Works by Singleton, Andrew

Results: 293
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    LRRK2-associated parkinsonism with and without in vivo evidence of alpha-synuclein aggregates: longitudinal clinical and biomarker characterization.

    Published in:
    Brain Communications, 2025, v. 7, n. 2, p. 1, doi. 10.1093/braincomms/fcaf103
    By:
    • Chahine, Lana M;
    • Lafontant, David-Erick;
    • Choi, Seung Ho;
    • Iwaki, Hirotaka;
    • Blauwendraat, Cornelis;
    • Singleton, Andrew B;
    • Brumm, Michael C;
    • Alcalay, Roy N;
    • Merchant, Kalpana;
    • Nudelman, Kelly Nicole Holohan;
    • Dagher, Alain;
    • Vo, Andrew;
    • Tao, Qin;
    • Venuto, Charles S;
    • Kieburtz, Karl;
    • Poston, Kathleen L;
    • Bressman, Susan;
    • Gonzalez-Latapi, Paulina;
    • Avants, Brian;
    • Coffey, Christopher
    Publication type:
    Article
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    Investigation of the genetic aetiology of Lewy body diseases with and without dementia.

    Published in:
    Brain Communications, 2024, v. 6, n. 4, p. 1, doi. 10.1093/braincomms/fcae190
    By:
    • Wu, Lesley Yue;
    • Real, Raquel;
    • Martinez-Carrasco, Alejandro;
    • Chia, Ruth;
    • Lawton, Michael A;
    • Shoai, Maryam;
    • Bresner, Catherine;
    • Blauwendraat, Cornelis;
    • Singleton, Andrew B;
    • Ryten, Mina;
    • Consortium, International Lewy Body Dementia Genomics;
    • Scholz, Sonja W;
    • Traynor, Bryan J;
    • Williams, Nigel M;
    • Hu, Michele T M;
    • Ben-Shlomo, Yoav;
    • Grosset, Donald G;
    • Hardy, John;
    • Morris, Huw R
    Publication type:
    Article
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    Analysis of Y chromosome haplogroups in Parkinson's disease.

    Published in:
    Brain Communications, 2022, v. 4, n. 6, p. 1, doi. 10.1093/braincomms/fcac277
    By:
    • Grenn, Francis P.;
    • Makarious, Mary B.;
    • Bandres-Ciga, Sara;
    • Hirotaka Iwaki;
    • Singleton, Andrew B.;
    • Nalls, Mike A.;
    • Blauwendraat, Cornelis
    Publication type:
    Article
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    Moving towards the detection of frailty with biomarkers: A population health study.

    Published in:
    Aging Cell, 2024, v. 23, n. 2, p. 1, doi. 10.1111/acel.14030
    By:
    • Sargent, Lana;
    • Nalls, Mike;
    • Singleton, Andrew;
    • Palta, Priya;
    • Kucharska‐Newton, Anna;
    • Pankow, Jim;
    • Young, Hunter;
    • Tang, Weihong;
    • Lutsey, Pamela;
    • Olex, Amy;
    • Wendte, Jered M.;
    • Li, Danni;
    • Alonso, Alvaro;
    • Griswold, Michael;
    • Windham, B. Gwen;
    • Baninelli, Stefania;
    • Ferrucci, Luigi
    Publication type:
    Article
    6

    Towards a gene expression biomarker set for human biological age.

    Published in:
    Aging Cell, 2013, v. 12, n. 2, p. 324, doi. 10.1111/acel.12044
    By:
    • Holly, Alice C.;
    • Melzer, David;
    • Pilling, Luke C.;
    • Henley, William;
    • Hernandez, Dena G.;
    • Singleton, Andrew B.;
    • Bandinelli, Stefania;
    • Guralnik, Jack M.;
    • Ferrucci, Luigi;
    • Harries, Lorna W.
    Publication type:
    Article
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    A 6.4 Mb Duplication of the a-Synuclein Locus Causing Frontotemporal Dementia and Parkinsonism Phenotype-Genotype Correlations.

    Published in:
    JAMA Neurology, 2014, v. 71, n. 9, p. 1162, doi. 10.1001/jamaneurol.2014.994
    By:
    • Kara, Eleanna;
    • Kiely, Aoife P.;
    • Proukakis, Christos;
    • Giffin, Nicola;
    • Love, Seth;
    • Hehir, Jason;
    • Rantell, Khadija;
    • Pandraud, Amelie;
    • Hernandez, Dena G.;
    • Nacheva, Elizabeth;
    • Pittman, Alan M.;
    • Nalls, Mike A.;
    • Singleton, Andrew B.;
    • Revesz, Tamas;
    • Bhatia, Kailash P.;
    • Quinn, Niall;
    • Hardy, John;
    • Holton, Janice L.;
    • Houlden, Henry
    Publication type:
    Article
    13

    Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau<sub>181</sub>, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease.

