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Epigenetic and Metabolomic Biomarkers for Biological Age: A Comparative Analysis of Mortality and Frailty Risk.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 10, p. 1753, doi. 10.1093/gerona/glad137
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- Article
The ApoE ε4 Isoform: Can the Risk of Diseases be Reduced by Environmental Factors?
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- 2019
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- Publication type:
- journal article
Longevity Around the Turn of the 20th Century: Life-Long Sustained Survival Advantage for Parents of Today's Nonagenarians.
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- 2018
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- journal article
Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity.
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- 2017
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- journal article
P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age.
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- 2016
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- journal article
Facial Appearance Reflects Human Familial Longevity and Cardiovascular Disease Risk in Healthy Individuals.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 2, p. 145, doi. 10.1093/gerona/gls154
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- Article
Distinguishing Between Longevity and Buffered-Deleterious Genotypes for Exceptional Human Longevity: The Case of the MTP Gene.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67, n. 11, p. 1153, doi. 10.1093/gerona/gls103
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- Article
Chronic Inhibition of the Respiratory Chain in Human Fibroblast Cultures: Differential Responses Related to Subject Chronological and Biological Age.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2012, v. 67A, n. 5, p. 456, doi. 10.1093/gerona/glr196
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- Article
A Meta-analysis of Four Genome-Wide Association Studies of Survival to Age 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, v. 65A, n. 5, p. 478, doi. 10.1093/gerona/glq028
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- Article
Low Serum Free Triiodothyronine Levels Mark Familial Longevity: The Leiden Longevity Study.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2010, v. 65A, n. 4, p. 365
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- Article
SIRT1 Gene, Age-Related Diseases, and Mortality: The Leiden 85-Plus Study.
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- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 9, p. 960, doi. 10.1093/gerona/62.9.960
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- Article
Liver X Receptor Alpha Associates With Human Life Span.
- Published in:
- Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2007, v. 62, n. 4, p. 343, doi. 10.1093/gerona/62.4.343
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- Publication type:
- Article
Cerebral Microbleeds and Lacunar Infarcts Are Associated with Walking Speed Independent of Cognitive Performance in Middle-Aged to Older Adults.
- Published in:
- 2016
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- Publication type:
- journal article
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-022-35663-x
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- Publication type:
- Article
Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response.
- Published in:
- Nature Communications, 2023, v. 14, p. 1, doi. 10.1038/s41467-022-35663-x
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- Publication type:
- Article
Survival analysis with delayed entry in selected families with application to human longevity.
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- 2018
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- Publication type:
- journal article
Alzheimer's disease plasma markers and depressive symptoms: an IPD meta‐analysis.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079693
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- Article
Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects.
- Published in:
- 2019
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- journal article
Functional Changes of T-Cell Subsets with Age and CMV Infection.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 18, p. 9973, doi. 10.3390/ijms22189973
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- Publication type:
- Article
Clarifying the biological and statistical assumptions of cross-sectional biological age predictors: an elaborate illustration using synthetic and real data.
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- BMC Medical Research Methodology, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12874-024-02181-x
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- Article
The Dynamics of Genome Organization and Expression during the Aging Process.
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- Annals of the New York Academy of Sciences, 1992, v. 673, n. 1, p. 58, doi. 10.1111/j.1749-6632.1992.tb27437.x
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- Article
DNA Processing, Aging, and Cancer.
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- Annals of the New York Academy of Sciences, 1991, v. 621, n. 1, p. 53, doi. 10.1111/j.1749-6632.1991.tb16968.x
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- Article
The Leiden Family Lab study on Social Anxiety Disorder: A multiplex, multigenerational family study on neurocognitive endophenotypes.
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- International Journal of Methods in Psychiatric Research, 2018, v. 27, n. 2, p. 1, doi. 10.1002/mpr.1616
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- Article
A recurrent neural network architecture to model physical activity energy expenditure in older people.
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- Data Mining & Knowledge Discovery, 2022, v. 36, n. 1, p. 477, doi. 10.1007/s10618-021-00817-w
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- Article
Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health's 1 H-NMR Metabolomics Platform.
