Works by Singh, Shailja

Results: 88

CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07968-2

By:

Kumari, Geeta;
Gupta, Pragya;
Goswami, Sangam G.;
Jain, Ravi;
Anand, Sakshi;
Biswas, Shreeja;
Garg, Swati;
Thakur, Priya;
Saravanakumar, Vinodh;
Arvinden, V. R.;
Goswami, Bidhan;
Bhowmick, Ipsita Pal;
Mohandas, Narla;
Burrows, Jeremy;
Ramalingam, Sivaprakash;
Singh, Shailja

Publication type:

Article

Removal of Dyes from Waste Water Using Low‐Cost Adsorbents.

Published in:

Macromolecular Symposia, 2024, v. 413, n. 5, p. 1, doi. 10.1002/masy.202400156

By:

Singh, Shailja;
Kumar, Navneet

Publication type:

Article

Comparative investigation on interaction between potent antimalarials and human serum albumin using multispectroscopic and computational approaches.

Published in:

Luminescence: Journal of Biological & Chemical Luminescence, 2023, v. 38, n. 12, p. 2018, doi. 10.1002/bio.4590

By:

Azeem, Kashish;
Ahmed, Mofieed;
Uddin, Amad;
Singh, Shailja;
Patel, Rajan;
Abid, Mohammad

Publication type:

Article

Cytoprotective autophagy as a pro-survival strategy in ART-resistant malaria parasites.

Published in:

Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01401-5

By:

Kannan, Deepika;
Joshi, Nishant;
Gupta, Sonal;
Pati, Soumya;
Bhattacharjee, Souvik;
Langsley, Gordon;
Singh, Shailja

Publication type:

Article

Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity.

Published in:

Frontiers in Bioengineering & Biotechnology, 2025, p. 1, doi. 10.3389/fbioe.2025.1528570

By:

Babu, R.;
Veeramani, Manokaran;
Aadinath, Wallepure;
Muthuvijayan, Vignesh;
Singh, Shailja;
Srivastava, Smita

Publication type:

Article

In vitro and in vivo antiplasmodial evaluation of sugar-modified nucleoside analogues.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39541-4

By:

Bege, Miklós;
Singh, Vigyasa;
Sharma, Neha;
Debreczeni, Nóra;
Bereczki, Ilona;
Poonam;
Herczegh, Pál;
Rathi, Brijesh;
Singh, Shailja;
Borbás, Anikó

Publication type:

Article

Identification and Characterization of a Novel Palmitoyl Acyltransferase as a Druggable Rheostat of Dynamic Palmitoylome in <italic>L. donovani</italic>.

Published in:

Frontiers in Cellular & Infection Microbiology, 2018, v. 8, p. N.PAG, doi. 10.3389/fcimb.2018.00186

By:

Ayana, R.;
Yadav, Preeti;
Kumari, Rajesh;
Ramu, Dandugudumula;
Garg, Swati;
Pati, Soumya;
Singh, Shailja

Publication type:

Article

Perforin-like protein PPLP2 permeabilizes the red blood cell membrane during egress of P lasmodium falciparum gametocytes.

Published in:

Cellular Microbiology, 2014, v. 16, n. 5, p. 709, doi. 10.1111/cmi.12288

By:

Wirth, Christine C.;
Glushakova, Svetlana;
Scheuermayer, Matthias;
Repnik, Urska;
Garg, Swati;
Schaack, Dominik;
Kachman, Marika M.;
Weißbach, Tim;
Zimmerberg, Joshua;
Dandekar, Thomas;
Griffiths, Gareth;
Chitnis, Chetan E.;
Singh, Shailja;
Fischer, Rainer;
Pradel, Gabriele

Publication type:

Article

Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion.

Published in:

Cellular Microbiology, 2014, v. 16, n. 1, p. 50, doi. 10.1111/cmi.12177

By:

Singh, Shailja;
More, Kunal R.;
Chitnis, Chetan E.

