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Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels.
Published in:
EMBO Journal, 2006, v. 25, n. 17, p. 4142, doi. 10.1038/sj.emboj.7601275
By:
- Mankouri, Jamel;
- Taneja, Tarvinder K.;
- Smith, Andrew J.;
- Ponnambalam, Sreenivasan;
- Sivaprasadarao, Asipu
Publication type:
Article
Molecular mechanism of voltage sensor movements in a potassium channel.
Published in:
EMBO Journal, 2004, v. 23, n. 24, p. 4717, doi. 10.1038/sj.emboj.7600484
By:
- Elliott, David JS;
- Neale, Edward J;
- Aziz, Qadeer;
- Dunham, James P;
- Munsey, Tim S;
- Hunter, Malcolm;
- Sivaprasadarao, Asipu
Publication type:
Article
TRPM2-mediated intracellular Zn2+ release triggers pancreatic β-cell death.
Published in:
Biochemical Journal, 2015, v. 466, n. 3, p. 537, doi. 10.1042/BJ20140747
By:
- Manna, Paul T.;
- Munsey, Tim S.;
- Abuarab, Nada;
- Fangfang Li;
- Asipu, Aruna;
- Howell, Gareth;
- Sedo, Alicia;
- Wei Yang;
- Naylor, Jacqui;
- Beech, David J.;
- Lin-Hua Jiang;
- Sivaprasadarao, Asipu
Publication type:
Article
Selectivity and interactions of Ba2+ and Cs+ with wild-type and mutant TASK1 K+ channels expressed inXenopusoocytes.
Published in:
Journal of Physiology, 2005, v. 562, n. 3, p. 687, doi. 10.1113/jphysiol.2004.079020
By:
- O'Connell, Anthony D.;
- Morton, Michael J.;
- Sivaprasadarao, Asipu;
- Hunter, Malcolm
Publication type:
Article
Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle.
Published in:
Journal of Physiology, 2004, v. 556, n. 1, p. 29, doi. 10.1113/jphysiol.2003.058594
By:
- Fountain, S. J.;
- Cheong, A.;
- Flemming, R.;
- Mair, L.;
- Sivaprasadarao, A.;
- Beech, D. J.
Publication type:
Article
Inhibition of the K+ channel Kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation.
Published in:
Journal of Physiology, 2000, v. 526, n. 2, p. 253, doi. 10.1111/j.1469-7793.2000.00253.x
By:
- Claydon, T. W.;
- Boyett, M. R.;
- Sivaprasadarao, A.;
- Ishii, K.;
- Owen, J. M.;
- O'Beirne, H. A.;
- Leach, R.;
- Komukai, K.;
- Orchard, C. H.
Publication type:
Article
Effect of cysteine substitutions on the topology of the S4 segment of the Shaker potassium channel: implications for molecular models of gating.
Published in:
Journal of Physiology, 1999, v. 521, n. 2, p. 315, doi. 10.1111/j.1469-7793.1999.00315.x
By:
- Wang, M.-H.;
- Yusaf, S. P.;
- Elliott, D. J. S.;
- Wray, D.;
- Sivaprasadarao, A.
Publication type:
Article
Block of human aorta Kir6.1 by the vascular KATP channel inhibitor U37883A.
Published in:
British Journal of Pharmacology, 1999, v. 128, n. 3, p. 667, doi. 10.1038/sj.bjp.0702862
By:
- Surah-Narwal, S;
- Xu, S Z;
- McHugh, D;
- McDonald, R L;
- Hough, E;
- Cheong, A;
- Partridge, C;
- Sivaprasadarao, A;
- Beech, D J
Publication type:
Article
Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.
Published in:
1997
By:
- Gould, J;
- Morton, M J;
- Sivaprasadarao, A;
- Bowmer, C J;
- Yates, M S
Publication type:
journal article
Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.
Published in:
British Journal of Pharmacology, 1997, v. 120, n. 5, p. 947, doi. 10.1038/sj.bjp.0700980
By:
- Gould, J;
- Morton, M J;
- Sivaprasadarao, A;
- Bowmer, C J;
- Yates, M S
Publication type:
Article
High glucose--induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn2+-mediated mitochondrial fission.
Published in:
Science Signaling, 2017, v. 10, n. 490, p. 1, doi. 10.1126/scisignal.aal4161
By:
- Abuarab, Nada;
- Munsey, Tim S.;
- Lin-Hua Jiang;
- Jing Li;
- Sivaprasadarao, Asipu
Publication type:
Article
Generation of functional ion-channel tools by E3 targeting.
Published in:
Nature Biotechnology, 2005, v. 23, n. 10, p. 1289, doi. 10.1038/nbt1148
By:
- Shang-Zhong Xu;
- Fanning Zeng;
- Ming Lei;
- Jing Li;
- Bin Gao;
- Chenliang Xiong;
- Sivaprasadarao, Asipu;
- Beech, David J.
