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Success in Navigating Hurdles to Oral Delivery of a Bioactive Peptide Complement Antagonist through Use of Nanoparticles to Increase Bioavailability and In Vivo Efficacy.
- Published in:
- Advanced Therapeutics, 2022, v. 5, n. 12, p. 1, doi. 10.1002/adtp.202200109
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- Publication type:
- Article
Success in Navigating Hurdles to Oral Delivery of a Bioactive Peptide Complement Antagonist through Use of Nanoparticles to Increase Bioavailability and In Vivo Efficacy (Adv. Therap. 12/2022).
- Published in:
- Advanced Therapeutics, 2022, v. 5, n. 12, p. 1, doi. 10.1002/adtp.202270030
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- Article
Journey to the Market: The Evolution of Biodegradable Drug Delivery Systems.
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- Applied Sciences (2076-3417), 2022, v. 12, n. 2, p. 935, doi. 10.3390/app12020935
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- Publication type:
- Article
Pharmacological characterization of the chronic phase of the monoiodoacetate‐induced rat model of osteoarthritis pain in the knee joint.
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- Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 11, p. 1515, doi. 10.1111/1440-1681.13551
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- Article
Optimisation of a Microfluidic Method for the Delivery of a Small Peptide.
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- Pharmaceutics, 2021, v. 13, n. 9, p. 1505, doi. 10.3390/pharmaceutics13091505
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- Publication type:
- Article
Assessment of the Anti-Allodynic and Anti-Hyperalgesic Efficacy of a Glycine Transporter 2 Inhibitor Relative to Pregabalin, Duloxetine and Indomethacin in a Rat Model of Cisplatin-Induced Peripheral Neuropathy.
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- Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 940, doi. 10.3390/biom11070940
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- Article
Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods.
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- Clinical & Experimental Pharmacology & Physiology, 2021, v. 48, n. 1, p. 96, doi. 10.1111/1440-1681.13402
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- Article
Assessment of the anti‐hyperalgesic efficacy of J‐2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP).
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- Clinical & Experimental Pharmacology & Physiology, 2020, v. 47, n. 12, p. 1912, doi. 10.1111/1440-1681.13383
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- Article
Comparative studies of glial fibrillary acidic protein and brain‐derived neurotrophic factor expression in two transgenic mouse models of Alzheimer's disease.
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- Clinical & Experimental Pharmacology & Physiology, 2020, v. 47, n. 10, p. 1740, doi. 10.1111/1440-1681.13363
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- Publication type:
- Article
Use of Microfluidics to Fabricate Bioerodable Lipid Hybrid Nanoparticles Containing Hydromorphone or Ketamine for the Relief of Intractable Pain.
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- Pharmaceutical Research, 2020, v. 37, n. 10, p. 1, doi. 10.1007/s11095-020-02939-0
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- Publication type:
- Article
Transcriptomic characterisation of the optimised rat model of Walker 256 breast cancer cell‐induced bone pain.
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- Clinical & Experimental Pharmacology & Physiology, 2019, v. 46, n. 12, p. 1201, doi. 10.1111/1440-1681.13165
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- Publication type:
- Article
Nitric oxide modulates μ‐opioid receptor function in vitro.
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- Clinical & Experimental Pharmacology & Physiology, 2019, v. 46, n. 7, p. 676, doi. 10.1111/1440-1681.13091
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- Publication type:
- Article
In vivo profiling of four centrally administered opioids for antinociception, constipation and respiratory depression: Between‐colony differences in Sprague Dawley rats.
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- Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 10, p. 1056, doi. 10.1111/1440-1681.12972
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- Publication type:
- Article
Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin‐induced peripheral neuropathy.
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- Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 10, p. 1067, doi. 10.1111/1440-1681.12971
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- Publication type:
- Article
Inhibition of acid-sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain.