Publication type:

Article

A thrombospondin structural repeat containing rhoptry protein from Plasmodium falciparum mediates erythrocyte invasion.

Published in:

Cellular Microbiology, 2013, v. 15, n. 8, p. 1341, doi. 10.1111/cmi.12118

By:

Siddiqui, Faiza Amber;
Dhawan, Shikha;
Singh, Shailja;
Singh, Bijender;
Gupta, Pankaj;
Pandey, Alok;
Mohmmed, Asif;
Gaur, Deepak;
Chitnis, Chetan E.

Publication type:

Article

Ca<sup>2+</sup>-mediated exocytosis of subtilisin-like protease 1: a key step in egress of Plasmodium falciparum merozoites.

Published in:

Cellular Microbiology, 2013, v. 15, n. 6, p. 910, doi. 10.1111/cmi.12086

By:

Agarwal, Shalini;
Singh, Maneesh Kumar;
Garg, Swati;
Chitnis, Chetan E.;
Singh, Shailja

Publication type:

Article

Development of Mitochondria Targeting AIE‐Active Cyclometalated Iridium Complexes as Potent Antimalarial Agents.

Published in:

Advanced Healthcare Materials, 2023, v. 12, n. 9, p. 1, doi. 10.1002/adhm.202202411

By:

Kumari, Geeta;
Gupta, Ajay;
Sah, Raj Kumar;
Gautam, Aryan;
Saini, Monika;
Gupta, Aashima;
Kushawaha, Akhilesh K.;
Singh, Shailja;
Sasmal, Pijus K.

Publication type:

Article

Development of pathophysiologically relevant models of sickle cell disease and β-thalassemia for therapeutic studies.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46036-x

By:

Gupta, Pragya;
Goswami, Sangam Giri;
Kumari, Geeta;
Saravanakumar, Vinodh;
Bhargava, Nupur;
Rai, Akhila Balakrishna;
Singh, Praveen;
Bhoyar, Rahul C.;
Arvinden, V. R.;
Gunda, Padma;
Jain, Suman;
Narayana, Vanya Kadla;
Deolankar, Sayali C.;
Prasad, T. S. Keshava;
Natarajan, Vivek T.;
Scaria, Vinod;
Singh, Shailja;
Ramalingam, Sivaprakash

Publication type:

Article

Development of pathophysiologically relevant models of sickle cell disease and β-thalassemia for therapeutic studies.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46036-x

By:

Gupta, Pragya;
Goswami, Sangam Giri;
Kumari, Geeta;
Saravanakumar, Vinodh;
Bhargava, Nupur;
Rai, Akhila Balakrishna;
Singh, Praveen;
Bhoyar, Rahul C.;
Arvinden, V. R.;
Gunda, Padma;
Jain, Suman;
Narayana, Vanya Kadla;
Deolankar, Sayali C.;
Prasad, T. S. Keshava;
Natarajan, Vivek T.;
Scaria, Vinod;
Singh, Shailja;
Ramalingam, Sivaprakash

Publication type:

Article

Deconvolution of human Brain cell Type Transcriptomes Unraveled Microglia-specific Potential Biomarkers.

Published in:

Frontiers in Neurology, 2018, p. 1, doi. 10.3389/fneur.2018.00266

By:

Ayana, R.;
Singh, Shailja;
Pati, Soumya

Publication type:

Article

Exploring riverine solute behavior, dynamics, and export into the Arabian Sea from a semi-arid catchment, Western India.

Published in:

Environmental Earth Sciences, 2024, v. 83, n. 2, p. 1, doi. 10.1007/s12665-023-11348-6

By:

Singh, Shailja;
Das, Anirban;
Sudheer, A. K.;
Gaddam, Mahesh

Publication type:

Article

Plasmodium falciparum PhIL1-associated complex plays an essential role in merozoite reorientation and invasion of host erythrocytes.

