Works by Smaldone, Giovanni

Results: 47

Editorial: LncRNA and their role on epigenome in cancer.

Published in:

2024

By:

Su, Qi;
Orlandella, Francesca Maria;
Smaldone, Giovanni;
Qi, Yitao

Publication type:

Editorial

A Comprehensive Analysis of the Expression Profiles of KCTD Proteins in Acute Lymphoblastic Leukemia: Evidence of Selective Expression of KCTD1 in T-ALL.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 11, p. 3669, doi. 10.3390/jcm12113669

By:

Buono, Lorena;
Iside, Concetta;
Pecoraro, Giovanni;
De Matteo, Antonia;
Beneduce, Giuliana;
Penta de Vera d'Aragona, Roberta;
Parasole, Rosanna;
Mirabelli, Peppino;
Vitagliano, Luigi;
Salvatore, Marco;
Smaldone, Giovanni

Publication type:

Article

Self-Supporting Hydrogels Based on Fmoc-Derivatized Cationic Hexapeptides for Potential Biomedical Applications.

Published in:

Biomedicines, 2021, v. 9, n. 6, p. 678, doi. 10.3390/biomedicines9060678

By:

Diaferia, Carlo;
Rosa, Elisabetta;
Gallo, Enrico;
Smaldone, Giovanni;
Stornaiuolo, Mariano;
Morelli, Giancarlo;
Accardo, Antonella

Publication type:

Article

The lncRNA TEX41 is upregulated in pediatric B-Cells Acute Lymphoblastic Leukemia and it is necessary for leukemic cell growth.

Published in:

Biomarker Research, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40364-021-00307-7

By:

Orlandella, Francesca Maria;
Smaldone, Giovanni;
Salvatore, Giuliana;
Vitagliano, Luigi;
Cianflone, Alessandra;
Parasole, Rosanna;
Beneduce, Giuliana;
Menna, Giuseppe;
Salvatore, Marco;
Mirabelli, Peppino

Publication type:

Article

Role of immune-checkpoint LAG3 as a biomarker finding tool in patient-derived organoid cultures of breast cancer.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-83061-8

By:

Carrese, Barbara;
Coppola, Luigi;
Smaldone, Giovanni;
D'Aiuto, Massimiliano;
Mossetti, Gennaro;
Febbraro, Antonio;
Soricelli, Andrea;
Salvatore, Marco;
Ciaramella, Vincenza

Publication type:

Article

Fmoc-FF hydrogels and nanogels for improved and selective delivery of dexamethasone in leukemic cells and diagnostic applications.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-60145-z

By:

Gallo, Enrico;
Diaferia, Carlo;
Smaldone, Giovanni;
Rosa, Elisabetta;
Pecoraro, Giovanni;
Morelli, Giancarlo;
Accardo, Antonella

Publication type:

Article

Fmoc-FF Nanogel-Mediated Delivery of Doxorubicin and Curcumin in Thyroid Cancer Cells.

Published in:

Pharmaceutics, 2025, v. 17, n. 2, p. 263, doi. 10.3390/pharmaceutics17020263

By:

Gallo, Enrico;
Smaldone, Giovanni;
Cimmino, Luca;
Braile, Mariantonia;
Orlandella, Francesca Maria;
Luciano, Neila;
Accardo, Antonella;
Salvatore, Giuliana

Publication type:

Article

Caveolin-Mediated Internalization of Fmoc-FF Nanogels in Breast Cancer Cell Lines.

Published in:

Pharmaceutics, 2023, v. 15, n. 3, p. 1026, doi. 10.3390/pharmaceutics15031026

By:

Smaldone, Giovanni;
Rosa, Elisabetta;
Gallo, Enrico;
Diaferia, Carlo;
Morelli, Giancarlo;
Stornaiuolo, Mariano;
Accardo, Antonella

Publication type:

Article

Impact of a Single Point Mutation on the Antimicrobial and Fibrillogenic Properties of Cryptides from Human Apolipoprotein B.

