Found: 116
Select item for more details and to access through your institution.
Direct GPCR-EGFR interaction enables synergistic membrane-to-nucleus information transfer.
- Published in:
- Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05281-5
- By:
- Publication type:
- Article
Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 5, p. 659, doi. 10.3390/ph17050659
- By:
- Publication type:
- Article
Design and synthesis of bioreductive prodrugs of class I histone deacetylase inhibitors and their biological evaluation in virally transfected acute myeloid leukemia cells.
- Published in:
- Archiv der Pharmazie, 2024, v. 357, n. 2, p. 1, doi. 10.1002/ardp.202300536
- By:
- Publication type:
- Article
Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 2, p. 1358, doi. 10.3390/ijms25021358
- By:
- Publication type:
- Article
Histone Acetyltransferase and Deacetylase Inhibitors—New Aspects and Developments.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16985, doi. 10.3390/ijms242316985
- By:
- Publication type:
- Article
NOXA Accentuates Apoptosis Induction by a Novel Histone Deacetylase Inhibitor.
- Published in:
- Cancers, 2023, v. 15, n. 14, p. 3650, doi. 10.3390/cancers15143650
- By:
- Publication type:
- Article
Application of Ligand- and Structure-Based Prediction Models for the Design of Alkylhydrazide-Based HDAC3 Inhibitors as Novel Anti-Cancer Compounds.
- Published in:
- Pharmaceuticals (14248247), 2023, v. 16, n. 7, p. 968, doi. 10.3390/ph16070968
- By:
- Publication type:
- Article
IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression.
- Published in:
- Molecular Cancer, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12943-023-01792-0
- By:
- Publication type:
- Article
Editorial for Special Issue—"Early-Stage Drug Discovery: Advances and Challenges".
- Published in:
- 2023
- By:
- Publication type:
- Editorial
Translational molecular imaging and drug development in Parkinson's disease.
- Published in:
- Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00600-z
- By:
- Publication type:
- Article
Front Cover: Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages (ChemMedChem 3/2023).
- Published in:
- ChemMedChem, 2023, v. 18, n. 3, p. 1, doi. 10.1002/cmdc.202300028
- By:
- Publication type:
- Article
Chemically Diverse S. mansoni HDAC8 Inhibitors Reduce Viability in Worm Larval and Adult Stages.
- Published in:
- ChemMedChem, 2023, v. 18, n. 3, p. 1, doi. 10.1002/cmdc.202200510
- By:
- Publication type:
- Article
N 4 -(2-Amino-4-fluorophenyl)- N 1 -(3-{2-[2-(3-{[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino}propoxy)ethoxy]ethoxy}propyl)terephthalamide.
- Published in:
- Molbank, 2022, v. 2022, n. 4, p. M1501, doi. 10.3390/M1501
- By:
- Publication type:
- Article
Development and Validation of [ 3 H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs.
- Published in:
- Pharmaceuticals (14248247), 2022, v. 15, n. 8, p. 960, doi. 10.3390/ph15080960
- By:
- Publication type:
- Article
First Fluorescent Acetylspermidine Deacetylation Assay for HDAC10 Identifies Selective Inhibitors with Cellular Target Engagement**.
- Published in:
- ChemBioChem, 2022, v. 23, n. 14, p. 1, doi. 10.1002/cbic.202200180
- By:
- Publication type:
- Article
Design, Synthesis and Biological Characterization of Histone Deacetylase 8 (HDAC8) Proteolysis Targeting Chimeras (PROTACs) with Anti-Neuroblastoma Activity.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 14, p. 7535, doi. 10.3390/ijms23147535
- By:
- Publication type:
- Article
Docking, Binding Free Energy Calculations and In Vitro Characterization of Pyrazine Linked 2-Aminobenzamides as Novel Class I Histone Deacetylase (HDAC) Inhibitors.
