Works by Simuni, Tanya


Results: 117
    1

    Time-to-event analysis mitigates the impact of symptomatic therapy on therapeutic benefit in Parkinson's disease trials.

    Published in:
    NPJ Parkinson's Disease, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41531-025-01041-9
    By:
    • Pagano, Gennaro;
    • Trundell, Dylan;
    • Simuni, Tanya;
    • Pavese, Nicola;
    • Marek, Kenneth;
    • Postuma, Ronald B.;
    • Shariati, Nima;
    • Monnet, Annabelle;
    • Moore, Emma;
    • Davies, Evan W.;
    • Svoboda, Hanno;
    • Pross, Nathalie;
    • Bonni, Azad;
    • Nikolcheva, Tania;
    • Altendorf, Claudia;
    • Anandan, Chareyna;
    • Andrews, Giulia;
    • Ansquer, Solène;
    • Arrouasse, Raphaele;
    • Aslam, Sana
    Publication type:
    Article
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    A Phase II Study to Evaluate the Safety and Efficacy of Prasinezumab in Early Parkinson's Disease (PASADENA): Rationale, Design, and Baseline Data.

    Published in:
    Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.705407
    By:
    • Pagano, Gennaro;
    • Boess, Frank G.;
    • Taylor, Kirsten I.;
    • Ricci, Benedicte;
    • Mollenhauer, Brit;
    • Poewe, Werner;
    • Boulay, Anne;
    • Anzures-Cabrera, Judith;
    • Vogt, Annamarie;
    • Marchesi, Maddalena;
    • Post, Anke;
    • Nikolcheva, Tania;
    • Kinney, Gene G.;
    • Zago, Wagner M.;
    • Ness, Daniel K.;
    • Svoboda, Hanno;
    • Britschgi, Markus;
    • Ostrowitzki, Susanne;
    • Simuni, Tanya;
    • Marek, Kenneth
    Publication type:
    Article
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    Subcutaneous Levodopa Infusion for Parkinson's Disease: 1‐Year Data from the Open‐Label BeyoND Study.

    Published in:
    Movement Disorders, 2021, v. 36, n. 11, p. 2687, doi. 10.1002/mds.28758
    By:
    • Poewe, Werner;
    • Stocchi, Fabrizio;
    • Arkadir, David;
    • Ebersbach, Georg;
    • Ellenbogen, Aaron L.;
    • Giladi, Nir;
    • Isaacson, Stuart H.;
    • Kieburtz, Karl;
    • LeWitt, Peter;
    • Olanow, C. Warren;
    • Simuni, Tanya;
    • Thomas, Astrid;
    • Zlotogorski, Abraham;
    • Adar, Liat;
    • Case, Ryan;
    • Oren, Sheila;
    • Fuchs Orenbach, Shir;
    • Rosenfeld, Olivia;
    • Sasson, Nissim;
    • Yardeni, Tami
    Publication type:
    Article
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    Longitudinal Analysis of Multiple Neurotransmitter Metabolites in Cerebrospinal Fluid in Early Parkinson's Disease.

    Published in:
    Movement Disorders, 2021, v. 36, n. 8, p. 1972, doi. 10.1002/mds.28608
    By:
    • Kremer, Thomas;
    • Taylor, Kirsten I.;
    • Siebourg‐Polster, Juliane;
    • Gerken, Thomas;
    • Staempfli, Andreas;
    • Czech, Christian;
    • Dukart, Juergen;
    • Galasko, Douglas;
    • Foroud, Tatiana;
    • Chahine, Lana M.;
    • Coffey, Christopher S.;
    • Simuni, Tanya;
    • Weintraub, Daniel;
    • Seibyl, John;
    • Poston, Kathleen L.;
    • Toga, Arthur W.;
    • Tanner, Caroline M.;
    • Marek, Kenneth;
    • Hutten, Samantha J.;
    • Dziadek, Sebastian
    Publication type:
    Article
    13

    Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson's Disease Progression.

