Works by Sleno, Lekha

Results: 44

Synergistic properties of bioavailable phenolic compounds from olive oil: electron transfer and neuroprotective properties.

Published in:

Nutritional Neuroscience, 2021, v. 24, n. 9, p. 660, doi. 10.1080/1028415X.2019.1666480

By:

Lambert de Malezieu, Morgane;
Courtel, Patricia;
Sleno, Lekha;
Abasq, Marie-Laurence;
Ramassamy, Charles

Publication type:

Article

Sensitivity of Scenedesmus obliquus and Microcystis aeruginosa to atrazine: effects of acclimation and mixed cultures, and their removal ability.

Published in:

Ecotoxicology, 2016, v. 25, n. 10, p. 1822, doi. 10.1007/s10646-016-1728-5

By:

Chalifour, Annie;
LeBlanc, André;
Sleno, Lekha;
Juneau, Philippe

Publication type:

Article

Investigating Byssogenesis with Proteomic Analysis of Byssus, Foot, and Mantle in Mytilus Mussels by LC‐MS/MS.

Published in:

Proteomics, 2021, v. 21, n. 2, p. 1, doi. 10.1002/pmic.202000014

By:

Sansoucy, Maxime;
Tremblay, Réjean;
Carrington, Emily;
Marcotte, Isabelle;
Sleno, Lekha

Publication type:

Article

A Covalent Cysteine-Targeting Kinase Inhibitor of Ire1 Permits Allosteric Control of Endoribonuclease Activity.

Published in:

ChemBioChem, 2016, v. 17, n. 9, p. 843, doi. 10.1002/cbic.201500485

By:

Waller, Daniel D.;
Jansen, Gregor;
Golizeh, Makan;
Martel‐Lorion, Chloe;
Dejgaard, Kurt;
Shiao, Tze Chieh;
Mancuso, John;
Tsantrizos, Youla S.;
Roy, René;
Sebag, Michael;
Sleno, Lekha;
Thomas, David Y.

Publication type:

Article

Absorption and Metabolism of Phenolics from Digests of Polyphenol-Rich Potato Extracts Using the Caco-2/HepG2 Co-Culture System.

Published in:

Foods, 2018, v. 7, n. 1, p. 8, doi. 10.3390/foods7010008

By:

Sadeghi Ekbatan, Shima;
Iskandar, Michele M.;
Sleno, Lekha;
Sabally, Kebba;
Khairallah, Joelle;
Prakash, Satya;
Kubow, Stan

Publication type:

Article

An evaluation of oral dabigatran etexilate pharmacokinetics and pharmacodynamics in hemodialysis.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 8, p. 901, doi. 10.1002/jcph.335

By:

Wilson, Jo‐Anne S.;
Goralski, Kerry B.;
Soroka, Steven D.;
Morrison, Matthew;
Mossop, Paula;
Sleno, Lekha;
Wang, Yan;
Anderson, David R.

Publication type:

Article

Correction: Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models.

Published in:

2023

By:

McKeown, Brendan T.;
Relja, Nicholas J.;
Hall, Steven R.;
Gebremeskel, Simon;
MacLeod, Jeanna M.;
Veinotte, Chansey J.;
Bennett, Leah G.;
Ohlund, Leanne B.;
Sleno, Lekha;
Jakeman, David L.;
Berman, Jason N.;
Johnston, Brent;
Goralski, Kerry B.

Publication type:

Correction Notice

Pilot study of jadomycin B pharmacokinetics and anti-tumoral effects in zebrafish larvae and mouse breast cancer xenograft models.

Published in:

Canadian Journal of Physiology & Pharmacology, 2022, v. 100, n. 11, p. 1065, doi. 10.1139/cjpp-2022-0152

By:

McKeown, Brendan T.;
Relja, Nicholas J.;
Hall, Steven R.;
Gebremeskel, Simon;
MacLeod, Jeanna M.;
Veinotte, Chansey J.;
Bennett, Leah G.;
Ohlund, Leanne B.;
Sleno, Lekha;
Jakeman, David L.;
Berman, Jason N.;
Johnston, Brent;
Goralski, Kerry B.