Published in:

Pharmaceuticals (14248247), 2021, v. 14, n. 7, p. 631, doi. 10.3390/ph14070631

By:

Gaglione, Rosa;
Smaldone, Giovanni;
Cesaro, Angela;
Rumolo, Mariano;
De Luca, Maria;
Di Girolamo, Rocco;
Petraccone, Luigi;
Del Vecchio, Pompea;
Oliva, Rosario;
Notomista, Eugenio;
Pedone, Emilia;
Arciello, Angela

Publication type:

Article

Elucidating the role of the pLG72 R30K substitution in schizophrenia susceptibility.

Published in:

FEBS Letters, 2017, v. 591, n. 4, p. 646, doi. 10.1002/1873-3468.12585

By:

Sacchi, Silvia;
Cappelletti, Pamela;
Pirone, Luciano;
Smaldone, Giovanni;
Pedone, Emilia;
Pollegioni, Loredano

Publication type:

Article

The BTB domains of the potassium channel tetramerization domain proteins prevalently assume pentameric states.

Published in:

FEBS Letters, 2016, v. 590, n. 11, p. 1663, doi. 10.1002/1873-3468.12203

By:

Smaldone, Giovanni;
Pirone, Luciano;
Pedone, Emilia;
Marlovits, Thomas;
Vitagliano, Luigi;
Ciccarelli, Luciano

Publication type:

Article

Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes.

Published in:

FEBS Letters, 2015, v. 589, n. 7, p. 798, doi. 10.1016/j.febslet.2015.02.012

By:

Smaldone, Giovanni;
Diana, Donatella;
Pollegioni, Loredano;
Di Gaetano, Sonia;
Fattorusso, Roberto;
Pedone, Emilia

Publication type:

Article

The non‐swapped monomeric structure of the arginine‐binding protein from Thermotoga maritima.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2019, v. 75, n. 11, p. 707, doi. 10.1107/S2053230X1901464X

By:

Smaldone, Giovanni;
Ruggiero, Alessia;
Balasco, Nicole;
Abuhammad, Areej;
Autiero, Ida;
Caruso, Daniela;
Esposito, Davide;
Ferraro, Giarita;
Gelardi, Edoardo L. M.;
Moreira, Miguel;
Quareshy, Mussa;
Romano, Maria;
Saaret, Annica;
Selvam, Irwin;
Squeglia, Flavia;
Troisi, Romualdo;
Kroon-Batenburg, Loes M. J.;
Esposito, Luciana;
Berisio, Rita;
Vitagliano, Luigi

Publication type:

Article

Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1502405

By:

Pecoraro, Giovanni;
Leone, Ilaria;
Nuzzo, Silvia;
Negueruela, Santiago;
Smaldone, Giovanni;
Buono, Lorena

Publication type:

Article

LINC00958 as new diagnostic and prognostic biomarker of childhood acute lymphoblastic leukaemia of B cells.

Published in:

Frontiers in Oncology, 2024, p. 1, doi. 10.3389/fonc.2024.1388154

By:

Altieri, Filomena;
Buono, Lorena;
Lanzilli, Mariamichela;
Mirabelli, Peppino;
Cianflone, Alessandra;
Beneduce, Giuliana;
De Matteo, Antonia;
Parasole, Rosanna;
Salvatore, M.;
Smaldone, Giovanni

Publication type:

Article

A Comprehensive Analysis of the Structural Recognition between KCTD Proteins and Cullin 3.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1881, doi. 10.3390/ijms25031881

By:

Balasco, Nicole;
Esposito, Luciana;
Smaldone, Giovanni;
Salvatore, Marco;
Vitagliano, Luigi

Publication type:

Article

Members of the GADD45 Protein Family Show Distinct Propensities to form Toxic Amyloid-Like Aggregates in Physiological Conditions.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 19, p. 10700, doi. 10.3390/ijms221910700

