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Nerve Fibers in the Tumor Microenvironment Are Co-Localized with Lymphoid Aggregates in Pancreatic Cancer.
Published in:
Journal of Clinical Medicine, 2021, v. 10, n. 3, p. 490, doi. 10.3390/jcm10030490
By:
- Heij, Lara R.;
- Tan, Xiuxiang;
- Kather, Jakob N.;
- Niehues, Jan M.;
- Sivakumar, Shivan;
- Heussen, Nicole;
- van der Kroft, Gregory;
- Damink, Steven W. M. Olde;
- Lang, Sven;
- Aberle, Merel R.;
- Luedde, Tom;
- Gaisa, Nadine T.;
- Bednarsch, Jan;
- Liu, Drolaiz H. W.;
- Cleutjens, Jack P. M.;
- Modest, Dominik P.;
- Neumann, Ulf P.;
- Wiltberger, Georg J.;
- Nunez, Maria Del Pilar Acedo
Publication type:
Article
The COVID-19 Pandemic Is Associated with Reduced Survival after Pancreatic Ductal Adenocarcinoma Diagnosis: A Single-Centre Retrospective Analysis.
Published in:
Journal of Clinical Medicine, 2022, v. 11, n. 9, p. 2574, doi. 10.3390/jcm11092574
By:
- Madge, Oliver;
- Brodey, Alexandra;
- Bowen, Jordan;
- Nicholson, George;
- Sivakumar, Shivan;
- Bottomley, Matthew J.
Publication type:
Article
Advances in Immunotherapeutics in Pancreatic Ductal Adenocarcinoma.
Published in:
Cancers, 2023, v. 15, n. 17, p. 4265, doi. 10.3390/cancers15174265
By:
- Chouari, Tarak;
- La Costa, Francesca Soraya;
- Merali, Nabeel;
- Jessel, Maria-Danae;
- Sivakumar, Shivan;
- Annels, Nicola;
- Frampton, Adam E.
Publication type:
Article
The Presence of Small Nerve Fibers in the Tumor Microenvironment as Predictive Biomarker of Oncological Outcome Following Partial Hepatectomy for Intrahepatic Cholangiocarcinoma.
Published in:
Cancers, 2021, v. 13, n. 15, p. 3661, doi. 10.3390/cancers13153661
By:
- Bednarsch, Jan;
- Tan, Xiuxiang;
- Czigany, Zoltan;
- Liu, Dong;
- Lang, Sven Arke;
- Sivakumar, Shivan;
- Kather, Jakob Nikolas;
- Appinger, Simone;
- Rosin, Mika;
- Boroojerdi, Shiva;
- Dahl, Edgar;
- Gaisa, Nadine Therese;
- den Dulk, Marcel;
- Coolsen, Mariëlle;
- Ulmer, Tom Florian;
- Neumann, Ulf Peter;
- Heij, Lara Rosaline
Publication type:
Article
Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer.
Published in:
Cancers, 2021, v. 13, n. 8, p. 1776, doi. 10.3390/cancers13081776
By:
- Sivakumar, Shivan;
- Abu-Shah, Enas;
- Ahern, David J.;
- Arbe-Barnes, Edward H.;
- Jainarayanan, Ashwin K.;
- Mangal, Nagina;
- Reddy, Srikanth;
- Rendek, Aniko;
- Easton, Alistair;
- Kurz, Elke;
- Silva, Michael;
- Soonawalla, Zahir;
- Heij, Lara R.;
- Bashford-Rogers, Rachael;
- Middleton, Mark R.;
- Dustin, Michael L.;
- Hiraoka, Nobuyoshi
Publication type:
Article
Circulating Cell-Free Tumour DNA for Early Detection of Pancreatic Cancer.
Published in:
Cancers, 2020, v. 12, n. 12, p. 3704, doi. 10.3390/cancers12123704
By:
- Jaworski, Jedrzej J.;
- Morgan, Robert D.;
- Sivakumar, Shivan
Publication type:
Article
Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound.
Published in:
BMC Cancer, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12885-023-11228-z
By:
- Spiers, Laura;
- Gray, Michael;
- Lyon, Paul;
- Sivakumar, Shivan;
- Bekkali, Noor;
- Scott, Shaun;
- Collins, Linda;
- Carlisle, Robert;
- Wu, Feng;
- Middleton, Mark;
- Coussios, Constantin
Publication type:
Article
Nerve Fibers in the Tumor Microenvironment as a Novel Biomarker for Oncological Outcome in Patients Undergoing Surgery for Perihilar Cholangiocarcinoma.
Published in:
Liver Cancer (2235-1795), 2021, v. 10, n. 3, p. 260, doi. 10.1159/000515303
By:
- Bednarsch, Jan;
- Kather, Jakob;
- Tan, Xiuxiang;
- Sivakumar, Shivan;
- Cacchi, Claudio;
- Wiltberger, Georg;
- Czigany, Zoltan;
- Ulmer, Florian;
- Neumann, Ulf Peter;
- Heij, Lara Rosaline
Publication type:
Article
ToxNav germline genetic testing and PROMinet digital mobile application toxicity monitoring: Results of a prospective single‐center clinical utility study—PRECISE study.
Published in:
Cancer Medicine, 2019, v. 8, n. 14, p. 6305, doi. 10.1002/cam4.2529
By:
- Lee, Lennard Y. W.;
- Starkey, Thomas;
- Sivakumar, Shivan;
- Fotheringham, Susan;
- Mozolowski, Guy;
- Shearwood, Vanessa;
- Palles, Claire;
- Camilleri, Philip;
- Church, David;
- Kerr, Rachel;
- Kerr, David
Publication type:
Article
Improving early diagnosis of pancreatic cancer in symptomatic patients.