Publication type:

Article

Perturbations in human bile acid profiles following drug‐induced liver injury investigated using semitargeted high‐resolution mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2024, v. 38, n. 9, p. 1, doi. 10.1002/rcm.9731

By:

Mireault, Myriam;
Rose, Christopher F.;
Karvellas, Constantine J.;
Sleno, Lekha

Publication type:

Article

In vitro metabolism of sunscreen compounds by liquid chromatography/high‐resolution tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2020, v. 34, n. 8, p. 1, doi. 10.1002/rcm.8679

By:

Guesmi, Amal;
Ohlund, Leanne;
Sleno, Lekha

Publication type:

Article

A validated liquid chromatography/tandem mass spectrometry method for 4,4′‐methylenedianiline quantitation in human urine as a measure of 4,4′‐methylene diphenyl diisocyanate exposure.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2019, v. 33, n. 6, p. 600, doi. 10.1002/rcm.8380

By:

Lépine, Maggy;
Sleno, Lekha;
Lesage, Jacques;
Gagné, Sébastien

Publication type:

Article

Absolute quantitation of acetaminophen‐modified human serum albumin in acute liver failure patients by liquid chromatography/tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2018, v. 32, n. 17, p. 1573, doi. 10.1002/rcm.8206

By:

Geib, Timon;
LeBlanc, André;
Shiao, Tze Chieh;
Roy, René;
Leslie, Elaine M.;
Karvellas, Constantine J.;
Sleno, Lekha

Publication type:

Article

Identification of 4-hydroxynonenal protein targets in rat, mouse and human liver microsomes by two-dimensional liquid chromatography/tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2016, v. 30, n. 13, p. 1488, doi. 10.1002/rcm.7577

By:

Golizeh, Makan;
Geib, Timon;
Sleno, Lekha

Publication type:

Article

A validated UPLC-MS/MS method for the determination of aliphatic and aromatic isocyanate exposure in human urine.

Published in:

Analytical & Bioanalytical Chemistry, 2020, v. 412, n. 3, p. 753, doi. 10.1007/s00216-019-02295-y

By:

Lépine, Maggy;
Sleno, Lekha;
Lesage, Jacques;
Gagné, Sébastien

Publication type:

Article

In vitro metabolism of triclosan studied by liquid chromatography–high-resolution tandem mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2020, v. 412, n. 2, p. 335, doi. 10.1007/s00216-019-02239-6

By:

Guesmi, Amal;
Sleno, Lekha

Publication type:

Article

Challenges and recent advances in quantitative mass spectrometry‐based metabolomics.

Published in:

Analytical Science Advances, 2024, v. 5, n. 5/6, p. 1, doi. 10.1002/ansa.202400007

By:

Ghafari, Nathan;
Sleno, Lekha

Publication type:

Article

Determining site occupancy of acetaminophen covalent binding to target proteins in vitro.

Published in:

Analytical Science Advances, 2021, v. 2, n. 5/6, p. 263, doi. 10.1002/ansa.202000182

By:

Geib, Timon;
Lento, Cristina;
Marensi, Vanessa;
Thulasingam, Madhuranayaki;
Haeggström, Jesper Z.;
Olsson, Magnus;
Wilson, Derek J.;
Leslie, Elaine M.;
Sleno, Lekha

Publication type:

Article

Structural Elucidation of Novel Stable and Reactive Metabolites of Green Tea Catechins and Alkyl Gallates by LC-MS/MS.

Published in:

Antioxidants, 2022, v. 11, n. 9, p. 1635, doi. 10.3390/antiox11091635

By:

Ousji, Ons;
Sleno, Lekha

Publication type:

Article

Effects of Simulated Human Gastrointestinal Digestion of Two Purple-Fleshed Potato Cultivars on Anthocyanin Composition and Cytotoxicity in Colonic Cancer and Non-Tumorigenic Cells.

Published in:

Nutrients, 2017, v. 9, n. 9, p. 953, doi. 10.3390/nu9090953

By:

Kubow, Stan;
Iskandar, Michèle M.;
Melgar-Bermudez, Emiliano;
Sleno, Lekha;
Sabally, Kebba;
Azadi, Behnam;
How, Emily;
Prakash, Satya;
Burgos, Gabriela;
Felde, Thomas zum

Publication type:

Article

Carotenoid production and change of photosynthetic functions in Scenedesmus sp. exposed to nitrogen limitation and acetate treatment.