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- 2018
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- Publication type:
- journal article
The Somatostatin Receptor-4 Agonist J-2156 Alleviates Mechanical Hypersensitivity in a Rat Model of Breast Cancer Induced Bone Pain.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00495
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- Publication type:
- Article
Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment.
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- Clinical & Experimental Pharmacology & Physiology, 2018, v. 45, n. 1, p. 42, doi. 10.1111/1440-1681.12855
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- Publication type:
- Article
Attenuation of the Infiltration of Angiotensin II Expressing CD3<sup>+</sup> T-Cells and the Modulation of Nerve Growth Factor in Lumbar Dorsal Root Ganglia - A Possible Mechanism Underpinning Analgesia Produced by EMA300, An Angiotensin II Type 2 (AT<sub>2</sub>) Receptor Antagonist
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- Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00389
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- Article
Establishment and Characterization of a Novel Rat Model of Mechanical Low Back Pain Using Behavioral, Pharmacologic and Histologic Methods.
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- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00493
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- Publication type:
- Article
Optimization and In Vivo Profiling of a Refined Rat Model of Walker 256 Breast Cancer Cell-Induced Bone Pain Using Behavioral, Radiological, Histological, Immunohistochemical and Pharmacological Methods.
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- Frontiers in Pharmacology, 2017, p. 1, doi. 10.3389/fphar.2017.00442
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- Publication type:
- Article
The Walker 256 Breast Cancer Cell-Induced Bone Pain Model in Rats.
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- Frontiers in Pharmacology, 2016, v. 7, p. 1, doi. 10.3389/fphar.2016.00286
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- Article
Bioerodable PLGA-Based Microparticles for Producing Sustained-Release Drug Formulations and Strategies for Improving Drug Loading.
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- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00185
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- Publication type:
- Article
Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain.
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- Frontiers in Behavioral Neuroscience, 2016, p. 1, doi. 10.3389/fnbeh.2016.00088
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- Publication type:
- Article
Evaluation of a High-Throughput Peptide Reactivity Format Assay for Assessment of the Skin Sensitization Potential of Chemicals.
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- Frontiers in Pharmacology, 2016, p. 1, doi. 10.3389/fphar.2016.00053
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- Publication type:
- Article
Frontispiece: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 11, p. n/a, doi. 10.1002/anie.201681161
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- Publication type:
- Article
Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.
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- Angewandte Chemie International Edition, 2016, v. 55, n. 11, p. 3580, doi. 10.1002/anie.201510675
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- Publication type:
- Article
The furoxan nitric oxide donor, PRG150, evokes dose-dependent analgesia in a rat model of painful diabetic neuropathy.
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- Clinical & Experimental Pharmacology & Physiology, 2015, v. 42, n. 9, p. 921, doi. 10.1111/1440-1681.12442
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- Article
Neurotrophins and Neuropathic Pain: Role in Pathobiology.
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- Molecules, 2015, v. 20, n. 6, p. 10657, doi. 10.3390/molecules200610657
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- Publication type:
- Article
Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signaling in the dorsal horn of the spinal cord.
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- Pharmacology Research & Perspectives, 2015, v. 3, n. 3, p. 1, doi. 10.1002/prp2.137
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- Article
In vivo High Angular Resolution Diffusion-Weighted Imaging of Mouse Brain at 16.4 Tesla.
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- PLoS ONE, 2015, v. 10, n. 6, p. 1, doi. 10.1371/journal.pone.0130133
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- Article
In vitro methods for hazard assessment of industrial chemicals - opportunities and challenges.
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- Frontiers in Pharmacology, 2015, p. 1, doi. 10.3389/fphar.2015.00094
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- Publication type:
- Article
Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease.
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- Clinical & Experimental Pharmacology & Physiology, 2014, v. 41, n. 10, p. 798, doi. 10.1111/1440-1681.12277
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- Publication type:
- Article
Comment on 'protective arms of the renin-angiotensin system in neurological disease'.
