embryonic stem-cell differentiation by controlling the dosage of β-catenin signaling.
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- Nature Genetics, 2002, v. 32, n. 4, p. 594, doi. 10.1038/ng1045
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- Article
Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV.
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- Scientific Reports, 2016, p. 25482, doi. 10.1038/srep25482
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- Publication type:
- Article
SOX2 redirects the developmental fate of the intestinal epithelium toward a premature gastric phenotype.
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- Journal of Molecular Cell Biology, 2012, v. 4, n. 6, p. 377, doi. 10.1093/jmcb/mjs030
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- Publication type:
- Article
Cancer Stemness in <i>Apc</i>- vs. <i>Apc</i>/<i>KRAS</i>-Driven Intestinal Tumorigenesis.
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- PLoS ONE, 2013, v. 8, n. 9, p. 1, doi. 10.1371/journal.pone.0073872
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- Publication type:
- Article
Wnt/β-Catenin Signaling in Liver Cancers.
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- Cancers, 2019, v. 11, n. 7, p. 926, doi. 10.3390/cancers11070926
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- Publication type:
- Article
Marfan-like habitus and familial adenomatous polyposis in two unrelated males: a significant association?
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- European Journal of Human Genetics, 1999, v. 7, n. 5, p. 609, doi. 10.1038/sj.ejhg.5200350
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- Publication type:
- Article
Sox2 Regulates the Emergence of Lung Basal Cells by Directly Activating the Transcription of Trp63.
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- American Journal of Respiratory Cell & Molecular Biology, 2014, v. 51, n. 2, p. 311, doi. 10.1165/rcmb.2013-0419OC
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- Publication type:
- Article
The biological process of lysine‐tRNA charging is therapeutically targetable in liver cancer.
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- Liver International, 2021, v. 41, n. 1, p. 206, doi. 10.1111/liv.14692
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- Publication type:
- Article
Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-63741-x
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- Publication type:
- Article
Mutations in the APC tumour suppressor gene cause chromosomal instability.
- Published in:
- Nature Cell Biology, 2001, v. 3, n. 4, p. 433, doi. 10.1038/35070129
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- Publication type:
- Article
Cyclooxygenase-two (COX-2) modulates proliferation in aggressive fibromatosis (desmoid tumor).
- Published in:
- Oncogene, 2001, v. 20, n. 4, p. 451, doi. 10.1038/sj.onc.1204107
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- Publication type:
- Article
HOXA9 mediates and marks premalignant compartment size expansion in colonic adenomas.
- Published in:
- Carcinogenesis, 2019, v. 40, n. 12, p. 1514, doi. 10.1093/carcin/bgz038
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- Publication type:
- Article
Modeling liver cancer and therapy responsiveness using organoids derived from primary mouse liver tumors.
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- Carcinogenesis, 2019, v. 40, n. 1, p. 145, doi. 10.1093/carcin/bgy129
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- Publication type:
- Article
Wnt5a promotes human colon cancer cell migration and invasion but does not augment intestinal tumorigenesis in Apc1638N mice.
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- Carcinogenesis, 2013, v. 34, n. 11, p. 2629, doi. 10.1093/carcin/bgt215
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- Publication type:
- Article
A new conditional Apc-mutant mouse model for colorectal cancer.
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- Carcinogenesis, 2010, v. 31, n. 5, p. 946, doi. 10.1093/carcin/bgq046
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- Publication type:
- Article
Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines.
- Published in:
- PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0304607
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- Publication type:
- Article
Expression analysis of proline rich 15 ( Prr15) in mouse and human gastrointestinal tumors.
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- Molecular Carcinogenesis, 2011, v. 50, n. 1, p. 8, doi. 10.1002/mc.20692
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- Publication type:
- Article
Evaluation of AXIN1 and AXIN2 as targets of tankyrase inhibition in hepatocellular carcinoma cell lines.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87091-4
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- Publication type:
- Article
Activated Signaling Pathways and Targeted Therapies in Desmoid-Type Fibromatosis: A Literature Review.
- Published in:
- Frontiers in Oncology, 2019, p. N.PAG, doi. 10.3389/fonc.2019.00397
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- Publication type:
- Article
Targeted deletion of the C-terminus of the mouse adenomatous polyposis coli tumor suppressor results in neurologic phenotypes related to schizophrenia.
- Published in:
- Molecular Brain, 2014, v. 7, n. 1, p. 21, doi. 10.1186/1756-6606-7-21
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- Publication type:
- Article
A novel tissue-based ß-catenin gene and immunohistochemical analysis to exclude familial adenomatous polyposis among children with hepatoblastoma tumors.
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- 2018
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- Publication type:
- journal article
GNAS is not involved in gastrointestinal tumour formation in Peutz-Jeghers syndrome.
- Published in:
- 2013
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- Publication type:
- Letter
Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability.