Published in:

PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009750

By:

Saini, Ekta;
Sheokand, Pradeep Kumar;
Sharma, Vaibhav;
Agrawal, Prakhar;
Kaur, Inderjeet;
Singh, Shailja;
Mohmmed, Asif;
Malhotra, Pawan

Publication type:

Article

Design and synthesis of imidazolidinone derivatives as potent anti‐leishmanial agents by bioisosterism.

Published in:

Archiv der Pharmazie, 2019, v. 352, n. 4, p. N.PAG, doi. 10.1002/ardp.201800290

By:

Ramu, Dandugudumula;
Jain, Ravi;
Kumar, Ravi R.;
Sharma, Veena;
Garg, Swati;
Ayana, Rajagopal;
Luthra, Tania;
Yadav, Preeti;
Sen, Subhabrata;
Singh, Shailja

Publication type:

Article

Phosphatidic acid homeostasis regulated by a type-2 phosphatidic acid phosphatase represents a novel druggable target in malaria intervention.

Published in:

Cell Death Discovery, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41420-019-0187-1

By:

Kumar Sah, Raj;
Garg, Swati;
Dangi, Poonam;
Ponnusamy, Kalaiarasan;
Singh, Shailja

Publication type:

Article

Interaction of Plasmodium falciparum apicortin with α- and β-tubulin is critical for parasite growth and survival.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-83513-5

By:

Chakrabarti, Malabika;
Joshi, Nishant;
Kumari, Geeta;
Singh, Preeti;
Shoaib, Rumaisha;
Munjal, Akshay;
Kumar, Vikash;
Behl, Ankita;
Abid, Mohammad;
Garg, Swati;
Gupta, Sonal;
Singh, Shailja

Publication type:

Article

Erythrocyte sphingosine kinase regulates intraerythrocytic development of Plasmodium falciparum.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80658-7

By:

Sah, Raj Kumar;
Pati, Soumya;
Saini, Monika;
Singh, Shailja

Publication type:

Article

Prefoldin subunit 6 of Plasmodium falciparum binds merozoite surface protein-1.

Published in:

FEBS Open Bio, 2022, v. 12, n. 5, p. 1050, doi. 10.1002/2211-5463.13022

By:

Kumar, Vikash;
Shoaib, Rumaisha;
Behl, Ankita;
Munjal, Akshay;
Abid, Mohammad;
Singh, Shailja

Publication type:

Article

Prevalence of Autoantibodies and HLA DR, DQ in Type 1 Diabetes Mellitus.

Published in:

Journal of Clinical & Diagnostic Research, 2016, v. 10, n. 7, p. 9, doi. 10.7860/JCDR/2016/18657.8163

By:

SINGH, SHAILJA;
USHA;
SINGH, GYANENDRA;
AGRAWAL, NEERAJ KUMAR;
SINGH, RANA GOPAL;
KUMAR, SHASHI BHUSHAN

Publication type:

Article

Pleiotropic roles of cold shock proteins with special emphasis on unexplored cold shock protein member of Plasmodium falciparum.

Published in:

2020

By:

Behl, Ankita;
Kumar, Vikash;
Shevtsov, Maxim;
Singh, Shailja

Publication type:

Literature Review

Correction to: Enhanced uptake, high selective and microtubule disrupting activity of carbohydrate fused pyrano-pyranones derived from natural coumarins attributes to its anti-malarial potential.

Published in:

2020

By:

Gupta, Sonal;
Khan, Juveria;
Kumari, Priti;
Narayana, Chintam;
Ayana, R.;
Chakrabarti, Malabika;
Sagar, Ram;
Singh, Shailja

Publication type:

Correction Notice

Enhanced uptake, high selective and microtubule disrupting activity of carbohydrate fused pyrano-pyranones derived from natural coumarins attributes to its anti-malarial potential.

