Works matching AU Sleiman, Patrick M. A.

Results: 63
    1

    Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.

    Published in:
    JAMA Neurology, 2018, v. 75, n. 7, p. 860, doi. 10.1001/jamaneurol.2018.0372
    By:
    • Karch, Celeste M.;
    • Wen, Natalie;
    • Fan, Chun C.;
    • Yokoyama, Jennifer S.;
    • Kouri, Naomi;
    • Ross, Owen A.;
    • Höglinger, Gunter;
    • Müller, Ulrich;
    • Ferrari, Raffaele;
    • Hardy, John;
    • Schellenberg, Gerard D.;
    • Sleiman, Patrick M.;
    • Momeni, Parastoo;
    • Hess, Christopher P.;
    • Miller, Bruce L.;
    • Sharma, Manu;
    • Van Deerlin, Vivianna;
    • Smeland, Olav B.;
    • Andreassen, Ole A.;
    • Dale, Anders M.
    Publication type:
    Article
    2

    A genome-wide association meta-analysis identifies new childhood obesity loci.

    Published in:
    Nature Genetics, 2012, v. 44, n. 5, p. 526, doi. 10.1038/ng.2247
    By:
    • Bradfield, Jonathan P;
    • Taal, H Rob;
    • Timpson, Nicholas J;
    • Scherag, André;
    • Lecoeur, Cecile;
    • Warrington, Nicole M;
    • Hypponen, Elina;
    • Holst, Claus;
    • Valcarcel, Beatriz;
    • Thiering, Elisabeth;
    • Salem, Rany M;
    • Schumacher, Fredrick R;
    • Cousminer, Diana L;
    • Sleiman, Patrick M A;
    • Zhao, Jianhua;
    • Berkowitz, Robert I;
    • Vimaleswaran, Karani S;
    • Jarick, Ivonne;
    • Pennell, Craig E;
    • Evans, David M
    Publication type:
    Article
    3

    Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

    Published in:
    Nature Genetics, 2012, v. 44, n. 2, p. 187, doi. 10.1038/ng.1017
    By:
    • Paternoster, Lavinia;
    • Standl, Marie;
    • Chen, Chih-Mei;
    • Ramasamy, Adaikalavan;
    • Bønnelykke, Klaus;
    • Duijts, Liesbeth;
    • Ferreira, Manuel A;
    • Alves, Alexessander Couto;
    • Thyssen, Jacob P;
    • Albrecht, Eva;
    • Baurecht, Hansjörg;
    • Feenstra, Bjarke;
    • Sleiman, Patrick M A;
    • Hysi, Pirro;
    • Warrington, Nicole M;
    • Curjuric, Ivan;
    • Myhre, Ronny;
    • Curtin, John A;
    • Groen-Blokhuis, Maria M;
    • Kerkhof, Marjan
    Publication type:
    Article
    4

    Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder.

    Published in:
    Nature Genetics, 2012, v. 44, n. 1, p. 78, doi. 10.1038/ng.1013
    By:
    • Elia, Josephine;
    • Glessner, Joseph T;
    • Wang, Kai;
    • Takahashi, Nagahide;
    • Shtir, Corina J;
    • Hadley, Dexter;
    • Sleiman, Patrick M A;
    • Zhang, Haitao;
    • Kim, Cecilia E;
    • Robison, Reid;
    • Lyon, Gholson J;
    • Flory, James H;
    • Bradfield, Jonathan P;
    • Imielinski, Marcin;
    • Hou, Cuiping;
    • Frackelton, Edward C;
    • Chiavacci, Rosetta M;
    • Sakurai, Takeshi;
    • Rabin, Cara;
    • Middleton, Frank A
    Publication type:
    Article
    5

    Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy.

    Published in:
    Nature Genetics, 2011, v. 43, n. 7, p. 699, doi. 10.1038/ng.859
    By:
    • Höglinger, Günter U.;
    • Melhem, Nadine M.;
    • Dickson, Dennis W.;
    • Sleiman, Patrick M. A.;
    • Li-San Wang;
    • Klei, Lambertus;
    • Rademakers, Rosa;
    • de Silva, Rohan;
    • Litvan, Irene;
    • Riley, David E.;
    • van Swieten, John C.;
    • Heutink, Peter;
    • Wszolek, Zbigniew K.;
    • Uitti, Ryan J.;
    • Vandrovcova, Jana;
    • Hurtig, Howard I.;
    • Gross, Rachel G.;
    • Maetzler, Walter;
    • Goldwurm, Stefano;
    • Tolosa, Eduardo
    Publication type:
    Article
    6

    Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.