    Published in:
    JAMA Neurology, 2013, v. 70, n. 10, p. 1277, doi. 10.1001/jamaneurol.2013.3861
    By:
    • Ju-Hee Kang;
    • Irwin, David J.;
    • Chen-Plotkin, Alice S.;
    • Siderowf, Andrew;
    • Caspell, Chelsea;
    • Coffey, Christopher S.;
    • Waligórska, Teresa;
    • Taylor, Peggy;
    • Pan, Sarah;
    • Frasier, Mark;
    • Marek, Kenneth;
    • Kieburtz, Karl;
    • Jennings, Danna;
    • Simuni, Tanya;
    • Tanner, Caroline M.;
    • Singleton, Andrew;
    • Toga, Arthur W.;
    • Chowdhury, Sohini;
    • Mollenhauer, Brit;
    • Trojanowski, John Q.
    Publication type:
    Article
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    Towards a Global View of Parkinson's Disease Genetics.

    Published in:
    Annals of Neurology, 2024, v. 95, n. 5, p. 831, doi. 10.1002/ana.26905
    By:
    • Khani, Marzieh;
    • Cerquera‐Cleves, Catalina;
    • Kekenadze, Mariam;
    • Wild Crea, Peter;
    • Singleton, Andrew B.;
    • Bandres‐Ciga, Sara
    Publication type:
    Article
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    A comprehensive analysis of SNCA-related genetic risk in sporadic parkinson disease.

    Published in:
    2018
    By:
    • Pihlstrøm, Lasse;
    • Blauwendraat, Cornelis;
    • Cappelletti, Chiara;
    • Berge‐seidl, Victoria;
    • Langmyhr, Margrete;
    • Henriksen, Sandra Pilar;
    • Van De Berg, Wilma D. J.;
    • Gibbs, J. Raphael;
    • Cookson, Mark R.;
    • The International Parkinson Disease Genomics Consortium;
    • The North American Brain Expression Consortium;
    • Singleton, Andrew B.;
    • Nalls, Mike A.;
    • Toft, Mathias;
    • Berge-Seidl, Victoria;
    • International Parkinson Disease Genomics Consortium;
    • North American Brain Expression Consortium
    Publication type:
    journal article
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    Is the MC1R variant p.R160W associated with Parkinson's?

    Published in:
    2016
    By:
    • Lubbe, Steven J.;
    • Escott‐Price, Valentina;
    • Brice, Alexis;
    • Gasser, Thomas;
    • Hardy, John;
    • Heutink, Peter;
    • Sharma, Manu;
    • Wood, Nicholas W.;
    • Nalls, Mike;
    • Singleton, Andrew B.;
    • Williams, Nigel M.;
    • Morris, Huw R.;
    • Escott-Price, Valentina;
    • International Parkinson's Disease Genomics Consortium
    Publication type:
    Letter
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    P3-213: Genetic screening in a large cohort of early-onset Alzheimer's disease patients from Spain: Novel mutations in the amyloid precursor protein and presenilines

    Published in:
    2008
    By:
    • Clarimón, Jordi;
    • Guerreiro, Rita;
    • Lleó, Alberto;
    • Guardia, Cristina;
    • Blesa, Rafael;
    • Gómez-Isla, Teresa;
    • Boada, Merce;
    • Bullido, Jesus;
    • Ferrer, Isidre;
    • Martínez-Lage, Pablo;
    • Masdeu, Jose;
    • Molina, Laura;
    • Molinuevo, José Luís;
    • Pastor, Pau;
    • Pérez-Tur, Jordi;
    • Rey, Jesus;
    • Sánchez-Valle, Raquel;
    • Tàrraga, Lluís;
    • Valdivieso, Fernando;
    • Singleton, Andrew
    Publication type:
    Abstract
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    Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

    Published in:
    2017
    By:
    • Noyce, Alastair J.;
    • Kia, Demis A.;
    • Hemani, Gibran;
    • Nicolas, Aude;
    • Price, T. Ryan;
    • De Pablo-Fernandez, Eduardo;
    • Haycock, Philip C.;
    • Lewis, Patrick A.;
    • Foltynie, Thomas;
    • Davey Smith, George;
    • null, null;
    • Schrag, Anette;
    • Lees, Andrew J.;
    • Hardy, John;
    • Singleton, Andrew;
    • Nalls, Mike A.;
    • Pearce, Neil;
    • Lawlor, Debbie A.;
    • Wood, Nicholas W.;
    • International Parkinson Disease Genomics Consortium
    Publication type:
    journal article
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    Analysis of repeated leukocyte DNA methylation assessments reveals persistent epigenetic alterations after an incident myocardial infarction.

    Published in:
    Clinical Epigenetics, 2018, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13148-018-0588-7
    By:
    • Ward-Caviness, Cavin K.;
    • Agha, Golareh;
    • Chen, Brian H.;
    • Pfeiffer, Liliane;
    • Wilson, Rory;
    • Wolf, Petra;
    • Gieger, Christian;
    • Schwartz, Joel;
    • Vokonas, Pantel S.;
    • Hou, Lifang;
    • Just, Allan C.;
    • Bandinelli, Stefania;
    • Hernandez, Dena G.;
    • Singleton, Andrew B.;
    • Prokisch, Holger;
    • Meitinger, Thomas;
    • Kastenmüller, Gabi;
    • Ferrucci, Luigi;
    • Baccarelli, Andrea A.;
    • Waldenberger, Melanie
    Publication type:
    Article
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    Book Reviews.