By:

Smaldone, Giovanni;
Caruso, Daniela;
Sandomenico, Annamaria;
Iaccarino, Emanuela;
Focà, Annalia;
Ruggiero, Alessia;
Ruvo, Menotti;
Vitagliano, Luigi

Publication type:

Article

Development of a Protein Scaffold for Arginine Sensing Generated through the Dissection of the Arginine-Binding Protein from Thermotoga maritima.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 20, p. 7503, doi. 10.3390/ijms21207503

By:

Smaldone, Giovanni;
Ruggiero, Alessia;
Balasco, Nicole;
Vitagliano, Luigi

Publication type:

Article

The TUSC2 Tumour Suppressor Inhibits the Malignant Phenotype of Human Thyroid Cancer Cells via SMAC/DIABLO Protein.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 3, p. 702, doi. 10.3390/ijms21030702

By:

Mariniello, Raffaela Mariarosaria;
Maria Orlandella, Francesca;
De Stefano, Anna Elisa;
Iervolino, Paola Lucia Chiara;
Smaldone, Giovanni;
Luciano, Neila;
Cervone, Nara;
Munciguerra, Francesco;
Esposito, Silvia;
Mirabelli, Peppino;
Salvatore, Giuliana

Publication type:

Article

KCTD15 is overexpressed in human childhood B-cell acute lymphoid leukemia.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-56701-7

By:

Smaldone, Giovanni;
Beneduce, Giuliana;
Incoronato, Mariarosaria;
Pane, Katia;
Franzese, Monica;
Coppola, Luigi;
Cordella, Angela;
Parasole, Rosanna;
Ripaldi, Mimmo;
Nassa, Giovanni;
Soricelli, Andrea;
Vitagliano, Luigi;
Mirabelli, Peppino;
Salvatore, Marco

Publication type:

Article

Molecular basis of the scalp-ear-nipple syndrome unraveled by the characterization of disease-causing KCTD1 mutants.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-46911-4

By:

Smaldone, Giovanni;
Balasco, Nicole;
Pirone, Luciano;
Caruso, Daniela;
Di Gaetano, Sonia;
Pedone, Emilia Maria;
Vitagliano, Luigi

Publication type:

Article

The characterization of Thermotoga maritima Arginine Binding Protein variants demonstrates that minimal local strains have an important impact on protein stability.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-43157-y

By:

Balasco, Nicole;
Smaldone, Giovanni;
Vigorita, Marilisa;
Del Vecchio, Pompea;
Graziano, Giuseppe;
Ruggiero, Alessia;
Vitagliano, Luigi

Publication type:

Article

lncRNAs–mRNAs Co–Expression Network Underlying Childhood B–Cell Acute Lymphoblastic Leukaemia: A Pilot Study.

Published in:

Cancers, 2020, v. 12, n. 9, p. 2489, doi. 10.3390/cancers12092489

By:

Affinito, Ornella;
Pane, Katia;
Smaldone, Giovanni;
Orlandella, Francesca Maria;
Mirabelli, Peppino;
Beneduce, Giuliana;
Parasole, Rosanna;
Ripaldi, Mimmo;
Salvatore, Marco;
Franzese, Monica

Publication type:

Article

AlphaFold-Predicted Structures of KCTD Proteins Unravel Previously Undetected Relationships among the Members of the Family.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 12, p. 1862, doi. 10.3390/biom11121862

By:

Esposito, Luciana;
Balasco, Nicole;
Smaldone, Giovanni;
Berisio, Rita;
Ruggiero, Alessia;
Vitagliano, Luigi

Publication type:

Article

The Structural Versatility of the BTB Domains of KCTD Proteins and Their Recognition of the GABAB Receptor.