    Published in:
    Nature Genetics, 2010, v. 42, n. 3, p. 234, doi. 10.1038/ng.536
    By:
    • Van Deerlin, Vivianna M.;
    • Sleiman, Patrick M. A.;
    • Martinez-Lage, Maria;
    • Chen-Plotkin, Alice;
    • Li-San Wang;
    • Graff-Radford, Neill R.;
    • Dickson, Dennis W.;
    • Rademakers, Rosa;
    • Boeve, Bradley F.;
    • Grossman, Murray;
    • Arnold, Steven E.;
    • Mann, David M. A.;
    • Pickering-Brown, Stuart M.;
    • Seelaar, Harro;
    • Heutink, Peter;
    • van Swieten, John C.;
    • Murrell, Jill R.;
    • Ghetti, Bernardino;
    • Spina, Salvatore;
    • Grafman, Jordan
    Publication type:
    Article
    7

    Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease.

    Published in:
    Nature Genetics, 2008, v. 40, n. 10, p. 1211, doi. 10.1038/ng.203
    By:
    • Kugathasan, Subra;
    • Baldassano, Robert N.;
    • Bradfield, Jonathan P.;
    • Sleiman, Patrick M. A.;
    • Imielinski, Marcin;
    • Guthery, Stephen L.;
    • Cucchiara, Salvatore;
    • Kim, Cecilia E.;
    • Frackelton, Edward C.;
    • Annaiah, Kiran;
    • Glessner, Joseph T.;
    • Santa, Erin;
    • Willson, Tara;
    • Eckert, Andrew W.;
    • Bonkowski, Erin;
    • Shaner, Julie L.;
    • Smith, Ryan M.;
    • Otieno, F. George;
    • Peterson, Nicholas;
    • Abrams, Debra J.
    Publication type:
    Article
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    UCHL-1 gene in multiple system atrophy: a haplotype tagging approach.

    Published in:
    2005
    By:
    • Healy, Daniel G.;
    • Abou-Sleiman, Patrick M.;
    • Quinn, Niall;
    • Ahmadi, Kourosh R.;
    • Ozawa, Tetsutaro;
    • Kamm, Christoph;
    • Wullner, Ullrich;
    • Oertel, Wolfgang H.;
    • Burk, Katrin;
    • Dupont, Erik;
    • Pellecchia, Maria T.;
    • Tolosa, Eduardo;
    • Gasser, Thomas;
    • Holton, Janice L.;
    • Revesz, Tamas;
    • Goldstein, David B.;
    • Lees, Andrew J.;
    • Wood, Nicholas W.;
    • European MSA Study Group
    Publication type:
    journal article
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    Copy Number Variations in Alternative Splicing Gene Networks Impact Lifespan.

    Published in:
    PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053846
    By:
    • Glessner, Joseph T.;
    • Smith, Albert Vernon;
    • Panossian, Saarene;
    • Kim, Cecilia E.;
    • Takahashi, Nagahide;
    • Thomas, Kelly A.;
    • Fengxiang Wang;
    • Seidler, Kallyn;
    • Harris, Tamara B.;
    • Launer, Lenore J.;
    • Keating, Brendan;
    • Connolly, John;
    • Sleiman, Patrick M. A.;
    • Buxbaum, Joseph D.;
    • Grant, Struan F. A.;
    • Gudnason, Vilmundur;
    • Hakonarson, Hakon
    Publication type:
    Article
    16

    Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder.

    Published in:
    PLoS ONE, 2010, v. 5, n. 12, p. 1, doi. 10.1371/journal.pone.0015463
    By:
    • Glessner, Joseph T.;
    • Kai Wang;
    • Sleiman, Patrick M. A.;
    • Zhang, Haitao;
    • Kim, Cecilia E.;
    • Flory, James H.;
    • Bradfield, Jonathan P.;
    • Imielinski, Marcin;
    • Frackelton, Edward C.;
    • Haijun Qiu;
    • Mentch, Frank;
    • Grant, Struan F. A.;
    • Hakonarson, Hakon
    Publication type:
    Article
    17
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    Trans‐ethnic polygenic risk scores for body mass index: An international hundred K+ cohorts consortium study.