    Published in:
    Movement Disorders, 2020, v. 35, n. 11, p. 1999, doi. 10.1002/mds.28206
    By:
    • Mollenhauer, Brit;
    • Dakna, Mohammed;
    • Kruse, Niels;
    • Galasko, Douglas;
    • Foroud, Tatiana;
    • Zetterberg, Henrik;
    • Schade, Sebastian;
    • Gera, Roland G.;
    • Wang, Wenting;
    • Gao, Feng;
    • Frasier, Mark;
    • Chahine, Lana M.;
    • Coffey, Christopher S.;
    • Singleton, Andrew B.;
    • Simuni, Tanya;
    • Weintraub, Daniel;
    • Seibyl, John;
    • Toga, Arthur W.;
    • Tanner, Caroline M.;
    • Kieburtz, Karl
    Publication type:
    Article
    14

    Clinical and Imaging Progression in the PARS Cohort: Long-Term Follow-up.

    Published in:
    2020
    By:
    • Siderowf, Andrew;
    • Jennings, Danna;
    • Stern, Matthew;
    • Seibyl, John;
    • Eberly, Shirley;
    • Oakes, David;
    • Marek, Kenneth;
    • Marek, Ken;
    • Russell, David;
    • Sethi, Kapil;
    • Frank, Samuel;
    • Simuni, Tanya;
    • Hauser, Robert;
    • Ravina, Bernard;
    • Richards, Irene;
    • Liang, Grace;
    • Adler, Charles;
    • Saunders‐Pullman, Rachel;
    • Evatt, Marian L.;
    • Lai, Eugene
    Publication type:
    journal article
    15

    Clinical and Dopamine Transporter Imaging Characteristics of Leucine Rich Repeat Kinase 2 (LRRK2) and Glucosylceramidase Beta (GBA) Parkinson's Disease Participants in the Parkinson's Progression Markers Initiative: A Cross-Sectional Study.

    Published in:
    2020
    By:
    • Simuni, Tanya;
    • Brumm, Michael C.;
    • Uribe, Liz;
    • Caspell‐Garcia, Chelsea;
    • Coffey, Christopher S.;
    • Siderowf, Andrew;
    • Alcalay, Roy N.;
    • Trojanowski, John Q.;
    • Shaw, Leslie M.;
    • Seibyl, John;
    • Singleton, Andrew;
    • Toga, Arthur W.;
    • Galasko, Doug;
    • Foroud, Tatiana;
    • Nudelman, Kelly;
    • Tosun‐Turgut, Duygu;
    • Poston, Kathleen;
    • Weintraub, Daniel;
    • Mollenhauer, Brit;
    • Tanner, Caroline M.
    Publication type:
    journal article
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    Longitudinal Change of Clinical and Biological Measures in Early Parkinson's Disease: Parkinson's Progression Markers Initiative Cohort.

    Published in:
    2018
    By:
    • Simuni, Tanya;
    • Siderowf, Andrew;
    • Lasch, Shirley;
    • Coffey, Chris S.;
    • Caspell‐Garcia, Chelsea;
    • Jennings, Danna;
    • Tanner, Caroline M.;
    • Trojanowski, John Q.;
    • Shaw, Leslie M.;
    • Seibyl, John;
    • Schuff, Norbert;
    • Singleton, Andrew;
    • Kieburtz, Karl;
    • Toga, Arthur W.;
    • Mollenhauer, Brit;
    • Galasko, Doug;
    • Chahine, Lana M.;
    • Weintraub, Daniel;
    • Foroud, Tatiana;
    • Tosun, Duygu
    Publication type:
    journal article
    18

    Technology in Parkinson's disease: Challenges and opportunities.

    Published in:
    2016
    By:
    • Espay, Alberto J.;
    • Bonato, Paolo;
    • Nahab, Fatta B.;
    • Maetzler, Walter;
    • Dean, John M.;
    • Klucken, Jochen;
    • Eskofier, Bjoern M.;
    • Merola, Aristide;
    • Horak, Fay;
    • Lang, Anthony E.;
    • Reilmann, Ralf;
    • Giuffrida, Joe;
    • Nieuwboer, Alice;
    • Horne, Malcolm;
    • Little, Max A.;
    • Litvan, Irene;
    • Simuni, Tanya;
    • Dorsey, E. Ray;
    • Burack, Michelle A.;
    • Kubota, Ken
    Publication type:
    journal article
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    Cognitive performance and neuropsychiatric symptoms in early, untreated Parkinson's disease.