Publication type:
Article
Endocytosis of hERG Is Clathrin-Independent and Involves Arf6.
Published in:
PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0085630
By:
- Karnik, Rucha;
- Ludlow, Melanie J.;
- Abuarab, Nada;
- Smith, Andrew J.;
- Hardy, Matthew E. L.;
- Elliott, David J. S.;
- Sivaprasadarao, Asipu
Publication type:
Article
Hyperinsulinemic Hypoglycemia in Beckwith-Wiedemann Syndrome due to Defects in the Function of Pancreatic β-Cell Adenosine Triphosphate-Sensitive Potassium Channels.
Published in:
2005
By:
- Hussain, K.;
- Cosgrove, K. E.;
- Shepherd, R. M.;
- Luharia, A.;
- Smith, V. V.;
- Kassem, S.;
- Gregory, J. W.;
- Sivaprasadarao, A.;
- Christesen, H. T.;
- Jacobsen, B. B.;
- Brusgaard, K.;
- Glaser, B.;
- Maher, E. A.;
- Lindley, K. J.;
- Hindmarsh, P.;
- Dattani, M.;
- Dunne, M. J.
Publication type:
journal article
NOX2-TRPM2 coupling promotes Zn2+ inhibition of complex III to exacerbate ROS production in a cellular model of Parkinson's disease.
Published in:
Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66630-9
By:
- AlAhmad, Maali;
- Isbea, Hala;
- Shitaw, Esra;
- Li, Fangfang;
- Sivaprasadarao, Asipu
Publication type:
Article
Determinants of pH sensing in the two-pore domain K+ channels TASK-1 and -2.
Published in:
Pflügers Archiv: European Journal of Physiology, 2003, v. 445, n. 5, p. 577, doi. 10.1007/s00424-002-0901-2
By:
- Morton, Michael J.;
- O'Connell, Anthony D.;
- Sivaprasadarao, Asipu;
- Hunter, Malcolm
Publication type:
Article
Identification of molecular regions responsible for the membrane trafficking of Kir6.2.
Published in:
Pflügers Archiv: European Journal of Physiology, 2000, v. 440, n. 3, p. 481, doi. 10.1007/s004240000311
By:
- Hough, E.;
- Beech, D.J.;
- Sivaprasadarao, A.
Publication type:
Article
TRPC channel activation by extracellular thioredoxin.
Published in:
Nature, 2008, v. 451, n. 7174, p. 69, doi. 10.1038/nature06414
By:
- Xu, Shang-Zhong;
- Sukumar, Piruthivi;
- Zeng, Fanning;
- Li, Jing;
- Jairaman, Amit;
- English, Anne;
- Naylor, Jacqueline;
- Ciurtin, Coziana;
- Majeed, Yasser;
- Milligan, Carol J.;
- Bahnasi, Yahya M.;
- Al-Shawaf, Eman;
- Porter, Karen E.;
- Jiang, Lin-Hua;
- Emery, Paul;
- Sivaprasadarao, Asipu;
- Beech, David J.
Publication type:
Article
A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris.
Published in:
Scientific Reports, 2014, p. 1, doi. 10.1038/srep04201
By:
- Dhillon, Mandeep S.;
- Cockcroft, Christopher J.;
- Munsey, Tim;
- Smith, Kathrine J.;
- Powell, Andrew J.;
- Carter, Paul;
- Wrighton, David C.;
- Rong, Hong-lin;
- Yusaf, Shahnaz P.;
- Sivaprasadarao, Asipu
Publication type:
Article
Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation.
Published in:
Cells (2073-4409), 2014, v. 3, n. 2, p. 363, doi. 10.3390/cells3020363
By:
- Jopling, Helen M.;
- Odell, Adam F.;
- Pellet-Many, Caroline;
- Latham, Antony M.;
- Frankel, Paul;
- Sivaprasadarao, Asipu;
- Walker, John H.;
- Zachary, Ian C.;
- Ponnambalam, Sreenivasan
Publication type:
Article
Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism.
Published in:
Human Molecular Genetics, 2009, v. 18, n. 13, p. 2400, doi. 10.1093/hmg/ddp179
By:
- Taneja, Tarvinder K.;
- Mankouri, Jamel;
- Karnik, Rucha;
- Kannan, Soundarapandian;
- Smith, Andrew J.;
- Munsey, Tim;
- Christesen, Henrik B.T.;
- Beech, David J.;
- Sivaprasadarao, Asipu
Publication type:
Article
Activation of the Cl- Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP3 Receptor.
Published in:
Science Signaling, 2013, v. 6, n. 290, p. 1, doi. 10.1126/scisignal.2004184
By:
- Xin Jin;
- Shihab Shah;
- Yani Liu;
- Huiran Zhang;
- Lees, Meredith;
- Zhaojun Fu;
- Lippiat, Jonathan D.;
- Beech, David J.;
- Sivaprasadarao, Asipu;
- Baldwin, Stephen A.;
- Hailin Zhang;
- Gamper, Nikita
Publication type:
Article