Published in:

Malaria Journal, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1186/s12936-019-2971-z

By:

Gupta, Sonal;
Khan, Juveria;
Kumari, Priti;
Narayana, Chintam;
Ayana, R.;
Chakrabarti, Malabika;
Sagar, Ram;
Singh, Shailja

Publication type:

Article

Toxin-antitoxin systems and their medical applications: current status and future perspective.

Published in:

Applied Microbiology & Biotechnology, 2021, v. 105, n. 5, p. 1803, doi. 10.1007/s00253-021-11134-z

By:

Srivastava, Akriti;
Pati, Soumya;
Kaushik, Himani;
Singh, Shailja;
Garg, Lalit C.

Publication type:

Article

Spatiotemporal variations, sources, pollution status and health risk assessment of dissolved trace elements in a major Arabian Sea draining river: insights from multivariate statistical and machine learning approaches.

Published in:

Environmental Geochemistry & Health, 2024, v. 46, n. 4, p. 1, doi. 10.1007/s10653-024-01885-9

By:

Singh, Shailja;
Das, Anirban;
Sharma, Paawan;
Sudheer, A. K.;
Gaddam, Mahesh;
Ranjan, Rajnee

Publication type:

Article

Plasmodium palmitoylation machinery engineered in E. coli for high‐throughput screening of palmitoyl acyl‐transferase inhibitors.

Published in:

FEBS Open Bio, 2019, v. 9, n. 2, p. 248, doi. 10.1002/2211-5463.12564

By:

Yadav, Preeti;
Ayana, R;
Garg, Swati;
Jain, Ravi;
Sah, Raj;
Joshi, Nishant;
Pati, Soumya;
Singh, Shailja

Publication type:

Article

Pathogenic Pore Forming Proteins of Plasmodium Triggers the Necrosis of Endothelial Cells Attributed to Malaria Severity.

Published in:

Toxins, 2021, v. 13, n. 1, p. 62, doi. 10.3390/toxins13010062

By:

Shivappagowdar, Abhishek;
Garg, Swati;
Srivastava, Akriti;
Hada, Rahul S.;
Kalia, Inderjeet;
Singh, Agam P.;
Garg, Lalit C.;
Pati, Soumya;
Singh, Shailja

Publication type:

Article

An Update on the Morphology, Mechanism, Lethality and Management of Amanita Phalloides.

Published in:

Journal of Punjab Academy of Forensic Medicine & Toxicology, 2024, v. 24, n. 1, p. 142, doi. 10.5958/0974-083X.2024.00024.0

By:

Singh, Shailja;
Batta, Kajol;
Saharan, Sameer;
Sinha, Vaishali

Publication type:

Article

Characterization of thiamine pyrophosphokinase of vitamin B1 biosynthetic pathway as a drug target of Leishmania donovani.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 11, p. 5669, doi. 10.1080/07391102.2023.2227718

By:

Ranjan Kumar, Ravi;
Jain, Ravi;
Akhtar, Sabir;
Parveen, Nidha;
Ghosh, Arabinda;
Sharma, Veena;
Singh, Shailja

Publication type:

Article

Screening of traditional medicinal plant extracts and compounds identifies a potent anti-leishmanial diarylheptanoid from Siphonochilus aethiopicus.

Published in:

Journal of Biomolecular Structure & Dynamics, 2024, v. 42, n. 5, p. 2449, doi. 10.1080/07391102.2023.2212779

By:

Ezenyi, Ifeoma;
Madan, Evanka;
Singhal, Jhalak;
Jain, Ravi;
Chakrabarti, Amrita;
Ghousepeer, Gajala Deethamvali;
Pandey, Ramendra Pati;
Igoli, Ngozichukwuka;
Igoli, John;
Singh, Shailja

Publication type:

Article

Antimalarial and Plasmodium falciparum serpentine receptor 12 targeting effect of FDA approved purinergic receptor antagonist.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 19, p. 9462, doi. 10.1080/07391102.2022.2142298

By:

