Works by Skehel, Paul A.

Results: 22

Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability.

Published in:

Cells (2073-4409), 2021, v. 10, n. 12, p. 3403, doi. 10.3390/cells10123403

By:

Graham, Laura C.;
Kline, Rachel A.;
Lamont, Douglas J.;
Gillingwater, Thomas H.;
Mabbott, Neil A.;
Skehel, Paul A.;
Wishart, Thomas M.

Publication type:

Article

Extracellular Localisation of the C-Terminus of DDX4 Confirmed by Immunocytochemistry and Fluorescence-Activated Cell Sorting.

Published in:

Cells (2073-4409), 2019, v. 8, n. 6, p. 578, doi. 10.3390/cells8060578

By:

Clarkson, Yvonne L.;
Weatherall, Emma;
Waterfall, Martin;
McLaughlin, Marie;
Lu, Haojiang;
Skehel, Paul A.;
Anderson, Richard A.;
Telfer, Evelyn E.

Publication type:

Article

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 4, p. 1821, doi. 10.1172/JCI71318

By:

Wishart, Thomas M.;
Mutsaers, Chantal A.;
Riessland, Markus;
Reimer, Michell M.;
Hunter, Gillian;
Hannam, Marie L.;
Eaton, Samantha L.;
Fuller, Heidi R.;
Roche, Sarah L.;
Somers, Eilidh;
Morse, Robert;
Young, Philip J.;
Lamont, Douglas J.;
Hammerschmidt, Matthias;
Joshi, Anagha;
Hohenstein, Peter;
Morris, Glenn E.;
Parson, Simon H.;
Skehel, Paul A.;
Becker, Thomas

Publication type:

Article

The human NMDA receptor GluN2A<sup>N615K</sup> variant influences channel blocker potency.

Published in:

Pharmacology Research & Perspectives, 2019, v. 7, n. 4, p. N.PAG, doi. 10.1002/prp2.495

By:

Marwick, Katie F. M.;
Skehel, Paul A.;
Hardingham, Giles E.;
Wyllie, David J. A.

Publication type:

Article

Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture.

Published in:

Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0221-9

By:

Graham, Laura C.;
Eaton, Samantha L.;
Brunton, Paula J.;
Atrih, Abdelmadjid;
Smith, Colin;
Lamont, Douglas J.;
Gillingwater, Thomas H.;
Pennetta, Giuseppa;
Skehel, Paul;
Wishart, Thomas M.

Publication type:

Article

VAPB interacts with and modulates the activity of ATF6.

Published in:

Human Molecular Genetics, 2008, v. 17, n. 11, p. 1517, doi. 10.1093/hmg/ddn040

By:

Gkogkas, Christos;
Middleton, Susan;
Kremer, Anna M.;
Wardrope, Caroline;
Hannah, Matthew;
Gillingwater, Thomas H.;
Skehel, Paul

Publication type:

Article

The neuroprotective WldS gene regulates expression of PTTG1 and erythroid differentiation regulator 1-like gene in mice and human cells.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 4, p. 625, doi. 10.1093/hmg/ddi478

By:

Gillingwater, Thomas H.;
Wishart, Thomas M.;
Chen, Philip E.;
Haley, Jane E.;
Robertson, Kevin;
MacDonald, Stephen H.-F.;
Middleton, Susan;
Wawrowski, Kolja;
Shipston, Michael J.;
Melmed, Shlomo;
Wyllie, David J.A.;
Skehel, Paul A.;
Coleman, Michael P.;
Ribchester, Richard R.

Publication type:

Article

A Tri-Hybrid System for the Analysis and Detection of RNA-Protein Interactions.

Published in:

Nucleic Acids Research, 1996, v. 24, n. 23, p. 4838, doi. 10.1093/nar/24.23.4838

By:

Putz, Ulrich;
Skehel, Paul;
Kuhl, Dietmar

Publication type:

Article

Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy.

Published in:

Journal of Physiology, 2019, v. 597, n. 6, p. 1691, doi. 10.1113/JP277292

By:

Marwick, Katie F. M.;
Hansen, Kasper B.;
Skehel, Paul A.;
Hardingham, Giles E.;
Wyllie, David J. A.

Publication type:

Article

Confocal Endomicroscopy of Neuromuscular Junctions Stained with Physiologically Inert Protein Fragments of Tetanus Toxin.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 10, p. 1499, doi. 10.3390/biom11101499

By:

Roesl, Cornelia;
Evans, Elizabeth R.;
Dissanayake, Kosala N.;
Boczonadi, Veronika;
Jones, Ross A.;
Jordan, Graeme R.;
Ledahawsky, Leire;
Allen, Guy C. C.;
Scott, Molly;
Thomson, Alanna;
Wishart, Thomas M.;
Hughes, David I.;
Mead, Richard J.;
Shone, Clifford C.;
Slater, Clarke R.;
Gillingwater, Thomas H.;
Skehel, Paul A.;
Ribchester, Richard R.

Publication type:

Article

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.

Published in:

Nature Communications, 2013, v. 4, n. 6, p. 2034, doi. 10.1038/ncomms3034

By:

Qiu, Jing;
Tan, Yan-Wei;
Hagenston, Anna M.;
Martel, Marc-Andre;
Kneisel, Niclas;
Skehel, Paul A.;
Wyllie, David J. A.;
Bading, Hilmar;
Hardingham, Giles E.