- Published in:
- Genes, Chromosomes & Cancer, 2010, v. 49, n. 8, p. 746, doi. 10.1002/gcc.20786
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- Publication type:
- Article
Premature chromosome condensation revisited: A novel chemical approach permits efficient cytogenetic analysis of cancers.
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- Genes, Chromosomes & Cancer, 2003, v. 38, n. 2, p. 177, doi. 10.1002/gcc.10268
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- Publication type:
- Article
Serrated adenomas and mixed polyposis caused by a splice acceptor deletion in the mouse Smad4 gene.
- Published in:
- Genes, Chromosomes & Cancer, 2003, v. 36, n. 3, p. 273, doi. 10.1002/gcc.10169
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- Publication type:
- Article
A 10-Mb paracentric inversion of chromosome arm 2p inactivates MSH2 and is responsible for hereditary nonpolyposis colorectal cancer in a North-American kindred.
- Published in:
- Genes, Chromosomes & Cancer, 2002, v. 35, n. 1, p. 49, doi. 10.1002/gcc.10094
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- Publication type:
- Article
Somatic Apc mutations are selected upon their capacity to inactivate the β-catenin downregulating activity.
- Published in:
- Genes, Chromosomes & Cancer, 2000, v. 29, n. 3, p. 229, doi. 10.1002/1098-2264(2000)9999:9999<::AID-GCC1033>3.0.CO;2-R
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- Publication type:
- Article
The genetic background modifies the spontaneous and X-ray-induced tumor spectrum in the Apc1638N mouse model.
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- Genes, Chromosomes & Cancer, 1999, v. 24, n. 3, p. 191, doi. 10.1002/(SICI)1098-2264(199903)24:3<191::AID-GCC3>3.0.CO;2-L
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- Publication type:
- Article
Aberrant SOX2 expression in colorectal cancers does not correlate with mucinous differentiation and gastric mucin MUC5AC expression.
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- Virchows Archiv: European Journal of Pathology, 2014, v. 465, n. 4, p. 395, doi. 10.1007/s00428-014-1638-y
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- Publication type:
- Article
Disturbed balance between SOX2 and CDX2 in human vitelline duct anomalies and intestinal duplications.
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- Virchows Archiv: European Journal of Pathology, 2013, v. 462, n. 5, p. 515, doi. 10.1007/s00428-013-1405-5
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- Publication type:
- Article
Guanylin and uroguanylin are produced by mouse intestinal epithelial cells of columnar and secretory lineage.
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- Histochemistry & Cell Biology, 2016, v. 146, n. 4, p. 445, doi. 10.1007/s00418-016-1453-4
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- Publication type:
- Article
Restriction of intestinal stem cell expansion and the regenerative response by YAP.
- Published in:
- Nature, 2013, v. 493, n. 7430, p. 106, doi. 10.1038/nature11693
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- Publication type:
- Article
Erratum to: Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.
- Published in:
- 2018
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- Publication type:
- journal article
Action and function of Wnt/β-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma.
- Published in:
- 2017
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- Publication type:
- journal article
Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection
- Published in:
- FEBS Letters, 2011, v. 585, n. 7, p. 1025, doi. 10.1016/j.febslet.2011.02.035
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- Publication type:
- Article
A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis.
- Published in:
- PLoS Genetics, 2009, v. 5, n. 7, p. 1, doi. 10.1371/journal.pgen.1000547
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- Publication type:
- Article
The ‘just-right’ signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade.
- Published in:
- Human Molecular Genetics, 2002, v. 11, n. 13, p. 1549, doi. 10.1093/hmg/11.13.1549
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- Publication type:
- Article
Some fine-structural findings on the thyroid gland in Apc mice that express a C-terminus lacking truncated Apc.
- Published in:
- Medical Molecular Morphology, 2012, v. 45, n. 3, p. 161, doi. 10.1007/s00795-011-0553-4
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- Publication type:
- Article
The C-terminal domain of the adenomatous polyposis coli (Apc) protein is involved in thyroid morphogenesis and function.
- Published in:
- Medical Molecular Morphology, 2011, v. 44, n. 4, p. 207, doi. 10.1007/s00795-010-0529-9
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- Publication type:
- Article
APC, SIGNAL TRANSDUCTION AND GENETIC INSTABILITY IN COLORECTAL CANCER.
- Published in:
- Nature Reviews Cancer, 2001, v. 1, n. 1, p. 55, doi. 10.1038/35094067
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- Publication type:
- Article
Differentially Methylated Regions in Desmoid-Type Fibromatosis: A Comparison Between CTNNB1 S45F and T41A Tumors.
- Published in:
- Frontiers in Oncology, 2020, v. 11, p. N.PAG, doi. 10.3389/fonc.2020.565031
- By:
- Publication type:
- Article
LGR5 marks targetable tumor-initiating cells in mouse liver cancer.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-15846-0
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- Publication type:
- Article