Gupta, Sonal;
Saini, Monika;
Joshi, Nishant;
Shafi, Sadat;
Najmi, Abul Kalam;
Singh, Shailja

Publication type:

Article

A multi-spectroscopic and computational simulations study to delineate the interaction between antimalarial drug hydroxychloroquine and human serum albumin.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 13, p. 6377, doi. 10.1080/07391102.2022.2107077

By:

Azeem, Kashish;
Ahmed, Mofieed;
Mohammad, Taj;
Uddin, Amad;
Shamsi, Anas;
Hassan, Md. Imtaiyaz;
Singh, Shailja;
Patel, Rajan;
Abid, Mohammad

Publication type:

Article

Computational assessment of Withania somnifera phytomolecules as putative inhibitors of Mycobacterium tuberculosis CTP synthase PyrG.

Published in:

Journal of Biomolecular Structure & Dynamics, 2023, v. 41, n. 11, p. 4903, doi. 10.1080/07391102.2022.2074142

By:

Singh, Ankita;
Kumar, Sanjay;
Gupta, Vivek Kumar;
Singh, Shailja;
Dwivedi, Vivek Dhar;
Mina, Usha

Publication type:

Article

Highly potent anti-malarial activity of benzopyrano(4,3-b)benzopyran derivatives and in silico interaction analysis with putative target Plasmodium falciparum lactate dehydrogenase.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 11, p. 5159, doi. 10.1080/07391102.2020.1868336

By:

Joshi, Nishant;
Hada, Rahul;
Gupta, Sonal;
Khan, Juveria;
Dobrowolski, Jeremy;
Dhar, Pawan K.;
Kumar, Naresh;
Singh, Shailja

Publication type:

Article

Comparative structural insight into prefoldin subunints of archaea and eukaryotes with special emphasis on unexplored prefoldin of Plasmodium falciparum.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 8, p. 3804, doi. 10.1080/07391102.2020.1850527

By:

Kumar, Vikash;
Behl, Ankita;
Shoaib, Rumaisha;
Abid, Mohammad;
Shevtsov, Maxim;
Singh, Shailja

Publication type:

Article

Cyclic peptide engineered from phytocystatin inhibitory hairpin loop as an effective modulator of falcipains and potent antimalarial.

Published in:

Journal of Biomolecular Structure & Dynamics, 2022, v. 40, n. 8, p. 3642, doi. 10.1080/07391102.2020.1848629

By:

Mishra, Manasi;
Singh, Vigyasa;
Tellis, Meenakshi B.;
Joshi, Rakesh S.;
Pandey, Kailash C.;
Singh, Shailja

Publication type:

Article

Targeting metacaspase-3 from Plasmodium falciparum towards antimalarial therapy: A combined approach of in-silico and in-vitro investigation.

Published in:

Journal of Biomolecular Structure & Dynamics, 2021, v. 39, n. 2, p. 421, doi. 10.1080/07391102.2019.1711194

By:

Kumar, Bhumika;
Mohammad, Taj;
Amaduddin;
Hussain, Afzal;
Islam, Asimul;
Ahmad, Faizan;
Alajmi, Mohamed F.;
Singh, Shailja;
Pandey, Kailash C.;
Hassan, Md. Imtaiyaz;
Abid, Mohammad

Publication type:

Article

Quality of Life of Ostomates with the Selected Factors in a Selected Hospital of Delhi with a View to Develop Guidelines for the Health Professionals.

Published in:

Indian Journal of Palliative Care, 2009, v. 15, n. 2, p. 111, doi. 10.4103/0973-1075.58455

By:

Sinha, Aditi;
Goyal, Harinderjeet;
Singh, Shailja;
Rana, Shiv Pratap Singh

Publication type:

Article

Target-Based Virtual Screening of Natural Compounds Identifies a Potent Antimalarial With Selective Falcipain-2 Inhibitory Activity.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.850176

By:

Uddin, Amad;
Gupta, Sonal;
Mohammad, Taj;
Shahi, Diksha;
Hussain, Afzal;
Alajmi, Mohamed F.;
El-Seedi, Hesham R.;
Hassan, Imtaiyaz;
Singh, Shailja;
Abid, Mohammad

Publication type:

Article

Sphingosine 1-Phosphate in Malaria Pathogenesis and Its Implication in Therapeutic Opportunities.