Publication type:

Article

CLICK: one-step generation of conditional knockout mice.

Published in:

BMC Genomics, 2018, v. 19, n. 1, p. 1, doi. 10.1186/s12864-018-4713-y

By:

Yoshiki Miyasaka;
Yoshihiro Uno;
Kazuto Yoshimi;
Yayoi Kunihiro;
Takuji Yoshimura;
Tomohiro Tanaka;
Harumi Ishikubo;
Yuichi Hiraoka;
Norihiko Takemoto;
Takao Tanaka;
Yoshihiro Ooguchi;
Skehel, Paul;
Tomomi Aida;
Junji Takeda;
Tomoji Mashimo

Publication type:

Article

GRIN2A-related disorders: genotype and functional consequence predict phenotype.

Published in:

2019

By:

Strehlow, Vincent;
Heyne, Henrike O;
Vlaskamp, Danique R M;
Marwick, Katie F M;
Rudolf, Gabrielle;
Bellescize, Julitta de;
Biskup, Saskia;
Brilstra, Eva H;
Brouwer, Oebele F;
Callenbach, Petra M C;
Hentschel, Julia;
Hirsch, Edouard;
Kind, Peter C;
Mignot, Cyril;
Platzer, Konrad;
Rump, Patrick;
Skehel, Paul A;
Wyllie, David J A;
Hardingham, Giles E;
Ravenswaaij-Arts, Conny M A van

Publication type:

journal article

De novo point mutations in patients diagnosed with ataxic cerebral palsy.

Published in:

2015

By:

Schnekenberg, Ricardo Parolin;
Perkins, Emma M.;
Miller, Jack W.;
Davies, Wayne I. L.;
D'Adamo, Maria Cristina;
Pessia, Mauro;
Fawcett, Katherine A.;
Sims, David;
Gillard, Elodie;
Hudspith, Karl;
Skehel, Paul;
Williams, Jonathan;
O'Regan, Mary;
Jayawant, Sandeep;
Jefferson, Rosalind;
Hughes, Sarah;
Lustenberger, Andrea;
Ragoussis, Jiannis;
Jackson, Mandy;
Tucker, Stephen J.

Publication type:

journal article

A Dictyostelium nuclear phosphatidylinositol phosphate kinase required for developmental gene expression.

Published in:

EMBO Journal, 2001, v. 20, n. 21, p. 6017, doi. 10.1093/emboj/20.21.6017

By:

Guo, Kunde;
Nichol, Richard;
Skehel, Paul;
Dormann, Dirk;
Weijer, Cornelis J.;
Williams, Jeffrey G.;
Pears, Catherine

Publication type:

Article

SMRT-mediated co-shuttling enables export of class IIa HDACs independent of their CaM kinase phosphorylation sites.

Published in:

Journal of Neurochemistry, 2013, v. 124, n. 1, p. 26, doi. 10.1111/jnc.12058

By:

Soriano, Francesc X.;
Chawla, Sangeeta;
Skehel, Paul;
Hardingham, Giles E.

Publication type:

Article

The ALS8-associated mutant VAPB.

Published in:

Journal of Neurochemistry, 2011, v. 117, n. 2, p. 286, doi. 10.1111/j.1471-4159.2011.07201.x

By:

Gkogkas, Christos;
Wardrope, Caroline;
Hannah, Matthew;
Skehel, Paul

Publication type:

Article

Endomicroscopy and electromyography of neuromuscular junctions in situ.

Published in:

Annals of Clinical & Translational Neurology, 2014, v. 1, n. 11, p. 867, doi. 10.1002/acn3.124

By:

Brown, Rosalind;
Dissanayake, Kosala N.;
Skehel, Paul A.;
Ribchester, Richard R

Publication type:

Article

P.07: In-vitro models utilised to enhance our understanding of early mechanisms of misfolded protein formation, accumulation and clearance.

Published in:

Prion, 2014, v. 8, p. 27

By:

Manson, Jean C.;
King, Declan;
Skehel, Paul;
Barron, Rona M.

Publication type:

Article

Spinal cord neurone loss and foot placement changes in a rat knock-in model of amyotrophic lateral sclerosis Type 8.

Published in:

Brain Communications, 2024, v. 6, n. 3, p. 1, doi. 10.1093/braincomms/fcae184

By:

Murage, Brenda;
Tan, Han;
Mashimo, Tomoji;
Jackson, Mandy;
Skehel, Paul A

Publication type:

Article

Microarray profiling emphasizes transcriptomic differences between hippocampal in vivo tissue and in vitro cultures.

Published in:

Brain Communications, 2021, v. 3, n. 3, p. 1, doi. 10.1093/braincomms/fcab152

By:

King, Declan;
Skehel, Paul A.;
Dando, Owen;
Emelianova, Katie;
Barron, Rona;
Wishart, Thomas M.

Publication type:

Article

β-III spectrin underpins ankyrin R function in Purkinje cell dendritic trees: protein complex critical for sodium channel activity is impaired by SCA5-associated mutations.

Published in:

Human Molecular Genetics, 2014, v. 23, n. 14, p. 3875, doi. 10.1093/hmg/ddu103

By:

Clarkson, Yvonne L.;
Perkins, Emma M.;
Cairncross, Callum J.;
Lyndon, Alastair R.;
Skehel, Paul A.;
Jackson, Mandy

Publication type:

Article