Published in:

Biomolecules (2218-273X), 2019, v. 9, n. 8, p. 323, doi. 10.3390/biom9080323

By:

Balasco, Nicole;
Smaldone, Giovanni;
Vitagliano, Luigi;
Calderone, Vito

Publication type:

Article

Influence of Breast Cancer Extracellular Vesicles on Immune Cell Activation: A Pilot Study.

Published in:

Biology (2079-7737), 2023, v. 12, n. 12, p. 1531, doi. 10.3390/biology12121531

By:

Santoro, Jessie;
Carrese, Barbara;
Peluso, Maria Sara;
Coppola, Luigi;
D'Aiuto, Massimiliano;
Mossetti, Gennaro;
Salvatore, Marco;
Smaldone, Giovanni

Publication type:

Article

The Oncosuppressive Properties of KCTD1: Its Role in Cell Growth and Mobility.

Published in:

Biology (2079-7737), 2023, v. 12, n. 3, p. 481, doi. 10.3390/biology12030481

By:

Smaldone, Giovanni;
Pecoraro, Giovanni;
Pane, Katia;
Franzese, Monica;
Ruggiero, Alessia;
Vitagliano, Luigi;
Salvatore, Marco

Publication type:

Article

Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 37, p. 12217, doi. 10.1002/chem.201302168

By:

Diana, Donatella;
Smaldone, Giovanni;
De Antonellis, Pasquale;
Pirone, Luciano;
Carotenuto, MariaNeve;
Alonzi, Alessandro;
Di Gaetano, Sonia;
Zollo, Massimo;
Pedone, Emilia M.;
Fattorusso, Roberto

Publication type:

Article

The Marine Isolate Novosphingobium sp. PP1Y Shows Specific Adaptation to Use the Aromatic Fraction of Fuels as the Sole Carbon and Energy Source.

Published in:

Microbial Ecology, 2011, v. 61, n. 3, p. 582, doi. 10.1007/s00248-010-9786-3

By:

Notomista, Eugenio;
Pennacchio, Francesca;
Cafaro, Valeria;
Smaldone, Giovanni;
Izzo, Viviana;
Troncone, Luca;
Varcamonti, Mario;
Donato, Alberto

Publication type:

Article

Identification of Immune Cell Components in Breast Tissues by a Multiparametric Flow Cytometry Approach.

Published in:

Cancers, 2022, v. 14, n. 16, p. 3869, doi. 10.3390/cancers14163869

By:

Coppola, Luigi;
Smaldone, Giovanni;
D'aiuto, Massimiliano;
D'aiuto, Giuseppe;
Mossetti, Gennaro;
Rinaldo, Massimo;
Verticilo, Simona;
Nicolai, Emanuele;
Salvatore, Marco;
Mirabelli, Peppino

Publication type:

Article

Neuroimaging in Nonsyndromic Craniosynostosis: Key Concepts to Unlock Innovation.

Published in:

Diagnostics (2075-4418), 2024, v. 14, n. 17, p. 1842, doi. 10.3390/diagnostics14171842

By:

Russo, Camilla;
Aliberti, Ferdinando;
Ferrara, Ursula Pia;
Russo, Carmela;
De Gennaro, Domenico Vincenzo;
Cristofano, Adriana;
Nastro, Anna;
Cicala, Domenico;
Spennato, Pietro;
Quarantelli, Mario;
Aiello, Marco;
Soricelli, Andrea;
Smaldone, Giovanni;
Onorini, Nicola;
De Martino, Lucia;
Picariello, Stefania;
Parlato, Stefano;
Mirabelli, Peppino;
Quaglietta, Lucia;
Covelli, Eugenio Maria

Publication type:

Article

KCTD15 Is Overexpressed in her2+ Positive Breast Cancer Patients and Its Silencing Attenuates Proliferation in SKBR3 CELL LINE.