    Published in:
    Movement Disorders, 2015, v. 30, n. 7, p. 919, doi. 10.1002/mds.26170
    By:
    • Weintraub, Daniel;
    • Simuni, Tanya;
    • Caspell‐Garcia, Chelsea;
    • Coffey, Christopher;
    • Lasch, Shirley;
    • Siderowf, Andrew;
    • Aarsland, Dag;
    • Barone, Paolo;
    • Burn, David;
    • Chahine, Lama M.;
    • Eberling, Jamie;
    • Espay, Alberto J.;
    • Foster, Eric D.;
    • Leverenz, James B.;
    • Litvan, Irene;
    • Richard, Irene;
    • Troyer, Matthew D.;
    • Hawkins, Keith A.
    Publication type:
    Article
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    A recommended scale for cognitive screening in clinical trials of Parkinson's disease.

    Published in:
    Movement Disorders, 2010, v. 25, n. 15, p. 2501, doi. 10.1002/mds.23362
    By:
    • Chou, Kelvin L.;
    • Amick, Melissa M.;
    • Brandt, Jason;
    • Camicioli, Richard;
    • Frei, Karen;
    • Gitelman, Darren;
    • Goldman, Jennifer;
    • Growdon, John;
    • Hurtig, Howard I.;
    • Levin, Bonnie;
    • Litvan, Irene;
    • Marsh, Laura;
    • Simuni, Tanya;
    • Tröster, Alexander I.;
    • Uc, Ergun Y.
    Publication type:
    Article
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    An Acetylcholine M<sub>1</sub> Receptor–Positive Allosteric Modulator (TAK-071) in Parkinson Disease With Cognitive Impairment: A Phase 2 Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2025, v. 82, n. 2, p. 152, doi. 10.1001/jamaneurol.2024.4519
    By:
    • Shanbhag, Niraj M.;
    • Padmanabhan, Jaya L.;
    • Zhang, Zheng;
    • Harel, Brian T.;
    • Jia, Hongxia;
    • Kangarloo, Tairmae;
    • Yin, Wei;
    • Dowling, Ariel V.;
    • Laurenza, Antonio;
    • Khudyakov, Polyna;
    • Galinsky, Kevin;
    • Latzman, Robert D.;
    • Simuni, Tanya;
    • Weintraub, Daniel;
    • Horak, Fay B.;
    • Lustig, Cindy;
    • Maruff, Paul;
    • Simen, Arthur A.
    Publication type:
    Article
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    Efficacy of Nilotinib in Patients With Moderately Advanced Parkinson Disease: A Randomized Clinical Trial.

    Published in:
    JAMA Neurology, 2021, v. 78, n. 3, p. 312, doi. 10.1001/jamaneurol.2020.4725
    By:
    • Simuni, Tanya;
    • Fiske, Brian;
    • Merchant, Kalpana;
    • Coffey, Christopher S.;
    • Klingner, Elizabeth;
    • Caspell-Garcia, Chelsea;
    • Lafontant, David-Erick;
    • Matthews, Helen;
    • Wyse, Richard K.;
    • Brundin, Patrik;
    • Simon, David K.;
    • Schwarzschild, Michael;
    • Weiner, David;
    • Adams, Jamie;
    • Venuto, Charles;
    • Dawson, Ted M.;
    • Baker, Liana;
    • Kostrzebski, Melissa;
    • Ward, Tina;
    • Rafaloff, Gary
    Publication type:
    Article
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    Association of Cerebrospinal Fluid β-Amyloid 1-42, T-tau, P-tau<sub>181</sub>, and α-Synuclein Levels With Clinical Features of Drug-Naive Patients With Early Parkinson Disease.

