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Mitochondrial energetics in skeletal muscle are associated with leg power and cardiorespiratory fitness in the Study of Muscle, Mobility, and Aging (SOMMA).
Published in:
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2023, v. 78, n. 8, p. 1367, doi. 10.1093/gerona/glac238
By:
- Mau, Theresa;
- Lui, Li-Yung;
- Distefano, Giovanna;
- Kramer, Philip A;
- Ramos, Sofhia V;
- Toledo, Frederico G S;
- Santanasto, Adam J;
- Shankland, Eric G;
- Marcinek, David J;
- Jurczak, Michael J;
- Sipula, Ian;
- Bello, Fiona M;
- Duchowny, Kate A;
- Molina, Anthony J A;
- Sparks, Lauren M;
- Goodpaster, Bret H;
- Hepple, Russell T;
- Kritchevsky, Stephen B;
- Newman, Anne B;
- Cawthon, Peggy M
Publication type:
Article
Elevated metabolic rate and skeletal muscle oxidative metabolism contribute to the reduced susceptibility of NF‐κB p50 null mice to obesity.
Published in:
Physiological Reports, 2018, v. 6, n. 18, p. 1, doi. 10.14814/phy2.13836
By:
- Bhatt, Bankim A.;
- Dedousis, Nikolaos;
- Sipula, Ian J.;
- O'Doherty, Robert M.
Publication type:
Article
Similar degrees of obesity induced by diet or aging cause strikingly different immunologic and metabolic outcomes.
Published in:
Physiological Reports, 2016, v. 4, n. 6, p. n/a, doi. 10.14814/phy2.12708
By:
- Krishna, Kanthi B.;
- Stefanovic‐Racic, Maja;
- Dedousis, Nikolaos;
- Sipula, Ian;
- O'Doherty, Robert M.
Publication type:
Article
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33308-7
By:
- Mushala, Bellina A. S.;
- Xie, Bingxian;
- Sipula, Ian J.;
- Stoner, Michael W.;
- Thapa, Dharendra;
- Manning, Janet R.;
- Bugga, Paramesha;
- Vandevender, Amber M.;
- Jurczak, Michael J.;
- Scott, Iain
Publication type:
Article
Mice Lacking NKT Cells but with a Complete Complement of CD8<sup>+</sup> T-Cells Are Not Protected against the Metabolic Abnormalities of Diet-Induced Obesity.
Published in:
PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0019831
By:
- Mantell, Benjamin S.;
- Stefanovic-Racic, Maja;
- Xiao Yang;
- Dedousis, Nikolas;
- Sipula, Ian J.;
- O'Doherty, Robert M.
Publication type:
Article
Characterizing the Therapeutic Potential of the Adropin‐GPR19 Signaling Pathway in MAFLD.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.L7527
By:
- Mushala, Bellina;
- Xie, Bingxian;
- Sipula, Ian;
- Jurczak, Michael;
- Scott, Iain
Publication type:
Article
Overexpression of Carnitine Palmitoyltransferase I Improves Obesity-Induced Hepatic Steatosis.
Published in:
Diabetes, 2007, v. 56, p. A40
By:
- Stefanovic-Racic, Maja;
- Mantell, Benjamin S.;
- Sipula, Ian J.;
- O'doherty, Robert M.
Publication type:
Article
Petite Integration Factor 1 (PIF1) helicase deficiency increases weight gain in Western diet-fed female mice without increased inflammatory markers or decreased glucose clearance.
Published in:
PLoS ONE, 2019, v. 14, n. 5, p. 1, doi. 10.1371/journal.pone.0203101
By:
- Belmonte, Frances R.;
- Dedousis, Nikolaos;
- Sipula, Ian;
- Desai, Nikita A.;
- Singhi, Aatur D.;
- Chu, Yanxia;
- Zhang, Yingze;
- Bannwarth, Sylvie;
- Paquis-Flucklinger, Véronique;
- Harrington, Lea;
- Shiva, Sruti;
- Jurczak, Michael J.;
- O’Doherty, Robert M.;
- Kaufman, Brett A.
Publication type:
Article
Inhibitory protein–protein interactions of the SIRT1 deacetylase are choreographed by post‐translational modification.
Published in:
Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 4, p. 1, doi. 10.1002/pro.4938
By:
- Krzysiak, Troy C.;
- Choi, You‐Jin;
- Kim, Yong Joon;
- Yang, Yunhan;
- DeHaven, Christopher;
- Thompson, Lariah;
- Ponticelli, Ryan;
- Mermigos, Mara M.;
- Thomas, Laurel;
- Marquez, Andrea;
- Sipula, Ian;
- Kemper, Jongsook Kim;
- Jurczak, Michael;
- Thomas, Gary;
- Gronenborn, Angela M.
Publication type:
Article
Role of Cardiorespiratory Fitness and Mitochondrial Oxidative Capacity in Reduced Walk Speed of Older Adults With Diabetes.