    Published in:
    Clinical & Translational Medicine, 2023, v. 13, n. 6, p. 1, doi. 10.1002/ctm2.1291
    By:
    • Qu, Hui‐Qi;
    • Connolly, John J;
    • Kraft, Peter;
    • Long, Jirong;
    • Pereira, Alexandre;
    • Flatley, Christopher;
    • Turman, Constance;
    • Prins, Bram;
    • Mentch, Frank;
    • Lotufo, Paulo A;
    • Magnus, Per;
    • Stampfer, Meir J;
    • Tamimi, Rulla;
    • Eliassen, A Heather;
    • Zheng, Wei;
    • Knudsen, Gun Peggy Stromstad;
    • Helgeland, Oyvind;
    • Butterworth, Adam S.;
    • Hakonarson, Hakon;
    • Sleiman, Patrick M.
    Publication type:
    Article
    19
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    Trans‐ethnic genomic informed risk assessment for Alzheimer's disease: An International Hundred K+ Cohorts Consortium study.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 12, p. 5765, doi. 10.1002/alz.13378
    By:
    • Sleiman, Patrick M.;
    • Qu, Hui‐Qi;
    • Connolly, John J.;
    • Mentch, Frank;
    • Pereira, Alexandre;
    • Lotufo, Paulo A.;
    • Tollman, Stephen;
    • Choudhury, Ananyo;
    • Ramsay, Michele;
    • Kato, Norihiro;
    • Ozaki, Kouichi;
    • Mitsumori, Risa;
    • Jeon, Jae‐Pil;
    • Hong, Chang Hyung;
    • Son, Sang Joon;
    • Roh, Hyun Woong;
    • Lee, Dong‐gi;
    • Mukadam, Naaheed;
    • Foote, Isabelle F.;
    • Marshall, Charles R.
    Publication type:
    Article
    21
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    Lung Function in African American Children with Asthma Is Associated with Novel Regulatory Variants of the KIT Ligand KITLG/SCF and Gene-By-Air-Pollution Interaction.

    Published in:
    Genetics, 2020, v. 215, n. 3, p. 869, doi. 10.1534/genetics.120.303231
    By:
    • Mak, Angel C. Y.;
    • Sajuthi, Satria;
    • Jaehyun Joo;
    • Shujie Xiao;
    • Sleiman, Patrick M.;
    • White, Marquitta J.;
    • Lee, Eunice Y.;
    • Saef, Benjamin;
    • Donglei Hu;
    • Hongsheng Gui;
    • Keys, Kevin L.;
    • Lurmann, Fred;
    • Jain, Deepti;
    • Abecasis, Gonçalo;
    • Hyun Min Kang;
    • Nickerson, Deborah A.;
    • Germer, Soren;
    • Zody, Michael C.;
    • Winterkorn, Lara;
    • Reeves, Catherine
    Publication type:
    Article
    23
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    COVID-19 in pediatrics: Genetic susceptibility.

    Published in:
    Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.928466
    By:
    • Glessner, Joseph T.;
    • Xiao Chang;
    • Mentch, Frank;
    • Huiqi Qu;
    • Abrams, Debra J.;
    • Thomas, Alexandria;
    • Sleiman, Patrick M. A.;
    • Hakonarson, Hakon
    Publication type:
    Article
    25

    Phenome-wide association studies across large population cohorts support drug target validation.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06540-3
    By:
    • Diogo, Dorothée;
    • Tian, Chao;
    • Franklin, Christopher S.;
    • Alanne-Kinnunen, Mervi;
    • March, Michael;
    • Spencer, Chris C. A.;
    • Vangjeli, Ciara;
    • Weale, Michael E.;
    • Mattsson, Hannele;
    • Kilpeläinen, Elina;
    • Sleiman, Patrick M. A.;
    • Reilly, Dermot F.;
    • McElwee, Joshua;
    • Maranville, Joseph C.;
    • Chatterjee, Arnaub K.;
    • Bhandari, Aman;
    • Nguyen, Khanh-Dung H.;
    • Estrada, Karol;
    • Reeve, Mary-Pat;
    • Hutz, Janna
    Publication type:
    Article
    26
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    Genetic correlations among psychiatric and immune‐related phenotypes based on genome‐wide association data.