    Published in:
    JAMA Neurology, 2013, v. 70, n. 10, p. 1277, doi. 10.1001/jamaneurol.2013.3861
    By:
    • Ju-Hee Kang;
    • Irwin, David J.;
    • Chen-Plotkin, Alice S.;
    • Siderowf, Andrew;
    • Caspell, Chelsea;
    • Coffey, Christopher S.;
    • Waligórska, Teresa;
    • Taylor, Peggy;
    • Pan, Sarah;
    • Frasier, Mark;
    • Marek, Kenneth;
    • Kieburtz, Karl;
    • Jennings, Danna;
    • Simuni, Tanya;
    • Tanner, Caroline M.;
    • Singleton, Andrew;
    • Toga, Arthur W.;
    • Chowdhury, Sohini;
    • Mollenhauer, Brit;
    • Trojanowski, John Q.
    Publication type:
    Article
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    Advance care planning in Parkinson's disease: ethical challenges and future directions.

    Published in:
    NPJ Parkinson's Disease, 2019, v. 5, n. 1, p. N.PAG, doi. 10.1038/s41531-019-0098-0
    By:
    • Sokol, Leonard L.;
    • Young, Michael J.;
    • Paparian, Jack;
    • Kluger, Benzi M.;
    • Lum, Hillary D.;
    • Besbris, Jessica;
    • Kramer, Neha M.;
    • Lang, Anthony E.;
    • Espay, Alberto J.;
    • Dubaz, Ornella M.;
    • Miyasaki, Janis M.;
    • Matlock, Daniel D.;
    • Simuni, Tanya;
    • Cerf, Moran
    Publication type:
    Article
    40

    Treatment of Early Parkinson’s Disease.

    Published in:
    European Neurology, 2009, v. 61, n. 4, p. 193, doi. 10.1159/000197103
    By:
    • Simuni, Tanya;
    • Lyons, Kelly E.;
    • Pahwa, Rajesh;
    • Hauser, Robert A.;
    • Comella, Cynthia;
    • Elmer, Lawrence;
    • Weintraub, Daniel
    Publication type:
    Article
    41

    Treatment of Early Parkinson’s Disease.

    Published in:
    European Neurology, 2009, v. 61, n. 4, p. 206, doi. 10.1159/000197104
    By:
    • Simuni, Tanya;
    • Lyons, Kelly E.;
    • Pahwa, Rajesh;
    • Hauser, Robert A.;
    • Comella, Cynthia;
    • Elmer, Lawrence;
    • Weintraub, Daniel
    Publication type:
    Article
    42

    Overcoming obstacles to repurposing for neurodegenerative disease.

    Published in:
    Annals of Clinical & Translational Neurology, 2014, v. 1, n. 7, p. 512, doi. 10.1002/acn3.76
    By:
    • Shineman, Diana W.;
    • Alam, John;
    • Anderson, Margaret;
    • Black, Sandra E.;
    • Carman, Aaron J.;
    • Cummings, Jeffrey L.;
    • Dacks, Penny A.;
    • Dudley, Joel T.;
    • Frail, Donald E.;
    • Green, Allan;
    • Lane, Rachel F.;
    • Lappin, Debra;
    • Simuni, Tanya;
    • Stefanacci, Richard G.;
    • Sherer, Todd;
    • Fillit, Howard M.
    Publication type:
    Article
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    Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease.

    Published in:
    PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0175674
    By:
    • Caspell-Garcia, Chelsea;
    • Simuni, Tanya;
    • Tosun-Turgut, Duygu;
    • Wu, I-Wei;
    • Zhang, Yu;
    • Nalls, Mike;
    • Singleton, Andrew;
    • Shaw, Leslie A.;
    • Kang, Ju-Hee;
    • Trojanowski, John Q.;
    • Siderowf, Andrew;
    • Coffey, Christopher;
    • Lasch, Shirley;
    • Aarsland, Dag;
    • Burn, David;
    • Chahine, Lana M.;
    • Espay, Alberto J.;
    • Foster, Eric D.;
    • Hawkins, Keith A.;
    • Litvan, Irene
    Publication type:
    Article
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