Published in:
Diabetes, 2024, v. 73, n. 7, p. 1048, doi. 10.2337/db23-0827
By:
- Ramos, Sofhia V.;
- Distefano, Giovanna;
- Lui, Li-Yung;
- Cawthon, Peggy M.;
- Kramer, Philip;
- Sipula, Ian J.;
- Bello, Fiona M.;
- Mau, Theresa;
- Jurczak, Michael J.;
- Molina, Anthony J.;
- Kershaw, Erin E.;
- Marcinek, David J.;
- Shankland, Eric;
- Toledo, Frederico G.S.;
- Newman, Anne B.;
- Hepple, Russell T.;
- Kritchevsky, Stephen B.;
- Goodpaster, Bret H.;
- Cummings, Steven R.;
- Coen, Paul M.
Publication type:
Article
371-OR: Reduced Hepatic Expression of the Mitochondrial Quality Control Factor PARKIN Hastens the Progression of NAFLD in Mice and Is Associated with NASH in Patients.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-371-OR
By:
- UNDAMATLA, RAMYA;
- EDMUNDS, LIA R.;
- XIE, BINGXIAN;
- MILLS, AMANDA;
- SIPULA, IAN J.;
- MONGA, SATDARSHAN P.;
- JURCZAK, MICHAEL J.
Publication type:
Article
Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.
Published in:
Diabetes, 2019, v. 68, n. 6, p. 1221, doi. 10.2337/db18-1198
By:
- Harmon, Daniel B.;
- Mandler, W. Kyle;
- Sipula, Ian J.;
- Dedousis, Nikolaos;
- Lewis, Sara E.;
- Eckels, Jeremy T.;
- Jianhai Du;
- Yekai Wang;
- Huckestein, Brydie R.;
- Pagano, Patrick J.;
- Cifuentes-Pagano, Eugenia;
- Homanics, Gregg E.;
- Van’t Erve, Thomas J.;
- Stefanovic-Racic, Maja;
- Jurczak, Michael J.;
- O’Doherty, Robert M.;
- Kelley, Eric E.
Publication type:
Article
Hepatocyte-Specific Ablation or Whole-Body Inhibition of Xanthine Oxidoreductase in Mice Corrects Obesity-Induced Systemic Hyperuricemia Without Improving Metabolic Abnormalities.
Published in:
2019
By:
- Harmon, Daniel B;
- Mandler, W Kyle;
- Sipula, Ian J;
- Dedousis, Nikolaos;
- Lewis, Sara E;
- Eckels, Jeremy T;
- Du, Jianhai;
- Wang, Yekai;
- Huckestein, Brydie R;
- Pagano, Patrick J;
- Ciefuentes-Pagano, Eugenia;
- Homanics, Gregg E;
- Van't Erve, Thomas J;
- Stefanovic-Racic, Maja;
- Jurczak, Michael J;
- O'Doherty, Robert M;
- Kelley, Eric E;
- Cifuentes-Pagano, Eugenia
Publication type:
journal article
Dendritic Cells Promote Macrophage Infiltration and Comprise a Substantial Proportion of Obesity-Associated Increases in CD11c<sup>+</sup> Cells in Adipose Tissue and Liver.
Published in:
Diabetes, 2012, v. 61, n. 9, p. 2330, doi. 10.2337/db11-1523
By:
- Stefanovic-Racic, Maja;
- Yang, Xiao;
- Turner, Michael S.;
- Mantell, Benjamin S.;
- Stolz, Donna B.;
- Sumpter, Tina L.;
- Sipula, Ian J.;
- Dedousis, Nikolaos;
- Scott, Donald K.;
- Morel, Penelope A.;
- Thomson, Angus W.;
- O'Doherty, Robert M.
Publication type:
Article
Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver.
Published in:
2012
By:
- Stefanovic-Racic M;
- Yang X;
- Turner MS;
- Mantell BS;
- Stolz DB;
- Sumpter TL;
- Sipula IJ;
- Dedousis N;
- Scott DK;
- Morel PA;
- Thomson AW;
- O'Doherty RM;
- Stefanovic-Racic, Maja;
- Yang, Xiao;
- Turner, Michael S;
- Mantell, Benjamin S;
- Stolz, Donna B;
- Sumpter, Tina L;
- Sipula, Ian J;
- Dedousis, Nikolaos
Publication type:
journal article
Depletion of Liver Kupffer Cells Prevents the Development of Diet-Induced Hepatic Steatosis and Insulin Resistance.
Published in:
Diabetes, 2010, v. 59, n. 2, p. 347, doi. 10.2337/db09-0016
By:
- Wan Huang;
- Metlakunta, Anantha;
- Dedousis, Nikolaos;
- Zhang, Pili;
- Sipula, Ian;
- Dube, John J.;
- Scott, Donald K.;
- O'Doherty, Robert M.
Publication type:
Article

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