    Published in:
    American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2018, v. 177, n. 7, p. 641, doi. 10.1002/ajmg.b.32652
    By:
    • Tylee, Daniel S.;
    • Sun, Jiayin;
    • Hess, Jonathan L.;
    • Tahir, Muhammad A.;
    • Sharma, Esha;
    • Malik, Rainer;
    • Worrall, Bradford B.;
    • Levine, Andrew J.;
    • Martinson, Jeremy J.;
    • Nejentsev, Sergey;
    • Speed, Doug;
    • Fischer, Annegret;
    • Mick, Eric;
    • Walker, Brian R.;
    • Crawford, Andrew;
    • Grant, Struan F. A.;
    • Polychronakos, Constantin;
    • Bradfield, Jonathan P.;
    • Sleiman, Patrick M. A.;
    • Hakonarson, Hakon
    Publication type:
    Article
    28

    Rare recurrent copy number variations in metabotropic glutamate receptor interacting genes in children with neurodevelopmental disorders.

    Published in:
    Journal of Neurodevelopmental Disorders, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s11689-023-09483-z
    By:
    • Glessner, Joseph T.;
    • Khan, Munir E.;
    • Chang, Xiao;
    • Liu, Yichuan;
    • Otieno, F. George;
    • Lemma, Maria;
    • Slaby, Isabella;
    • Hain, Heather;
    • Mentch, Frank;
    • Li, Jin;
    • Kao, Charlly;
    • Sleiman, Patrick M. A.;
    • March, Michael E.;
    • Connolly, John;
    • Hakonarson, Hakon
    Publication type:
    Article
    29
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    A heterozygous effect for PINK1 mutations in Parkinson's disease?

    Published in:
    Annals of Neurology, 2006, v. 60, n. 4, p. 414
    By:
    • Patrick M. Abou‐Sleiman;
    • Miratul M. K. Muqit;
    • Neil Q. McDonald;
    • Yan Xiang Yang;
    • Sonia Gandhi;
    • Daniel G. Healy;
    • Kirsten Harvey;
    • Robert J. Harvey;
    • Emma Deas;
    • Kailash Bhatia;
    • Niall Quinn;
    • Andrew Lees;
    • David S. Latchman;
    • Nicholas W. Wood
    Publication type:
    Article
    31

    UCHL‐1 is not a Parkinson's disease susceptibility gene.

    Published in:
    Annals of Neurology, 2006, v. 59, n. 4, p. 627
    By:
    • Daniel G. Healy;
    • Patrick M. Abou‐Sleiman;
    • Juan P. Casas;
    • Kourosh R. Ahmadi;
    • Timothy Lynch;
    • Sonia Gandhi;
    • Miratul M. K. Muqit;
    • Thomas Foltynie;
    • Roger Barker;
    • Kailash P. Bhatia;
    • Niall P. Quinn;
    • Andrew J. Lees;
    • J. Mark Gibson;
    • Janice L. Holton;
    • Tamas Revesz;
    • David B. Goldstein;
    • Nicholas W. Wood
    Publication type:
    Article
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    The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease.

    Published in:
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2015, v. 11, n. 12, p. 1407, doi. 10.1016/j.jalz.2014.12.009
    By:
    • Lill, Christina M.;
    • Rengmark, Aina;
    • Pihlstrøm, Lasse;
    • Fogh, Isabella;
    • Shatunov, Aleksey;
    • Sleiman, Patrick M.;
    • Wang, Li-San;
    • Liu, Tian;
    • Lassen, Christina F.;
    • Meissner, Esther;
    • Alexopoulos, Panos;
    • Calvo, Andrea;
    • Chio, Adriano;
    • Dizdar, Nil;
    • Faltraco, Frank;
    • Forsgren, Lars;
    • Kirchheiner, Julia;
    • Kurz, Alexander;
    • Larsen, Jan P.;
    • Liebsch, Maria
    Publication type:
    Article
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    NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients.

    Published in:
    Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-22120-4
    By:
    • March, Michael E.;
    • Gutierrez-Uzquiza, Alvaro;
    • Snorradottir, Asbjorg Osk;
    • Matsuoka, Leticia S.;
    • Balvis, Noelia Fonseca;
    • Gestsson, Thorgeir;
    • Nguyen, Kenny;
    • Sleiman, Patrick M. A.;
    • Kao, Charlly;
    • Isaksson, Helgi J.;
    • Bragason, Birkir Thor;
    • Olafsson, Elias;
    • Palsdottir, Astridur;
    • Hakonarson, Hakon
    Publication type:
    Article
    43

    Drug‐resistant epilepsy classified by a phenotyping algorithm associates with NTRK2.