Published in:

Journal of Applied Phycology, 2012, v. 24, n. 1, p. 117, doi. 10.1007/s10811-011-9657-4

By:

Pirastru, Laura;
Darwish, Mohamed;
Chu, Fong;
Perreault, François;
Sirois, Louka;
Sleno, Lekha;
Popovic, Radovan

Publication type:

Article

Diamine Oxidase as a Therapeutic Enzyme: Study of Germination from Vegetal Sources and Investigation of the Presence of β-N-Oxalyl-L-α,β-diaminopropionic Acid (β-ODAP) Using LC-MS/MS.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 5, p. 4625, doi. 10.3390/ijms24054625

By:

Boulfekhar, Rym;
Ohlund, Leanne;
Kumaresan, Kathrina Mae;
Megoura, Meriem;
Warkentin, Thomas D.;
Ispas-Szabo, Pompilia;
Sleno, Lekha;
Mateescu, Mircea Alexandru

Publication type:

Article

Semi-Targeted Profiling of Bile Acids by High-Resolution Mass Spectrometry in a Rat Model of Drug-Induced Liver Injury.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2489, doi. 10.3390/ijms24032489

By:

Mireault, Myriam;
Prinville, Vivaldy;
Ohlund, Leanne;
Sleno, Lekha

Publication type:

Article

Identification of In Vitro Metabolites of Synthetic Phenolic Antioxidants BHT, BHA, and TBHQ by LC-HRMS/MS.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 24, p. 9525, doi. 10.3390/ijms21249525

By:

Ousji, Ons;
Sleno, Lekha

Publication type:

Article

Microbial Biotransformation of a Polyphenol-Rich Potato Extract Affects Antioxidant Capacity in a Simulated Gastrointestinal Model.

Published in:

Antioxidants, 2018, v. 7, n. 3, p. 43, doi. 10.3390/antiox7030043

By:

Khairallah, Joelle;
Sadeghi Ekbatan, Shima;
Sabally, Kebba;
Iskandar, Michèle M.;
Hussain, Raza;
Nassar, Atef;
Sleno, Lekha;
Rodes, Laetitia;
Prakash, Satya;
Donnelly, Danielle J.;
Kubow, Stan

Publication type:

Article

Estradiol, Estrone and Ethinyl Estradiol Metabolism Studied by High Resolution LC-MS/MS Using Stable Isotope Labeling and Trapping of Reactive Metabolites.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 10, p. 931, doi. 10.3390/metabo12100931

By:

Chabi, Kahina;
Sleno, Lekha

Publication type:

Article

Targeted Analysis of 46 Bile Acids to Study the Effect of Acetaminophen in Rat by LC-MS/MS.

Published in:

Metabolites (2218-1989), 2020, v. 10, n. 1, p. 26, doi. 10.3390/metabo10010026

By:

Prinville, Vivaldy;
Ohlund, Leanne;
Sleno, Lekha

Publication type:

Article

Modern drug discovery and the progression toward a universal mass spectrometer.

Published in:

Analytical & Bioanalytical Chemistry, 2005, v. 381, n. 1, p. 90, doi. 10.1007/s00216-004-2826-4

By:

Volmer, Dietrich A.;
Sleno, Lekha

Publication type:

Article

Structural study of spirolide marine toxins by mass spectrometry: Part I. Fragmentation pathways of 13-desmethyl spirolide C by collision-induced dissociation and infrared multiphoton dissociation mass spectrometry.

Published in:

Analytical & Bioanalytical Chemistry, 2004, v. 378, n. 4, p. 969, doi. 10.1007/s00216-003-2297-z

By:

Sleno, Lekha;
Windust, Anthony J;
Volmer, Dietrich A

Publication type:

Article

Structural study of spirolide marine toxins by mass spectrometry: Part II. Mass spectrometric characterization of unknown spirolides and related compounds in a cultured phytoplankton extract.

Published in:

Analytical & Bioanalytical Chemistry, 2004, v. 378, n. 4, p. 977, doi. 10.1007/s00216-003-2296-0

By:

Sleno, Lekha;
Chalmers, Michael J.;
Volmer, Dietrich A.

Publication type:

Article

Les effets d’une réaction inflammatoire induite par chirurgie sur la distribution de morphine et de ses métabolites dans le liquide céphalorachidien : une étude observationnelle.

Published in:

2017

By:

Wang, Yan;
Goralski, Kerry;
Roberts, Derek;
Landry, Kathryn;
Issa, Mark;
Sleno, Lekha;
Julien, Lisa;
Wood, Jeremy;
Hall, Richard;
Goralski, Kerry B;
Roberts, Derek J;
Issa, Mark E;
Julien, Lisa C;
Hall, Richard I

Publication type:

journal article

New insights in copper handling strategies in the green alga Chlamydomonas reinhardtii under low-iron condition.

Published in:

Metallomics, 2022, v. 14, n. 6, p. 1, doi. 10.1093/mtomcs/mfac033

By:

Kochoni, Emeric;
Aharchaou, Imad;
Ohlund, Leanne;
Rosabal, Maikel;
Sleno, Lekha;
Fortin, Claude

Publication type:

Article

The use of mass defect in modern mass spectrometry.