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- 2013
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- Publication type:
- Letter
Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?
- Published in:
- Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 3, p. 726, doi. 10.1093/jac/dks435
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- Publication type:
- Article
The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation.
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- BMC Anesthesiology, 2013, v. 13, n. 1, p. 7, doi. 10.1186/1471-2253-13-7
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- Publication type:
- Article
Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation.
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- Critical Care, 2012, v. 16, n. 5, p. 11679, doi. 10.1186/cc11679
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- Publication type:
- Article
Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation.
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- 2012
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- Publication type:
- journal article
Lipo-Endomorphin-1 Derivatives with Systemic Activity against Neuropathic Pain without Producing Constipation.
- Published in:
- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0041909
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- Publication type:
- Article
Development of simulated and ovine models of extracorporeal life support to improve understanding of circuit-host interactions.
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- Critical Care & Resuscitation, 2012, v. 14, n. 2, p. 105, doi. 10.1016/s1441-2772(23)01583-1
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- Publication type:
- Article
ASAP ECMO: Antibiotic, Sedative and Analgesic Pharmacokinetics during Extracorporeal Membrane Oxygenation: a multi-centre study to optimise drug therapy during ECMO.
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- BMC Anesthesiology, 2012, v. 12, n. 1, p. 29, doi. 10.1186/1471-2253-12-29
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- Publication type:
- Article
Pain, analgesia and genetics.
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- Journal of Pharmacy & Pharmacology, 2011, v. 63, n. 11, p. 1387, doi. 10.1111/j.2042-7158.2011.01340.x
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- Publication type:
- Article
ANTINOCICEPTION VERSUS SERUM CONCENTRATION RELATIONSHIPS FOLLOWING ACUTE ADMINISTRATION OF INTRAVENOUS MORPHINE IN MALE AND FEMALE SPRAGUE-DAWLEY RATS: DIFFERENCES BETWEEN THE TAIL FLICK AND HOT PLATE NOCICEPTIVE TESTS.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2009, v. 36, n. 1, p. 20, doi. 10.1111/j.1440-1681.2008.05019.x
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- Publication type:
- Article
SEX DIFFERENCES IN THE PHARMACOKINETICS, OXIDATIVE METABOLISM AND ORAL BIOAVAILABILITY OF OXYCODONE IN THE SPRAGUE-DAWLEY RAT.
- Published in:
- Clinical & Experimental Pharmacology & Physiology, 2008, v. 35, n. 3, p. 295, doi. 10.1111/j.1440-1681.2007.04821.x
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- Publication type:
- Article
An Update on the Pharmacological Management of Post-Herpetic Neuralgia and Painful Diabetic Neuropathy.
- Published in:
- CNS Drugs, 2008, v. 22, n. 5, p. 417, doi. 10.2165/00023210-200822050-00005
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- Publication type:
- Article
STUDIES WITH KETAMINE AND ALFENTANIL FOLLOWING FREUND'S COMPLETE ADJUVANT-INDUCED INFLAMMATION IN RATS.
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- Clinical & Experimental Pharmacology & Physiology, 2007, v. 34, n. 5/6, p. 414, doi. 10.1111/j.1440-1681.2007.04581.x
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- Publication type:
- Article
Co-administration of oxycodone and morphine and analgesic synergy re-examined.
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- 2005
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- Publication type:
- Letter
Single-dose and steady-state pharmacokinetics and pharmacodynamics of oxycodone in patients with cancer.
- Published in:
- Clinical Pharmacology & Therapeutics, 1992, v. 52, n. 5, p. 487, doi. 10.1038/clpt.1992.176
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- Publication type:
- Article
Dose-dependent pharmacokinetics of caffeine in humans: Relevance as a test of quantitative liver function.
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- Clinical Pharmacology & Therapeutics, 1990, v. 47, n. 4, p. 516, doi. 10.1038/clpt.1990.66
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- Publication type:
- Article