    Published in:
    Acta Neurologica Scandinavica, 2019, v. 140, n. 3, p. 169, doi. 10.1111/ane.13115
    By:
    • Almoguera, Berta;
    • McGinnis, Emily;
    • Abrams, Debra;
    • Vazquez, Lyam;
    • Cederquist, Anna;
    • Sleiman, Patrick M.;
    • Dlugos, Dennis;
    • Hakonarson, Hakon;
    • Cagan, Andrew;
    • Connolly, John;
    • Gainer, Vivian S;
    • Garifallou, James;
    • Kaminski, Courtney;
    • Lee, Yvonne C.;
    • Mafra, Fernanda;
    • Mentch, Frank;
    • Pellegrino, Renata;
    • Qiu, Haijun;
    • Snyder, James;
    • Tian, Lifeng
    Publication type:
    Article
    44

    Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.

    Published in:
    Journal of Neurochemistry, 2006, v. 98, n. 1, p. 156, doi. 10.1111/j.1471-4159.2006.03845.x
    By:
    • Muqit, Miratul M. K.;
    • Abou-Sleiman, Patrick M.;
    • Saurin, Adrian T.;
    • Harvey, Kirsten;
    • Gandhi, Sonia;
    • Deas, Emma;
    • Eaton, Simon;
    • Smith, Martin D. Payne;
    • Venner, Kerrie;
    • Matilla, Antoni;
    • Healy, Daniel G.;
    • Gilks, William P.;
    • Lees, Andrew J.;
    • Holton, Janice;
    • Revesz, Tamas;
    • Parker, Peter J.;
    • Harvey, Robert J.;
    • Wood, Nicholas W.;
    • Latchman, David S.
    Publication type:
    Article
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    BMD-Associated Variation at the Osterix Locus Is Correlated With Childhood Obesity in Females.

    Published in:
    Obesity (19307381), 2011, v. 19, n. 6, p. 1311, doi. 10.1038/oby.2010.324
    By:
    • Jianhua Zhao;
    • Bradfield, Jonathan P.;
    • Mingyao Li;
    • Haitao Zhang;
    • Mentch, Frank D.;
    • Kai Wang;
    • Sleiman, Patrick M. A.;
    • Kim, Cecilia E.;
    • Glessner, Joseph T.;
    • Frackelton, Edward C.;
    • Chiavacci, Rosetta M.;
    • Berkowitz, Robert I.;
    • Zemel, Babette S.;
    • Hakonarson, Hakon;
    • Grant, Struan F. A.
    Publication type:
    Article
    48

    Genome-wide association study for acute otitis media in children identifies FNDC1 as disease contributing gene.

    Published in:
    Nature Communications, 2016, v. 7, n. 9, p. 12792, doi. 10.1038/ncomms12792
    By:
    • van Ingen, Gijs;
    • Li, Jin;
    • Goedegebure, André;
    • Pandey, Rahul;
    • Li, Yun Rose;
    • March, Michael E.;
    • Jaddoe, Vincent W. V.;
    • Bakay, Marina;
    • Mentch, Frank D.;
    • Thomas, Kelly;
    • Wei, Zhi;
    • Chang, Xiao;
    • Hain, Heather S.;
    • Uitterlinden, André G.;
    • Moll, Henriette A.;
    • van Duijn, Cornelia M.;
    • Rivadeneira, Fernando;
    • Raat, Hein;
    • Baatenburg de Jong, Robert J.;
    • Sleiman, Patrick M.
    Publication type:
    Article
    49

    GWAS identifies four novel eosinophilic esophagitis loci.

    Published in:
    Nature Communications, 2014, v. 5, n. 11, p. 5593, doi. 10.1038/ncomms6593
    By:
    • Sleiman, Patrick M. A.;
    • Wang, Mei-Lun;
    • Cianferoni, Antonella;
    • Aceves, Seema;
    • Gonsalves, Nirmala;
    • Nadeau, Kari;
    • Bredenoord, Albert J.;
    • Furuta, Glenn T.;
    • Spergel, Jonathan M.;
    • Hakonarson, Hakon
    Publication type:
    Article
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