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- Metabolites (2218-1989), 2023, v. 13, n. 12, p. 1181, doi. 10.3390/metabo13121181
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- Article
Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data.
- Published in:
- 2020
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- Publication type:
- journal article
Establishing a Twin Register: An Invaluable Resource for (Behavior) Genetic, Epidemiological, Biomarker, and 'Omics' Studies.
- Published in:
- 2018
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- Publication type:
- journal article
Familial Resemblance for Serum Metabolite Concentrations.
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- Twin Research & Human Genetics, 2013, v. 16, n. 5, p. 948, doi. 10.1017/thg.2013.59
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- Article
Familial Resemblance for Serum Metabolite Concentrations — Corrigendum.
- Published in:
- 2013
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- Correction Notice
The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection.
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- Twin Research & Human Genetics, 2013, v. 16, n. 1, p. 271, doi. 10.1017/thg.2012.140
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- Publication type:
- Article
The serotonin transporter gene length polymorphism (5-HTTLPR) and life events: no evidence for an interaction effect on neuroticism and anxious depressive symptoms.
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- 2010
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- Publication type:
- journal article
The Netherlands Twin Register biobank: a resource for genetic epidemiological studies.
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- 2010
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- journal article
Vitamin D receptor gene polymorphisms have negligible effect on human height.
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- 2008
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- Publication type:
- journal article
Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age.
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- Frontiers in Aging Neuroscience, 2015, v. 7, p. 1, doi. 10.3389/fnagi.2015.00092
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- Article
Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction.
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- EMBO Journal, 2019, v. 38, n. 23, p. N.PAG, doi. 10.15252/embj.2019101982
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- Article
Genome-wide patterns and properties of de novo mutations in humans.
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- Nature Genetics, 2015, v. 47, n. 7, p. 822, doi. 10.1038/ng.3292
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- Article
The impact of low-frequency and rare variants on lipid levels.
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- Nature Genetics, 2015, v. 47, n. 6, p. 589, doi. 10.1038/ng.3300
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- Article
Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship.
- Published in:
- 2015
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- Publication type:
- journal article
Abdominal Fat Accumulation in Adults Born Preterm Exposed Antenatally to Maternal Glucocorticoid Treatment Is Dependent on Glucocorticoid Receptor Gene Variation.
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- Journal of Clinical Endocrinology & Metabolism, 2011, v. 96, n. 10, p. E1650, doi. 10.1210/jc.2011-0288
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- Article
Genetic variants in the glucocorticoid receptor gene ( NR3C1) and cardiovascular disease risk. The Leiden 85-plus Study.
- Published in:
- Biogerontology, 2006, v. 7, n. 4, p. 231, doi. 10.1007/s10522-006-9021-2
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- Publication type:
- Article
Validated inference of smoking habits from blood with a finite DNA methylation marker set.
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- European Journal of Epidemiology, 2019, v. 34, n. 11, p. 1055, doi. 10.1007/s10654-019-00555-w
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- Publication type:
- Article
Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice.
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- Scientific Reports, 2017, p. 43261, doi. 10.1038/srep43261
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- Article
The effect of standardized food intake on the association between BMI and <sup>1</sup>H-NMR metabolites.
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- Scientific Reports, 2016, p. 38980, doi. 10.1038/srep38980
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- Publication type:
- Article
Increasing number of long-lived ancestors marks a decade of healthspan extension and healthier metabolomics profiles.
- Published in:
- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-40245-6
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- Publication type:
- Article
Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome.
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- Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01578-7
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- Publication type:
- Article
Validating biomarkers and models for epigenetic inference of alcohol consumption from blood.
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- Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01186-3
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- Article
Validating biomarkers and models for epigenetic inference of alcohol consumption from blood.
- Published in:
- Clinical Epigenetics, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13148-021-01186-3
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- Publication type:
- Article
Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression.
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- Genome Biology, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s13059-021-02585-8
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- Article
Genes Involved in the Osteoarthritis Process Identified through Genome Wide Expression Analysis in Articular Cartilage; the RAAK Study.
- Published in:
- PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0103056
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- Article
Association of Liver Enzymes and Computed Tomography Markers of Liver Steatosis with Familial Longevity.
- Published in:
- PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091085
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- Publication type:
- Article