Published in:

Journal of Mass Spectrometry, 2012, v. 47, n. 2, p. 226, doi. 10.1002/jms.2953

By:

Sleno, Lekha

Publication type:

Article

Ion activation methods for tandem mass spectrometry.

Published in:

Journal of Mass Spectrometry, 2004, v. 39, n. 10, p. 1091, doi. 10.1002/jms.703

By:

Sleno, Lekha;
Volmer, Dietrich A.

Publication type:

Article

Isotope-labeled differential profiling of metabolites using N-benzoyloxysuccinimide derivatization coupled to liquid chromatography/high-resolution tandem mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2015, v. 29, n. 18, p. 1632, doi. 10.1002/rcm.7264

By:

Wagner, Michel;
Ohlund, Leanne B.;
Shiao, Tze Chieh;
Vézina, Amélie;
Annabi, Borhane;
Roy, René;
Sleno, Lekha

Publication type:

Article

Comparison of peak-picking workflows for untargeted liquid chromatography/high-resolution mass spectrometry metabolomics data analysis.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2015, v. 29, n. 1, p. 119, doi. 10.1002/rcm.7094

By:

Rafiei, Atefeh;
Sleno, Lekha

Publication type:

Article

Determination of isotopic labeling of proteins by precursor ion scanning liquid chromatography/tandem mass spectrometry of derivatized amino acids applied to nuclear magnetic resonance studies.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2012, v. 26, n. 10, p. 1165, doi. 10.1002/rcm.6204

By:

LeBlanc, André;
Arnold, Alexandre A.;
Genard, Bertrand;
Nadalini, Jean-Bruno;
Heine, Marc-Olivier Séguin;
Marcotte, Isabelle;
Tremblay, Réjean;
Sleno, Lekha

Publication type:

Article

Improved detection of reactive metabolites with a bromine-containing glutathione analog using mass defect and isotope pattern matching.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2010, v. 24, n. 9, p. 1241, doi. 10.1002/rcm.4507

By:

LeBlanc, André;
Shiao, Tze Chieh;
Roy, René;
Sleno, Lekha

Publication type:

Article

Determining protein adducts of fipexide: mass spectrometry based assay for confirming the involvement of its reactive metabolite in covalent binding.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 24, p. 4149, doi. 10.1002/rcm.3329

By:

Sleno, Lekha;
Varesio, Emmanuel;
Hopfgartner, Gérard

Publication type:

Article

Investigating the in vitro metabolism of fipexide: characterization of reactive metabolites using liquid chromatography/mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2007, v. 21, n. 14, p. 2301, doi. 10.1002/rcm.3092

By:

Sleno, Lekha;
Staack, Roland F.;
Varesio, Emmanuel;
Hopfgartner, Gérard

Publication type:

Article

Mass spectral characterization of phloroglucinol derivatives hyperforin and adhyperforin.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2006, v. 20, n. 18, p. 2641, doi. 10.1002/rcm.2650

By:

Sleno, Lekha;
Daneshfar, Rambod;
Eckert, Gunter P.;
Müller, Walter E.;
Volmer, Dietrich A.

Publication type:

Article

Assessing the properties of internal standards for quantitative matrix-assisted laser desorption/ionization mass spectrometry of small molecules.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2006, v. 20, n. 10, p. 1517, doi. 10.1002/rcm.2498

By:

Sleno, Lekha;
Volmer, Dietrich A.

Publication type:

Article

Some fundamental and technical aspects of the quantitative analysis of pharmaceutical drugs by matrix-assisted laser desorption/ionization mass spectrometry.

Published in:

Rapid Communications in Mass Spectrometry: RCM, 2005, v. 19, n. 14, p. 1928, doi. 10.1002/rcm.2006

By:

Sleno, Lekha;
Volmer, Dietrich A.

Publication type:

Article

Surgery‐induced inflammation reduces morphine distribution into cerebrospinal fluid.

Published in:

FASEB Journal, 2013, v. 27, p. 668.2, doi. 10.1096/fasebj.27.1_supplement.668.2

By:

Wang, Yan;
Landry, Kathryn;
Issa, Mark;
Sleno, Lekha;
Julian, Lisa;
Hall, Richard;
Goralski, Kerry

Publication type:

Article

Tolerance and phytoremediation capacity of atrazine and S-metolachlor by two duckweeds.

Published in:

Environmental Science & Pollution Research, 2024, v. 31, n. 49, p. 59382, doi. 10.1007/s11356-024-35122-8

By:

Cruz, Fernanda Vieira da Silva;
Brant, Humberto Soares Caldeira;
Ohlund, Leanne;
Sleno, Lekha;
Juneau, Philippe

Publication type:

Article