    Published in:
    2000
    By:
    • Mitchell, Richard;
    • Le Couteur, Amanda;
    • Singleton, Andrew;
    • Taket, Ann;
    • Mcgowan, Fiona;
    • Heslop, Pauline;
    • Harding, Geoff
    Publication type:
    Book Review
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    Characterization of PLA2G6 as a locus for dystonia-parkinsonism.

    Published in:
    Annals of Neurology, 2009, v. 65, n. 1, p. 19, doi. 10.1002/ana.21415
    By:
    • Paisan-Ruiz, Coro;
    • Bhatia, Kailash P.;
    • Li, Abi;
    • Hernandez, Dena;
    • Davis, Mary;
    • Wood, Nick W.;
    • Hardy, John;
    • Houlden, Henry;
    • Singleton, Andrew;
    • Schneider, Susanne A.
    Publication type:
    Article
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    Clinical heterogeneity of α‐synuclein gene duplication in Parkinson's disease.

    Published in:
    Annals of Neurology, 2006, v. 59, n. 2, p. 298
    By:
    • Kenya Nishioka;
    • Shin Hayashi;
    • Matthew J. Farrer;
    • Andrew B. Singleton;
    • Hiroyo Yoshino;
    • Hisamasa Imai;
    • Toshiaki Kitami;
    • Kenichi Sato;
    • Ryu Kuroda;
    • Hiroyuki Tomiyama;
    • Koichi Mizoguchi;
    • Miho Murata;
    • Tatsushi Toda;
    • Issei Imoto;
    • Johji Inazawa;
    • Yoshikuni Mizuno;
    • Nobutaka Hattori
    Publication type:
    Article
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    Clinical and positron emission tomography of Parkinson's disease caused by LRRK2.

    Published in:
    Annals of Neurology, 2005, v. 57, n. 3, p. 453
    By:
    • Dena G. Hernandez;
    • Coro Paisán‐Ruíz;
    • Aideen McInerney‐Leo;
    • Shushant Jain;
    • Andreas Meyer‐Lindenberg;
    • E. Whitney Evans;
    • Karen F. Berman;
    • Janel Johnson;
    • Georg Auburger;
    • Alejandro A. Schäffer;
    • Grisel J. Lopez;
    • Robert L. Nussbaum;
    • Andrew B. Singleton
    Publication type:
    Article
    45

    Reply.

    Published in:
    Annals of Neurology, 2004, v. 55, n. 1, p. 145
    By:
    • E. Whitney Evans;
    • Stephen Hague;
    • Andrew Singleton
    Publication type:
    Article
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    Early-onset Parkinson's disease caused by a compound heterozygous DJ-1 mutation.

    Published in:
    Annals of Neurology, 2003, v. 54, n. 2, p. 271
    By:
    • Stephen Hague;
    • Ekaterina Rogaeva;
    • Dena Hernandez;
    • Cindy Gulick;
    • Amanda Singleton;
    • Melissa Hanson;
    • Janel Johnson;
    • Roberto Weiser;
    • Marisol Gallardo;
    • Bernard Ravina;
    • Katrina Gwinn-Hardy;
    • Anthony Crawley;
    • Peter H. St. George-Hyslop;
    • Anthony E. Lang;
    • Peter Heutink;
    • Vincenzo Bonifati;
    • John Hardy;
    • Andrew Singleton
    Publication type:
    Article
    47

    Case-Control study of the extended tau gene haplotype in Parkinson's disease.

    Published in:
    2001
    By:
    • Maraganore, Demetrius M.;
    • Hernandez, Dena G.;
    • Singleton, Andrew B.;
    • Farrer, Matthew J.;
    • McDonnell, Shannon K.;
    • Hutton, Michael L.;
    • Hardy, John A.;
    • Rocca, Walter A.;
    • Maraganore, D M;
    • Hernandez, D G;
    • Singleton, A B;
    • Farrer, M J;
    • McDonnell, S K;
    • Hutton, M L;
    • Hardy, J A;
    • Rocca, W A
    Publication type:
    journal article
    48

    Lewy bodies and parkinsonism in families with parkin mutations.

    Published in:
    2001
    By:
    • Farrer, Matt;
    • Chan, Piu;
    • Chen, Rong;
    • Tan, Louis;
    • Lincoln, Sarah;
    • Hernandez, Dena;
    • Forno, Lysia;
    • Gwinn-Hardy, Katrina;
    • Petrucelli, Leonard;
    • Hussey, Jennifer;
    • Singleton, Andrew;
    • Tanner, Caroline;
    • Hardy, John;
    • Langston, J. William;
    • Farrer, M;
    • Chan, P;
    • Chen, R;
    • Tan, L;
    • Lincoln, S;
    • Hernandez, D
    Publication type:
    journal article
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