Found: 22

Kir6.2 mutations causing neonatal diabetes prevent endocytosis of ATP-sensitive potassium channels.

Molecular mechanism of voltage sensor movements in a potassium channel.

TRPM2-mediated intracellular Zn<sup>2+</sup> release triggers pancreatic β-cell death.

Selectivity and interactions of Ba<sup>2+</sup> and Cs<sup>+</sup> with wild-type and mutant TASK1 K<sup>+</sup> channels expressed inXenopusoocytes.

Functional up-regulation of KCNA gene family expression in murine mesenteric resistance artery smooth muscle.

Inhibition of the K<sup>+</sup> channel Kv1.4 by acidosis: protonation of an extracellular histidine slows the recovery from N-type inactivation.

Effect of cysteine substitutions on the topology of the S4 segment of the Shaker potassium channel: implications for molecular models of gating.

Block of human aorta Kir6.1 by the vascular K<sub>ATP</sub> channel inhibitor U37883A.

Renal adenosine A1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.

Renal adenosine A<sub>1</sub> receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat.

High glucose--induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn<sup>2+</sup>-mediated mitochondrial fission.

Generation of functional ion-channel tools by E3 targeting.

Endocytosis of hERG Is Clathrin-Independent and Involves Arf6.

Hyperinsulinemic Hypoglycemia in Beckwith-Wiedemann Syndrome due to Defects in the Function of Pancreatic β-Cell Adenosine Triphosphate-Sensitive Potassium Channels.

NOX2-TRPM2 coupling promotes Zn<sup>2+</sup> inhibition of complex III to exacerbate ROS production in a cellular model of Parkinson's disease.

Determinants of pH sensing in the two-pore domain K<sup>+</sup> channels TASK-1 and -2.

Identification of molecular regions responsible for the membrane trafficking of Kir6.2.

TRPC channel activation by extracellular thioredoxin.

A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris.

Endosome-to-Plasma Membrane Recycling of VEGFR2 Receptor Tyrosine Kinase Regulates Endothelial Function and Blood Vessel Formation.

Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism.

Activation of the Cl<sup>-</sup> Channel ANO1 by Localized Calcium Signals in Nociceptive Sensory Neurons Requires Coupling with the IP<sub>3</sub> Receptor.