- Published in:
- Molecules, 2022, v. 27, n. 8, p. N.PAG, doi. 10.3390/molecules27082526
- By:
- Publication type:
- Article
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 369, doi. 10.3390/ijms23010369
- By:
- Publication type:
- Article
Histone Deacetylase (HDAC) Inhibitors for the Treatment of Schistosomiasis.
- Published in:
- Pharmaceuticals (14248247), 2022, v. 15, n. 1, p. 80, doi. 10.3390/ph15010080
- By:
- Publication type:
- Article
Histone deacetylase 8 interacts with the GTPase SmRho1 in Schistosoma mansoni.
- Published in:
- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 11, p. 1, doi. 10.1371/journal.pntd.0009503
- By:
- Publication type:
- Article
An Analysis Based on Molecular Docking and Molecular Dynamics Simulation Study of Bromelain as Anti-SARS-CoV-2 Variants.
- Published in:
- Frontiers in Pharmacology, 2021, v. 12, p. 1, doi. 10.3389/fphar.2021.717757
- By:
- Publication type:
- Article
Design, synthesis, and molecular docking of novel 3,5‐disubstituted‐1,3,4‐oxadiazole derivatives as iNOS inhibitors.
- Published in:
- Archiv der Pharmazie, 2021, v. 354, n. 8, p. 1, doi. 10.1002/ardp.202000469
- By:
- Publication type:
- Article
Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 11, p. 5910, doi. 10.3390/ijms22115910
- By:
- Publication type:
- Article
Exploring aromatic cage flexibility of the histone methyllysine reader protein Spindlin1 and its impact on binding mode prediction: an in silico study.
- Published in:
- Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 6, p. 695, doi. 10.1007/s10822-021-00391-9
- By:
- Publication type:
- Article
Strategies To Design Selective Histone Deacetylase Inhibitors.
- Published in:
- ChemMedChem, 2021, v. 16, n. 9, p. 1336, doi. 10.1002/cmdc.202000934
- By:
- Publication type:
- Article
Design, synthesis, and biological evaluation of new urolithin amides as multitarget agents against Alzheimer's disease.
- Published in:
- Archiv der Pharmazie, 2021, v. 354, n. 5, p. 1, doi. 10.1002/ardp.202000467
- By:
- Publication type:
- Article
Binding Free Energy (BFE) Calculations and Quantitative Structure–Activity Relationship (QSAR) Analysis of Schistosoma mansoni Histone Deacetylase 8 (sm HDAC8) Inhibitors.
- Published in:
- Molecules, 2021, v. 26, n. 9, p. 2584, doi. 10.3390/molecules26092584
- By:
- Publication type:
- Article
Effects of Environmental Conditions on Nephron Number: Modeling Maternal Disease and Epigenetic Regulation in Renal Development.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 4157, doi. 10.3390/ijms22084157
- By:
- Publication type:
- Article
Efficacy of Souroubea-Platanus Dietary Supplement Containing Triterpenes in Beagle Dogs Using a Thunderstorm Noise-Induced Model of Fear and Anxiety.
- Published in:
- Molecules, 2021, v. 26, n. 7, p. 2049, doi. 10.3390/molecules26072049
- By:
- Publication type:
- Article
PepFun: Open Source Protocols for Peptide-Related Computational Analysis.
- Published in:
- Molecules, 2021, v. 26, n. 6, p. 1664, doi. 10.3390/molecules26061664
- By:
- Publication type:
- Article
The potential for histone deacetylase (HDAC) inhibitors as cestocidal drugs.
- Published in:
- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 3, p. 1, doi. 10.1371/journal.pntd.0009226
- By:
- Publication type:
- Article
Editorial to Special Issue—"Structure-Activity Relationships (SAR) of Natural Products".
- Published in:
- 2021
- By:
- Publication type:
- Editorial
Alkaloids with Anti-Onchocercal Activity from Voacanga africana Stapf (Apocynaceae): Identification and Molecular Modeling.
- Published in:
- Molecules, 2021, v. 26, n. 1, p. 70, doi. 10.3390/molecules26010070
- By:
- Publication type:
- Article
How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition—The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine.