Published in:

Diagnostics (2075-4418), 2022, v. 12, n. 3, p. 591, doi. 10.3390/diagnostics12030591

By:

Coppola, Luigi;
Baselice, Simona;
Messina, Francesco;
Giannatiempo, Rosa;
Farina, Amalia;
Vitagliano, Luigi;
Smaldone, Giovanni;
Salvatore, Marco

Publication type:

Article

KCTD15 Protein Expression in Peripheral Blood and Acute Myeloid Leukemia.

Published in:

Diagnostics (2075-4418), 2020, v. 10, n. 6, p. 371, doi. 10.3390/diagnostics10060371

By:

Smaldone, Giovanni;
Coppola, Luigi;
Incoronato, Mariarosaria;
Parasole, Rosanna;
Ripaldi, Mimmo;
Vitagliano, Luigi;
Mirabelli, Peppino;
Salvatore, Marco

Publication type:

Article

Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142711

By:

Karlsson, Jessica;
Morgillo, Carmine M.;
Deplano, Alessandro;
Smaldone, Giovanni;
Pedone, Emilia;
Luque, F. Javier;
Svensson, Mona;
Novellino, Ettore;
Congiu, Cenzo;
Onnis, Valentina;
Catalanotti, Bruno;
Fowler, Christopher J.

Publication type:

Article

Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0126808

By:

Smaldone, Giovanni;
Pirone, Luciano;
Balasco, Nicole;
Di Gaetano, Sonia;
Pedone, Emilia Maria;
Vitagliano, Luigi

Publication type:

Article

Specific lncRNA signatures discriminate childhood acute leukaemias: a pilot study.

Published in:

Cancer Cell International, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12935-022-02789-3

By:

Buono, Lorena;
Iside, Concetta;
De Matteo, Antonia;
Stellato, Pio;
Beneduce, Giuliana;
de Vera d'Aragona, Roberta Penta;
Parasole, Rosanna;
Salvatore, Marco;
Smaldone, Giovanni;
Mirabelli, Peppino

Publication type:

Article

Correction: Biobank for craniosynostosis and faciocraniosynostosis, rare pediatric congenital craniofacial disorders: a study protocol.

Published in:

2024

By:

De Martino, Lucia;
Mirabelli, Peppino;
Quaglietta, Lucia;
Ferrara, Ursula Pia;
Picariello, Stefania;
De Gennaro, Domenico Vincenzo;
Aiello, Marco;
Smaldone, Giovanni;
Aliberti, Ferdinando;
Spennato, Pietro;
De Brasi, Daniele;
Covelli, Eugenio;
Cinalli, Giuseppe

Publication type:

Correction Notice

Biobank for craniosynostosis and faciocraniosynostosis, rare pediatric congenital craniofacial disorders: a study protocol.

Published in:

Child's Nervous System, 2024, v. 40, n. 11, p. 3693, doi. 10.1007/s00381-024-06555-w

By:

De Martino, Lucia;
Mirabelli, Peppino;
Quaglietta, Lucia;
Ferrara, Ursula Pia;
Picariello, Stefania;
De Gennaro, Domenico Vincenzo;
Aiello, Marco;
Smaldone, Giovanni;
Aliberti, Ferdinando;
Spennato, Pietro;
De Brasi, Daniele;
Covelli, Eugenio;
Cinalli, Giuseppe

Publication type:

Article

Exploring thymic stromal lymphopoietin in the breast cancer microenvironment: A preliminary study.

Published in:

Oncology Letters, 2025, v. 29, n. 4, p. N.PAG, doi. 10.3892/ol.2025.14928

By:

Marcella, Simone;
Braile, Mariantonia;
Grimaldi, Anna Maria;
Soricelli, Andrea;
Smaldone, Giovanni

Publication type:

Article

KCTD15 deregulation is associated with alterations of the NF-κB signaling in both pathological and physiological model systems.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-97775-6

By:

Smaldone, Giovanni;
Coppola, Luigi;
Pane, Katia;
Franzese, Monica;
Beneduce, Giuliana;
Parasole, Rosanna;
Menna, Giuseppe;
Vitagliano, Luigi;
Salvatore, Marco;
Mirabelli, Peppino

Publication type:

Article

Purification of viable peripheral blood mononuclear cells for biobanking using a robotized liquid handling workstation.