Published in:
British Journal of General Practice, 2023, v. 73, n. 737, p. 534, doi. 10.3399/bjgp23x735585
By:
- Johnston, Amber J;
- Sivakumar, Shivan;
- Zhou, Yin;
- Funston, Garth;
- Bradley, Stephen H
Publication type:
Article
Immunophenotypes of pancreatic ductal adenocarcinoma: Meta‐analysis of transcriptional subtypes.
Published in:
International Journal of Cancer, 2019, v. 145, n. 4, p. 1125, doi. 10.1002/ijc.32186
By:
- Santiago, Ines;
- Yau, Christopher;
- Heij, Lara;
- Middleton, Mark R.;
- Markowetz, Florian;
- Grabsch, Heike I.;
- Dustin, Michael L.;
- Sivakumar, Shivan
Publication type:
Article
Unlocking the diagnostic power of plasma extracellular vesicle miR-200 family in pancreatic ductal adenocarcinoma.
Published in:
Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-03090-z
By:
- Liu, Daniel S.K.;
- Puik, Jisce R.;
- Patel, Bhavik Y.;
- Venø, Morten T.;
- Vahabi, Mahrou;
- Prado, Mireia Mato;
- Webber, Jason P.;
- Rees, Eleanor;
- Upton, Flora M.;
- Bennett, Kate;
- Blaker, Catherine;
- Immordino, Benoit;
- Comandatore, Annalisa;
- Morelli, Luca;
- Sivakumar, Shivan;
- Swijnenburg, Rutger-Jan;
- Besselink, Marc G.;
- Jiao, Long R.;
- Kazemier, Geert;
- Giovannetti, Elisa
Publication type:
Article
Predicting the risk of pancreatic cancer in adults with new-onset diabetes: development and internal–external validation of a clinical risk prediction model.
Published in:
British Journal of Cancer, 2024, v. 130, n. 12, p. 1969, doi. 10.1038/s41416-024-02693-9
By:
- Clift, Ash Kieran;
- Tan, Pui San;
- Patone, Martina;
- Liao, Weiqi;
- Coupland, Carol;
- Bashford-Rogers, Rachael;
- Sivakumar, Shivan;
- Hippisley-Cox, Julia
Publication type:
Article
Biomarkers of response to PD-1 pathway blockade.
Published in:
British Journal of Cancer, 2022, v. 126, n. 12, p. 1663, doi. 10.1038/s41416-022-01743-4
By:
- Li, Hanxiao;
- van der Merwe, P. Anton;
- Sivakumar, Shivan
Publication type:
Article
Biomarkers of response to PD-1 pathway blockade.
Published in:
2022
By:
- Li, Hanxiao;
- van der Merwe, P Anton;
- Sivakumar, Shivan
Publication type:
journal article
Expression of Checkpoint Molecules in the Tumor Microenvironment of Intrahepatic Cholangiocarcinoma: Implications for Immune Checkpoint Blockade Therapy.
Published in:
Cells (2073-4409), 2023, v. 12, n. 6, p. 851, doi. 10.3390/cells12060851
By:
- Heij, Lara;
- Bednarsch, Jan;
- Tan, Xiuxiang;
- Rosin, Mika;
- Appinger, Simone;
- Reichel, Konrad;
- Pecina, Dana;
- Doukas, Michail;
- van Dam, Ronald M.;
- Garcia Vallejo, Juan;
- Ulmer, Florian;
- Lang, Sven;
- Luedde, Tom;
- Rocha, Flavio G.;
- Sivakumar, Shivan;
- Neumann, Ulf Peter
Publication type:
Article
Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis.
Published in:
2017
By:
- Sivakumar, Shivan;
- de Santiago, Ines;
- Chlon, Leon;
- Markowetz, Florian
Publication type:
journal article
A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease.
Published in:
Experimental Hematology & Oncology, 2023, v. 12, n. 1, p. 1, doi. 10.1186/s40164-023-00458-3
By:
- Mato Prado, Mireia;
- Puik, Jisce R.;
- Castellano, Leandro;
- López-Jiménez, Elena;
- Liu, Daniel S. K.;
- Meijer, Laura L.;
- Le Large, Tessa Y. S.;
- Rees, Eleanor;
- Funel, Niccola;
- Sivakumar, Shivan;
- Pereira, Stephen P.;
- Kazemier, Geert;
- Zonderhuis, Babs M.;
- Erdmann, Joris I.;
- Swijnenburg, Rutger-Jan;
- Frilling, Andrea;
- Jiao, Long R.;
- Stebbing, Justin;
- Giovannetti, Elisa;
- Krell, Jonathan
Publication type:
Article
Manipulating regulatory T cells: is it the key to unlocking effective immunotherapy for pancreatic ductal adenocarcinoma?
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1406250
By:
- Smith, Henry;
- Arbe-Barnes, Edward;
- Shah, Enas Abu;
- Sivakumar, Shivan
Publication type:
Article
Bile Microbiome Signatures Associated with Pancreatic Ductal Adenocarcinoma Compared to Benign Disease: A UK Pilot Study.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16888, doi. 10.3390/ijms242316888
By:
- Merali, Nabeel;
- Chouari, Tarak;
- Terroire, Julien;
- Jessel, Maria-Danae;
- Liu, Daniel S. K.;
- Smith, James-Halle;
- Wooldridge, Tyler;
- Dhillon, Tony;
- Jiménez, José I.;
- Krell, Jonathan;
- Roberts, Keith J.;
- Rockall, Timothy A.;
- Velliou, Eirini;
- Sivakumar, Shivan;
- Giovannetti, Elisa;
- Demirkan, Ayse;
- Annels, Nicola E.;
- Frampton, Adam E.
Publication type:
Article

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