Published in:

Frontiers in Cellular & Infection Microbiology, 2020, v. 10, p. N.PAG, doi. 10.3389/fcimb.2020.00353

By:

Dhangadamajhi, Gunanidhi;
Singh, Shailja

Publication type:

Article

Plasmodium Perforin-Like Protein Pores on the Host Cell Membrane Contribute in Its Multistage Growth and Erythrocyte Senescence.

Published in:

Frontiers in Cellular & Infection Microbiology, 2020, p. 1, doi. 10.3389/fcimb.2020.00121

By:

Garg, Swati;
Shivappagowdar, Abhishek;
Hada, Rahul S.;
Ayana, Rajagopal;
Bathula, Chandramohan;
Sen, Subhabrata;
Kalia, Inderjeet;
Pati, Soumya;
Singh, Agam P.;
Singh, Shailja

Publication type:

Article

Molecular dynamics simulations and biochemical characterization of Pf14-3-3 and PfCDPK1 interaction towards its role in growth of human malaria parasite.

Published in:

Biochemical Journal, 2020, v. 477, n. 12, p. 2153, doi. 10.1042/BCJ20200145

By:

Jain, Ravi;
Dey, Pinki;
Gupta, Sakshi;
Pati, Soumya;
Bhattacherjee, Arnab;
Munde, Manoj;
Singh, Shailja

Publication type:

Article

Development of novel anti-malarial from structurally diverse library of molecules, targeting plant-like CDPK1, a multistage growth regulator of P. falciparum.

Published in:

Biochemical Journal, 2020, v. 477, n. 10, p. 1951, doi. 10.1042/BCJ20200045

By:

Jain, Ravi;
Gupta, Sakshi;
Munde, Manoj;
Pati, Soumya;
Singh, Shailja

Publication type:

Article

Enhanced antibacterial properties and the cellular response of stainless steel through friction stir processing.

Published in:

Biofouling, 2019, v. 35, n. 2, p. 187, doi. 10.1080/08927014.2019.1584794

By:

Perumal, Gopinath;
Chakrabarti, Amrita;
Grewal, Harpreet S.;
Pati, Soumya;
Singh, Shailja;
Arora, Harpreet S.

Publication type:

Article

Natural Product Inspired Novel Indole based Chiral Scaffold Kills Human Malaria Parasites via Ionic Imbalance Mediated Cell Death.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-54339-z

By:

Dangi, Poonam;
Jain, Ravi;
Mamidala, Rajanikanth;
Sharma, Vijeta;
Agarwal, Shalini;
Bathula, Chandramohan;
Thirumalachary, M.;
Sen, Subhabrata;
Singh, Shailja

Publication type:

Article

A testis-expressing heme peroxidase HPX12 regulates male fertility in the mosquito Anopheles stephensi.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-06531-x

By:

Kumari, Seena;
Tevatiya, Sanjay;
Rani, Jyoti;
Das De, Tanwee;
Chauhan, Charu;
Sharma, Punita;
Sah, Rajkumar;
Singh, Shailja;
Pandey, Kailash C.;
Pande, Veena;
Dixit, Rajnikant

Publication type:

Article

Role of HLA alleles polymorphism in systemic lupus erythematosus: A prospective study from North India.

Published in:

Indian Journal of Pathology & Microbiology, 2023, v. 66, n. 3, p. 545, doi. 10.4103/ijpm.ijpm_764_21

By:

Rana, Ranjan S.;
Naik, Bitan;
Yadav, Mahima;
Singh, Usha;
Singh, Anup;
Singh, Shailja

Publication type:

Article