- Published in:
- Molecules, 2020, v. 25, n. 24, p. 5962, doi. 10.3390/molecules25245962
- By:
- Publication type:
- Article
HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)**.
- Published in:
- ChemBioChem, 2020, v. 21, n. 23, p. 3371, doi. 10.1002/cbic.202000351
- By:
- Publication type:
- Article
Pharmacoinformatic Investigation of Medicinal Plants from East Africa.
- Published in:
- Molecular Informatics, 2020, v. 39, n. 11, p. 1, doi. 10.1002/minf.202000163
- By:
- Publication type:
- Article
Synthesis, Characterization, Molecular Docking, and Biological Activities of Some Natural and Synthetic Urolithin Analogs.
- Published in:
- Chemistry & Biodiversity, 2020, v. 17, n. 8, p. 1, doi. 10.1002/cbdv.202000197
- By:
- Publication type:
- Article
Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1.
- Published in:
- Molecules, 2020, v. 25, n. 15, p. 3496, doi. 10.3390/molecules25153496
- By:
- Publication type:
- Article
Natural Products as Modulators of Sirtuins.
- Published in:
- Molecules, 2020, v. 25, n. 14, p. 3287, doi. 10.3390/molecules25143287
- By:
- Publication type:
- Article
Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.
- Published in:
- PLoS Neglected Tropical Diseases, 2020, v. 14, n. 7, p. 1, doi. 10.1371/journal.pntd.0008332
- By:
- Publication type:
- Article
Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening.
- Published in:
- Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00905
- By:
- Publication type:
- Article
The potential of anti-malarial compounds derived from African medicinal plants: a review of pharmacological evaluations from 2013 to 2019.
- Published in:
- Malaria Journal, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12936-020-03231-7
- By:
- Publication type:
- Article
Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD<sup>+</sup> Dependent Lysine Deacetylases.
- Published in:
- Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2020.00657
- By:
- Publication type:
- Article
Structure-Dependent Activity of Plant-Derived Sweeteners.
- Published in:
- Molecules, 2020, v. 25, n. 8, p. 1946, doi. 10.3390/molecules25081946
- By:
- Publication type:
- Article
Front Cover: Structure‐Based Design, Synthesis, and Biological Evaluation of Triazole‐Based smHDAC8 Inhibitors (ChemMedChem 7/2020).
- Published in:
- ChemMedChem, 2020, v. 15, n. 7, p. 559, doi. 10.1002/cmdc.201000139
- By:
- Publication type:
- Article
Structure‐Based Design, Synthesis, and Biological Evaluation of Triazole‐Based smHDAC8 Inhibitors.
- Published in:
- ChemMedChem, 2020, v. 15, n. 7, p. 571, doi. 10.1002/cmdc.201900583
- By:
- Publication type:
- Article
Enhancing the Membranolytic Activity of Chenopodiumquinoa Saponins by Fast Microwave Hydrolysis.
- Published in:
- Molecules, 2020, v. 25, n. 7, p. 1731, doi. 10.3390/molecules25071731
- By:
- Publication type:
- Article
Protective Effect of Genistein against Compound 48/80 Induced Anaphylactoid Shock via Inhibiting MAS Related G Protein-Coupled Receptor X2 (MRGPRX2).
- Published in:
- Molecules, 2020, v. 25, n. 5, p. 1028, doi. 10.3390/molecules25051028
- By:
- Publication type:
- Article
Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-<sup>11</sup>C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and Tightrope Walk between GluN2B- and Sigma1 Receptor-Targeted PET Imaging.
- Published in:
- Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.118.22105
- By:
- Publication type:
- Article
Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-<sup>11</sup>C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and <sub>σ1</sub>-Receptor--Targeted PET Imaging.
- Published in:
- Journal of Nuclear Medicine, 2019, v. 60, n. 8, p. 1167, doi. 10.2967/jnumed.118.221051
- By:
- Publication type:
- Article