Published in:

2019

By:

Coppola, Luigi;
Smaldone, Giovanni;
Cianflone, Alessandra;
Baselice, Simona;
Mirabelli, Peppino;
Salvatore, Marco

Publication type:

journal article

Multicomponent Hydrogel Matrices of Fmoc‐FF and Cationic Peptides for Application in Tissue Engineering.

Published in:

Macromolecular Bioscience, 2022, v. 22, n. 7, p. 1, doi. 10.1002/mabi.202200128

By:

Rosa, Elisabetta;
Diaferia, Carlo;
Gianolio, Eliana;
Sibillano, Teresa;
Gallo, Enrico;
Smaldone, Giovanni;
Stornaiuolo, Mariano;
Giannini, Cinzia;
Morelli, Giancarlo;
Accardo, Antonella

Publication type:

Article

Peptide-Based Hydrogels and Nanogels for Delivery of Doxorubicin.

Published in:

International Journal of Nanomedicine, 2021, v. 16, p. 1617, doi. 10.2147/IJN.S296272

By:

Gallo, Enrico;
Diaferia, Carlo;
Rosa, Elisabetta;
Smaldone, Giovanni;
Morelli, Giancarlo;
Accardo, Antonella

Publication type:

Article

gH625 is a viral derived peptide for effective delivery of intrinsically disordered proteins.

Published in:

International Journal of Nanomedicine, 2013, v. 8, p. 2555, doi. 10.2147/IJN.S44186

By:

Smaldone, Giovanni;
Falanga, Annarita;
Capasso, Domenica;
Guarnieri, Daniela;
Correale, Stefania;
Galdiero, Massimiliano;
Netti, Paolo A.;
Zollo, Massimo;
Galdiero, Stefania;
Di Gaetano, Sonia;
Pedone, Emilia

Publication type:

Article

Loop size optimization induces a strong thermal stabilization of the thioredoxin fold.

Published in:

FEBS Journal, 2019, v. 286, n. 9, p. 1752, doi. 10.1111/febs.14767

By:

Ruggiero, Alessia;
Smaldone, Giovanni;
Esposito, Luciana;
Balasco, Nicole;
Vitagliano, Luigi

Publication type:

Article

Regulating levels of the neuromodulator d-serine in human brain: structural insight into pLG72 and d-amino acid oxidase interaction.

Published in:

FEBS Journal, 2016, v. 283, n. 18, p. 3353, doi. 10.1111/febs.13809

By:

Birolo, Leila;
Sacchi, Silvia;
Smaldone, Giovanni;
Molla, Gianluca;
Leo, Gabriella;
Caldinelli, Laura;
Pirone, Luciano;
Eliometri, Patrick;
Di Gaetano, Sonia;
Orefice, Ida;
Pedone, Emilia;
Pucci, Piero;
Pollegioni, Loredano

Publication type:

Article

A new cryptic cationic antimicrobial peptide from human apolipoprotein E with antibacterial activity and immunomodulatory effects on human cells.

Published in:

FEBS Journal, 2016, v. 283, n. 11, p. 2115, doi. 10.1111/febs.13725

By:

Pane, Katia;
Sgambati, Valeria;
Zanfardino, Anna;
Smaldone, Giovanni;
Cafaro, Valeria;
Angrisano, Tiziana;
Pedone, Emilia;
Di Gaetano, Sonia;
Capasso, Domenica;
Haney, Evan F.;
Izzo, Viviana;
Varcamonti, Mario;
Notomista, Eugenio;
Hancock, Robert E.W.;
Di Donato, Alberto;
Pizzo, Elio

Publication type:

Article